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Aliases for ANKRD36B Gene

Aliases for ANKRD36B Gene

  • Ankyrin Repeat Domain 36B 2 3 5
  • CLL-Associated Antigen KW-1 2 3 4
  • Melanoma-Associated Antigen 2 3
  • KIAA1641 2 3
  • Ankyrin Repeat Domain-Containing Protein 36B 3

External Ids for ANKRD36B Gene

Previous HGNC Symbols for ANKRD36B Gene

  • KIAA1641

Previous GeneCards Identifiers for ANKRD36B Gene

  • GC02M098108

Summaries for ANKRD36B Gene

GeneCards Summary for ANKRD36B Gene

ANKRD36B (Ankyrin Repeat Domain 36B) is a Protein Coding gene. Diseases associated with ANKRD36B include Melanoma. An important paralog of this gene is ANKRD36C.

Additional gene information for ANKRD36B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD36B Gene

Genomics for ANKRD36B Gene

Regulatory Elements for ANKRD36B Gene

Enhancers for ANKRD36B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H097589 1 ENCODE 47.4 -0.3 -253 2 HDGF PKNOX1 ATF1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 ANKRD36B COX5B ACTR1B RNU4-8P C2orf92 ZAP70 LOC105373499
GH02H097660 1.4 ENCODE dbSUPER 33.2 -72.5 -72549 4 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B YY1 SLC30A9 ZNF766 ANKRD36B TMEM131 ZAP70 UNC50 CNNM3 LOC100506123 C2orf92 ACTR1B PIR38581
GH02H097673 1.4 FANTOM5 ENCODE dbSUPER 33.2 -83.5 -83506 1 TBP PKNOX1 ATF1 TBL1XR1 BMI1 TCF12 ZNF766 ATF7 ETV6 RUNX3 ANKRD36B COX5B ZAP70 FAHD2B TMEM131 PIR32897 RNU4-8P
GH02H097712 1.8 FANTOM5 Ensembl ENCODE dbSUPER 24.2 -126.0 -125981 7 PKNOX1 ATF1 TCF12 ZNF766 CAVIN1 ZNF592 KAT8 MEF2D MIER3 SMARCA4 ZAP70 ANKRD36B LMAN2L UNC50 ACTR1B ANKRD36 CNNM3 SEMA4C TMEM131 FAHD2B
GH02H097992 1.4 ENCODE dbSUPER 23.6 -404.7 -404705 4 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZBTB7B ANKRD36B UNC50 TMEM131 ANKRD36 ZAP70 ACTR1B C2orf92 RNU7-96P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKRD36B on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD36B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000120379 345 2601 HDGF PKNOX1 ATF1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143

Genomic Location for ANKRD36B Gene

Chromosome:
2
Start:
97,492,663 bp from pter
End:
97,590,245 bp from pter
Size:
97,583 bases
Orientation:
Minus strand

Genomic View for ANKRD36B Gene

Genes around ANKRD36B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD36B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD36B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD36B Gene

Proteins for ANKRD36B Gene

  • Protein details for ANKRD36B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N2N9-AN36B_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 36B
    Protein Accession:
    Q8N2N9
    Secondary Accessions:
    • Q08AK5
    • Q6IPR0
    • Q6PI49
    • Q8IZM7
    • Q8TDH6
    • Q96N30
    • Q9H759

    Protein attributes for ANKRD36B Gene

    Size:
    1353 amino acids
    Molecular mass:
    153582 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI25133.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI25134.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAL99915.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB15039.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB71081.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD36B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD36B Gene

Post-translational modifications for ANKRD36B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKRD36B Gene

Domains & Families for ANKRD36B Gene

Gene Families for ANKRD36B Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKRD36B Gene

Suggested Antigen Peptide Sequences for ANKRD36B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N2N9

UniProtKB/Swiss-Prot:

AN36B_HUMAN :
  • Belongs to the ANKRD36 family.
Family:
  • Belongs to the ANKRD36 family.
genes like me logo Genes that share domains with ANKRD36B: view

Function for ANKRD36B Gene

Phenotypes From GWAS Catalog for ANKRD36B Gene

Gene Ontology (GO) - Molecular Function for ANKRD36B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ANKRD36B: view

Phenotypes for ANKRD36B Gene

GenomeRNAi human phenotypes for ANKRD36B:
genes like me logo Genes that share phenotypes with ANKRD36B: view

Animal Model Products

CRISPR Products

miRNA for ANKRD36B Gene

miRTarBase miRNAs that target ANKRD36B

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD36B Gene

Localization for ANKRD36B Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD36B Gene

Pathways & Interactions for ANKRD36B Gene

SuperPathways for ANKRD36B Gene

No Data Available

Interacting Proteins for ANKRD36B Gene

Gene Ontology (GO) - Biological Process for ANKRD36B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD36B Gene

Drugs & Compounds for ANKRD36B Gene

No Compound Related Data Available

Transcripts for ANKRD36B Gene

Unigene Clusters for ANKRD36B Gene

Ankyrin repeat domain 36B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD36B Gene

No ASD Table

Relevant External Links for ANKRD36B Gene

GeneLoc Exon Structure for
ANKRD36B
ECgene alternative splicing isoforms for
ANKRD36B

