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Aliases for ANKRD30B Gene

Aliases for ANKRD30B Gene

  • Ankyrin Repeat Domain 30B 2 3
  • Serologically Defined Breast Cancer Antigen NY-BR-1.1 3 4
  • Ankyrin Repeat Domain-Containing Protein 30B 3
  • Breast Cancer Antigen NY-BR-1.1 3
  • NY-BR-1.1 3

External Ids for ANKRD30B Gene

Summaries for ANKRD30B Gene

GeneCards Summary for ANKRD30B Gene

ANKRD30B (Ankyrin Repeat Domain 30B) is a Protein Coding gene. Diseases associated with ANKRD30B include breast cancer. An important paralog of this gene is POTEJ.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD30B Gene

Genomics for ANKRD30B Gene

Genomic Location for ANKRD30B Gene

Start:
14,728,272 bp from pter
End:
14,852,738 bp from pter
Size:
124,467 bases
Orientation:
Plus strand

Genomic View for ANKRD30B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD30B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD30B Gene

Regulatory Elements for ANKRD30B Gene

Proteins for ANKRD30B Gene

  • Protein details for ANKRD30B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BXX2-AN30B_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 30B
    Protein Accession:
    Q9BXX2
    Secondary Accessions:
    • B4DGP1
    • F8WAG3
    • Q4G175

    Protein attributes for ANKRD30B Gene

    Size:
    1392 amino acids
    Molecular mass:
    158049 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK27326.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAK27326.1; Type=Frameshift; Positions=120; Evidence={ECO:0000305}; Sequence=BAG57852.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD30B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD30B Gene

Proteomics data for ANKRD30B Gene at MOPED

Post-translational modifications for ANKRD30B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD30B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD30B Gene

Domains for ANKRD30B Gene

Gene Families for ANKRD30B Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD30B Gene

UniProtKB/Swiss-Prot:

AN30B_HUMAN
Similarity:
  • Contains 5 ANK repeats.:
    • Q9BXX2
genes like me logo Genes that share domains with ANKRD30B: view

Function for ANKRD30B Gene

Gene Ontology (GO) - Molecular Function for ANKRD30B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD30B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD30B Gene

Localization for ANKRD30B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD30B Gene COMPARTMENTS Subcellular localization image for ANKRD30B gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ANKRD30B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ANKRD30B: view

Pathways for ANKRD30B Gene

SuperPathways for ANKRD30B Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD30B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ANKRD30B: view

No data available for Pathways by source for ANKRD30B Gene

Transcripts for ANKRD30B Gene

mRNA/cDNA for ANKRD30B Gene

(8) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD30B Gene

Ankyrin repeat domain 30B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD30B Gene

No ASD Table

Relevant External Links for ANKRD30B Gene

GeneLoc Exon Structure for
ANKRD30B
ECgene alternative splicing isoforms for
ANKRD30B

Expression for ANKRD30B Gene

mRNA expression in normal human tissues for ANKRD30B Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD30B Gene

This gene is overexpressed in Testis (17.8) and Nerve - Tibial (7.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKRD30B Gene

SOURCE GeneReport for Unigene cluster for ANKRD30B Gene Hs.567889

mRNA Expression by UniProt/SwissProt for ANKRD30B Gene

Q9BXX2-AN30B_HUMAN
Tissue specificity: Expressed in brain, breast and testis.
genes like me logo Genes that share expressions with ANKRD30B: view

Orthologs for ANKRD30B Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD30B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 33 (a)
ManyToMany
-- 37
  • 69 (a)
ManyToMany
ANKRD30B 36
  • 97.44 (n)
  • 95.85 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 40 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 17 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 17 (a)
ManyToMany
-- 37
  • 18 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Ankrd36 37
  • 13 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 29 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 15 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 20 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 36 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 37
  • 10 (a)
OneToMany
Species with no ortholog for ANKRD30B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD30B Gene

ENSEMBL:
Gene Tree for ANKRD30B (if available)
TreeFam:
Gene Tree for ANKRD30B (if available)

Paralogs for ANKRD30B Gene

genes like me logo Genes that share paralogs with ANKRD30B: view

Variants for ANKRD30B Gene

Sequence variations from dbSNP and Humsavar for ANKRD30B Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs1934768 -- 14,846,955(+) ACCAT(G/T)CTGTT intron-variant
rs1934769 -- 14,847,093(+) ATATA(G/T)GTATA intron-variant
rs1970446 -- 14,851,371(+) TTTGA(G/T)TCAAT intron-variant
rs2125205 -- 14,789,983(-) gccat(A/G)ctgcc intron-variant
rs2253874 -- 14,837,242(+) ACAAC(A/G)GGAAC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ANKRD30B Gene

Variant ID Type Subtype PubMed ID
dgv1013e1 CNV Complex 17122850
essv5519 CNV CNV 17122850
nsv909431 CNV Loss 21882294
esv2751771 CNV Loss 17911159
nsv909433 CNV Gain 21882294
esv2421993 CNV Duplication 20811451
nsv9617 CNV Gain+Loss 18304495
dgv1014e1 CNV Complex 17122850
essv24101 CNV CNV 17122850
esv2716842 CNV Deletion 23290073
esv21571 CNV Loss 19812545
nsv2216 CNV Loss 18451855
esv2671401 CNV Deletion 23128226
esv2107318 CNV Deletion 18987734
nsv514862 CNV Complex 21397061
nsv9618 CNV Gain+Loss 18304495
essv21900 CNV CNV 17122850
esv2716843 CNV Deletion 23290073
esv22961 CNV Loss 19812545
nsv498876 CNV Loss 21111241
nsv436247 CNV Deletion 17901297
esv2397925 CNV Deletion 18987734
esv2716844 CNV Deletion 23290073
esv999230 CNV Deletion 20482838
esv2429241 CNV Deletion 19546169
esv1712682 CNV Deletion 17803354
dgv1015e1 CNV Complex 17122850
nsv909434 CNV Gain 21882294
nsv9619 CNV Loss 18304495

Relevant External Links for ANKRD30B Gene

HapMap Linkage Disequilibrium report
ANKRD30B

Disorders for ANKRD30B Gene

(1) MalaCards Diseases for ANKRD30B Gene

Search for ANKRD30B Gene in MalaCards »
genes like me logo Genes that share disorders with ANKRD30B: view

No data available for UniProtKB/Swiss-Prot for ANKRD30B Gene

Publications for ANKRD30B Gene

  1. Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library. (PMID: 11280766) Jaeger D. … Chen Y.-T. (Cancer Res. 2001) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C. … Lander E.S. (Nature 2005) 4

Products for ANKRD30B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ANKRD30B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD30B
    • Block miRNA regulation of ANKRD30B using miScript Target Protectors

    Sources for ANKRD30B Gene

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