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ANKRD17 Gene

protein-coding   GIFtS: 56
GCID: GC04M073940

Ankyrin Repeat Domain 17

  See ANKRD17-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat Domain 171 2     NY-BR-162
Gene Trap Ankyrin Repeat Protein2 3     Ankyrin Repeat Domain-Containing Protein 172
Serologically Defined Breast Cancer Antigen NY-BR-162 3     KIAA06973
GTAR2 3     

External Ids:    HGNC: 235751   Entrez Gene: 260572   Ensembl: ENSG000001324667   UniProtKB: O751793   

Export aliases for ANKRD17 gene to outside databases

Previous GC identifers: GC04M074407 GC04M074406 GC04M074305 GC04M074159 GC04M069746


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANKRD17 Gene:
This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies
in mice suggest that this protein is involved in liver development. Three transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Nov 2013)

GeneCards Summary for ANKRD17 Gene:
ANKRD17 (ankyrin repeat domain 17) is a protein-coding gene. Diseases associated with ANKRD17 include hand, foot and mouth disease, and breast cancer. GO annotations related to this gene include RNA binding. An important paralog of this gene is TANC2.

UniProtKB/Swiss-Prot: ANR17_HUMAN, O75179
Function: Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for
characterization of inductive events involved in hepatic specification (By similarity). Target of enterovirus 71
which is the major etiological agent of HFMD (hand, foot and mouth disease)

Gene Wiki entry for ANKRD17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANKRD17 gene promoter:
         COUP-TF1   AML1a   MAZR   COUP   HNF-4alpha2   HNF-4alpha1   FOXL1   CREB   COUP-TF   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ANKRD17 promoter sequence
   Search Chromatin IP Primers for ANKRD17

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21.1-q21.21

ANKRD17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD17 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M073940:  view genomic region     (about GC identifiers)

Start:
73,939,093 bp from pter      End:
74,124,515 bp from pter
Size:
185,423 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ANR17_HUMAN, O75179 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 17  
Size: 2603 amino acids; 274258 Da
Subunit: Interacts with VP1 capsid protein of enterovirus 71 (EV71)
Sequence caution: Sequence=AAG48253.1; Type=Frameshift; Positions=Several; Sequence=AAH04173.1; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAB15260.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAB15260.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: G5E964 Q6PJ85 Q6PK85 Q6PKA2 Q86XI3 Q8NDR5 Q96I86 Q9H288 Q9H6J9
Alternative splicing: 6 isoforms:  O75179-1   O75179-2   O75179-3   O75179-4   O75179-5   O75179-6   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for ANKRD17: NX_O75179

Explore proteomics data for ANKRD17 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys193, Lys1330
  • Modification sites at PhosphoSitePlus

  • See ANKRD17 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273700.1  NP_115593.3  NP_942592.1  

    ENSEMBL proteins: 
     ENSP00000351416   ENSP00000453434   ENSP00000427151   ENSP00000332265   ENSP00000453294  
     ENSP00000453719  

    ANKRD17 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    4 InterPro protein domains:
     IPR004087 KH_dom
     IPR002110 Ankyrin_rpt
     IPR004088 KH_dom_type_1
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry O75179

    ProtoNet protein and cluster: O75179

    2 Blocks protein domains:
    IPB004087 KH domain
    IPB004088 KH


    UniProtKB/Swiss-Prot: ANR17_HUMAN, O75179
    Similarity: Contains 25 ANK repeats
    Similarity: Contains 1 KH domain


    Find genes that share domains with ANKRD17           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANR17_HUMAN, O75179
    Function: Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for
    characterization of inductive events involved in hepatic specification (By similarity). Target of enterovirus 71
    which is the major etiological agent of HFMD (hand, foot and mouth disease)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with ANKRD17           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ANKRD17:
     High actin ratio cells 

         9 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Ankrd17):
     cardiovascular system  embryogenesis  growth/size/body  homeostasis/metabolism  mortality/aging 
     muscle  nervous system  no phenotypic analysis  normal 

    Find genes that share phenotypes with ANKRD17           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ankrd17tm1.1Yty for ANKRD17

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ANKRD17
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    Block miRNA regulation of human, mouse, rat ANKRD17 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ANKRD17 (see all 85):
    hsa-miR-411* hsa-miR-548j hsa-miR-199a-3p hsa-miR-30d hsa-miR-342-3p hsa-miR-30a hsa-miR-3122 hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidANKRD17 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ANKRD17

