Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKRD23 Gene

protein-coding   GIFtS: 48
GCID: GC02M097490

Ankyrin Repeat Domain 23

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat Domain 231 2     Muscle Ankyrin Repeat Protein 32 3
DARP2 3 5     MARP32
Diabetes Related Ankyrin Repeat Protein1 2     Ankyrin Repeat Domain-Containing Protein 232
Diabetes-Related Ankyrin Repeat Protein2 3     

External Ids:    HGNC: 244701   Entrez Gene: 2005392   Ensembl: ENSG000001631267   OMIM: 6107365   UniProtKB: Q86SG23   

Export aliases for ANKRD23 gene to outside databases

Previous GC identifers: GC02M096988 GC02M096925 GC02M096867 GC02M091464


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANKRD23 Gene:
This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem
ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator.
Expression of this protein is induced during recovery following starvation. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANKRD23 Gene: 
ANKRD23 (ankyrin repeat domain 23) is a protein-coding gene. Diseases associated with ANKRD23 include dilated cardiomyopathy, and hypoxia. GO annotations related to this gene include titin binding. An important paralog of this gene is ANKRD2.

UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
Function: May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced
signaling pathways and muscle gene expression

Gene Wiki entry for ANKRD23 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022171.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANKRD23 gene promoter:
         SRF   C/EBPbeta   Elk-1   AML1a   p53   Pax-5   SRF (504 AA)   HTF   AP-4   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKRD23 promoter sequence
   Search SABiosciences Chromatin IP Primers for ANKRD23

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

ANKRD23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD23 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M097490:  view genomic region     (about GC identifiers)

Start:
97,490,263 bp from pter      End:
97,523,671 bp from pter
Size:
33,409 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 23  
Size: 305 amino acids; 34297 Da
Subunit: Interacts with titin/TTN and MYPN
Subcellular location: Nucleus. Note=Sarcomeric I-band and some intercalated disks (By similarity)
Secondary accessions: Q711K7 Q8NAJ7
Alternative splicing: 2 isoforms:  Q86SG2-1   Q86SG2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANKRD23: NX_Q86SG2

Explore proteomics data for ANKRD23 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86SG2

  • ANKRD23 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANKRD23 Protein Expression
    REFSEQ proteins: NP_659431.5  
    ENSEMBL proteins: 
     ENSP00000321679   ENSP00000398987   ENSP00000333108  

    Human Recombinant Protein Products for ANKRD23: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ANKRD23
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ANKRD23
    GenScript Custom Purified and Recombinant Proteins Services for ANKRD23
    Novus Biologicals ANKRD23 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0015629actin cytoskeleton IDA--
    GO:0031674I band IEA--

    ANKRD23 for ontologies           About GeneDecksing



    ANKRD23 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ANKRD23
    GenScript Custom Superior Antibodies Services for ANKRD23
    Novus Biologicals ANKRD23 Antibody
    Abcam antibodies for ANKRD23
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibodies for ANKRD23
    LSBio Antibodies in human, mouse, rat for ANKRD23 

    Assay Products for ANKRD23: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ANKRD23
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ANKRD23
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    2 InterPro protein domains:
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q86SG2

    ProtoNet protein and cluster: Q86SG2

    1 Blocks protein domain: IPB002110 Ankyrin repeat signature

    UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
    Similarity: Contains 4 ANK repeats


    ANKRD23 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANR23_HUMAN, Q86SG2
    Function: May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced
    signaling pathways and muscle gene expression

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0031432titin binding IPI14583192
         
    ANKRD23 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ANKRD23:
     Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ankrd23):
     muscle 

    ANKRD23 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ankrd23tm1Krc for ANKRD23

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKRD23 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANKRD23

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANKRD23 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ANKRD23 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANKRD23
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate ANKRD23 (see all 13):
    hsa-miR-3163 hsa-miR-1321 hsa-miR-3673 hsa-miR-206 hsa-miR-452* hsa-miR-1 hsa-miR-520a-5p hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidANKRD23 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANKRD23
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ANKRD23
    Sirion Biotech Customized adenovirus for overexpression of ANKRD23