Expression for ANKRD36B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD36B Gene

Protein differential expression in normal tissues from HIPED for ANKRD36B Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKRD36B Gene



Protein tissue co-expression partners for ANKRD36B Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ANKRD36B Gene:

ANKRD36B

SOURCE GeneReport for Unigene cluster for ANKRD36B Gene:

Hs.532921
genes like me logo Genes that share expression patterns with ANKRD36B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD36B Gene

Orthologs for ANKRD36B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ANKRD36B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD36B 33
  • 97.89 (n)
Species where no ortholog for ANKRD36B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD36B Gene

ENSEMBL:
Gene Tree for ANKRD36B (if available)
TreeFam:
Gene Tree for ANKRD36B (if available)

Paralogs for ANKRD36B Gene

genes like me logo Genes that share paralogs with ANKRD36B: view

Variants for ANKRD36B Gene

Sequence variations from dbSNP and Humsavar for ANKRD36B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000019310 -- 97,548,044(+) AGAGG(A/T)GAAAC intron-variant
rs1000056008 -- 97,567,851(+) TTCAC(A/G)GATCC intron-variant
rs1000189310 -- 97,586,685(+) TTGCT(A/C)ATTTT intron-variant
rs1000243691 -- 97,498,526(+) GATGT(A/G)TTCAA intron-variant
rs1000349619 -- 97,590,783(+) GGCAG(A/G)TGTGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ANKRD36B Gene

Variant ID Type Subtype PubMed ID
dgv1145e212 CNV gain 25503493
dgv1147e212 CNV loss 25503493
dgv1148e212 CNV loss 25503493
dgv1149e212 CNV gain 25503493
dgv1150e212 CNV gain 25503493
dgv1151e212 CNV loss 25503493
dgv1152e212 CNV gain 25503493
dgv1153e212 CNV loss 25503493
dgv1154e212 CNV loss 25503493
dgv1975n106 CNV deletion 24896259
dgv1976n106 CNV deletion 24896259
dgv2200e59 CNV duplication 20981092
dgv4010n100 CNV gain 25217958
dgv4015n100 CNV gain+loss 25217958
dgv4016n100 CNV loss 25217958
dgv4024n100 CNV gain 25217958
dgv4025n100 CNV gain 25217958
dgv4026n100 CNV gain 25217958
dgv607e201 CNV deletion 23290073
dgv721e199 CNV deletion 23128226
esv2422044 CNV deletion 20811451
esv25217 CNV gain 19812545
esv2662364 CNV deletion 23128226
esv2720423 CNV deletion 23290073
esv2759077 CNV gain+loss 17122850
esv2760569 CNV loss 21179565
esv2763630 CNV gain+loss 21179565
esv3130456 CNV deletion 24192839
esv32869 CNV loss 17666407
esv3425717 CNV duplication 20981092
esv3442636 CNV duplication 20981092
esv3575270 CNV gain 25503493
esv3575281 CNV gain 25503493
esv3575285 CNV gain 25503493
esv3583977 CNV loss 25503493
esv3591709 CNV loss 21293372
esv3591710 CNV gain 21293372
esv3591711 CNV loss 21293372
esv3591712 CNV loss 21293372
esv3591713 CNV gain 21293372
esv3591714 CNV loss 21293372
esv3591715 CNV gain 21293372
esv998247 CNV insertion 20482838
nsv1004566 CNV loss 25217958
nsv1008339 CNV gain+loss 25217958
nsv10099 CNV gain 18304495
nsv10100 CNV loss 18304495
nsv10101 CNV gain 18304495
nsv10102 CNV gain 18304495
nsv1010893 CNV gain 25217958
nsv1071604 CNV deletion 25765185
nsv1122004 CNV deletion 24896259
nsv1123360 CNV deletion 24896259
nsv1125311 OTHER inversion 24896259
nsv1127755 CNV deletion 24896259
nsv1135873 CNV deletion 24896259
nsv1147402 CNV duplication 26484159
nsv1148339 CNV duplication 26484159
nsv1148786 OTHER inversion 26484159
nsv1160829 CNV deletion 26073780
nsv2836 CNV insertion 18451855
nsv442803 CNV loss 18776908
nsv499474 CNV gain 21111241
nsv508852 CNV insertion 20534489
nsv522486 CNV gain 19592680
nsv7323 OTHER inversion 18451855
nsv820699 CNV deletion 20802225
nsv953488 CNV duplication 24416366
nsv961839 CNV duplication 23825009
nsv963829 CNV duplication 23825009
nsv997395 CNV loss 25217958
nsv999561 CNV loss 25217958

Relevant External Links for ANKRD36B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD36B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ANKRD36B Gene

Disorders for ANKRD36B Gene

MalaCards: The human disease database

(1) MalaCards diseases for ANKRD36B Gene - From: Novoseek and GeneCards

Disorder Aliases PubMed IDs
melanoma
  • malignant melanoma
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ANKRD36B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD36B
genes like me logo Genes that share disorders with ANKRD36B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ANKRD36B Gene

Publications for ANKRD36B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 60
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 60
  5. Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. (PMID: 26460568) Johnson-Kerner BL … Wichterle H (PloS one 2015) 3 60

Products for ANKRD36B Gene

Sources for ANKRD36B Gene

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