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ANR17_HUMAN, O75179: Cytoplasm. Nucleus. Note=Detected around the nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    plasma membrane3
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with ANKRD17           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKRD17
    Interactions:

        Search GeneGlobe Interaction Network for ANKRD17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for ANKRD17 (O751792, 3 ENSP000003514164) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APCP250543, ENSP000002574304I2D: score=3 STRING: ENSP00000257430
    BAP1Q925603, ENSP000004171324I2D: score=2 STRING: ENSP00000417132
    NFKBIEO002213, ENSP000002750154I2D: score=1 STRING: ENSP00000275015
    SLX4Q8IY923, ENSP000002940084I2D: score=1 STRING: ENSP00000294008
    NOD2Q9HC292MINT-8428233
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001955blood vessel maturation IEA--
    GO:0016032viral process IEA--
    GO:0019048modulation by virus of host morphology or physiology ----
    GO:0051151negative regulation of smooth muscle cell differentiation IEA--

    Find genes that share ontologies with ANKRD17           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKRD17 (ANR17)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ANKRD17 gene (3 alternative transcripts): 
    NM_001286771.1  NM_032217.3  NM_198889.1  

    Unigene Cluster for ANKRD17:

    Ankyrin repeat domain 17
    Hs.601206  [show with all ESTs]
    Unigene Representative Sequence: NM_032217
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358602(uc003hgo.3 uc003hgp.3 uc003hgq.3 uc003hgr.3)
    ENST00000558247 ENST00000509867 ENST00000330838 ENST00000510127 ENST00000513908
    ENST00000560507 ENST00000561029 ENST00000560372 ENST00000514252(uc011cbd.1)
    ENST00000559367
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ANKRD17 (see all 85):
    hsa-miR-411* hsa-miR-548j hsa-miR-199a-3p hsa-miR-30d hsa-miR-342-3p hsa-miR-30a hsa-miR-3122 hsa-miR-548a-5p
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      QuantiFast Probe-based Assays in human, mouse, rat ANKRD17

    Additional mRNA sequence: 

    AB014597.2 AF308285.1 AK025859.1 AK055209.1 AK096518.1 AK299046.1 AK300302.1 AK307581.1 
    AL831903.1 AL833287.1 BC004173.2 BC004891.2 BC007747.2 BC009043.1 BC019963.2 BC029935.2 
    BC043394.1 BX648035.1 

    20 DOTS entries:

    DT.101984779  DT.91760510  DT.447896  DT.95078546  DT.121250279  DT.100793373  DT.121250266  DT.121250224 
    DT.95314995  DT.100793377  DT.95147400  DT.91760507  DT.100030079  DT.100030080  DT.97764078  DT.121250252 
    DT.40108151  DT.446612  DT.86839944  DT.91937064 

    Selected AceView cDNA sequences (see all 351):

    BM460029 BC029935 BM975325 AI699876 AA046230 AI245175 BC043394 BU685163 
    BU687888 AI554864 AW629360 BQ887291 BM463945 AA653516 BG546441 BE219114 
    AL531141 AW958118 BM835201 BM987180 AI358443 BU620922 CD722926 AB014597 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD17 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^
    SP1:              -                                                                                                                                             
    SP2:                                                                                                                                                            
    SP3:                                                                                                  -     -                                                   
    SP4:              -                                                                                                                                             
    SP5:                                                                                                        -     -                                             

    ExUns: 24 ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29 ^ 30 ^ 31a · 31b ^ 32 ^ 33 ^ 34 ^ 35a · 35b
    SP1:                                                                                          
    SP2:                                                                                          
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for ANKRD17

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANKRD17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANKRD17 Expression
    About this image


    ANKRD17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             Testis Somatic Cells Primitive Gonad
     
     Gonad (Reproductive System)
             Testis Somatic Cells Primitive Gonad
    ANKRD17 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANKRD17 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.601206

    UniProtKB/Swiss-Prot: ANR17_HUMAN, O75179
    Tissue specificity: Expressed in bone marrow

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ANKRD17 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd171 , 5 ankyrin repeat domain 171, 5 92.9(n)1
    96.47(a)1
      5 (44.32 cM)5
    817021  NM_030886.21  NP_112148.21 
     902271905 
    chicken
    (Gallus gallus)
    Aves ANKRD171 ankyrin repeat domain 17 84.48(n)
    93.55(a)
      422651  XM_004941181.1  XP_004941238.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD176
    ankyrin repeat domain 17
    88(a)
    1 ↔ 1
    6(59878336-59942567)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.155992 Transcribed sequence with moderate similarity to protein more 85.77(n)    BX683411.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mask6
    multiple ankyrin repeats single KH domain
    28(a)
    1 → many
    3R(20056284-20075970)


