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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKRD11 Gene

protein-coding   GIFtS: 51
GCID: GC16M089334

Ankyrin Repeat Domain 11

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat Domain 111 2     LZ162
ANCO12 3 5     T132
Ankyrin Repeat-Containing Cofactor 12 3     Ankyrin Repeat Domain-Containing Protein 112
ANCO-12     Nasopharyngeal Carcinoma Susceptibility Protein2

External Ids:    HGNC: 213161   Entrez Gene: 291232   Ensembl: ENSG000001675227   OMIM: 6111925   UniProtKB: Q6UB993   

Export aliases for ANKRD11 gene to outside databases

Previous GC identifers: GC16M089095 GC16M089077 GC16M087861 GC16M075032


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANKRD11 Gene:
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent
activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is
characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global
developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been
described. Related pseudogenes exist on chromosomes 2 and X. (provided by RefSeq, Jan 2012)

GeneCards Summary for ANKRD11 Gene: 
ANKRD11 (ankyrin repeat domain 11) is a protein-coding gene. Diseases associated with ANKRD11 include kbg syndrome, and epidural neoplasm. An important paralog of this gene is BARD1.

UniProtKB/Swiss-Prot: ANR11_HUMAN, Q6UB99
Function: May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent
transactivation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010542.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANKRD11 gene promoter:
         Pax-5   AP-1   ATF-2   ARP-1   c-Jun   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ANKRD11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3   Ensembl cytogenetic band:  16q24.3   HGNC cytogenetic band: 16q24.3

ANKRD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD11 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M089334:  view genomic region     (about GC identifiers)

Start:
89,334,035 bp from pter      End:
89,556,969 bp from pter
Size:
222,935 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANR11_HUMAN, Q6UB99 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 11  
Size: 2663 amino acids; 297913 Da
Subunit: Interacts with the PAS region of the p160 coactivators
Subcellular location: Nucleus
Sequence caution: Sequence=AAH69013.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q6NTG1 Q6QMF8

Explore the universe of human proteins at neXtProt for ANKRD11: NX_Q6UB99

Explore proteomics data for ANKRD11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6UB99

  • ANKRD11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANKRD11 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001243111.1  NP_001243112.1  NP_037407.4  

    ENSEMBL proteins: 
     ENSP00000367581   ENSP00000301030   ENSP00000330815   ENSP00000458043   ENSP00000454550  
     ENSP00000367583   ENSP00000455008  

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    Cloud-Clone Corp. Proteins for ANKRD11 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    ANKRD11 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    2 InterPro protein domains:
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q6UB99

    ProtoNet protein and cluster: Q6UB99

    1 Blocks protein domain: IPB002110 Ankyrin repeat signature

    UniProtKB/Swiss-Prot: ANR11_HUMAN, Q6UB99
    Similarity: Contains 4 ANK repeats


    ANKRD11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANR11_HUMAN, Q6UB99
    Function: May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent
    transactivation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    ANKRD11 for ontologies           About GeneDecksing


    Phenotypes:
         12 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ankrd11):
     behavior/neurological  cardiovascular system  craniofacial  embryogenesis  growth/size 
     hematopoietic system  homeostasis/metabolism  immune system  mortality/aging  other 
     skeleton  vision/eye 

    ANKRD11 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKRD11 
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    SwitchGear 3'UTR luciferase reporter plasmidANKRD11 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for ANKRD11 (Q6UB993 ENSP000003010304) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCOA2Q155963, ENSP000003999684I2D: score=3 STRING: ENSP00000399968
    HDAC4P565243, ENSP000002646064I2D: score=1 STRING: ENSP00000264606
    HDAC3O153793, ENSP000003029674I2D: score=3 STRING: ENSP00000302967
    HDAC5Q9UQL63, ENSP000002259834I2D: score=1 STRING: ENSP00000225983
    NCOA3Q9Y6Q93, ENSP000003610664I2D: score=1 STRING: ENSP00000361066
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--
    GO:0001894tissue homeostasis IEA--
    GO:0035264multicellular organism growth IEA--
    GO:0042475odontogenesis of dentin-containing tooth IMP--
    GO:0048705skeletal system morphogenesis IMP--

    ANKRD11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANKRD11 (ANR11)

    Search CenterWatch for drugs/clinical trials and news about ANKRD11 / ANR11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANKRD11 gene (3 alternative transcripts): 
    NM_001256182.1  NM_001256183.1  NM_013275.5  

