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Aliases for ANKRD13C Gene

Aliases for ANKRD13C Gene

  • Ankyrin Repeat Domain 13C 2 3
  • Ankyrin Repeat Domain-Containing Protein 13C 3
  • DJ677H15.3 3

External Ids for ANKRD13C Gene

Previous GeneCards Identifiers for ANKRD13C Gene

  • GC01M070439
  • GC01M070500
  • GC01M070724
  • GC01M068835

Summaries for ANKRD13C Gene

GeneCards Summary for ANKRD13C Gene

ANKRD13C (Ankyrin Repeat Domain 13C) is a Protein Coding gene. GO annotations related to this gene include receptor binding. An important paralog of this gene is ANKRD13D.

UniProtKB/Swiss-Prot for ANKRD13C Gene

  • Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.

Gene Wiki entry for ANKRD13C Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD13C Gene

Genomics for ANKRD13C Gene

Regulatory Elements for ANKRD13C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ANKRD13C Gene

70,259,002 bp from pter
70,354,788 bp from pter
95,787 bases
Minus strand

Genomic View for ANKRD13C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD13C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD13C Gene

Proteins for ANKRD13C Gene

  • Protein details for ANKRD13C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 13C
    Protein Accession:
    Secondary Accessions:
    • B3KQ97
    • Q5VYH4
    • Q5VYH5
    • Q6PJE4
    • Q9H0N9

    Protein attributes for ANKRD13C Gene

    541 amino acids
    Molecular mass:
    60818 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG51959.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ANKRD13C Gene


neXtProt entry for ANKRD13C Gene

Proteomics data for ANKRD13C Gene at MOPED

Post-translational modifications for ANKRD13C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD13C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD13C Gene

Domains for ANKRD13C Gene

Gene Families for ANKRD13C Gene

  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD13C Gene

Suggested Antigen Peptide Sequences for ANKRD13C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N6S4
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with ANKRD13C: view

Function for ANKRD13C Gene

Molecular function for ANKRD13C Gene

UniProtKB/Swiss-Prot Function: Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.

Gene Ontology (GO) - Molecular Function for ANKRD13C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005102 receptor binding IPI 20959461
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD13C: view

Phenotypes for ANKRD13C Gene

GenomeRNAi human phenotypes for ANKRD13C:
genes like me logo Genes that share phenotypes with ANKRD13C: view

Animal Model Products

CRISPR Products

miRNA for ANKRD13C Gene

miRTarBase miRNAs that target ANKRD13C

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD13C

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ANKRD13C Gene

Localization for ANKRD13C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANKRD13C Gene

Endoplasmic reticulum membrane. Note=Associated with the cytosolic side.

Subcellular locations from

Jensen Localization Image for ANKRD13C Gene COMPARTMENTS Subcellular localization image for ANKRD13C gene
Compartment Confidence
endoplasmic reticulum 5
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for ANKRD13C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 colocalizes_with endoplasmic reticulum IDA 20959461
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016020 membrane --
GO:0048471 perinuclear region of cytoplasm IDA 20959461
genes like me logo Genes that share ontologies with ANKRD13C: view

Pathways for ANKRD13C Gene

SuperPathways for ANKRD13C Gene

No Data Available

Interacting Proteins for ANKRD13C Gene

Gene Ontology (GO) - Biological Process for ANKRD13C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006621 protein retention in ER lumen IMP 20959461
GO:0010869 regulation of receptor biosynthetic process IDA 20959461
GO:2000209 regulation of anoikis IDA 20959461
genes like me logo Genes that share ontologies with ANKRD13C: view

No data available for Pathways by source for ANKRD13C Gene

Transcripts for ANKRD13C Gene

Unigene Clusters for ANKRD13C Gene

Ankyrin repeat domain 13C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD13C

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD13C Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c
SP2: - - - - - - -
SP3: -
SP4: - -

Relevant External Links for ANKRD13C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD13C Gene

mRNA expression in normal human tissues for ANKRD13C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ANKRD13C Gene

SOURCE GeneReport for Unigene cluster for ANKRD13C Gene Hs.744989

genes like me logo Genes that share expressions with ANKRD13C: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD13C Gene

Orthologs for ANKRD13C Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD13C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANKRD13C 35
  • 99.75 (n)
  • 99.82 (a)
  • 100 (a)
(Bos Taurus)
Mammalia ANKRD13C 36
  • 96 (a)
(Canis familiaris)
Mammalia ANKRD13C 35
  • 95.37 (n)
  • 99.23 (a)
  • 99 (a)
(Mus musculus)
Mammalia Ankrd13c 35
  • 88.74 (n)
  • 92.72 (a)
Ankrd13c 16
Ankrd13c 36
  • 92 (a)
(Monodelphis domestica)
Mammalia ANKRD13C 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD13C 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Ankrd13c 35
  • 88.97 (n)
  • 93.08 (a)
(Gallus gallus)
Aves ANKRD13C 35
  • 89.55 (n)
  • 96.67 (a)
  • 96 (a)
(Anolis carolinensis)
Reptilia ANKRD13C 36
  • 96 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC53218 35
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd13c 35
  • 79.09 (n)
  • 89.94 (a)
Str.8944 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10323 35
(Danio rerio)
Actinopterygii ankrd13c 35
  • 74.25 (n)
  • 88.11 (a)
ankrd13c 36
  • 88 (a)
wufc57c01 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009954 35
  • 58.95 (n)
  • 66.32 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5742 35
  • 55.43 (n)
  • 55.96 (a)
CG5742 36
  • 47 (a)
(Caenorhabditis elegans)
Secernentea C01F1.6 35
  • 56.07 (n)
  • 51.64 (a)
C01F1.6 36
  • 50 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6516 36
  • 46 (a)
Species with no ortholog for ANKRD13C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD13C Gene

Gene Tree for ANKRD13C (if available)
Gene Tree for ANKRD13C (if available)

Paralogs for ANKRD13C Gene

Paralogs for ANKRD13C Gene

Selected SIMAP similar genes for ANKRD13C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD13C: view

Variants for ANKRD13C Gene

Sequence variations from dbSNP and Humsavar for ANKRD13C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs156107 -- 70,261,114(-) GAATT(C/T)TGGGG utr-variant-3-prime
rs190607 -- 70,277,107(-) TTTTA(G/T)ATGAT intron-variant
rs269271 -- 70,272,175(-) TTCAG(A/G)AAAAA intron-variant
rs269272 -- 70,271,977(-) AGAAT(C/T)GATGT intron-variant
rs269273 -- 70,268,504(-) TATTA(C/T)GGATC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD13C Gene

Variant ID Type Subtype PubMed ID
nsv871430 CNV Loss 21882294
nsv830137 CNV Loss 17160897
esv2555384 CNV Deletion 19546169
esv1997734 CNV Deletion 18987734
esv4055 CNV Deletion 18987735
esv2749597 CNV Deletion 23290073
esv2657438 CNV Deletion 23128226

Relevant External Links for ANKRD13C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD13C Gene

Disorders for ANKRD13C Gene

No disorders were found for ANKRD13C Gene.

No data available for UniProtKB/Swiss-Prot for ANKRD13C Gene

Publications for ANKRD13C Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. ANKRD13C acts as a molecular Chaperone for G protein-coupled receptors. (PMID: 20959461) Parent A. … Parent J.L. (J. Biol. Chem. 2010) 3 4

Products for ANKRD13C Gene

Sources for ANKRD13C Gene

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