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ANKRD23 (see all 7)
    OriGene ORF clones in mouse, rat for ANKRD23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD23 (NM_144994)
    Sino Biological Human cDNA Clone for ANKRD23
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23
    Sirion Biotech Customized lentivirus for stable overexpression of ANKRD23 
                         Customized lentivirus expression plasmids for stable overexpression of ANKRD23 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ANKRD23
    Search LifeMap BioReagents cell lines for ANKRD23
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD23

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ANKRD23 (Q86SG23 ENSP000003216794) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYPNQ86TC93, ENSP000003517904I2D: score=2 STRING: ENSP00000351790
    TTNQ8WZ423I2D: score=1 
    --ENSP000003484444STRING: ENSP00000348444
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006631fatty acid metabolic process IEA--

    ANKRD23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANKRD23 (ANR23)

    Search CenterWatch for drugs/clinical trials and news about ANKRD23 / ANR23

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANKRD23 gene: 
    NM_144994.7  

    Unigene Cluster for ANKRD23:

    Ankyrin repeat domain 23
    Hs.643430  [show with all ESTs]
    Unigene Representative Sequence: NM_144994
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476975 ENST00000318357(uc002sxa.3 uc002sxb.3 uc002sxc.3)
    ENST00000418232 ENST00000331001 ENST00000482175 ENST00000462692
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANKRD23
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate ANKRD23 (see all 13):
    hsa-miR-3163 hsa-miR-1321 hsa-miR-3673 hsa-miR-206 hsa-miR-452* hsa-miR-1 hsa-miR-520a-5p hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidANKRD23 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANKRD23
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD23
    Clone
    Products:
         
    OriGene clones in human, mouse for ANKRD23 (see all 7)
    OriGene ORF clones in mouse, rat for ANKRD23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD23 (NM_144994)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23
    Sirion Biotech Customized lentivirus for stable overexpression of ANKRD23 
                         Customized lentivirus expression plasmids for stable overexpression of ANKRD23 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANKRD23
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD23

    Additional mRNA sequence: 

    AF492401.1 AJ315766.1 AK057011.1 AK092564.1 BC107056.2 

    14 DOTS entries:

    DT.210759  DT.95085337  DT.92420589  DT.100682173  DT.100026231  DT.95265061  DT.420076  DT.95262564 
    DT.120995886  DT.120995948  DT.315363  DT.97790152  DT.100674040  DT.100773988 

    24/177 AceView cDNA sequences (see all 177):

    BU176483 AJ315766 AI420401 F35527 AA725010 AI201519 AI784086 AA309912 
    AI160687 AK057011 F26598 BF195943 AK092564 AI672621 AX747600 F36126 
    AJ574563 AA629636 BE550893 BU753444 BF196315 AI492173 AA176735 AI276572 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKRD23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGAAGACAA
    ANKRD23 Expression
    About this image


    See ANKRD23 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANKRD23

    SOURCE GeneReport for Unigene cluster: Hs.643430

    UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
    Tissue specificity: Mainly expressed in heart, skeletal muscle and brown adipose tissues

        SABiosciences Custom PCR Arrays for ANKRD23
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANKRD23
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ANKRD23 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd231 , 5 ankyrin repeat domain 231, 5 86.12(n)1
    82.62(a)1
      1 (15.31 cM)5
    783211  NM_153502.31  NP_705722.21 
     365305345 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD236
    ankyrin repeat domain 23
    51(a)
    1 ↔ 1
    GL343484.1(478458-501838)
    worm
    (Caenorhabditis elegans)
    Secernentea F40G9.176
    Protein F40G9.17
    20(a)
    1 → many
    III(194460-210063)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NAS66
    Proteasome-interacting protein involved in the ass...
    20(a)
    1 → many
    VII(953960-954646)


    ENSEMBL Gene Tree for ANKRD23 (if available)
    TreeFam Gene Tree for ANKRD23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKRD23 gene
    ANKRD22  ANKRD542  PSMD102  ANKRD272  ASB82  ANKRD12  ANKRD442  
    3 SIMAP similar genes for ANKRD23 using alignment to 1 protein entry:     ANR23_HUMAN:
    ANKRD1    PSMD10    ANKRD2

