Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ANKRD33B Gene

Aliases for ANKRD33B Gene

  • Ankyrin Repeat Domain 33B 2 3 5

External Ids for ANKRD33B Gene

Previous GeneCards Identifiers for ANKRD33B Gene

  • GC05P010616

Summaries for ANKRD33B Gene

GeneCards Summary for ANKRD33B Gene

ANKRD33B (Ankyrin Repeat Domain 33B) is a Protein Coding gene. An important paralog of this gene is ANKRD33.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD33B Gene

Genomics for ANKRD33B Gene

Regulatory Elements for ANKRD33B Gene

Promoters for ANKRD33B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD33B on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD33B Gene

10,564,323 bp from pter
10,657,816 bp from pter
93,494 bases
Plus strand

Genomic View for ANKRD33B Gene

Genes around ANKRD33B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD33B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD33B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD33B Gene

Proteins for ANKRD33B Gene

  • Protein details for ANKRD33B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 33B
    Protein Accession:

    Protein attributes for ANKRD33B Gene

    494 amino acids
    Molecular mass:
    53975 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD33B Gene

Proteomics data for ANKRD33B Gene at MOPED

Post-translational modifications for ANKRD33B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD33B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD33B Gene

Domains & Families for ANKRD33B Gene

Gene Families for ANKRD33B Gene

Protein Domains for ANKRD33B Gene

Suggested Antigen Peptide Sequences for ANKRD33B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 ANK repeats.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with ANKRD33B: view

Function for ANKRD33B Gene

Phenotypes for ANKRD33B Gene

GenomeRNAi human phenotypes for ANKRD33B:
genes like me logo Genes that share phenotypes with ANKRD33B: view

Animal Model Products

CRISPR Products

miRNA for ANKRD33B Gene

miRTarBase miRNAs that target ANKRD33B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD33B Gene

Localization for ANKRD33B Gene

Subcellular locations from

Jensen Localization Image for ANKRD33B Gene COMPARTMENTS Subcellular localization image for ANKRD33B gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD33B Gene

Pathways & Interactions for ANKRD33B Gene

SuperPathways for ANKRD33B Gene

No Data Available

Interacting Proteins for ANKRD33B Gene

Gene Ontology (GO) - Biological Process for ANKRD33B Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD33B Gene

Drugs & Compounds for ANKRD33B Gene

No Compound Related Data Available

Transcripts for ANKRD33B Gene

mRNA/cDNA for ANKRD33B Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD33B Gene

Ankyrin repeat domain 33B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD33B Gene

No ASD Table

Relevant External Links for ANKRD33B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD33B Gene

mRNA expression in normal human tissues for ANKRD33B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ANKRD33B Gene

This gene is overexpressed in Heart (51.5) and Retina (17.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKRD33B Gene

SOURCE GeneReport for Unigene cluster for ANKRD33B Gene Hs.26039

genes like me logo Genes that share expression patterns with ANKRD33B: view

Protein tissue co-expression partners for ANKRD33B Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD33B Gene

Orthologs for ANKRD33B Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD33B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD33B 35
  • 83.67 (n)
  • 79.51 (a)
  • 78 (a)
(Canis familiaris)
Mammalia ANKRD33B 35
  • 83.92 (n)
  • 79.71 (a)
  • 79 (a)
(Mus musculus)
Mammalia Ankrd33b 35
  • 78.28 (n)
  • 77.11 (a)
Ankrd33b 16
Ankrd33b 36
  • 77 (a)
(Pan troglodytes)
Mammalia ANKRD33B 35
  • 99.19 (n)
  • 99.6 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Ankrd33b 35
  • 77.48 (n)
  • 78.38 (a)
(Monodelphis domestica)
Mammalia ANKRD33B 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD33B 36
  • 58 (a)
(Gallus gallus)
Aves ANKRD33B 35
  • 63.69 (n)
  • 60.35 (a)
  • 54 (a)
(Anolis carolinensis)
Reptilia ANKRD33B 36
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494504 35
  • 54.16 (n)
  • 55.21 (a)
(Danio rerio)
Actinopterygii ankrd33ba 35
  • 58.29 (n)
  • 51.44 (a)
ankrd33ba 36
  • 46 (a)
ankrd33bb 36
  • 47 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
Species with no ortholog for ANKRD33B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD33B Gene

Gene Tree for ANKRD33B (if available)
Gene Tree for ANKRD33B (if available)

Paralogs for ANKRD33B Gene

Paralogs for ANKRD33B Gene

(1) SIMAP similar genes for ANKRD33B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ANKRD33B: view

Variants for ANKRD33B Gene

Sequence variations from dbSNP and Humsavar for ANKRD33B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs728848 -- 10,622,653(-) AATTT(A/T)AAAAA intron-variant
rs1026914 -- 10,630,547(-) GATTT(C/T)AGTGA intron-variant
rs814576 -- 10,564,734(+) ACCCT(C/T)CTGCG upstream-variant-2KB, reference, synonymous-codon
rs814577 -- 10,566,089(-) ACGTG(C/G/T)TGTGG intron-variant
rs814578 -- 10,567,399(+) GAATC(C/T)GGCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD33B Gene

Variant ID Type Subtype PubMed ID
nsv880520 CNV Gain 21882294
esv27558 CNV Loss 19812545
nsv513220 CNV Loss 21212237
esv2570309 CNV Deletion 19546169
esv2302807 CNV Deletion 18987734
esv5923 CNV Loss 19470904
esv2729744 CNV Deletion 23290073
nsv329316 CNV Loss 16902084
nsv507230 CNV Insertion 20534489
esv268690 CNV Insertion 20981092
nsv511306 CNV Loss 21212237
esv2429278 CNV Deletion 19546169
esv29091 CNV Gain+Loss 19812545
esv5335 CNV Deletion 18987735
nsv513221 CNV Loss 21212237
esv1001828 CNV Gain 20482838
esv2729745 CNV Deletion 23290073
nsv329565 CNV Loss 16902084
dgv978e201 CNV Deletion 23290073
esv25753 CNV Loss 19812545

Variation tolerance for ANKRD33B Gene

Gene Damage Index Score: 3.38; 54.06% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD33B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD33B Gene

Disorders for ANKRD33B Gene

Relevant External Links for ANKRD33B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD33B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD33B Gene

Publications for ANKRD33B Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4 67
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ANKRD33B Gene

Sources for ANKRD33B Gene

Back to Top