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Aliases for ANKRD10 Gene

Aliases for ANKRD10 Gene

  • Ankyrin Repeat Domain 10 2 3 5

External Ids for ANKRD10 Gene

Previous GeneCards Identifiers for ANKRD10 Gene

  • GC13M105918
  • GC13M110367
  • GC13M109228
  • GC13M110328
  • GC13M111530
  • GC13M092129

Summaries for ANKRD10 Gene

GeneCards Summary for ANKRD10 Gene

ANKRD10 (Ankyrin Repeat Domain 10) is a Protein Coding gene. An important paralog of this gene is ANKRD37.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD10 Gene

Genomics for ANKRD10 Gene

Regulatory Elements for ANKRD10 Gene

Promoters for ANKRD10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD10 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD10 Gene

Chromosome:
13
Start:
110,878,540 bp from pter
End:
110,915,107 bp from pter
Size:
36,568 bases
Orientation:
Minus strand

Genomic View for ANKRD10 Gene

Genes around ANKRD10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD10 Gene

Proteins for ANKRD10 Gene

  • Protein details for ANKRD10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NXR5-ANR10_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 10
    Protein Accession:
    Q9NXR5
    Secondary Accessions:
    • Q5VW12
    • Q9BV12

    Protein attributes for ANKRD10 Gene

    Size:
    420 amino acids
    Molecular mass:
    44768 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD10 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD10 Gene

Proteomics data for ANKRD10 Gene at MOPED

Post-translational modifications for ANKRD10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD10 Gene

No data available for DME Specific Peptides for ANKRD10 Gene

Domains & Families for ANKRD10 Gene

Gene Families for ANKRD10 Gene

Protein Domains for ANKRD10 Gene

Suggested Antigen Peptide Sequences for ANKRD10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NXR5

UniProtKB/Swiss-Prot:

ANR10_HUMAN :
  • Contains 4 ANK repeats.
Similarity:
  • Contains 4 ANK repeats.
genes like me logo Genes that share domains with ANKRD10: view

Function for ANKRD10 Gene

Phenotypes for ANKRD10 Gene

genes like me logo Genes that share phenotypes with ANKRD10: view

Animal Model Products

CRISPR Products

miRNA for ANKRD10 Gene

miRTarBase miRNAs that target ANKRD10

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD10 Gene

Localization for ANKRD10 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD10 Gene COMPARTMENTS Subcellular localization image for ANKRD10 gene
Compartment Confidence
cytosol 4
nucleus 3
cytoskeleton 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD10 Gene

Pathways & Interactions for ANKRD10 Gene

SuperPathways for ANKRD10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD10 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD10 Gene

Drugs & Compounds for ANKRD10 Gene

No Compound Related Data Available

Transcripts for ANKRD10 Gene

Unigene Clusters for ANKRD10 Gene

Ankyrin repeat domain 10:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD10 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d ·
SP1: - - - - - - - - - - - - -
SP2: - - - - - - - - - - -
SP3: - - - - - - - - - - -
SP4: - - - - - - - -
SP5: - - - - - - - - - - - -
SP6: - - - - - - - - - - -
SP7: - - - - - - - - - - -
SP8: - -
SP9: - - - - - - -
SP10: - - - - -
SP11: -
SP12: - - - -
SP13: - - - - - - - - - - - - - -
SP14: - - - - - - - - - - - - - - -
SP15:
SP16: -
SP17:

ExUns: 10e · 10f · 10g · 10h · 10i ^ 11a · 11b · 11c · 11d ^ 12a · 12b · 12c
SP1: - - - -
SP2: - - -
SP3:
SP4: - - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: - - -
SP11: - - - -
SP12:
SP13:
SP14:
SP15: - - - -
SP16:
SP17:

Relevant External Links for ANKRD10 Gene

GeneLoc Exon Structure for
ANKRD10
ECgene alternative splicing isoforms for
ANKRD10

Expression for ANKRD10 Gene

mRNA expression in normal human tissues for ANKRD10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ANKRD10 Gene

This gene is overexpressed in Bone (54.8) and CD8 Tcells (13.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ANKRD10 Gene



SOURCE GeneReport for Unigene cluster for ANKRD10 Gene Hs.525163

genes like me logo Genes that share expression patterns with ANKRD10: view

Protein tissue co-expression partners for ANKRD10 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD10 Gene

Orthologs for ANKRD10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD10 35
  • 99.6 (n)
  • 99.52 (a)
ANKRD10 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD10 36
  • 78 (a)
OneToOne
ANKRD10 35
  • 78.65 (n)
  • 72.47 (a)
dog
(Canis familiaris)
Mammalia ANKRD10 35
  • 84.52 (n)
  • 83.33 (a)
ANKRD10 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd10 16
Ankrd10 35
  • 83.29 (n)
  • 78.91 (a)
Ankrd10 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKRD10 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD10 36
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd10 35
  • 84.12 (n)
  • 81.39 (a)
chicken
(Gallus gallus)
Aves ANKRD10 35
  • 77.15 (n)
  • 72.28 (a)
ANKRD10 36
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD10 36
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd10 35
  • 66.67 (n)
  • 61.85 (a)
Str.12012 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11213 35
zebrafish
(Danio rerio)
Actinopterygii ankrd10a 36
  • 49 (a)
OneToMany
ankrd10b 36
  • 49 (a)
OneToMany
ankrd10b 35
  • 63.4 (n)
  • 56.29 (a)
zgc55353 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 50 (a)
OneToMany
Species with no ortholog for ANKRD10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD10 Gene

ENSEMBL:
Gene Tree for ANKRD10 (if available)
TreeFam:
Gene Tree for ANKRD10 (if available)

Paralogs for ANKRD10 Gene

Paralogs for ANKRD10 Gene

genes like me logo Genes that share paralogs with ANKRD10: view

Variants for ANKRD10 Gene

Sequence variations from dbSNP and Humsavar for ANKRD10 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs3742185 - 110,879,941(-) GTTTC(C/T)GAGTA nc-transcript-variant, reference, missense
rs6829 -- 110,878,917(-) TAGTG(A/G)AAATC nc-transcript-variant, utr-variant-3-prime
rs9838 -- 110,878,844(+) AAAAA(A/C)AAGGA nc-transcript-variant, utr-variant-3-prime
rs1137123 -- 110,899,961(-) GCGCC(A/C/G)GGATT intron-variant
rs1547178 -- 110,879,538(-) TGTAC(G/T)TTTTT nc-transcript-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ANKRD10 Gene

Variant ID Type Subtype PubMed ID
esv2504656 CNV Deletion 19546169
esv2018264 CNV Deletion 18987734
esv3077 CNV Deletion 18987735
esv6134 CNV Loss 19470904
esv2583876 CNV Deletion 19546169
esv1002915 CNV Deletion 20482838
esv1666847 CNV Deletion 17803354
esv2748046 CNV Deletion 23290073
esv29570 CNV Loss 19812545

Variation tolerance for ANKRD10 Gene

Residual Variation Intolerance Score: 21.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.58; 30.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD10 Gene

HapMap Linkage Disequilibrium report
ANKRD10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD10 Gene

Disorders for ANKRD10 Gene

Relevant External Links for ANKRD10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD10

No disorders were found for ANKRD10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD10 Gene

Publications for ANKRD10 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ANKRD10 Gene

Sources for ANKRD10 Gene

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