ANKRD34A Gene
protein-coding GIFtS: 39
GCID: GC01P145470
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ankyrin repeat domain 34A(Previous name: ankyrin repeat domain 34 )
(Previous symbol: ANKRD34)
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Aliases
for ANKRD34A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat Domain 34A1 2 | | ANKRD341 2 3 | | Ankyrin Repeat Domain 341 2 | | Ankyrin Repeat Domain-Containing Protein 34A2 |
Export aliases for ANKRD34A gene to outside databasesPrevious GC identifers: GC01P144182 GC01P119434 |
Summaries
for ANKRD34A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ANKRD34A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167185.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKRD34A gene promoter:
Spz1 NF-1 Sp1 Olf-1 RelA LCR-F1 C/EBPalpha CHOP-10 HOXA5
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKRD34A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD34A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.1 Ensembl cytogenetic band: 1q21.1 HGNC cytogenetic band: 1q21.1ANKRD34A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P145470: view genomic region
(about GC identifiers)
Start:
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145,470,508 bp from pter |
End:
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145,475,647 bp from pter |
Size:
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5,140 bases |
Orientation:
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plus strand |
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Proteins
for ANKRD34A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AN34A_HUMAN, Q69YU3 (See
protein sequence)Recommended Name: Ankyrin repeat domain-containing protein 34A Size: 496 amino acids; 52636 Da
Secondary accessions: B3KSU3Explore the universe of human proteins at neXtProt for ANKRD34A: NX_Q69YU3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q69YU3
ANKRD34A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001034977.1
ENSEMBL proteins: ENSP00000314103
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IDA | -- |
ANKRD34A for ontologies About GeneDecksing
ANKRD34A Antibody Products:
Assay Products for ANKRD34A: |
Protein
Domains /
Families
for ANKRD34A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKRD34A for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q69YU3ProtoNet protein and cluster: Q69YU3 UniProtKB/Swiss-Prot: AN34A_HUMAN, Q69YU3Similarity: Belongs to the ANKRD34 familySimilarity: Contains 4 ANK repeats |
Function
for ANKRD34A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ANKRD34A | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD34A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD34A |
|
Pathways & Interactions
for ANKRD34A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD34A
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ANKRD34A (Q69YU33 ENSP000003141034) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ANKRD34A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKRD34A
Search CenterWatch for drugs/clinical trials and news about ANKRD34A / AN34A
|
Transcripts
for ANKRD34A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKRD34A gene: NM_001039888.2 Unigene Cluster for ANKRD34A: Ankyrin repeat domain 34A Hs.620591 [show with all ESTs]Unigene Representative Sequence: NM_0010398881 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000323397(uc001enq.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ANKRD34A (NM_001039888) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKRD34A | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD34A |
Additional cDNA sequence: AK094282.1 AK128050.1 AL359622.1 4 DOTS entries: DT.97839527 DT.95110159 DT.121458626 DT.91941242
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD34A About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
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| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for ANKRD34A
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Expression
for ANKRD34A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKRD34A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCTCTAAGC
About this image
See ANKRD34A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKRD34A
SOURCE GeneReport for Unigene cluster: Hs.620591
SABiosciences Custom PCR Arrays for ANKRD34A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKRD34A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANKRD34A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD34A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD34A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD34A |
Orthologs
for ANKRD34A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANKRD34A gene from 1/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC7980971 |
ankyrin repeat domain-containing protein 34A-like |
61.06(n)
62.07(a) |
|
798097 XM_003200247.1 XP_003200295.1 |
ENSEMBL Gene Tree for ANKRD34A (if available)
TreeFam Gene Tree for ANKRD34A (if available) |
Paralogs
for ANKRD34A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANKRD34A gene
- ANKRD34C2 ANKRD34B2
2 SIMAP similar genes for ANKRD34A using alignment to 1 protein entry: AN34A_HUMAN:ANKRD34C ANKRD34B
ANKRD34A for paralogs About GeneDecksing
|
Genomic Variants
for ANKRD34A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANKRD34A (145470508 - 145475647 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ANKRD34A
6 CNVs: 2324 6781 5199 30420 53561 3310 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD34A |
|
Disorders
/ Diseases
for ANKRD34A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ANKRD34A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKRD34A gene integrated from 9 sources:
(articles sorted by number of sources associating them with ANKRD34A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
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External Searches for ANKRD34A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ANKRD34A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKRD34A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANKRD34A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKRD34A | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ANKRD34A gene:
Search GeneIP for patents involving ANKRD34A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKRD34A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ANKRD34A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANKRD34A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKRD34A | | | OriGene Protein Over-expression Lysate for ANKRD34A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANKRD34A | | OriGene 3'-UTR Clone for ANKRD34A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD34A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ANKRD34A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | ANKRD34A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD34A |
|  |  |  | | | | Search ThermoFisher Antibodies for ANKRD34A |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD34A |
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