Aliases for ANKRD20A2 Gene
Aliases for ANKRD20A2 Gene
External Ids for ANKRD20A2 Gene
- HGNC: 31979
- Entrez Gene: 441430
- Ensembl: ENSG00000183148
- UniProtKB: Q5SQ80
Previous GeneCards Identifiers for ANKRD20A2 Gene
- GC09P045519
- GC09P042358
Summaries for ANKRD20A2 Gene
GeneCards Summary for ANKRD20A2 Gene
ANKRD20A2 (Ankyrin Repeat Domain 20 Family Member A2) is a Protein Coding gene. An important paralog of this gene is ANKRD20A1.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD20A2 Gene
Genomics for ANKRD20A2 Gene
Regulatory Elements for ANKRD20A2 Gene
Promoters for ANKRD20A2 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|---|---|---|
| ENSR00000235075 | 122 | 801 | CTCF SMC3 REST RAD21 |
Regulatory Element Products
Genomic Location for ANKRD20A2 Gene
- Chromosome:
- 9
- Start:
- 40,223,078 bp from pter
- End:
- 40,282,461 bp from pter
- Size:
- 59,384 bases
- Orientation:
- Plus strand
Genomic View for ANKRD20A2 Gene
Genes around ANKRD20A2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9p11.2 by Ensembl
- 9p11.2 by Entrez Gene
- 9p11.2 by HGNC
ANKRD20A2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANKRD20A2 Gene
Proteins for ANKRD20A2 Gene
-
Protein details for ANKRD20A2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5SQ80-A20A2_HUMAN
- Recommended name:
- Ankyrin repeat domain-containing protein 20A2
- Protein Accession:
- Q5SQ80
Protein attributes for ANKRD20A2 Gene
- Size:
- 823 amino acids
- Molecular mass:
- 94087 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ANKRD20A2 Gene
Other Protein References for ANKRD20A2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for ANKRD20A2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ANKRD20A2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ANKRD20A2
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- Search GeneTex for Proteins for ANKRD20A2
Assay Products
No data available for DME Specific Peptides for ANKRD20A2 Gene
Domains & Families for ANKRD20A2 Gene
Gene Families for ANKRD20A2 Gene
Protein Domains for ANKRD20A2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ANKRD20A2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ANKRD20A2 Gene
Function for ANKRD20A2 Gene
Phenotypes for ANKRD20A2 Gene
- GenomeRNAi human phenotypes for ANKRD20A2:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKRD20A2 gene
-
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CRISPR Products
-
OriGene CRISPR knockouts for ANKRD20A2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKRD20A2
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miRNA Products
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Inhibitory RNA Products
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Clone Products
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- VectorBuilder custom plasmid, inducible vectors for ANKRD20A2
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ANKRD20A2
-
ViGene Biosciences adenoviral particle packaged cDNA for ANKRD20A2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKRD20A2 gene
-
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Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD20A2 Gene
Localization for ANKRD20A2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD20A2 Gene
Pathways & Interactions for ANKRD20A2 Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for ANKRD20A2 Gene
Transcripts for ANKRD20A2 Gene
mRNA/cDNA for ANKRD20A2 Gene
- (5) REFSEQ mRNAs :
- (69) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for ANKRD20A2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKRD20A2
- GenScript: Design CRISPR guide RNA sequences for ANKRD20A2
miRNA Products
- Search ViGene Biosciences for ANKRD20A2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ANKRD20A2
- Browse OriGene Inhibitory RNA Products For ANKRD20A2
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKRD20A2 gene
Clone Products
-
OriGene ORF clones in human for ANKRD20A2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ANKRD20A2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKRD20A2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for ANKRD20A2 Gene
mRNA differential expression in normal tissues according to GTEx for ANKRD20A2 Gene
This gene is overexpressed in Testis (x8.2).
