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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKRD20A8P Gene

pseudogene   GIFtS: 26
GCID: GC02M095492

Ankyrin Repeat Domain 20 Family, Member A8, Pseudogene

(Previous name: ankyrin repeat domain 20B)
(Previous symbol: ANKRD20B)
  Search for ANKRD20A8P
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Ankyrin Repeat Domain 20 Family, Member A8, Pseudogene1 2
ANKRD20B1 2 3
Ankyrin Repeat Domain 20B1
Ankyrin Repeat Domain-Containing Protein 20A Pseudogene3

External Ids:    HGNC: 236661   Entrez Gene: 7291712   Ensembl: ENSG000002290897   UniProtKB: Q5CZ793   
ORGUL members:         
NONCODE14:n406099      

Export aliases for ANKRD20A8P gene to outside databases

Previous GC identifers: GC02M089463 GC02M095428 GC02M095429 GC02M095440 GC02M095474


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ANKRD20A8P Gene: 
ANKRD20A8P (ankyrin repeat domain 20 family, member A8, pseudogene) is a pseudogene, and is affiliated with the lncRNA class.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022171.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ANKRD20A8P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ANKRD20A8P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD20A8P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.1   Ensembl cytogenetic band:  2q11.1   HGNC cytogenetic band: 2q11.1

ANKRD20A8P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD20A8P gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M095492:  view genomic region     (about GC identifiers)

Start:
95,426,673 bp from pter      End:
95,523,027 bp from pter
Size:
96,355 bases      Orientation:
minus strand

1 alternative location:
Chr2-,NW_003571032 198,504-294,651     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AN20B_HUMAN, Q5CZ79 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 20B  
Size: 823 amino acids; 93909 Da
Sequence caution: Sequence=CAI56787.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NC18
Alternative splicing: 2 isoforms:  Q5CZ79-1   Q5CZ79-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANKRD20A8P: NX_Q5CZ79

Post-translational modifications:

  • View modification sites using PhosphoSitePlus (ANKRD20B)
  • View neXtProt modification sites for NX_Q5CZ79

  • ANKRD20A8P Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q5CZ79

    ProtoNet protein and cluster: Q5CZ79

    UniProtKB/Swiss-Prot: AN20B_HUMAN, Q5CZ79
    Similarity: Contains 6 ANK repeats


    ANKRD20A8P for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD20A8P

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ANKRD20A8P (AN20B)

    Search CenterWatch for drugs/clinical trials and news about ANKRD20A8P

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    Unigene Cluster for ANKRD20A8P:

    Ankyrin repeat domain 20 family, member A8, pseudogene
    Hs.456852  [show with all ESTs]
    Unigene Representative Sequence: CR936649
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000590226 ENST00000432432 ENST00000446135(uc010fhq.2 uc010fhp.3)

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    Additional mRNA sequence: 

    CR936649.1 NR_003366.2 

    3 DOTS entries:

    DT.120970585  DT.120958692  DT.120958690 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKRD20A8P expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANKRD20A8P Expression
    About this image


    Genevestigator expression for ANKRD20A8P

    SOURCE GeneReport for Unigene cluster: Hs.456852
        SABiosciences Custom PCR Arrays for ANKRD20A8P
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for ANKRD20A8P (if available)
    TreeFam Gene Tree for ANKRD20A8P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKRD20A8P gene
    12 SIMAP similar genes for ANKRD20A8P using alignment to 1 protein entry:     AN20B_HUMAN:
    ANKRD20A1    ANKRD20A2    ANKRD20A3    ANKRD20A4    ANKRD19P    ANKRD30BL
    MGC26718    ANKRD36BP1    PRED4    ANKRD62    ANKRD18B    ANKRD18A

    ANKRD20A8P for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2648 SNPs in ANKRD20A8P are shown (see all 2648)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1891616151,2
    C--95429057(+) CAGTCC/TCCACT 1 -- int10--------
    rs1453927191,2
    --95429061(+) CCCCAA/CTGACC 1 -- int10--------
    rs1815368041,2
    --95429132(+) GACCCA/CCATCA 1 -- int10--------
    rs1156427131,2
    C,F--95429197(+) TAAACC/TAGGAC 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1873610071,2
    --95429208(+) TTTACC/TGACAA 1 -- int10--------
    rs1922646061,2
    --95429225(+) ACTGAC/TCTGGA 1 -- int10--------
    rs1176264621,2
    F--95429389(+) CAAAGG/CCCTCA 1 -- int11Minor allele frequency- C:0.03EA 120
    rs118856871,2
    C,F,H--95429424(+) tcttaC/Ttgaca 1 -- int123Minor allele frequency- T:0.12NS EA NA WA 2646
    rs1408323941,2
    C--95429450(+) TGTTCC/TACCGA 1 -- int10--------
    rs1148943501,2
    F--95429609(+) GGCACG/ACACTG 1 -- int11Minor allele frequency- A:0.03NA 120

    HapMap Linkage Disequilibrium report for ANKRD20A8P (95426673 - 95523027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for ANKRD20A8P:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2659810CNV Deletion23128226
    esv2662784CNV Deletion23128226
    esv2671209CNV Deletion23128226
    esv1002390CNV Insertion20482838
    nsv511795CNV Loss21212237
    esv24702CNV Gain19812545
    nsv10088CNV Gain+Loss18304495
    essv23304CNV CNV17122850
    dgv1227e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKRD20A8P gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ANKRD20A8P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 729171 HGNC: 23666 Ensembl:ENSG00000229089 euGenes: HUgn729171 ECgene: ANKRD20A8P
    H-InvDB: ANKRD20A8P

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKRD20A8P Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKRD20A8P gene:
    Search GeneIP for patents involving ANKRD20A8P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for ANKRD20A8P
     Browse SwitchGear Promoter luciferase reporter plasmids for ANKRD20A8P
     Search ThermoFisher Antibodies for ANKRD20A8P
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD20A8P
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKRD20A8P
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANKRD20A8P
    Customized:
     lentivirus for stable overexpression of ANKRD20A8P
     lentivirus expression plasmids for stable overexpression of ANKRD20A8P
     adenovirus for overexpression of ANKRD20A8P
     Search LSBio for Antibodies for ANKRD20A8P
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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