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Aliases for ANKRD20A2 Gene

Aliases for ANKRD20A2 Gene

  • Ankyrin Repeat Domain 20 Family Member A2 2 3 5
  • Ankyrin Repeat Domain 20 Family, Member A2 2

External Ids for ANKRD20A2 Gene

Previous GeneCards Identifiers for ANKRD20A2 Gene

  • GC09P045519
  • GC09P042358

Summaries for ANKRD20A2 Gene

GeneCards Summary for ANKRD20A2 Gene

ANKRD20A2 (Ankyrin Repeat Domain 20 Family Member A2) is a Protein Coding gene. An important paralog of this gene is ANKRD20A4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD20A2 Gene

Genomics for ANKRD20A2 Gene

Regulatory Elements for ANKRD20A2 Gene


Promoters for ANKRD20A2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001908860 -78 2000

Genomic Location for ANKRD20A2 Gene

Chromosome:
9
Start:
40,223,078 bp from pter
End:
40,282,461 bp from pter
Size:
59,384 bases
Orientation:
Plus strand

Genomic View for ANKRD20A2 Gene

Genes around ANKRD20A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD20A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD20A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD20A2 Gene

Proteins for ANKRD20A2 Gene

  • Protein details for ANKRD20A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SQ80-A20A2_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 20A2
    Protein Accession:
    Q5SQ80

    Protein attributes for ANKRD20A2 Gene

    Size:
    823 amino acids
    Molecular mass:
    94087 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD20A2 Gene

Post-translational modifications for ANKRD20A2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD20A2 Gene

No data available for DME Specific Peptides for ANKRD20A2 Gene

Domains & Families for ANKRD20A2 Gene

Gene Families for ANKRD20A2 Gene

Protein Domains for ANKRD20A2 Gene

Suggested Antigen Peptide Sequences for ANKRD20A2 Gene

Graphical View of Domain Structure for InterPro Entry

Q5SQ80

UniProtKB/Swiss-Prot:

A20A2_HUMAN :
  • Contains 5 ANK repeats.
Similarity:
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with ANKRD20A2: view

Function for ANKRD20A2 Gene

Phenotypes for ANKRD20A2 Gene

GenomeRNAi human phenotypes for ANKRD20A2:
genes like me logo Genes that share phenotypes with ANKRD20A2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD20A2 Gene

Localization for ANKRD20A2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD20A2 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD20A2 Gene

Pathways & Interactions for ANKRD20A2 Gene

SuperPathways for ANKRD20A2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD20A2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD20A2 Gene

Transcripts for ANKRD20A2 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD20A2 Gene

No ASD Table

Relevant External Links for ANKRD20A2 Gene

GeneLoc Exon Structure for
ANKRD20A2
ECgene alternative splicing isoforms for
ANKRD20A2

Expression for ANKRD20A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ANKRD20A2 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD20A2 Gene

This gene is overexpressed in Testis (x8.2).

NURSA nuclear receptor signaling pathways regulating expression of ANKRD20A2 Gene:

ANKRD20A2
genes like me logo Genes that share expression patterns with ANKRD20A2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ANKRD20A2 Gene

Orthologs for ANKRD20A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD20A2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC738297 34
  • 98.62 (n)
-- 35
  • 97 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 43 (a)
ManyToMany
-- 35
  • 42 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 16 (a)
ManyToMany
-- 35
  • 16 (a)
ManyToMany
-- 35
  • 15 (a)
ManyToMany
-- 35
  • 14 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm1758 35
  • 36 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 34 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 11 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 18 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 41 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 35
  • 9 (a)
OneToMany
Species where no ortholog for ANKRD20A2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD20A2 Gene

ENSEMBL:
Gene Tree for ANKRD20A2 (if available)
TreeFam:
Gene Tree for ANKRD20A2 (if available)

Paralogs for ANKRD20A2 Gene

genes like me logo Genes that share paralogs with ANKRD20A2: view

Variants for ANKRD20A2 Gene

Sequence variations from dbSNP and Humsavar for ANKRD20A2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10118450 -- 40,242,797(+) GTTTT(A/C)ATAAT intron-variant
rs10436207 -- 40,225,702(-) ACTGA(C/T)AAACT intron-variant
rs10436208 -- 40,225,512(-) AGATG(A/G)CAGAA intron-variant
rs10436209 -- 40,225,511(-) GATGA(C/T)AGAAT intron-variant
rs10436210 -- 40,225,422(-) GTTCA(A/T)TATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD20A2 Gene

Variant ID Type Subtype PubMed ID
dgv4326e59 CNV duplication 20981092
dgv4327e59 CNV duplication 20981092
dgv85n82 CNV duplication 23825009
esv3401603 CNV duplication 20981092
esv3419087 CNV duplication 20981092
esv3439554 CNV duplication 20981092
nsv1020579 CNV gain+loss 25217958
nsv1033842 CNV gain 25217958
nsv1075212 CNV deletion 25765185
nsv1077111 CNV deletion 25765185
nsv1115803 CNV duplication 24896259
nsv1122216 CNV deletion 24896259
nsv1128996 CNV duplication 24896259
nsv1132688 CNV duplication 24896259
nsv1132689 CNV duplication 24896259
nsv1145222 CNV deletion 24896259
nsv1146494 CNV duplication 26484159
nsv8485 CNV loss 18304495
nsv951732 CNV deletion 24416366
nsv969544 CNV duplication 23825009
nsv969545 CNV duplication 23825009
nsv969546 CNV duplication 23825009
nsv969548 CNV duplication 23825009
nsv969549 CNV duplication 23825009
nsv969550 CNV duplication 23825009
nsv972702 CNV duplication 23825009
nsv973242 CNV duplication 23825009
nsv973244 CNV duplication 23825009
nsv973245 CNV duplication 23825009
nsv973591 CNV duplication 23825009
nsv973592 CNV duplication 23825009
nsv982396 CNV duplication 23825009
nsv982397 CNV duplication 23825009
nsv982398 CNV duplication 23825009
nsv982400 CNV duplication 23825009
nsv982401 CNV duplication 23825009
nsv982402 CNV duplication 23825009

Variation tolerance for ANKRD20A2 Gene

Gene Damage Index Score: 3.27; 52.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD20A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD20A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD20A2 Gene

Disorders for ANKRD20A2 Gene

Relevant External Links for ANKRD20A2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD20A2

No disorders were found for ANKRD20A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD20A2 Gene

Publications for ANKRD20A2 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ANKRD20A2 Gene

Sources for ANKRD20A2 Gene

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