    Unigene Cluster for ANKRD11:

    Ankyrin repeat domain 11
    Hs.740440  [show with all ESTs]
    Unigene Representative Sequence: NM_001256182
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378330 ENST00000301030(uc002fmx.1 uc002fmy.1 uc002fnc.1)
    ENST00000330736(uc002fnb.1) ENST00000562194 ENST00000568100 ENST00000562275(uc002fnd.3)
    ENST00000378332(uc002fne.3) ENST00000564553 ENST00000562816 ENST00000567736(uc002fnf.1 uc002fng.1)
    ENST00000568924 ENST00000563291 ENST00000566858 ENST00000567699 ENST00000568512
    ENST00000566973
    miRNA
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    hsa-miR-136 hsa-miR-548k hsa-let-7a-2* hsa-miR-383 hsa-miR-4330 hsa-miR-497* hsa-miR-365 hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidANKRD11 3' UTR sequence
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    Additional mRNA sequence: 

    AB209186.1 AF121775.1 AF130076.1 AK025964.1 AK057803.1 AK092264.1 AK093762.1 AK125549.1 
    AK290994.1 AY131227.1 AY373756.1 AY533563.1 AY726574.1 BC007975.2 BC017437.1 BC025283.1 
    BC031340.1 BC041059.1 BC041585.1 BC052290.1 BC058001.1 BC069013.1 NR_045839.1 

    24/25 DOTS entries (see all 25):

    DT.95280024  DT.95075020  DT.97788102  DT.92432478  DT.91750084  DT.309239  DT.91840739  DT.120671673 
    DT.40269772  DT.455042  DT.95369539  DT.121290894  DT.95083943  DT.99994625  DT.95083412  DT.87046996 
    DT.99968057  DT.100686841  DT.102838942  DT.65285806  DT.95259350  DT.95369540  DT.99965989  DT.75129992 

    24/354 AceView cDNA sequences (see all 354):

    BC025283 AA806298 BU790192 BG258079 CB155647 CK822194 CA430140 AL526386 
    CF127062 CK822195 BQ930336 AI684375 AI493451 AA865761 BE909024 AI829801 
    AW874083 AW149767 AI809857 AW452846 BE208796 AA581361 AA838844 CA446445 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD11 (see all 13)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15a ·
    SP1:                    -     -     -                       -           -     -     -     -     -     -     -                       -     -     -               
    SP2:                    -     -     -                       -           -     -     -     -     -     -     -                       -     -     -               
    SP3:                                                        -           -     -     -     -     -                                                               
    SP4:                                                                                                                                -     -     -               
    SP5:                                                        -           -     -     -     -     -     -     -                                                   

    ExUns: 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for ANKRD11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKRD11 expression in normal human tissues (normalized intensities)      ANKRD11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGCTGACA
    ANKRD11 Expression
    About this image


    ANKRD11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/33 selected tissues (see all 33) fully expand
     
     Epithelium (Reproductive System)    fully expand to see all 5 entries
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See ANKRD11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANKRD11

    SOURCE GeneReport for Unigene cluster: Hs.740440
        SABiosciences Custom PCR Arrays for ANKRD11
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ANKRD11 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd111 , 5 ankyrin repeat domain 111, 5 79.89(n)1
    81.03(a)1
      8 (72.00 cM)5
    770871  NM_001081379.21  NP_001074848.21 
     1228833375 
    chicken
    (Gallus gallus)
    Aves ANKRD111 ankyrin repeat domain 11 73.61(n)
    71.53(a)
      415845  XM_414205.3  XP_414205.3 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD116
    ankyrin repeat domain 11
    66(a)
    1 ↔ 1
    GL343487.1(265378-319310)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.238202 Xenopus laevis transcribed sequence with strong similarity more 75.86(n)    CB941509.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi04c062 Transcribed sequence with weak similarity to protein more 73.94(n)    57062649 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG109846
    --
    18(a)
    1 → many
    3L(12743219-12746502)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HOS46
    Subunit of the Set3 complex, which is a meiotic-sp...
    11(a)
    1 → many
    IX(151595-154846)


    ENSEMBL Gene Tree for ANKRD11 (if available)
    TreeFam Gene Tree for ANKRD11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKRD11 gene
    BARD12  BCOR2  TONSL2  ANKRD322  ANKRD122  ANKRD312  BCORL12  
    6 SIMAP similar genes for ANKRD11 using alignment to 9 protein entries:     ANR11_HUMAN (see all proteins):
    ANKRD12    OSBPL1A    PPP1R12A    PPP1R27    DKFZp761E1322    MTPN

