Aliases for ANKRD2 Gene
External Ids for ANKRD2 Gene
Previous GeneCards Identifiers for ANKRD2 Gene
This gene encodes a protein that belongs to the muscle ankyrin repeat protein (MARP) family. A similar gene in rodents is a component of a muscle stress response pathway and plays a role in the stretch-response associated with slow muscle function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
GeneCards Summary for ANKRD2 Gene
ANKRD2 (Ankyrin Repeat Domain 2 (Stretch Responsive Muscle)) is a Protein Coding gene. Diseases associated with ANKRD2 include dubin-johnson syndrome. GO annotations related to this gene include structural constituent of muscle and titin binding. An important paralog of this gene is ANKRD1.
UniProtKB/Swiss-Prot for ANKRD2 Gene
Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress.