Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ANKRD23 Gene

protein-coding   GIFtS: 49
GCID: GC02M097490

Ankyrin Repeat Domain 23

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ankyrin Repeat Domain 231 2     Muscle Ankyrin Repeat Protein 32 3
DARP2 3 5     MARP32
Diabetes Related Ankyrin Repeat Protein1 2     Ankyrin Repeat Domain-Containing Protein 232
Diabetes-Related Ankyrin Repeat Protein2 3     

External Ids:    HGNC: 244701   Entrez Gene: 2005392   Ensembl: ENSG000001631267   OMIM: 6107365   UniProtKB: Q86SG23   
ORGUL members:         

Export aliases for ANKRD23 gene to outside databases

Previous GC identifers: GC02M096988 GC02M096925 GC02M096867 GC02M091464


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ANKRD23 Gene:
This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem
ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator.
Expression of this protein is induced during recovery following starvation. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANKRD23 Gene:
ANKRD23 (ankyrin repeat domain 23) is a protein-coding gene. GO annotations related to this gene include titin binding. An important paralog of this gene is ANKRD2.

UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
Function: May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced
signaling pathways and muscle gene expression

Gene Wiki entry for ANKRD23 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANKRD23 gene promoter:
         SRF   C/EBPbeta   Elk-1   AML1a   p53   Pax-5   SRF (504 AA)   HTF   AP-4   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKRD23 promoter sequence
   Search Chromatin IP Primers for ANKRD23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

ANKRD23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD23 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M097490:  view genomic region     (about GC identifiers)

Start:
97,490,263 bp from pter      End:
97,523,671 bp from pter
Size:
33,409 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 23  
Size: 305 amino acids; 34297 Da
Subunit: Interacts with titin/TTN and MYPN
Secondary accessions: Q711K7 Q8NAJ7
Alternative splicing: 2 isoforms:  Q86SG2-1   Q86SG2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANKRD23: NX_Q86SG2

Explore proteomics data for ANKRD23 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ANKRD23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_659431.5  
    ENSEMBL proteins: 
     ENSP00000321679   ENSP00000398987   ENSP00000333108  

    ANKRD23 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ANKRD23
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ANKRD23
    GenScript Custom Purified and Recombinant Proteins Services for ANKRD23
    Novus Biologicals ANKRD23 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for ANKRD23 

     
    Search antibodies-online for proteins for ANKRD23 

     
    Search antibodies-online for peptides for ANKRD23

    ANKRD23 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ANKRD23
    Novus Biologicals ANKRD23 Antibody
    Abcam antibodies for ANKRD23
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for ANKRD23
    antibodies-online antibodies for ANKRD23 (3 products) 

    ANKRD23 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ANKRD23
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ANKRD23
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for ANKRD23 
    antibodies-online kits for ANKRD23 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR028780 ANKRD23
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q86SG2

    ProtoNet protein and cluster: Q86SG2

    1 Blocks protein domain: IPB002110 Ankyrin repeat signature

    UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
    Similarity: Contains 4 ANK repeats


    Find genes that share domains with ANKRD23           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANR23_HUMAN, Q86SG2
    Function: May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced
    signaling pathways and muscle gene expression

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0031432titin binding IPI14583192
         
    Find genes that share ontologies with ANKRD23           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ANKRD23:
     Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ankrd23):
     muscle 

    Find genes that share phenotypes with ANKRD23           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ankrd23tm1Krc for ANKRD23

       genOway: Develop your customized and physiologically relevant rodent model for ANKRD23

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ANKRD23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ANKRD23 (see all 13):
    hsa-miR-3163 hsa-miR-1321 hsa-miR-3673 hsa-miR-206 hsa-miR-452* hsa-miR-1 hsa-miR-520a-5p hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidANKRD23 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ANKRD23
    Predesigned siRNA for gene silencing in human, mouse, rat ANKRD23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ANKRD23

    Clone
    Products:
         
    OriGene clones in human, mouse for ANKRD23 (see all 6)
    OriGene ORF clones in mouse, rat for ANKRD23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD23 (NM_144994)
    Sino Biological Human cDNA Clone for ANKRD23
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ANKRD23
    Browse ESI BIO Cell Lines and PureStem Progenitors for ANKRD23 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ANR23_HUMAN, Q86SG2: Nucleus. Note=Sarcomeric I-band and some intercalated disks (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    cytosol3

