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Aliases for ANKRD36 Gene

Aliases for ANKRD36 Gene

  • Ankyrin Repeat Domain 36 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 36A 3
  • Ankyrin Repeat Domain-Containing Protein 36 3
  • Ankyrin-Related 3
  • ANKRD36A 4
  • KIAA1641 4
  • UNQ2430 3

External Ids for ANKRD36 Gene

Previous GeneCards Identifiers for ANKRD36 Gene

  • GC02P097202
  • GC02P097782
  • GC02P091738

Summaries for ANKRD36 Gene

GeneCards Summary for ANKRD36 Gene

ANKRD36 (Ankyrin Repeat Domain 36) is a Protein Coding gene. An important paralog of this gene is ANKRD36C.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD36 Gene

Genomics for ANKRD36 Gene

Regulatory Elements for ANKRD36 Gene

Enhancers for ANKRD36 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G097644 1.3 ENCODE dbSUPER 5.5 +533.0 532973 2.8 HDGF PKNOX1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF766 KLF13 ACTR1B UNC50 LOC100506123 ANKRD36 LINC01125 PIR38581 COX5B
GH02G097949 1.1 Ensembl ENCODE dbSUPER 4.6 +837.8 837767 2.0 CAVIN1 CEBPB RFX5 JUND EED NFYB MAFK EGR2 RNU7-96P TMEM131 VWA3B ACTR1B ANKRD36 LINC01125
GH02G096806 1.1 FANTOM5 Ensembl ENCODE 4 -306.3 -306323 1.4 ARID3A NRF1 ZBTB33 MLLT1 ZNF652 ZNF7 LMAN2L CNNM4 SNRNP200 ANKRD36 CNNM3 ARID5A KANSL3 PIR40637 MIR3127
GH02G097979 0.5 dbSUPER 4.6 +867.6 867579 2.7 RAD51 POLR2A HLF CEBPB RNU7-96P ZAP70 VWA3B LINC01125 ANKRD36B ANKRD36 TMEM131
GH02G097111 1.1 ENCODE 0.7 -0.1 -120 2.3 PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207 ACTR1B FAHD2B SEMA4C ANKRD36 RN7SL313P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKRD36 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000120365 415 2800 PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 SP3

Genomic Location for ANKRD36 Gene

Chromosome:
2
Start:
97,113,186 bp from pter
End:
97,264,521 bp from pter
Size:
151,336 bases
Orientation:
Plus strand

Genomic View for ANKRD36 Gene

Genes around ANKRD36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD36 Gene

Proteins for ANKRD36 Gene

  • Protein details for ANKRD36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6QL64-AN36A_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 36A
    Protein Accession:
    A6QL64
    Secondary Accessions:
    • B4E3I8
    • Q6UX02
    • Q86X62
    • Q9HCD1

    Protein attributes for ANKRD36 Gene

    Size:
    1941 amino acids
    Molecular mass:
    217465 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ88934.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAQ88934.1; Type=Frameshift; Positions=5; Evidence={ECO:0000305}; Sequence=BAB13467.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD36 Gene

neXtProt entry for ANKRD36 Gene

Post-translational modifications for ANKRD36 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKRD36 Gene

Domains & Families for ANKRD36 Gene

Gene Families for ANKRD36 Gene

Protein Domains for ANKRD36 Gene

Suggested Antigen Peptide Sequences for ANKRD36 Gene

Graphical View of Domain Structure for InterPro Entry

A6QL64

UniProtKB/Swiss-Prot:

AN36A_HUMAN :
  • Belongs to the ANKRD36 family.
Family:
  • Belongs to the ANKRD36 family.
genes like me logo Genes that share domains with ANKRD36: view

Function for ANKRD36 Gene

Phenotypes for ANKRD36 Gene

genes like me logo Genes that share phenotypes with ANKRD36: view

Animal Model Products

CRISPR Products

miRNA for ANKRD36 Gene

miRTarBase miRNAs that target ANKRD36

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD36 Gene

Localization for ANKRD36 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD36 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD36 Gene

Pathways & Interactions for ANKRD36 Gene

SuperPathways for ANKRD36 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD36 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD36 Gene

