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ANKRD20A8P Gene

pseudogene   GIFtS: 24
GCID: GC02M095518

Ankyrin Repeat Domain 20 Family, Member A8, Pseudogene

(Previous name: ankyrin repeat domain 20B)
(Previous symbol: ANKRD20B)
  Search for ANKRD20A8P
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat Domain 20 Family, Member A8, Pseudogene1 2
ANKRD20B1 2 3
Ankyrin Repeat Domain 20B1
Ankyrin Repeat Domain-Containing Protein 20A Pseudogene3

External Ids:    HGNC: 236661   Entrez Gene: 7291712   Ensembl: ENSG000002290897   UniProtKB: Q5CZ793   

Export aliases for ANKRD20A8P gene to outside databases

Previous GC identifers: GC02M089463 GC02M095428 GC02M095429 GC02M095440 GC02M095474 GC02M095492


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ANKRD20A8P Gene:
ANKRD20A8P (ankyrin repeat domain 20 family, member A8, pseudogene) is a pseudogene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ANKRD20A8P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ANKRD20A8P

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD20A8P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.1   Ensembl cytogenetic band:  2q11.1   HGNC cytogenetic band: 2q11.1

ANKRD20A8P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD20A8P gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M095518:  view genomic region     (about GC identifiers)

Start:
95,426,673 bp from pter      End:
95,523,027 bp from pter
Size:
96,355 bases      Orientation:
minus strand

1 alternative location:
Chr2-,NW_003571032 198,504-294,651     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: AN20B_HUMAN, Q5CZ79 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 20B  
Size: 823 amino acids; 93909 Da
Sequence caution: Sequence=CAI56787.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NC18
Alternative splicing: 2 isoforms:  Q5CZ79-1   Q5CZ79-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANKRD20A8P: NX_Q5CZ79

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q5CZ79

    ProtoNet protein and cluster: Q5CZ79

    UniProtKB/Swiss-Prot: AN20B_HUMAN, Q5CZ79
    Similarity: Contains 6 ANK repeats


    Find genes that share domains with ANKRD20A8P           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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      --

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKRD20A8P
    Interactions:

        Search GeneGlobe Interaction Network for ANKRD20A8P

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKRD20A8P (AN20B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    Unigene Cluster for ANKRD20A8P:

    Ankyrin repeat domain 20 family, member A8, pseudogene
    Hs.456852  [show with all ESTs]
    Unigene Representative Sequence: CR936649
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000590226 ENST00000432432 ENST00000446135(uc010fhq.2 uc010fhp.3)

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    Additional mRNA sequence: 

    CR936649.1 NR_003366.2 

    3 DOTS entries:

    DT.120970585  DT.120958692  DT.120958690 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANKRD20A8P expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANKRD20A8P Expression
    About this image

    ANKRD20A8P Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.456852
        Custom PCR Arrays for ANKRD20A8P
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    ENSEMBL Gene Tree for ANKRD20A8P (if available)
    TreeFam Gene Tree for ANKRD20A8P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANKRD20A8P gene
    12 SIMAP similar genes for ANKRD20A8P using alignment to 1 protein entry:     AN20B_HUMAN:
    ANKRD20A1    ANKRD20A2    ANKRD20A3    ANKRD20A4    ANKRD19P    ANKRD30BL
    MGC26718    ANKRD36BP1    PRED4    ANKRD62    ANKRD18B    ANKRD18A

    Find genes that share paralogs with ANKRD20A8P           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANKRD20A8P (see all 2648)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1891616151,2
    C--95429057(+) CAGTCC/TCCACT 1 -- int10--------
    rs1453927191,2
    --95429061(+) CCCCAA/CTGACC 1 -- int10--------
    rs1815368041,2
    --95429132(+) GACCCA/CCATCA 1 -- int10--------
    rs1156427131,2
    C,F--95429197(+) TAAACC/TAGGAC 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1873610071,2
    --95429208(+) TTTACC/TGACAA 1 -- int10--------
    rs1922646061,2
    --95429225(+) ACTGAC/TCTGGA 1 -- int10--------
    rs1176264621,2
    F--95429389(+) CAAAGG/CCCTCA 1 -- int11Minor allele frequency- C:0.03EA 120
    rs118856871,2
    C,F,H--95429424(+) tcttaC/Ttgaca 1 -- int123Minor allele frequency- T:0.12NS EA NA WA 2646
    rs1408323941,2
    C--95429450(+) TGTTCC/TACCGA 1 -- int10--------
    rs1148943501,2
    F--95429609(+) GGCACG/ACACTG 1 -- int11Minor allele frequency- A:0.03NA 120

    HapMap Linkage Disequilibrium report for ANKRD20A8P (95426673 - 95523027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for ANKRD20A8P:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659810CNV Deletion23128226
    esv2662784CNV Deletion23128226
    esv2671209CNV Deletion23128226
    esv1002390CNV Insertion20482838
    nsv511795CNV Loss21212237
    esv24702CNV Gain19812545
    nsv10088CNV Gain+Loss18304495
    essv23304CNV CNV17122850
    dgv1227e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANKRD20A8P gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ANKRD20A8P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 729171 HGNC: 23666 Ensembl:ENSG00000229089 euGenes: HUgn729171 ECgene: ANKRD20A8P
    H-InvDB: ANKRD20A8P

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANKRD20A8P Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANKRD20A8P gene:
    Search GeneIP for patents involving ANKRD20A8P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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