    ANKRD23 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/219 SNPs in ANKRD23 are shown (see all 219)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512027671,2
    --91472111(+) GGTATG/TAACTC 1 -- us2k10--------
    rs1874007561,2
    --97503265(+) CTTGCA/GCCCGA 1 -- ds50010--------
    rs1921869251,2
    --97503443(+) CTGAGG/TTGGAG 1 -- ds50010--------
    rs1155846331,2
    C,F--97503543(+) CACTCG/AGCCTA 1 -- ds50011Minor allele frequency- A:0.06WA 118
    rs1469687191,2
    --97503559(+) CTGTCA/GGCCGG 1 -- ds50010--------
    rs1839797221,2
    --97503602(+) TCCCTG/TGTGAC 1 -- ds50010--------
    rs1114955381,2
    C,F--97503747(+) GTTGTC/TTTCTC 1 -- ut312Minor allele frequency- T:0.02NA 122
    rs1156250041,2
    C,F--97503806(+) GCTGGC/GTGTCG 1 -- ut311Minor allele frequency- G:0.20WA 118
    rs1897868351,2
    --97503840(+) GAAAGA/GTGTGT 1 -- ut310--------
    rs1926940381,2
    --97504111(+) CAGTAC/TAGGCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ANKRD23 (97490263 - 97523671 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ANKRD23:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv650e201CNV Deletion23290073
    dgv4249n71CNV Loss21882294
    nsv874680CNV Loss21882294
    nsv526313CNV Loss19592680
    nsv874677CNV Loss21882294
    esv5003CNV Complex18987735

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKRD23
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKRD23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610736    OMIM disorders: --

    4 diseases for ANKRD23:    About MalaCards
    dilated cardiomyopathy    hypoxia    blindness    insulin resistance


    ANKRD23 for disorders           About GeneDecksing


    Export disorders for ANKRD23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKRD23 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with ANKRD23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals. (PubMed id 12456686)1, 2, 3 Ikeda K.... Yokoyama M. (2003)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. (PubMed id 14583192)1, 2 Miller M.K.... Labeit S. (2003)
    6. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. (PubMed id 15238456)1, 9 Nagueh S.F....Granzier H.L. (2004)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
    10. Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding. (PubMed id 17305703)9 Norton L....Tsintzas K. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 200539 HGNC: 24470 AceView: MGC41816andANKRD23 Ensembl:ENSG00000163126 euGenes: HUgn200539
    ECgene: ANKRD23 H-InvDB: ANKRD23

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKRD23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKRD23 gene:
    Search GeneIP for patents involving ANKRD23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ANKRD23  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ANKRD23  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ANKRD23  
     OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ANKRD23   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ANKRD23   OriGene Custom Protein Services for ANKRD23  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKRD23
     QIAGEN SeqTarget long-range PCR primers for resequencing ANKRD23
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD23
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD23
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD23
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
     GenScript Custom Purified and Recombinant Proteins Services for ANKRD23 GenScript cDNA clones with any tag delivered in your preferred vector for ANKRD23
     GenScript Custom Assay Services for ANKRD23 GenScript Custom Superior Antibodies Services for ANKRD23
     GenScript Custom overexpressing Cell Line Services for ANKRD23 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ANKRD23 promoter
     Search Chromatin IP Primers for ANKRD23
     RT2 qPCR Primer Assay in human, mouse, rat ANKRD23
     Search GNC Networks for ANKRD23
     SABiosciences Custom PCR Arrays for ANKRD23
     Search Tocris compounds for ANKRD23 (ANR23)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ANKRD23
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ANKRD23 antibodies
     ANKRD23 lysates
     Antibodies for ANKRD23
     See all of Abcam's Antibodies, Kits and Proteins for ANKRD23
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for ANKRD23
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23
     SwitchGear 3'UTR luciferase reporter plasmids for ANKRD23
     SwitchGear Promoter luciferase reporter plasmids for ANKRD23
     ThermoFisher Antibodies for ANKRD23
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKRD23
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANKRD23
    Customized:
     lentivirus for stable overexpression of ANKRD23
     lentivirus expression plasmids for stable overexpression of ANKRD23
     adenovirus for overexpression of ANKRD23
     LSBio Antibodies in human, mouse, rat for ANKRD23
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ANKRD23 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4