    ANKRD11 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for ANKRD11
    PGOHUM00000240111 PGOHUM00000262437 PGOHUM00000235167 PGOHUM00000241588


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5694 SNPs in ANKRD11 are shown (see all 5694)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509546801,2
    --75031830(+) CCTCCG/TCAGGG 3 -- int10--------
    rs1863064781,2
    --75031964(+) GGAAAA/GGGGTG 3 -- int10--------
    rs1918084881,2
    --89333559(+) TGCTCC/TTGTTT 3 -- ds50010--------
    rs169646801,2
    C,F--89333575(+) CAGCTC/TCTACA 3 -- ds50014Minor allele frequency- T:0.02NA 262
    rs1166760711,2
    C,F--89333613(+) GTCTGT/AGCAAA 3 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1456318841,2
    C--89333628(+) GAGGAC/TGAGGG 3 -- ds50010--------
    rs1837617781,2
    C--89333663(+) AAAAGC/GTAACA 3 -- ds50010--------
    rs1144047001,2
    F--89333680(+) TAGGAA/TAAAGG 3 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1866044641,2
    --89333752(+) AGCCTC/GCACCT 3 -- ds50010--------
    rs1469901141,2
    C--89333764(+) CTGGGA/TTCAAA 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for ANKRD11 (89334035 - 89556969 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/67 variations for ANKRD11 (see all 67):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2665887CNV Deletion23128226
    esv2715156CNV Deletion23290073
    esv2715145CNV Deletion23290073
    esv1451902CNV Deletion17803354
    esv994831CNV Deletion20482838
    esv2715151CNV Deletion23290073
    esv2715143CNV Deletion23290073
    esv2662057CNV Deletion23128226
    esv2715158CNV Deletion23290073
    esv2715148CNV Deletion23290073


    Human Gene Mutation Database (HGMD): ANKRD11
    SABiosciences Cancer Mutation PCR Assays
    2 SABiosciences qBiomarker Copy Number PCR Arrays containing ANKRD11:
    Birth Defects
    Intellectual Disability
    SeqTarget long-range PCR primers for resequencing ANKRD11
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKRD11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611192    OMIM disorders: --

    UniProtKB/Swiss-Prot: ANR11_HUMAN, Q6UB99
  • KBG syndrome (KBGS) [MIM:148050]: A syndrome characterized by macrodontia of the upper central incisors,
    distinctive craniofacial findings, short stature, skeletal anomalies, and neurologic involvement that includes
    global developmental delay, seizures, and intellectual disability. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 7 diseases for ANKRD11:    About MalaCards
    kbg syndrome    epidural neoplasm    nasal cavity lymphoma    16q24.3 microdeletion syndrome
    nasopharyngitis    intellectual disability    short stature

    4 diseases from the University of Copenhagen DISEASES database for ANKRD11:
    KBG syndrome     Nasal cavity lymphoma     Carcinoma     Breast cancer

    ANKRD11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ANKRD11

    Export disorders for ANKRD11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKRD11 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with ANKRD11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia. (PubMed id 21782149)1, 2 Sirmaci A....Tekin M. (2011)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators. (PubMed id 15184363)1, 2 Zhang A....Chen J.D. (2004)
    5. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PubMed id 11483580)1, 3 Yu Y....He F. (2001)
    6. Identification of ANKRD11 as a p53 coactivator. (PubMed id 18840648)1, 9 Neilsen P.M....Callen D.F. (2008)
    7. Partial deletion of ANKRD11 results in the KBG phenoty pe distinct from the 16q24.3 microdeletion syndrome. (PubMed id 23494856)1 Khalifa M....Duby J. (2013)
    8. The CCND1 c.870G>A polymorphism is a risk factor fo r t(11;14)(q13;q32) multiple myeloma. (PubMed id 23502783)1 Weinhold N....Hemminki K. (2013)
    9. Neurobehavioral phenotype observed in KBG syndrome cau sed by ANKRD11 mutations. (PubMed id 23184435)1 Lo-Castro A....Curatolo P. (2013)
    10. The functional interactome landscape of the human hist one deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29123 HGNC: 21316 AceView: ANKRD11 Ensembl:ENSG00000167522 euGenes: HUgn29123
    ECgene: ANKRD11 H-InvDB: ANKRD11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKRD11 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ANKRD11 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKRD11 gene:
    Search GeneIP for patents involving ANKRD11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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