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Aliases for ANKRD31 Gene

Aliases for ANKRD31 Gene

  • Ankyrin Repeat Domain 31 2 3 5

External Ids for ANKRD31 Gene

Previous GeneCards Identifiers for ANKRD31 Gene

  • GC05M074460
  • GC05M074399
  • GC05M074477
  • GC05M074364
  • GC05M069568

Summaries for ANKRD31 Gene

GeneCards Summary for ANKRD31 Gene

ANKRD31 (Ankyrin Repeat Domain 31) is a Protein Coding gene. An important paralog of this gene is BCORL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD31 Gene

Genomics for ANKRD31 Gene

Regulatory Elements for ANKRD31 Gene

Promoters for ANKRD31 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD31 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD31 Gene

Chromosome:
5
Start:
75,068,275 bp from pter
End:
75,236,887 bp from pter
Size:
168,613 bases
Orientation:
Minus strand

Genomic View for ANKRD31 Gene

Genes around ANKRD31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD31 Gene

Proteins for ANKRD31 Gene

  • Protein details for ANKRD31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7Z5-ANR31_HUMAN
    Recommended name:
    Putative ankyrin repeat domain-containing protein 31
    Protein Accession:
    Q8N7Z5

    Protein attributes for ANKRD31 Gene

    Size:
    1873 amino acids
    Molecular mass:
    210816 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD31 Gene

Proteomics data for ANKRD31 Gene at MOPED

Post-translational modifications for ANKRD31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD31 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD31 Gene

Domains & Families for ANKRD31 Gene

Gene Families for ANKRD31 Gene

Protein Domains for ANKRD31 Gene

Suggested Antigen Peptide Sequences for ANKRD31 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N7Z5

UniProtKB/Swiss-Prot:

ANR31_HUMAN :
  • Contains 6 ANK repeats.
Similarity:
  • Contains 6 ANK repeats.
genes like me logo Genes that share domains with ANKRD31: view

Function for ANKRD31 Gene

genes like me logo Genes that share phenotypes with ANKRD31: view

Animal Model Products

miRNA for ANKRD31 Gene

miRTarBase miRNAs that target ANKRD31

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD31 Gene

Localization for ANKRD31 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD31 Gene COMPARTMENTS Subcellular localization image for ANKRD31 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD31 Gene

Pathways & Interactions for ANKRD31 Gene

SuperPathways for ANKRD31 Gene

No Data Available

Interacting Proteins for ANKRD31 Gene

Gene Ontology (GO) - Biological Process for ANKRD31 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD31 Gene

Drugs & Compounds for ANKRD31 Gene

No Compound Related Data Available

Transcripts for ANKRD31 Gene

mRNA/cDNA for ANKRD31 Gene

(7) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD31 Gene

Ankyrin repeat domain 31:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD31 Gene

No ASD Table

Relevant External Links for ANKRD31 Gene

GeneLoc Exon Structure for
ANKRD31
ECgene alternative splicing isoforms for
ANKRD31

Expression for ANKRD31 Gene

mRNA expression in normal human tissues for ANKRD31 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD31 Gene

This gene is overexpressed in Testis (x19.9).

Protein differential expression in normal tissues from HIPED for ANKRD31 Gene

This gene is overexpressed in Platelet (30.2), Gallbladder (16.9), Blymphocyte (14.2), and Kidney (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD31 Gene



SOURCE GeneReport for Unigene cluster for ANKRD31 Gene Hs.482533

genes like me logo Genes that share expression patterns with ANKRD31: view

Protein tissue co-expression partners for ANKRD31 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKRD31 Gene

Orthologs for ANKRD31 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ANKRD31 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD31 35
  • 99.25 (n)
  • 98.56 (a)
ANKRD31 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD31 36
  • 69 (a)
OneToOne
ANKRD31 35
  • 80.59 (n)
  • 67.14 (a)
dog
(Canis familiaris)
Mammalia ANKRD31 35
  • 82.49 (n)
  • 69.56 (a)
ANKRD31 36
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd31 16
Ankrd31 35
  • 73.1 (n)
  • 56.09 (a)
oppossum
(Monodelphis domestica)
Mammalia ANKRD31 36
  • 40 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD31 36
  • 22 (a)
OneToOne
chicken
(Gallus gallus)
Aves ANKRD31 36
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD31 36
  • 49 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ankrd31 36
  • 25 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HOS4 36
  • 12 (a)
OneToMany
Species with no ortholog for ANKRD31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD31 Gene

ENSEMBL:
Gene Tree for ANKRD31 (if available)
TreeFam:
Gene Tree for ANKRD31 (if available)

Paralogs for ANKRD31 Gene

Paralogs for ANKRD31 Gene

(4) SIMAP similar genes for ANKRD31 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ANKRD31: view

Variants for ANKRD31 Gene

Sequence variations from dbSNP and Humsavar for ANKRD31 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1422698 - 75,147,307(-) CTCTT(A/G)ACCAG reference, missense
rs6893216 - 75,147,139(+) TATTC(C/T)CCTGG reference, missense
rs961098 - 75,104,561(-) CAGGA(C/G)CTTTC reference, missense
rs4489037 - 75,084,346(+) CATAC(C/T)TTAAA reference, missense
rs256467 -- 75,134,827(+) atcaa(A/G)tgggc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD31 Gene

Variant ID Type Subtype PubMed ID
nsv882189 CNV Loss 21882294
nsv4879 CNV Insertion 18451855
nsv509073 CNV Insertion 20534489
dgv1812e1 CNV Complex 17122850
dgv6182n71 CNV Loss 21882294
nsv4880 CNV Insertion 18451855
nsv327808 CNV Loss 16902084

Variation tolerance for ANKRD31 Gene

Gene Damage Index Score: 10.83; 91.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD31 Gene

HapMap Linkage Disequilibrium report
ANKRD31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD31 Gene

Disorders for ANKRD31 Gene

Relevant External Links for ANKRD31

Genetic Association Database (GAD)
ANKRD31
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD31

No disorders were found for ANKRD31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD31 Gene

Publications for ANKRD31 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). (PMID: 22952603) Hart A.B. … Palmer A.A. (PLoS ONE 2012) 3

Products for ANKRD31 Gene

Sources for ANKRD31 Gene

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