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Aliases for ANKRD20A1 Gene

Aliases for ANKRD20A1 Gene

  • Ankyrin Repeat Domain 20 Family Member A1 2 3 5
  • Ankyrin Repeat Domain 20A 2 3
  • ANKRD20A 3 4
  • Ankyrin Repeat Domain-Containing Protein 20A1 3
  • Ankyrin Repeat Domain 20 Family, Member A1 2

External Ids for ANKRD20A1 Gene

Previous HGNC Symbols for ANKRD20A1 Gene

  • ANKRD20A

Previous GeneCards Identifiers for ANKRD20A1 Gene

  • GC09P066417
  • GC09P067517
  • GC09P067926
  • GC02M089509

Summaries for ANKRD20A1 Gene

GeneCards Summary for ANKRD20A1 Gene

ANKRD20A1 (Ankyrin Repeat Domain 20 Family Member A1) is a Protein Coding gene. Diseases associated with ANKRD20A1 include Behcet Syndrome. An important paralog of this gene is ANKRD20A2.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD20A1 Gene

Genomics for ANKRD20A1 Gene

Regulatory Elements for ANKRD20A1 Gene


Promoters for ANKRD20A1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000235459 253 1200 CTCF

Genomic Location for ANKRD20A1 Gene

Chromosome:
9
Start:
67,859,147 bp from pter
End:
67,902,394 bp from pter
Size:
43,248 bases
Orientation:
Plus strand

Genomic View for ANKRD20A1 Gene

Genes around ANKRD20A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD20A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD20A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD20A1 Gene

Proteins for ANKRD20A1 Gene

  • Protein details for ANKRD20A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TYW2-A20A1_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 20A1
    Protein Accession:
    Q5TYW2
    Secondary Accessions:
    • Q9H0H6

    Protein attributes for ANKRD20A1 Gene

    Size:
    823 amino acids
    Molecular mass:
    94048 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD20A1 Gene

Post-translational modifications for ANKRD20A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD20A1 Gene

No data available for DME Specific Peptides for ANKRD20A1 Gene

Domains & Families for ANKRD20A1 Gene

Gene Families for ANKRD20A1 Gene

Protein Domains for ANKRD20A1 Gene

Suggested Antigen Peptide Sequences for ANKRD20A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKRD20A1: view

No data available for UniProtKB/Swiss-Prot for ANKRD20A1 Gene

Function for ANKRD20A1 Gene

genes like me logo Genes that share phenotypes with ANKRD20A1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD20A1 Gene

Localization for ANKRD20A1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD20A1 gene
Compartment Confidence
plasma membrane 4

Gene Ontology (GO) - Cellular Components for ANKRD20A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with ANKRD20A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANKRD20A1 Gene

Pathways & Interactions for ANKRD20A1 Gene

SuperPathways for ANKRD20A1 Gene

No Data Available

Interacting Proteins for ANKRD20A1 Gene

Gene Ontology (GO) - Biological Process for ANKRD20A1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD20A1 Gene

Transcripts for ANKRD20A1 Gene

Unigene Clusters for ANKRD20A1 Gene

Ankyrin repeat domain 20 family, member A1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD20A1 Gene

No ASD Table

Relevant External Links for ANKRD20A1 Gene

GeneLoc Exon Structure for
ANKRD20A1
ECgene alternative splicing isoforms for
ANKRD20A1

Expression for ANKRD20A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD20A1 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD20A1 Gene

This gene is overexpressed in Testis (x7.2).

Protein differential expression in normal tissues from HIPED for ANKRD20A1 Gene

This gene is overexpressed in Pancreatic juice (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKRD20A1 Gene



Protein tissue co-expression partners for ANKRD20A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD20A1 Gene:

ANKRD20A1

SOURCE GeneReport for Unigene cluster for ANKRD20A1 Gene:

Hs.632671
genes like me logo Genes that share expression patterns with ANKRD20A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD20A1 Gene

Orthologs for ANKRD20A1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ANKRD20A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC738297 34
  • 98.58 (n)
Species where no ortholog for ANKRD20A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD20A1 Gene

ENSEMBL:
Gene Tree for ANKRD20A1 (if available)
TreeFam:
Gene Tree for ANKRD20A1 (if available)

Paralogs for ANKRD20A1 Gene

genes like me logo Genes that share paralogs with ANKRD20A1: view

Variants for ANKRD20A1 Gene

Sequence variations from dbSNP and Humsavar for ANKRD20A1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000594903 -- 67,892,711(+) ACCTC(A/C)AACTC intron-variant
rs1000960790 -- 67,891,148(+) AATTA(C/G)CTGGG intron-variant
rs1001447391 -- 67,886,176(+) TGGGG(A/T)CTTGG intron-variant
rs1001883648 -- 67,882,641(+) TTACT(C/T)TTTAT intron-variant
rs1002481347 -- 67,895,978(+) AGAAT(C/G)TTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD20A1 Gene

Variant ID Type Subtype PubMed ID
nsv1076174 CNV deletion 25765185
nsv1076670 CNV duplication 25765185
nsv1119302 CNV duplication 24896259
nsv1151719 CNV duplication 26484159
nsv614536 CNV loss 21841781
nsv951479 CNV duplication 24416366
nsv969656 CNV duplication 23825009
nsv969657 CNV duplication 23825009
nsv969658 CNV duplication 23825009
nsv969659 CNV duplication 23825009
nsv973330 CNV duplication 23825009
nsv973331 CNV duplication 23825009
nsv973332 CNV duplication 23825009
nsv973695 CNV duplication 23825009
nsv973699 CNV duplication 23825009
nsv982493 CNV duplication 23825009

Variation tolerance for ANKRD20A1 Gene

Gene Damage Index Score: 6.12; 75.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD20A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD20A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD20A1 Gene

Disorders for ANKRD20A1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ANKRD20A1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
behcet syndrome
  • behcet's disease
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ANKRD20A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD20A1
genes like me logo Genes that share disorders with ANKRD20A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ANKRD20A1 Gene

Publications for ANKRD20A1 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 64
  3. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 64
  4. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with BehAset's disease. (PMID: 19796537) Vural B. … Ozbek U. (Clin. Exp. Rheumatol. 2009) 3 64
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3 64

Products for ANKRD20A1 Gene

Sources for ANKRD20A1 Gene

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