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Aliases for ANKRD24 Gene

Aliases for ANKRD24 Gene

  • Ankyrin Repeat Domain 24 2 3 5
  • KIAA1981 4

External Ids for ANKRD24 Gene

Previous GeneCards Identifiers for ANKRD24 Gene

  • GC19P004134
  • GC19P004135
  • GC19P003946

Summaries for ANKRD24 Gene

GeneCards Summary for ANKRD24 Gene

ANKRD24 (Ankyrin Repeat Domain 24) is a Protein Coding gene. An important paralog of this gene is RAI14.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD24 Gene

Genomics for ANKRD24 Gene

Regulatory Elements for ANKRD24 Gene

Enhancers for ANKRD24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ANKRD24 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for ANKRD24 Gene

4,182,625 bp from pter
4,224,814 bp from pter
42,190 bases
Plus strand

Genomic View for ANKRD24 Gene

Genes around ANKRD24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD24 Gene

Proteins for ANKRD24 Gene

  • Protein details for ANKRD24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 24
    Protein Accession:
    Secondary Accessions:
    • O75268
    • O95781

    Protein attributes for ANKRD24 Gene

    1146 amino acids
    Molecular mass:
    124187 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC33490.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAD15479.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD24 Gene


neXtProt entry for ANKRD24 Gene

Post-translational modifications for ANKRD24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD24 Gene

No data available for DME Specific Peptides for ANKRD24 Gene

Domains & Families for ANKRD24 Gene

Gene Families for ANKRD24 Gene

Protein Domains for ANKRD24 Gene

Suggested Antigen Peptide Sequences for ANKRD24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 ANK repeats.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with ANKRD24: view

Function for ANKRD24 Gene

Phenotypes for ANKRD24 Gene

GenomeRNAi human phenotypes for ANKRD24:
genes like me logo Genes that share phenotypes with ANKRD24: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD24 Gene

Localization for ANKRD24 Gene

Subcellular locations from

Jensen Localization Image for ANKRD24 Gene COMPARTMENTS Subcellular localization image for ANKRD24 gene
Compartment Confidence
nucleus 3
cytoskeleton 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD24 Gene

Pathways & Interactions for ANKRD24 Gene

SuperPathways for ANKRD24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD24 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD24 Gene

Drugs & Compounds for ANKRD24 Gene

No Compound Related Data Available

Transcripts for ANKRD24 Gene

mRNA/cDNA for ANKRD24 Gene

(12) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD24 Gene

Ankyrin repeat domain 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD24 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24
SP1: -
SP3: -

Relevant External Links for ANKRD24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD24 Gene

mRNA expression in normal human tissues for ANKRD24 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD24 Gene

This gene is overexpressed in Brain - Cortex (x7.5), Brain - Frontal Cortex (BA9) (x6.4), and Brain - Anterior cingulate cortex (BA24) (x4.4).

Protein differential expression in normal tissues from HIPED for ANKRD24 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (27.9), Kidney (9.6), and Fetal gut (9.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD24 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD24 Gene:


SOURCE GeneReport for Unigene cluster for ANKRD24 Gene:

genes like me logo Genes that share expression patterns with ANKRD24: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ANKRD24 Gene

Orthologs for ANKRD24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD24 34
  • 83.58 (n)
  • 83.82 (a)
ANKRD24 35
  • 82 (a)
(Canis familiaris)
Mammalia ANKRD24 34
  • 83.76 (n)
  • 83.76 (a)
ANKRD24 35
  • 82 (a)
(Mus musculus)
Mammalia Ankrd24 34
  • 71.09 (n)
  • 67.49 (a)
Ankrd24 16
Ankrd24 35
  • 65 (a)
(Rattus norvegicus)
Mammalia LOC100909645 34
  • 66.52 (n)
  • 61.7 (a)
(Monodelphis domestica)
Mammalia ANKRD24 35
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD24 35
  • 59 (a)
(Pan troglodytes)
Mammalia ANKRD24 35
  • 98 (a)
(Gallus gallus)
Aves ANKRD24 35
  • 42 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 18 (a)
(Danio rerio)
Actinopterygii ankrd24 35
  • 33 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 26 (a)
Species where no ortholog for ANKRD24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD24 Gene

Gene Tree for ANKRD24 (if available)
Gene Tree for ANKRD24 (if available)

Paralogs for ANKRD24 Gene

Paralogs for ANKRD24 Gene

(10) SIMAP similar genes for ANKRD24 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ANKRD24: view

Variants for ANKRD24 Gene

Sequence variations from dbSNP and Humsavar for ANKRD24 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2052191 - 4,200,159(+) TGAGC(A/G)CGGAC reference, missense
rs12978469 - 4,210,359(+) GGAAC(A/G)GAGGC upstream-variant-2KB, reference, missense
rs10413818 - 4,216,913(+) GAGCC(A/G)AGGCC reference, missense
rs353693 - 4,217,210(+) TGGAA(A/C/G/T)CCACA reference, missense
rs10425435 -- 4,223,542(+) agctg(A/G)gacta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD24 Gene

Variant ID Type Subtype PubMed ID
dgv216e215 CNV deletion 23714750
dgv651e214 CNV gain 21293372
esv1448643 CNV deletion 17803354
esv2717991 CNV deletion 23290073
esv2717992 CNV deletion 23290073
esv2717993 CNV deletion 23290073
esv2717994 CNV deletion 23290073
esv32625 CNV gain 17666407
esv3643490 CNV loss 21293372
nsv1121544 CNV deletion 24896259
nsv833716 CNV loss 17160897
nsv833717 CNV loss 17160897
nsv833718 CNV loss 17160897

Variation tolerance for ANKRD24 Gene

Gene Damage Index Score: 9.79; 89.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD24 Gene

Disorders for ANKRD24 Gene

Relevant External Links for ANKRD24

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD24 Gene

Publications for ANKRD24 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 65
  2. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3 65
  3. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3 65
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3 65
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 65

Products for ANKRD24 Gene

Sources for ANKRD24 Gene

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