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----
    GO:0014704intercalated disc IEA--
    GO:0015629actin cytoskeleton ----
    GO:0030016myofibril ----

    Find genes that share ontologies with ANKRD23           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKRD23
    Interactions:

        Search GeneGlobe Interaction Network for ANKRD23

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for ANKRD23 (Q86SG23 ENSP000003216794) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYPNQ86TC93, ENSP000003517904I2D: score=2 STRING: ENSP00000351790
    TTNQ8WZ423I2D: score=1 
    MORF4L1ENSP000003313104STRING: ENSP00000331310
    --ENSP000003484444STRING: ENSP00000348444
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006631fatty acid metabolic process IEA--
    GO:0009612response to mechanical stimulus IEA--

    Find genes that share ontologies with ANKRD23           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKRD23 (ANR23)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ANKRD23 gene: 
    NM_144994.7  

    Unigene Cluster for ANKRD23:

    Ankyrin repeat domain 23
    Hs.643430  [show with all ESTs]
    Unigene Representative Sequence: NM_144994
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476975 ENST00000318357(uc002sxa.3 uc002sxb.3 uc002sxc.3)
    ENST00000418232 ENST00000331001 ENST00000482175 ENST00000462692
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ANKRD23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ANKRD23 (see all 13):
    hsa-miR-3163 hsa-miR-1321 hsa-miR-3673 hsa-miR-206 hsa-miR-452* hsa-miR-1 hsa-miR-520a-5p hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidANKRD23 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ANKRD23
    Predesigned siRNA for gene silencing in human, mouse, rat ANKRD23
    Clone
    Products:
         
    OriGene clones in human, mouse for ANKRD23 (see all 6)
    OriGene ORF clones in mouse, rat for ANKRD23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD23 (NM_144994)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ANKRD23
      QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
      QuantiFast Probe-based Assays in human, mouse, rat ANKRD23

    Additional mRNA sequence: 

    AF492401.1 AJ315766.1 AK057011.1 AK092564.1 BC107056.2 

    14 DOTS entries:

    DT.210759  DT.95085337  DT.92420589  DT.100682173  DT.100026231  DT.95265061  DT.420076  DT.95262564 
    DT.120995886  DT.120995948  DT.315363  DT.97790152  DT.100674040  DT.100773988 

    Selected AceView cDNA sequences (see all 177):

    AA725010 F26598 AA815160 BE550893 BF516553 AI492173 AA309912 AI420401 
    BF195943 AJ574563 AA629636 AI672621 AK092564 AW139647 CF529198 BF196315 
    AA176735 AK057011 AI160687 F35527 AI866797 AI201519 AI289034 AI927948 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ANKRD23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGAAGACAA
    ANKRD23 Expression
    About this image

    ANKRD23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANKRD23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.643430

    UniProtKB/Swiss-Prot: ANR23_HUMAN, Q86SG2
    Tissue specificity: Mainly expressed in heart, skeletal muscle and brown adipose tissues

        Custom PCR Arrays for ANKRD23
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ANKRD23
    QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
    QuantiFast Probe-based Assays in human, mouse, rat ANKRD23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for ANKRD23 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd231 , 5 ankyrin repeat domain 231, 5 86.12(n)1
    82.62(a)1
      1 (15.31 cM)5
    783211  NM_153502.31  NP_705722.21 
     365305345 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD236
    ankyrin repeat domain 23
    53(a)
    1 ↔ 1
    GL343484.1(478458-501838)
    zebrafish
    (Danio rerio)
    Actinopterygii gabpb16
    GA binding protein transcription factor, beta subu...
    9(a)
    many ↔ many
    18(220618-224045) ENSDARG00000023659


    ENSEMBL Gene Tree for ANKRD23 (if available)
    TreeFam Gene Tree for ANKRD23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ANKRD23 gene
    ANKRD22  GABPB12  GABPB22  ANKRD12  ANKRD62  
    3 SIMAP similar genes for ANKRD23 using alignment to 1 protein entry:     ANR23_HUMAN:
    ANKRD1    PSMD10    ANKRD2

