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Aliases for ANKRD18B Gene

Aliases for ANKRD18B Gene

  • Ankyrin Repeat Domain 18B 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 18B 3
  • BA255A11.3 3
  • BA255A11.5 3

External Ids for ANKRD18B Gene

Previous GeneCards Identifiers for ANKRD18B Gene

  • GC09P033516
  • GC09U900806

Summaries for ANKRD18B Gene

GeneCards Summary for ANKRD18B Gene

ANKRD18B (Ankyrin Repeat Domain 18B) is a Protein Coding gene. GO annotations related to this gene include nucleotide binding. An important paralog of this gene is ANKRD18A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD18B Gene

Genomics for ANKRD18B Gene

Regulatory Elements for ANKRD18B Gene

Enhancers for ANKRD18B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F033523 1 ENCODE 12.7 -0.3 -259 1.7 SIN3A ZNF2 ZNF48 GLIS2 KLF7 ZNF263 SP3 REST GLIS1 SP7 ANKRD18B AQP3 CYP4F26P ENSG00000228072
GH09F033510 1 ENCODE 12.5 -13.3 -13301 1.9 PKNOX1 ATF1 CREB3L1 SIN3A DMAP1 FEZF1 ZNF2 ZNF48 YY1 ZNF121 ANKRD18B PRSS3 PIR50034 SUGT1P1
GH09F033472 1.1 ENCODE 10.5 -50.8 -50801 2.9 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF302 ASS1P12 SMU1 TOPORS TCEA1P4 ENSG00000228352 DFFBP1 B4GALT1 DDX58 GVQW1 ANKRD18B
GH09F033452 1.2 Ensembl ENCODE 8.9 -70.7 -70665 2.6 ELF3 HDGF MLX ZFP64 ARID4B RAD21 ZNF48 RARA ZNF335 GLIS2 AQP3 NOL6 ANKRD18B CYP4F26P PTENP1 GC09P033453 MIR6851
GH09F033505 1.1 Ensembl ENCODE 9.4 -17.2 -17244 2.3 SIN3A FOS CEBPB USF2 ZEB2 SMARCA4 IKZF1 IRF1 KDM1A MYC NOL6 AQP3 ANKRD18B PIR50034
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKRD18B on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD18B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001302413 -53 1801 SIN3A ZNF2 ZNF48 GLIS2 KLF7 ZNF263 SP3 REST GLIS1 SP7

Genomic Location for ANKRD18B Gene

33,524,353 bp from pter
33,575,969 bp from pter
51,617 bases
Plus strand

Genomic View for ANKRD18B Gene

Genes around ANKRD18B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD18B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD18B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD18B Gene

Proteins for ANKRD18B Gene

  • Protein details for ANKRD18B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 18B
    Protein Accession:

    Protein attributes for ANKRD18B Gene

    1011 amino acids
    Molecular mass:
    118231 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD18B Gene

Post-translational modifications for ANKRD18B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD18B Gene

No data available for DME Specific Peptides for ANKRD18B Gene

Domains & Families for ANKRD18B Gene

Gene Families for ANKRD18B Gene

Protein Domains for ANKRD18B Gene

Suggested Antigen Peptide Sequences for ANKRD18B Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 ANK repeats.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with ANKRD18B: view

Function for ANKRD18B Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD18B Gene

Localization for ANKRD18B Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD18B gene
Compartment Confidence
nucleus 3
mitochondrion 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD18B Gene

Pathways & Interactions for ANKRD18B Gene

SuperPathways for ANKRD18B Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD18B Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD18B Gene

Transcripts for ANKRD18B Gene

mRNA/cDNA for ANKRD18B Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD18B Gene

Ankyrin repeat domain 18B:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD18B Gene

No ASD Table

Relevant External Links for ANKRD18B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD18B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ANKRD18B Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD18B Gene

This gene is overexpressed in Brain - Cerebellum (x11.2), Brain - Cerebellar Hemisphere (x9.5), and Testis (x5.4).

Protein differential expression in normal tissues from HIPED for ANKRD18B Gene

This gene is overexpressed in Tlymphocyte (37.8) and Plasma (29.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD18B Gene

Protein tissue co-expression partners for ANKRD18B Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD18B Gene:


SOURCE GeneReport for Unigene cluster for ANKRD18B Gene:

genes like me logo Genes that share expression patterns with ANKRD18B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKRD18B Gene

Orthologs for ANKRD18B Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD18B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC746826 34
  • 98.94 (n)
  • 98 (a)
(Canis familiaris)
Mammalia -- 35
  • 45 (a)
-- 35
  • 44 (a)
-- 35
  • 42 (a)
-- 35
  • 33 (a)
-- 35
  • 21 (a)
-- 35
  • 21 (a)
-- 35
  • 20 (a)
-- 35
  • 13 (a)
(Mus musculus)
Mammalia Gm1758 35
  • 37 (a)
(Bos Taurus)
Mammalia -- 35
  • 27 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 14 (a)
(Gallus gallus)
Aves -- 35
  • 18 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 42 (a)
(Danio rerio)
Actinopterygii ANKRD7 35
  • 12 (a)
Species where no ortholog for ANKRD18B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD18B Gene

Gene Tree for ANKRD18B (if available)
Gene Tree for ANKRD18B (if available)

Paralogs for ANKRD18B Gene

genes like me logo Genes that share paralogs with ANKRD18B: view

Variants for ANKRD18B Gene

Sequence variations from dbSNP and Humsavar for ANKRD18B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10120325 -- 33,527,795(+) AGGCC(G/T)CATGG intron-variant
rs10123229 -- 33,541,555(+) TAACT(C/T)GGTGT intron-variant
rs10123282 -- 33,575,032(+) CTGCT(C/G)TCTTC intron-variant
rs10813995 -- 33,525,043(+) CCACC(A/T)AGGTA intron-variant
rs10813996 -- 33,531,543(+) TGGTC(C/T)GCTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD18B Gene

Variant ID Type Subtype PubMed ID
nsv982208 CNV duplication 23825009
nsv973207 CNV duplication 23825009
nsv973205 CNV duplication 23825009
nsv1125318 OTHER inversion 24896259
nsv1024207 CNV gain 25217958
esv3576648 CNV gain 25503493

Variation tolerance for ANKRD18B Gene

Gene Damage Index Score: 5.81; 73.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD18B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD18B Gene

Disorders for ANKRD18B Gene

Relevant External Links for ANKRD18B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD18B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD18B Gene

Publications for ANKRD18B Gene

  1. Epigenetic regulation of ANKRD18B in lung cancer. (PMID: 24249358) Liu W.B. … Liu J.Y. (Mol. Carcinog. 2015) 3 64
  2. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4 64
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ANKRD18B Gene

Sources for ANKRD18B Gene

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