Drugs & Compounds for ANKRD36 Gene

No Compound Related Data Available

Transcripts for ANKRD36 Gene

Unigene Clusters for ANKRD36 Gene

Ankyrin repeat domain 36:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD36 Gene

No ASD Table

Relevant External Links for ANKRD36 Gene

GeneLoc Exon Structure for
ANKRD36
ECgene alternative splicing isoforms for
ANKRD36

Expression for ANKRD36 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD36 Gene

Protein differential expression in normal tissues from HIPED for ANKRD36 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD36 Gene



Protein tissue co-expression partners for ANKRD36 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ANKRD36 Gene:

ANKRD36

SOURCE GeneReport for Unigene cluster for ANKRD36 Gene:

Hs.541894

Evidence on tissue expression from TISSUES for ANKRD36 Gene

  • Nervous system(2.1)
genes like me logo Genes that share expression patterns with ANKRD36: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD36 Gene

Orthologs for ANKRD36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD36 35
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 35
  • 42 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 31 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
-- 35
  • 21 (a)
ManyToMany
-- 35
  • 19 (a)
ManyToMany
-- 35
  • 18 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 41 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm1758 35
  • 33 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 21 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 16 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 22 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 35 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 35
  • 13 (a)
OneToMany
Species where no ortholog for ANKRD36 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD36 Gene

ENSEMBL:
Gene Tree for ANKRD36 (if available)
TreeFam:
Gene Tree for ANKRD36 (if available)

Paralogs for ANKRD36 Gene

Pseudogenes.org Pseudogenes for ANKRD36 Gene

genes like me logo Genes that share paralogs with ANKRD36: view

Variants for ANKRD36 Gene

Sequence variations from dbSNP and Humsavar for ANKRD36 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000113457 -- 97,187,442(+) TCCAG(A/T)TAGAA intron-variant
rs1000113821 -- 97,141,131(+) CCCCT(A/G)TGGTA intron-variant
rs1000140911 -- 97,122,073(+) TCAAT(C/T)GTGTC intron-variant
rs1000159129 -- 97,230,967(+) TGAAC(C/T)GCGAA intron-variant
rs1000178453 -- 97,165,768(+) AAACT(C/T)TAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD36 Gene

