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Aliases for ANKRD13C Gene

Aliases for ANKRD13C Gene

  • Ankyrin Repeat Domain 13C 2 3 5
  • DJ677H15.3 3

External Ids for ANKRD13C Gene

Previous GeneCards Identifiers for ANKRD13C Gene

  • GC01M070439
  • GC01M070500
  • GC01M070724
  • GC01M068835

Summaries for ANKRD13C Gene

GeneCards Summary for ANKRD13C Gene

ANKRD13C (Ankyrin Repeat Domain 13C) is a Protein Coding gene. GO annotations related to this gene include receptor binding. An important paralog of this gene is ANKRD13D.

UniProtKB/Swiss-Prot for ANKRD13C Gene

  • Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.

Gene Wiki entry for ANKRD13C Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD13C Gene

Genomics for ANKRD13C Gene

Regulatory Elements for ANKRD13C Gene

Enhancers for ANKRD13C Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ANKRD13C on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD13C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD13C on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD13C Gene

70,259,002 bp from pter
70,354,788 bp from pter
95,787 bases
Minus strand

Genomic View for ANKRD13C Gene

Genes around ANKRD13C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD13C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD13C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD13C Gene

Proteins for ANKRD13C Gene

  • Protein details for ANKRD13C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 13C
    Protein Accession:
    Secondary Accessions:
    • B3KQ97
    • Q5VYH4
    • Q5VYH5
    • Q6PJE4
    • Q9H0N9

    Protein attributes for ANKRD13C Gene

    541 amino acids
    Molecular mass:
    60818 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG51959.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD13C Gene


neXtProt entry for ANKRD13C Gene

Proteomics data for ANKRD13C Gene at MOPED

Post-translational modifications for ANKRD13C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD13C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD13C Gene

Domains & Families for ANKRD13C Gene

Gene Families for ANKRD13C Gene

Protein Domains for ANKRD13C Gene

Suggested Antigen Peptide Sequences for ANKRD13C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 ANK repeats.
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with ANKRD13C: view

Function for ANKRD13C Gene

Molecular function for ANKRD13C Gene

UniProtKB/Swiss-Prot Function:
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
genes like me logo Genes that share phenotypes with ANKRD13C: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD13C Gene

Localization for ANKRD13C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANKRD13C Gene

Endoplasmic reticulum membrane. Note=Associated with the cytosolic side.

Subcellular locations from

Jensen Localization Image for ANKRD13C Gene COMPARTMENTS Subcellular localization image for ANKRD13C gene
Compartment Confidence
endoplasmic reticulum 5
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for ANKRD13C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0048471 perinuclear region of cytoplasm IDA 20959461
genes like me logo Genes that share ontologies with ANKRD13C: view

Pathways & Interactions for ANKRD13C Gene

SuperPathways for ANKRD13C Gene

No Data Available

Interacting Proteins for ANKRD13C Gene

Gene Ontology (GO) - Biological Process for ANKRD13C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006621 protein retention in ER lumen IMP 20959461
genes like me logo Genes that share ontologies with ANKRD13C: view

No data available for Pathways by source and SIGNOR curated interactions for ANKRD13C Gene

Drugs & Compounds for ANKRD13C Gene

No Compound Related Data Available

Transcripts for ANKRD13C Gene

Unigene Clusters for ANKRD13C Gene

Ankyrin repeat domain 13C:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD13C Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c
SP2: - - - - - - -
SP3: -
SP4: - -

Relevant External Links for ANKRD13C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD13C Gene

mRNA expression in normal human tissues for ANKRD13C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ANKRD13C Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (58.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ANKRD13C Gene

SOURCE GeneReport for Unigene cluster for ANKRD13C Gene Hs.744989

genes like me logo Genes that share expression patterns with ANKRD13C: view

Protein tissue co-expression partners for ANKRD13C Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD13C Gene

Orthologs for ANKRD13C Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD13C Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ANKRD13C 35
  • 95.37 (n)
  • 99.23 (a)
  • 99 (a)
(Mus musculus)
Mammalia Ankrd13c 35
  • 88.74 (n)
  • 92.72 (a)
Ankrd13c 16
Ankrd13c 36
  • 92 (a)
(Pan troglodytes)
Mammalia ANKRD13C 35
  • 99.75 (n)
  • 99.82 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Ankrd13c 35
  • 88.97 (n)
  • 93.08 (a)
(Bos Taurus)
Mammalia ANKRD13C 36
  • 96 (a)
(Monodelphis domestica)
Mammalia ANKRD13C 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD13C 36
  • 98 (a)
(Gallus gallus)
Aves ANKRD13C 35
  • 89.55 (n)
  • 96.67 (a)
  • 96 (a)
(Anolis carolinensis)
Reptilia ANKRD13C 36
  • 96 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd13c 35
  • 79.09 (n)
  • 89.94 (a)
Str.8944 35
African clawed frog
(Xenopus laevis)
Amphibia MGC53218 35
(Danio rerio)
Actinopterygii ankrd13c 35
  • 74.25 (n)
  • 88.11 (a)
wufc57c01 35
ankrd13c 36
  • 88 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10323 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009954 35
  • 58.95 (n)
  • 66.32 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5742 35
  • 55.43 (n)
  • 55.96 (a)
CG5742 36
  • 47 (a)
(Caenorhabditis elegans)
Secernentea C01F1.6 35
  • 56.07 (n)
  • 51.64 (a)
C01F1.6 36
  • 50 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6516 36
  • 46 (a)
Species with no ortholog for ANKRD13C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD13C Gene

Gene Tree for ANKRD13C (if available)
Gene Tree for ANKRD13C (if available)

Paralogs for ANKRD13C Gene

Paralogs for ANKRD13C Gene

(4) SIMAP similar genes for ANKRD13C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD13C: view

Variants for ANKRD13C Gene

Sequence variations from dbSNP and Humsavar for ANKRD13C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs17852616 - 70,276,823(+) AGGTG(A/T)AAGAG reference, missense
rs156107 -- 70,261,114(-) GAATT(C/T)TGGGG utr-variant-3-prime
rs190607 -- 70,277,107(+) TTTTA(A/C/G/T)ATGAT intron-variant
rs269271 -- 70,272,175(-) TTCAG(A/G)AAAAA intron-variant
rs269272 -- 70,271,977(-) AGAAT(C/T)GATGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD13C Gene

Variant ID Type Subtype PubMed ID
nsv871430 CNV Loss 21882294
nsv830137 CNV Loss 17160897
esv2555384 CNV Deletion 19546169
esv1997734 CNV Deletion 18987734
esv4055 CNV Deletion 18987735
esv2749597 CNV Deletion 23290073
esv2657438 CNV Deletion 23128226

Variation tolerance for ANKRD13C Gene

Residual Variation Intolerance Score: 19.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.67; 14.29% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ANKRD13C Gene

Disorders for ANKRD13C Gene

Relevant External Links for ANKRD13C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD13C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD13C Gene

Publications for ANKRD13C Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. (PMID: 25011556) Wagner T.A. … Frenkel L.M. (Science 2014) 3
  4. HIV/AIDS. Persistence by proliferation? (PMID: 25013050) Margolis D. … Bushman F. (Science 2014) 3
  5. Inverse agonist and pharmacochaperone properties of MK-0524 on the prostanoid DP1 receptor. (PMID: 23762421) Labrecque P. … Parent J.L. (PLoS ONE 2013) 3

Products for ANKRD13C Gene

Sources for ANKRD13C Gene