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Aliases for ANKRD36 Gene

Aliases for ANKRD36 Gene

  • Ankyrin Repeat Domain 36 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 36 3
  • Ankyrin-Related 3
  • ANKRD36A 4
  • KIAA1641 4
  • UNQ2430 3

External Ids for ANKRD36 Gene

Previous GeneCards Identifiers for ANKRD36 Gene

  • GC02P097202
  • GC02P097782
  • GC02P091738

Summaries for ANKRD36 Gene

GeneCards Summary for ANKRD36 Gene

ANKRD36 (Ankyrin Repeat Domain 36) is a Protein Coding gene. An important paralog of this gene is ANKRD18A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD36 Gene

Genomics for ANKRD36 Gene

Regulatory Elements for ANKRD36 Gene

Promoters for ANKRD36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD36 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD36 Gene

Chromosome:
2
Start:
97,113,186 bp from pter
End:
97,264,521 bp from pter
Size:
151,336 bases
Orientation:
Plus strand

Genomic View for ANKRD36 Gene

Genes around ANKRD36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD36 Gene

Proteins for ANKRD36 Gene

  • Protein details for ANKRD36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6QL64-AN36A_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 36A
    Protein Accession:
    A6QL64
    Secondary Accessions:
    • B4E3I8
    • Q6UX02
    • Q86X62
    • Q9HCD1

    Protein attributes for ANKRD36 Gene

    Size:
    1941 amino acids
    Molecular mass:
    217465 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ88934.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAQ88934.1; Type=Frameshift; Positions=5; Evidence={ECO:0000305}; Sequence=BAB13467.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD36 Gene

neXtProt entry for ANKRD36 Gene

Proteomics data for ANKRD36 Gene at MOPED

Post-translational modifications for ANKRD36 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD36 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD36 Gene

Domains & Families for ANKRD36 Gene

Gene Families for ANKRD36 Gene

Protein Domains for ANKRD36 Gene

Suggested Antigen Peptide Sequences for ANKRD36 Gene

Graphical View of Domain Structure for InterPro Entry

A6QL64

UniProtKB/Swiss-Prot:

AN36A_HUMAN :
  • Belongs to the ANKRD36 family.
  • Contains 6 ANK repeats.
Family:
  • Belongs to the ANKRD36 family.
Similarity:
  • Contains 6 ANK repeats.
genes like me logo Genes that share domains with ANKRD36: view

Function for ANKRD36 Gene

Phenotypes for ANKRD36 Gene

genes like me logo Genes that share phenotypes with ANKRD36: view

Animal Model Products

CRISPR Products

miRNA for ANKRD36 Gene

miRTarBase miRNAs that target ANKRD36

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD36 Gene

Localization for ANKRD36 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD36 Gene COMPARTMENTS Subcellular localization image for ANKRD36 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD36 Gene

Pathways & Interactions for ANKRD36 Gene

SuperPathways for ANKRD36 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD36 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD36 Gene

Drugs & Compounds for ANKRD36 Gene

No Compound Related Data Available

Transcripts for ANKRD36 Gene

Unigene Clusters for ANKRD36 Gene

Ankyrin repeat domain 36:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD36 Gene

No ASD Table

Relevant External Links for ANKRD36 Gene

GeneLoc Exon Structure for
ANKRD36
ECgene alternative splicing isoforms for
ANKRD36

Expression for ANKRD36 Gene

mRNA expression in normal human tissues for ANKRD36 Gene

Protein differential expression in normal tissues from HIPED for ANKRD36 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD36 Gene



SOURCE GeneReport for Unigene cluster for ANKRD36 Gene Hs.541894

genes like me logo Genes that share expression patterns with ANKRD36: view

Protein tissue co-expression partners for ANKRD36 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD36 Gene

Orthologs for ANKRD36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD36 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 41 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 19 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 18 (a)
ManyToMany
-- 36
  • 21 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 21 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm1758 36
  • 33 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 16 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ANKRD36 36
  • 96 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 22 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 35 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 36
  • 13 (a)
OneToMany
Species with no ortholog for ANKRD36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD36 Gene

ENSEMBL:
Gene Tree for ANKRD36 (if available)
TreeFam:
Gene Tree for ANKRD36 (if available)

Paralogs for ANKRD36 Gene

Pseudogenes.org Pseudogenes for ANKRD36 Gene

genes like me logo Genes that share paralogs with ANKRD36: view

Variants for ANKRD36 Gene

Sequence variations from dbSNP and Humsavar for ANKRD36 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1047675 -- 97,241,336(+) GATAA(C/T)CACTG nc-transcript-variant, downstream-variant-500B, reference, synonymous-codon
rs1057578 -- 97,235,518(+) ttgct(A/G)attta intron-variant, utr-variant-3-prime
rs1358633 -- 97,167,624(+) TTTTC(A/C/G)TTTTT intron-variant
rs1809114 -- 97,114,296(+) tgagg(G/T)gtggg intron-variant
rs1636143 -- 97,167,657(+) ATATA(C/T)ATGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD36 Gene

Variant ID Type Subtype PubMed ID
dgv650e201 CNV Deletion 23290073
esv5003 CNV Complex 18987735
essv10696 CNV CNV 17122850
esv718 CNV CNV 17122850
dgv1229e1 CNV Complex 17122850
nsv834308 CNV Gain 17160897
essv17393 CNV CNV 17122850
nsv470477 CNV Loss 18288195
nsv874683 CNV Loss 21882294
nsv874684 CNV Gain 21882294
dgv4250n71 CNV Loss 21882294
nsv874687 CNV Loss 21882294
nsv517613 CNV Gain+Loss 19592680
nsv818074 CNV Loss 17921354
nsv522486 CNV Gain 19592680
esv32762 CNV Loss 17666407
nsv820355 CNV Duplication 20802225
esv27016 CNV Gain+Loss 19812545
nsv10096 CNV Gain+Loss 18304495
esv2660796 CNV Deletion 23128226
esv2720415 CNV Deletion 23290073
esv2675758 CNV Deletion 23128226
nsv213262 CNV Loss 16902084
nsv441770 CNV CNV 18776908
nsv874695 CNV Loss 21882294
esv2720416 CNV Deletion 23290073
nsv511798 CNV Loss 21212237
dgv720e199 CNV Deletion 23128226
esv2671652 CNV Deletion 23128226
esv5691 CNV Loss 19470904
nsv511164 CNV Loss 21212237
nsv10097 CNV Gain+Loss 18304495
esv992727 CNV Gain 20482838
nsv821502 CNV Duplication 20802225
esv2720418 CNV Deletion 23290073
esv5642 CNV Loss 19470904
nsv7323 OTHER Inversion 18451855
nsv436306 CNV Deletion 17901297
esv2720419 CNV Deletion 23290073
esv2598149 CNV Deletion 19546169
esv2720420 CNV Deletion 23290073
esv2720421 CNV Deletion 23290073
esv2661280 CNV Deletion 23128226
essv18990 CNV CNV 17122850
esv25103 CNV Gain 19812545

Variation tolerance for ANKRD36 Gene

Gene Damage Index Score: 13.00; 94.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD36 Gene

HapMap Linkage Disequilibrium report
ANKRD36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD36 Gene

Disorders for ANKRD36 Gene

Relevant External Links for ANKRD36

Genetic Association Database (GAD)
ANKRD36
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD36

No disorders were found for ANKRD36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD36 Gene

Publications for ANKRD36 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 67
  2. Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. (PMID: 26460568) Johnson-Kerner B.L. … Wichterle H. (PLoS ONE 2015) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3

Products for ANKRD36 Gene

Sources for ANKRD36 Gene

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