    ENSEMBL Gene Tree for ANKRD17 (if available)
    TreeFam Gene Tree for ANKRD17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANKRD17 gene
    TANC22  ANKS32  ANKRD292  FEM1A2  ANKHD12  FANK12  KIDINS2202  ANKHD1-EIF4EBP32  
    FEM1B2  TANC12  ANKS62  FEM1C2  
    14 SIMAP similar genes for ANKRD17 using alignment to 5 protein entries:     ANR17_HUMAN (see all proteins):
    FLJ00246    ANKHD1    NOVA1    DKFZp586G1024    PPP1R12A    ACAP3
    ANKRD29    IkBa    PSMD10    ANKDD1A    DKFZp434B2328    GABPB1
    DKFZp761E1322    MTPN

    Find genes that share paralogs with ANKRD17           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANKRD17 (see all 3034)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829739121,2
    --73940061(+) AAAAAA/CTTTTA 2 -- ds50010--------
    rs1876050701,2
    --73940104(+) ACTTCA/GTTAAA 2 -- ds50010--------
    rs1486346211,2
    --73940136(+) TTAGTA/GAAGTG 2 -- ds50010--------
    rs1929382061,2
    --73940312(+) GAGAAA/GTCATC 2 -- ds50010--------
    rs117279571,2
    C,F,H--73940465(+) GAAATA/TTTATG 2 -- ds500111Minor allele frequency- N:0.00EA NA WA 760
    rs1437882941,2
    C--73940477(+) TAATT-/AAAAAA 2 -- ds50010--------
    rs1847269261,2
    --73940513(+) TTACTC/TGATTT 2 -- ut310--------
    rs1895965531,2
    --73940728(+) GTCTAC/TCATAA 2 -- ut310--------
    rs100921,2
    C,F,H--73940743(-) TGTCAC/TGAAGA 2 -- ut31 ese317Minor allele frequency- T:0.17MN NS EA NA 2010
    rs587991461,2
    C--73941090(+) GATGGC/TCCATC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ANKRD17 (73939093 - 74124515 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ANKRD17:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv5634n71CNV Loss21882294
    dgv5635n71CNV Loss21882294
    nsv523169CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKRD17
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKRD17

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for ANKRD17:    
    About MalaCards
    hand, foot and mouth disease    breast cancer

    1 disease from the University of Copenhagen DISEASES database for ANKRD17:
    hand, foot and mouth disease

    Find genes that share disorders with ANKRD17           About GenesLikeMe

    Genetic Association Database (GAD): ANKRD17
    Human Genome Epidemiology (HuGE) Navigator: ANKRD17 (2 documents)

    Export disorders for ANKRD17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANKRD17 gene, integrated from 10 sources (see all 43):
    (articles sorted by number of sources associating them with ANKRD17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm. (PubMed id 11165478)1, 3 Watt A.J....Forrester L.M. (Mech. Dev. 2001)
    4. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. (PubMed id 12747765)1, 2 Scanlan M.J.... Old L.J. (Cancer Immun. 2001)
    5. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (DNA Res. 1998)
    6. A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses. (PubMed id 23711367)1 Menning M. and Kufer T.A. (FEBS Lett. 2013)
    7. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    8. Proteomic analysis of I+4I^1 integrin adhesion complexes reveals I+-subunit-dependent protein recruitment. (PubMed id 22623428)1 Byron A....Humphries M.J. (Proteomics 2012)
    9. Ankrd17 positively regulates RIG-I-like receptor (RLR)-mediated immune signaling. (PubMed id 22328336)1 Wang Y....Ye X. (Eur. J. Immunol. 2012)
    10. Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks. (PubMed id 22558309)1 Wong K.A....O'Bryan J.P. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26057 HGNC: 23575 AceView: ANKRD17 Ensembl:ENSG00000132466 euGenes: HUgn26057
    ECgene: ANKRD17 H-InvDB: ANKRD17

    (According to HUGE)
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    HUGE: KIAA0697

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANKRD17 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ANKRD17 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANKRD17 gene:
    Search GeneIP for patents involving ANKRD17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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