Variant ID Type Subtype PubMed ID
dgv1142e212 CNV loss 25503493
dgv1143e212 CNV loss 25503493
dgv1144e212 CNV loss 25503493
dgv1145e212 CNV gain 25503493
dgv1146e212 CNV loss 25503493
dgv1974n106 CNV deletion 24896259
dgv2199e59 CNV duplication 20981092
dgv4010n100 CNV gain 25217958
dgv4011n100 CNV loss 25217958
dgv4012n100 CNV loss 25217958
dgv4013n100 CNV gain+loss 25217958
dgv4014n100 CNV gain 25217958
dgv4015n100 CNV gain+loss 25217958
dgv4016n100 CNV loss 25217958
dgv4017n100 CNV gain 25217958
dgv4018n100 CNV gain 25217958
dgv4019n100 CNV gain 25217958
dgv4020n100 CNV gain 25217958
dgv4021n100 CNV gain 25217958
dgv4022n100 CNV gain 25217958
dgv4023n100 CNV loss 25217958
dgv4024n100 CNV gain 25217958
dgv4025n100 CNV gain 25217958
dgv607e201 CNV deletion 23290073
dgv6971n54 CNV gain 21841781
dgv6972n54 CNV loss 21841781
dgv720e199 CNV deletion 23128226
esv25103 CNV gain 19812545
esv2598149 CNV deletion 19546169
esv2660796 CNV deletion 23128226
esv2661280 CNV deletion 23128226
esv2671652 CNV deletion 23128226
esv2675758 CNV deletion 23128226
esv27016 CNV gain+loss 19812545
esv2720415 CNV deletion 23290073
esv2720416 CNV deletion 23290073
esv2720418 CNV deletion 23290073
esv2720419 CNV deletion 23290073
esv2720420 CNV deletion 23290073
esv2720421 CNV deletion 23290073
esv2759077 CNV gain+loss 17122850
esv2760609 CNV gain+loss 21179565
esv2763630 CNV gain+loss 21179565
esv3119345 CNV duplication 24192839
esv32762 CNV loss 17666407
esv3357691 CNV duplication 20981092
esv3382408 CNV duplication 20981092
esv3394465 CNV duplication 20981092
esv3413527 CNV duplication 20981092
esv3418578 CNV duplication 20981092
esv3425717 CNV duplication 20981092
esv3559821 CNV deletion 23714750
esv3559822 CNV deletion 23714750
esv3575281 CNV gain 25503493
esv3583944 CNV loss 25503493
esv3583955 CNV loss 25503493
esv3583964 CNV loss 25503493
esv3591697 CNV loss 21293372
esv3591698 CNV gain 21293372
esv3591699 CNV loss 21293372
esv3591701 CNV loss 21293372
esv3591702 CNV loss 21293372
esv3591704 CNV loss 21293372
esv3591706 CNV loss 21293372
esv3591707 CNV loss 21293372
esv3892959 CNV loss 25118596
esv3892971 CNV loss 25118596
esv5003 OTHER complex 18987735
esv5642 CNV loss 19470904
esv5691 CNV loss 19470904
esv992727 CNV gain 20482838
nsv1000203 CNV gain+loss 25217958
nsv1007387 CNV gain+loss 25217958
nsv1008637 CNV loss 25217958
nsv10096 CNV gain+loss 18304495
nsv10097 CNV gain+loss 18304495
nsv1010807 CNV gain 25217958
nsv1011763 CNV gain 25217958
nsv1071246 CNV deletion 25765185
nsv1072009 CNV deletion 25765185
nsv1076490 CNV duplication 25765185
nsv1077364 CNV duplication 25765185
nsv1077365 CNV duplication 25765185
nsv1077887 CNV duplication 25765185
nsv1078465 CNV duplication 25765185
nsv1110349 CNV duplication 24896259
nsv1112767 CNV deletion 24896259
nsv1118640 CNV duplication 24896259
nsv1118869 CNV deletion 24896259
nsv1123359 CNV deletion 24896259
nsv1125311 OTHER inversion 24896259
nsv1128803 CNV duplication 24896259
nsv1131493 CNV deletion 24896259
nsv1132498 CNV duplication 24896259
nsv1135873 CNV deletion 24896259
nsv1136388 CNV deletion 24896259
nsv1138820 CNV deletion 24896259
nsv1139723 CNV duplication 24896259
nsv1141354 CNV duplication 24896259
nsv1146869 CNV duplication 26484159
nsv1148786 OTHER inversion 26484159
nsv1150248 CNV duplication 26484159
nsv1151122 CNV duplication 26484159
nsv1160826 CNV duplication 26073780
nsv1160827 CNV duplication 26073780
nsv1160828 CNV duplication 26073780
nsv213262 CNV deletion 16902084
nsv436306 CNV deletion 17901297
nsv441770 CNV gain+loss 18776908
nsv470477 CNV loss 18288195
nsv511164 CNV loss 21212237
nsv511798 CNV loss 21212237
nsv517613 CNV gain+loss 19592680
nsv522486 CNV gain 19592680
nsv582500 CNV loss 21841781
nsv582502 CNV gain 21841781
nsv7323 OTHER inversion 18451855
nsv818074 CNV loss 17921354
nsv820355 CNV duplication 20802225
nsv821502 CNV duplication 20802225
nsv834308 CNV gain 17160897
nsv953482 CNV duplication 24416366
nsv953483 CNV duplication 24416366
nsv953484 CNV deletion 24416366
nsv954758 CNV deletion 24416366
nsv954787 CNV deletion 24416366
nsv979067 CNV duplication 23825009
nsv997395 CNV loss 25217958
nsv998307 CNV loss 25217958

Variation tolerance for ANKRD36 Gene

Gene Damage Index Score: 13.00; 94.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD36 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD36 Gene

Disorders for ANKRD36 Gene

Relevant External Links for ANKRD36

Genetic Association Database (GAD)
ANKRD36
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD36

No disorders were found for ANKRD36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD36 Gene

Publications for ANKRD36 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 64
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 3 4 64

Products for ANKRD36 Gene

Sources for ANKRD36 Gene

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