    Find genes that share paralogs with ANKRD23           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ANKRD23 (see all 219)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512027671,2
    --91472111(+) GGTATG/TAACTC 1 -- us2k10--------
    rs1874007561,2
    --97503265(+) CTTGCA/GCCCGA 1 -- ds50010--------
    rs1921869251,2
    --97503443(+) CTGAGG/TTGGAG 1 -- ds50010--------
    rs1155846331,2
    C,F--97503543(+) CACTCG/AGCCTA 1 -- ds50011Minor allele frequency- A:0.06WA 118
    rs1469687191,2
    --97503559(+) CTGTCA/GGCCGG 1 -- ds50010--------
    rs1839797221,2
    --97503602(+) TCCCTG/TGTGAC 1 -- ds50010--------
    rs1114955381,2
    C,F--97503747(+) GTTGTC/TTTCTC 1 -- ut312Minor allele frequency- T:0.02NA 122
    rs1156250041,2
    C,F--97503806(+) GCTGGC/GTGTCG 1 -- ut311Minor allele frequency- G:0.20WA 118
    rs1897868351,2
    --97503840(+) GAAAGA/GTGTGT 1 -- ut310--------
    rs1926940381,2
    --97504111(+) CAGTAC/TAGGCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ANKRD23 (97490263 - 97523671 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ANKRD23:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv650e201CNV Deletion23290073
    dgv4249n71CNV Loss21882294
    nsv874680CNV Loss21882294
    nsv526313CNV Loss19592680
    nsv874677CNV Loss21882294
    esv5003CNV Complex18987735

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKRD23
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKRD23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 610736    OMIM disorders: --


    Find genes that share disorders with ANKRD23           About GenesLikeMe


    Export disorders for ANKRD23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ANKRD23 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ANKRD23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals. (PubMed id 12456686)1, 2, 3 Ikeda K.... Yokoyama M. (J. Biol. Chem. 2003)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. (PubMed id 14583192)1, 2 Miller M.K.... Labeit S. (J. Mol. Biol. 2003)
    6. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. (PubMed id 15238456)1, 9 Nagueh S.F....Granzier H.L. (Circulation 2004)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    10. Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding. (PubMed id 17305703)9 Norton L....Tsintzas K. (Acta Physiol (Oxf) 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 200539 HGNC: 24470 AceView: MGC41816andANKRD23 Ensembl:ENSG00000163126 euGenes: HUgn200539
    ECgene: ANKRD23 H-InvDB: ANKRD23

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ANKRD23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ANKRD23 gene:
    Search GeneIP for patents involving ANKRD23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ANKRD23  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ANKRD23  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ANKRD23  
     OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD23   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ANKRD23   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ANKRD23   OriGene Custom Protein Services for ANKRD23  

     
     
     Block miRNA regulation of human, mouse, rat ANKRD23 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ANKRD23
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD23 Predesigned siRNA for gene silencing in human, mouse, rat ANKRD23
     QuantiFast Probe-based Assays in human, mouse, rat ANKRD23 QuantiTect SYBR Green Assays in human, mouse, rat ANKRD23
     Custom PCR Arrays for ANKRD23 Search Chromatin IP Primers for ANKRD23
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ANKRD23  Search GeneGlobe Interaction Network for ANKRD23
     Regulatory tfbs in ANKRD23 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ANKRD23 GenScript cDNA clones with any tag delivered in your preferred vector for ANKRD23
     GenScript Custom Assay Services for ANKRD23 GenScript Custom overexpressing Cell Line Services for ANKRD23
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ANKRD23 (ANR23)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for ANKRD23
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ANKRD23 antibodies
     ANKRD23 lysates
     Antibodies for ANKRD23
     See all of Abcam's Antibodies, Kits and Proteins for ANKRD23
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for ANKRD23
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD23
     SwitchGear 3'UTR luciferase reporter plasmids for ANKRD23
     SwitchGear Promoter luciferase reporter plasmids for ANKRD23
     ThermoFisher Antibodies for ANKRD23
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD23
     Browse compounds at ApexBio
     Search Addgene for plasmids for ANKRD23
      Search eBioscience for proteins for ANKRD23
      Search eBioscience for elisas for ANKRD23
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for ANKRD23
     antibodies-online antibodies for ANKRD23 (3 products)
     antibodies-online kits for ANKRD23 (4 products)
      Search antibodies-online for peptides for ANKRD23
      Search antibodies-online for proteins for ANKRD23
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ANKRD23 gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4