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Aliases for ANKRD16 Gene

Aliases for ANKRD16 Gene

  • Ankyrin Repeat Domain 16 2 3 5

External Ids for ANKRD16 Gene

Previous GeneCards Identifiers for ANKRD16 Gene

  • GC10M005907
  • GC10M005942
  • GC10M005905
  • GC10M005906
  • GC10M005830
  • GC10M005909
  • GC10M005911
  • GC10M005912
  • GC10M005914
  • GC10M005916
  • GC10M005918
  • GC10M005920

Summaries for ANKRD16 Gene

GeneCards Summary for ANKRD16 Gene

ANKRD16 (Ankyrin Repeat Domain 16) is a Protein Coding gene. An important paralog of this gene is FEM1B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD16 Gene

Genomics for ANKRD16 Gene

Regulatory Elements for ANKRD16 Gene

Promoters for ANKRD16 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD16 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD16 Gene

5,861,617 bp from pter
5,889,906 bp from pter
28,290 bases
Minus strand

Genomic View for ANKRD16 Gene

Genes around ANKRD16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD16 Gene

Proteins for ANKRD16 Gene

  • Protein details for ANKRD16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 16
    Protein Accession:
    Secondary Accessions:
    • A6NEF0
    • F8WEI4
    • Q9NT01

    Protein attributes for ANKRD16 Gene

    361 amino acids
    Molecular mass:
    39284 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD16 Gene


neXtProt entry for ANKRD16 Gene

Proteomics data for ANKRD16 Gene at MOPED

Post-translational modifications for ANKRD16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD16 Gene

No data available for DME Specific Peptides for ANKRD16 Gene

Domains & Families for ANKRD16 Gene

Gene Families for ANKRD16 Gene

Protein Domains for ANKRD16 Gene

Suggested Antigen Peptide Sequences for ANKRD16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 9 ANK repeats.
  • Contains 9 ANK repeats.
genes like me logo Genes that share domains with ANKRD16: view

Function for ANKRD16 Gene

genes like me logo Genes that share phenotypes with ANKRD16: view

Animal Model Products

CRISPR Products

miRNA for ANKRD16 Gene

miRTarBase miRNAs that target ANKRD16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD16 Gene

Localization for ANKRD16 Gene

Subcellular locations from

Jensen Localization Image for ANKRD16 Gene COMPARTMENTS Subcellular localization image for ANKRD16 gene
Compartment Confidence
cytosol 3
nucleus 3
extracellular 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD16 Gene

Pathways & Interactions for ANKRD16 Gene

SuperPathways for ANKRD16 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD16 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD16 Gene

Drugs & Compounds for ANKRD16 Gene

No Compound Related Data Available

Transcripts for ANKRD16 Gene

Unigene Clusters for ANKRD16 Gene

Ankyrin repeat domain 16:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD16 Gene

No ASD Table

Relevant External Links for ANKRD16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD16 Gene

mRNA expression in normal human tissues for ANKRD16 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ANKRD16 Gene

This gene is overexpressed in Platelet (42.4) and Bone (20.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ANKRD16 Gene

SOURCE GeneReport for Unigene cluster for ANKRD16 Gene Hs.289828

genes like me logo Genes that share expression patterns with ANKRD16: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ANKRD16 Gene

Orthologs for ANKRD16 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD16 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD16 35
  • 82.78 (n)
  • 83.61 (a)
ANKRD16 36
  • 81 (a)
(Canis familiaris)
Mammalia ANKRD16 35
  • 78.41 (n)
  • 77.27 (a)
ANKRD16 36
  • 77 (a)
(Mus musculus)
Mammalia Ankrd16 35
  • 82.54 (n)
  • 82.63 (a)
Ankrd16 16
Ankrd16 36
  • 82 (a)
(Pan troglodytes)
Mammalia ANKRD16 35
  • 99.54 (n)
  • 99.45 (a)
ANKRD16 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ankrd16 35
  • 82.44 (n)
  • 82.44 (a)
(Monodelphis domestica)
Mammalia ANKRD16 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD16 36
  • 68 (a)
(Gallus gallus)
Aves ANKRD16 35
  • 69.66 (n)
  • 69.86 (a)
ANKRD16 36
  • 64 (a)
(Anolis carolinensis)
Reptilia ANKRD16 36
  • 64 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd16 35
  • 64.35 (n)
  • 61.56 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.14968 35
(Danio rerio)
Actinopterygii ankrd16 35
  • 62.36 (n)
  • 60.96 (a)
ankrd16 36
  • 58 (a)
fruit fly
(Drosophila melanogaster)
Insecta pain 36
  • 7 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 38 (a)
Species with no ortholog for ANKRD16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD16 Gene

Gene Tree for ANKRD16 (if available)
Gene Tree for ANKRD16 (if available)

Paralogs for ANKRD16 Gene

Paralogs for ANKRD16 Gene

(4) SIMAP similar genes for ANKRD16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD16: view

Variants for ANKRD16 Gene

Sequence variations from dbSNP and Humsavar for ANKRD16 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1052420 - 5,878,158(-) CCTTC(A/G)GGGCT reference, missense, utr-variant-3-prime
VAR_033503 -
rs599394 -- 5,880,592(+) GGAGG(C/G)TATGG intron-variant
rs600706 -- 5,880,852(+) TCTTA(A/C)GTTTT intron-variant
rs603780 -- 5,882,259(+) AACAA(A/G)TAggc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD16 Gene

Variant ID Type Subtype PubMed ID
dgv1e49 CNV Loss 18971310
nsv831775 CNV Loss 17160897
nsv5654 CNV Loss 18451855
nsv825229 CNV Gain 20364138
nsv437655 CNV Loss 16327808
nsv520941 CNV Loss 19592680
esv2676037 CNV Deletion 23128226
nsv519773 CNV Loss 19592680
esv2668731 CNV Deletion 23128226

Variation tolerance for ANKRD16 Gene

Residual Variation Intolerance Score: 82% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.97; 79.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD16 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD16 Gene

Disorders for ANKRD16 Gene

Relevant External Links for ANKRD16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD16 Gene

Publications for ANKRD16 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Genome-wide association study identifies five new breast cancer susceptibility loci. (PMID: 20453838) Turnbull C. … Easton D.F. (Nat. Genet. 2010) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ANKRD16 Gene

Sources for ANKRD16 Gene

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