NURSA nuclear receptor signaling pathways regulating expression of ANKRD20A2 Gene:
ANKRD20A2Primer Products
-
OriGene qPCR primer pairs for ANKRD20A2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD20A2 Gene
Orthologs for ANKRD20A2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC738297 34 |
|
||
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Gm1758 35 |
|
ManyToMany | |
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | -- 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | ANKRD7 35 |
|
OneToMany |
- Species where no ortholog for ANKRD20A2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ANKRD20A2 Gene
Paralogs for ANKRD20A2 Gene
- ANKRD20A1 5
- ANKRD20A4 5
- ANKRD20A3 5
- ANKRD26 5
- ANKRD18B 5
- ANKRD18A 5
- ANKRD62 5
- ANKRD30B 5
- ANKRD30A 5
- ANKRD36 5
- ANKRD36C 5
- ANKRD36B 5
- CCDC144A 5
- POTEA 5
- ENSG00000266302 5
- POTEF 5
- POTEE 5
- POTEJ 5
- POTEI 5
- LOC100288966 5
- POTEB3 5
- LOC102723502 5
- POTEB 5
- POTED 5
- POTEB2 5
- POTEC 5
- POTEG 5
- POTEM 5
- POTEH 5
- ANKRD7 5
- ANKRD30BL 5
- ANKRD20A3 34
- ANKRD20A1 34
- ANKRD20A4 34
(18) SIMAP similar genes for ANKRD20A2 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for ANKRD20A2 Gene
Variants for ANKRD20A2 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000360242 | -- | 40,244,845(+) | TAATA(C/T)TTTGA | intron-variant | |
| rs1000529352 | -- | 40,254,399(+) | AATTT(C/T)GCAAT | intron-variant | |
| rs1000581926 | -- | 40,247,920(+) | CATGC(C/G)TGACT | intron-variant | |
| rs1001917273 | -- | 40,232,540(+) | TAAGT(A/G)TTTAT | intron-variant | |
| rs1002264850 | -- | 40,241,374(+) | ACCAA(C/T)ATGTA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4326e59 | CNV | duplication | 20981092 |
| dgv4327e59 | CNV | duplication | 20981092 |
| dgv85n82 | CNV | duplication | 23825009 |
| esv3401603 | CNV | duplication | 20981092 |
| esv3419087 | CNV | duplication | 20981092 |
| esv3439554 | CNV | duplication | 20981092 |
| nsv1020579 | CNV | gain+loss | 25217958 |
| nsv1033842 | CNV | gain | 25217958 |
| nsv1075212 | CNV | deletion | 25765185 |
| nsv1077111 | CNV | deletion | 25765185 |
| nsv1115803 | CNV | duplication | 24896259 |
| nsv1122216 | CNV | deletion | 24896259 |
| nsv1128996 | CNV | duplication | 24896259 |
| nsv1132688 | CNV | duplication | 24896259 |
| nsv1132689 | CNV | duplication | 24896259 |
| nsv1145222 | CNV | deletion | 24896259 |
| nsv1146494 | CNV | duplication | 26484159 |
| nsv8485 | CNV | loss | 18304495 |
| nsv951732 | CNV | deletion | 24416366 |
| nsv969544 | CNV | duplication | 23825009 |
| nsv969545 | CNV | duplication | 23825009 |
| nsv969546 | CNV | duplication | 23825009 |
| nsv969548 | CNV | duplication | 23825009 |
| nsv969549 | CNV | duplication | 23825009 |
| nsv969550 | CNV | duplication | 23825009 |
| nsv972702 | CNV | duplication | 23825009 |
| nsv973242 | CNV | duplication | 23825009 |
| nsv973244 | CNV | duplication | 23825009 |
| nsv973245 | CNV | duplication | 23825009 |
| nsv973591 | CNV | duplication | 23825009 |
| nsv973592 | CNV | duplication | 23825009 |
| nsv982396 | CNV | duplication | 23825009 |
| nsv982397 | CNV | duplication | 23825009 |
| nsv982398 | CNV | duplication | 23825009 |
| nsv982400 | CNV | duplication | 23825009 |
| nsv982401 | CNV | duplication | 23825009 |
| nsv982402 | CNV | duplication | 23825009 |
Gene Damage Index Score:
3.27;
52.95% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ANKRD20A2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ANKRD20A2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD20A2 Gene
Disorders for ANKRD20A2 Gene
Relevant External Links for ANKRD20A2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ANKRD20A2
No disorders were found for ANKRD20A2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD20A2 Gene
Publications for ANKRD20A2 Gene
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for ANKRD20A2 Gene
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- VectorBuilder custom plasmid, inducible vectors for ANKRD20A2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKRD20A2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ANKRD20A2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
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- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
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- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
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- (141) ENCODE
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- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer