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Aliases for ANKRD29 Gene

Aliases for ANKRD29 Gene

  • Ankyrin Repeat Domain 29 2 3 5

External Ids for ANKRD29 Gene

Previous GeneCards Identifiers for ANKRD29 Gene

  • GC18M019432
  • GC18M019434
  • GC18M021178
  • GC18M018035

Summaries for ANKRD29 Gene

GeneCards Summary for ANKRD29 Gene

ANKRD29 (Ankyrin Repeat Domain 29) is a Protein Coding gene. An important paralog of this gene is RNASEL.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD29 Gene

Genomics for ANKRD29 Gene

Regulatory Elements for ANKRD29 Gene

Promoters for ANKRD29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD29 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD29 Gene

Chromosome:
18
Start:
23,598,926 bp from pter
End:
23,662,892 bp from pter
Size:
63,967 bases
Orientation:
Minus strand

Genomic View for ANKRD29 Gene

Genes around ANKRD29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD29 Gene

Proteins for ANKRD29 Gene

  • Protein details for ANKRD29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6D5-ANR29_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 29
    Protein Accession:
    Q8N6D5
    Secondary Accessions:
    • B2R972
    • Q6ZWE8
    • Q96LU9

    Protein attributes for ANKRD29 Gene

    Size:
    301 amino acids
    Molecular mass:
    32442 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC85555.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD29 Gene

Proteomics data for ANKRD29 Gene at MOPED

Post-translational modifications for ANKRD29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD29 Gene

No data available for DME Specific Peptides for ANKRD29 Gene

Domains & Families for ANKRD29 Gene

Gene Families for ANKRD29 Gene

Protein Domains for ANKRD29 Gene

Suggested Antigen Peptide Sequences for ANKRD29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N6D5

UniProtKB/Swiss-Prot:

ANR29_HUMAN :
  • Contains 8 ANK repeats.
Similarity:
  • Contains 8 ANK repeats.
genes like me logo Genes that share domains with ANKRD29: view

Function for ANKRD29 Gene

Phenotypes for ANKRD29 Gene

genes like me logo Genes that share phenotypes with ANKRD29: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD29 Gene

Localization for ANKRD29 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD29 Gene COMPARTMENTS Subcellular localization image for ANKRD29 gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 2
endosome 1
lysosome 1
peroxisome 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD29 Gene

Pathways & Interactions for ANKRD29 Gene

SuperPathways for ANKRD29 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD29 Gene

Drugs & Compounds for ANKRD29 Gene

No Compound Related Data Available

Transcripts for ANKRD29 Gene

Unigene Clusters for ANKRD29 Gene

Ankyrin repeat domain 29:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD29 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d · 12e · 12f ·
SP1: - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - -
SP4: - -
SP5: - - -
SP6: - - - -
SP7:
SP8:
SP9:

ExUns: 12g
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for ANKRD29 Gene

GeneLoc Exon Structure for
ANKRD29
ECgene alternative splicing isoforms for
ANKRD29

Expression for ANKRD29 Gene

mRNA expression in normal human tissues for ANKRD29 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ANKRD29 Gene

This gene is overexpressed in Frontal cortex (27.8), Monocytes (13.4), Spinal cord (11.9), Ovary (9.1), and Retina (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD29 Gene



SOURCE GeneReport for Unigene cluster for ANKRD29 Gene Hs.374774

genes like me logo Genes that share expression patterns with ANKRD29: view

Protein tissue co-expression partners for ANKRD29 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD29 Gene

Orthologs for ANKRD29 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD29 36
  • 100 (a)
OneToOne
ANKRD29 35
  • 99.56 (n)
  • 99.67 (a)
cow
(Bos Taurus)
Mammalia ANKRD29 35
  • 89 (n)
  • 95.92 (a)
ANKRD29 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD29 36
  • 97 (a)
OneToOne
ANKRD29 35
  • 90.18 (n)
  • 97.29 (a)
mouse
(Mus musculus)
Mammalia Ankrd29 16
Ankrd29 36
  • 94 (a)
OneToOne
Ankrd29 35
  • 89.48 (n)
  • 96.01 (a)
oppossum
(Monodelphis domestica)
Mammalia ANKRD29 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 92 (a)
OneToMany
-- 36
  • 86 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Ankrd29 35
  • 88.04 (n)
  • 95.68 (a)
chicken
(Gallus gallus)
Aves ANKRD29 35
  • 78.86 (n)
  • 89.26 (a)
ANKRD29 36
  • 88 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD29 36
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd29 35
  • 73.98 (n)
  • 82.39 (a)
zebrafish
(Danio rerio)
Actinopterygii ankrd29 36
  • 73 (a)
OneToOne
ankrd29 35
  • 68.16 (n)
  • 74.83 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009428 35
  • 54.27 (n)
  • 51.65 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3104 36
  • 43 (a)
OneToOne
CG3104 35
  • 54.2 (n)
  • 49.26 (a)
worm
(Caenorhabditis elegans)
Secernentea R11A8.7 36
  • 4 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3733 36
  • 43 (a)
OneToOne
Species with no ortholog for ANKRD29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD29 Gene

ENSEMBL:
Gene Tree for ANKRD29 (if available)
TreeFam:
Gene Tree for ANKRD29 (if available)

Paralogs for ANKRD29 Gene

Paralogs for ANKRD29 Gene

genes like me logo Genes that share paralogs with ANKRD29: view

Variants for ANKRD29 Gene

Sequence variations from dbSNP and Humsavar for ANKRD29 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs17855552 - 23,634,145(+) TGCCC(C/T)CGTCC nc-transcript-variant, reference, missense
VAR_035610 A breast cancer sample
rs744063 -- 23,620,534(-) TCCCC(C/T)TCCCT intron-variant
rs1711448 -- 23,632,412(+) AATGG(A/G)AGTTA intron-variant
rs1711462 -- 23,624,696(+) GCTAA(A/G/T)ACCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD29 Gene

Variant ID Type Subtype PubMed ID
esv34149 CNV Loss 18971310
nsv509688 CNV Insertion 20534489
nsv131804 CNV Insertion 16902084
nsv131838 CNV Insertion 16902084

Variation tolerance for ANKRD29 Gene

Residual Variation Intolerance Score: 31.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.08; 22.09% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD29 Gene

HapMap Linkage Disequilibrium report
ANKRD29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD29 Gene

Disorders for ANKRD29 Gene

Relevant External Links for ANKRD29

Genetic Association Database (GAD)
ANKRD29
Human Genome Epidemiology (HuGE) Navigator
ANKRD29
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD29

No disorders were found for ANKRD29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD29 Gene

Publications for ANKRD29 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. (PMID: 24256812) Fogh I. … Silani V. (Hum. Mol. Genet. 2014) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ANKRD29 Gene

Sources for ANKRD29 Gene

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