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Aliases for ANKRD22 Gene

Aliases for ANKRD22 Gene

  • Ankyrin Repeat Domain 22 2 3

External Ids for ANKRD22 Gene

Previous GeneCards Identifiers for ANKRD22 Gene

  • GC10M090247
  • GC10M090572
  • GC10M084214

Summaries for ANKRD22 Gene

GeneCards Summary for ANKRD22 Gene

ANKRD22 (Ankyrin Repeat Domain 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD22 Gene

Genomics for ANKRD22 Gene

Regulatory Elements for ANKRD22 Gene

Genomic Location for ANKRD22 Gene

88,819,899 bp from pter
88,851,975 bp from pter
32,077 bases
Minus strand

Genomic View for ANKRD22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD22 Gene

Proteins for ANKRD22 Gene

  • Protein details for ANKRD22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 22
    Protein Accession:
    Secondary Accessions:
    • B2R9Y7
    • Q8WU06

    Protein attributes for ANKRD22 Gene

    191 amino acids
    Molecular mass:
    21849 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD22 Gene

Proteomics data for ANKRD22 Gene at MOPED

Post-translational modifications for ANKRD22 Gene

No Post-translational modifications

Other Protein References for ANKRD22 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ANKRD22 Gene

Domains for ANKRD22 Gene

Gene Families for ANKRD22 Gene

  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD22 Gene

Suggested Antigen Peptide Sequences for ANKRD22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q5VYY1
  • Contains 4 ANK repeats.
genes like me logo Genes that share domains with ANKRD22: view

Function for ANKRD22 Gene

Gene Ontology (GO) - Molecular Function for ANKRD22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD22: view

Animal Model Products

CRISPR Products

miRNA for ANKRD22 Gene

miRTarBase miRNAs that target ANKRD22

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ANKRD22 Gene

Localization for ANKRD22 Gene

Subcellular locations from

Jensen Localization Image for ANKRD22 Gene COMPARTMENTS Subcellular localization image for ANKRD22 gene
Compartment Confidence
cytosol 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD22 Gene

Pathways for ANKRD22 Gene

SuperPathways for ANKRD22 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD22 Gene


No data available for Pathways by source for ANKRD22 Gene

Transcripts for ANKRD22 Gene

mRNA/cDNA for ANKRD22 Gene

(31) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD22 Gene

Ankyrin repeat domain 22:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD22

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD22 Gene

No ASD Table

Relevant External Links for ANKRD22 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD22 Gene

mRNA expression in normal human tissues for ANKRD22 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD22 Gene

This gene is overexpressed in Whole Blood (8.5), Stomach (8.4), Esophagus - Mucosa (6.5), Skin - Not Sun Exposed (Suprapubic) (5.6), and Skin - Sun Exposed (Lower leg) (5.5).

Protein differential expression in normal tissues for ANKRD22 Gene

This gene is overexpressed in Nasal epithelium (42.6) and Plasma (11.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKRD22 Gene

SOURCE GeneReport for Unigene cluster for ANKRD22 Gene Hs.217484

genes like me logo Genes that share expressions with ANKRD22: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Expression partners for ANKRD22 Gene

Orthologs for ANKRD22 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD22 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD22 35
  • 89.3 (n)
  • 90 (a)
ANKRD22 36
  • 90 (a)
(Canis familiaris)
Mammalia ANKRD22 35
  • 79.82 (n)
  • 84.21 (a)
ANKRD22 36
  • 84 (a)
(Mus musculus)
Mammalia Ankrd22 35
  • 85.09 (n)
  • 86.84 (a)
Ankrd22 16
Ankrd22 36
  • 86 (a)
(Pan troglodytes)
Mammalia ANKRD22 35
  • 99.3 (n)
  • 99.48 (a)
ANKRD22 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ankrd22 35
  • 84.39 (n)
  • 88.42 (a)
(Monodelphis domestica)
Mammalia ANKRD22 36
  • 84 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD22 36
  • 62 (a)
(Gallus gallus)
Aves ANKRD22 35
  • 68.42 (n)
  • 69.47 (a)
ANKRD22 36
  • 69 (a)
(Anolis carolinensis)
Reptilia ANKRD22 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd22 35
  • 64.91 (n)
  • 63.68 (a)
(Danio rerio)
Actinopterygii ankrd22 35
  • 57.94 (n)
  • 51.83 (a)
ankrd22 36
  • 52 (a)
Species with no ortholog for ANKRD22:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD22 Gene

Gene Tree for ANKRD22 (if available)
Gene Tree for ANKRD22 (if available)

Paralogs for ANKRD22 Gene

No data available for Paralogs for ANKRD22 Gene

Variants for ANKRD22 Gene

Sequence variations from dbSNP and Humsavar for ANKRD22 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs962771 -- 88,833,935(-) CGGGG(A/G)AGGTA intron-variant
rs962772 -- 88,833,859(-) TTTCT(A/G)CATCA intron-variant
rs1029024 -- 88,828,778(-) AGATG(C/T)CATGG intron-variant
rs1029025 -- 88,828,404(-) CCAAT(A/G)CTATA intron-variant
rs1147601 -- 88,848,481(+) CTTGC(A/G)TATGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD22 Gene

Variant ID Type Subtype PubMed ID
nsv831941 CNV Gain 17160897
nsv7484 CNV Insertion 18451855
nsv831942 CNV Gain 17160897

Relevant External Links for ANKRD22 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD22 Gene

Disorders for ANKRD22 Gene

Relevant External Links for ANKRD22

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for ANKRD22 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ANKRD22 Gene

Publications for ANKRD22 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48

Products for ANKRD22 Gene

Sources for ANKRD22 Gene

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