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ANKRD1 Gene

protein-coding   GIFtS: 62
GCID: GC10M092661

Ankyrin Repeat Domain 1 (Cardiac Muscle)

  See ANKRD1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat Domain 1 (Cardiac Muscle)1 2     CVARP2
Cardiac Ankyrin Repeat Protein2 3     MCARP2
Cytokine-Inducible Gene C-193 Protein2 3     Ankyrin Repeat Domain-Containing Protein 12
Cytokine-Inducible Nuclear Protein2 3     bA320F15.22
CARP2 3     Liver Ankyrin Repeat Domain 12
ALRP2     C1933
C-1932     HA1A23

External Ids:    HGNC: 158191   Entrez Gene: 270632   Ensembl: ENSG000001486777   OMIM: 6095995   UniProtKB: Q153273   

Export aliases for ANKRD1 gene to outside databases

Previous GC identifers: GC10M092336 GC10M086300


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANKRD1 Gene:
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and
TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor.
Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be
involved in the myofibrillar stretch-sensor system. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANKRD1 Gene:
ANKRD1 (ankyrin repeat domain 1 (cardiac muscle)) is a protein-coding gene. Diseases associated with ANKRD1 include congenital total pulmonary venous return anomaly, and diastolic heart failure. GO annotations related to this gene include p53 binding and transcription corepressor activity. An important paralog of this gene is ANKRD2.

UniProtKB/Swiss-Prot: ANKR1_HUMAN, Q15327
Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor
that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell
death in hepatoma cells

Gene Wiki entry for ANKRD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANKRD1 gene promoter:
         TBP   Lmo2   IRF-1   AP-2gamma   Evi-1   GATA-6   E2F   E2F-1   IRF-7A   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKRD1 promoter sequence
   Search Chromatin IP Primers for ANKRD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.31   Ensembl cytogenetic band:  10q23.31   HGNC cytogenetic band: 10q23.33

ANKRD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M092661:  view genomic region     (about GC identifiers)

Start:
92,671,853 bp from pter      End:
92,681,033 bp from pter
Size:
9,181 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ANKR1_HUMAN, Q15327 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 1  
Size: 319 amino acids; 36252 Da
Subunit: Interacts with YBX1 (By similarity). Interacts with TTN/titin
Secondary accessions: Q96LE7

Explore the universe of human proteins at neXtProt for ANKRD1: NX_Q15327

Explore proteomics data for ANKRD1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ANKRD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055206.2  
    ENSEMBL proteins: 
     ENSP00000360762  
    Reactome Protein details: Q15327

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    2 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q15327

    ProtoNet protein and cluster: Q15327

    1 Blocks protein domain: IPB002110 Ankyrin repeat signature

    UniProtKB/Swiss-Prot: ANKR1_HUMAN, Q15327
    Similarity: Contains 5 ANK repeats


    Find genes that share domains with ANKRD1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANKR1_HUMAN, Q15327
    Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor
    that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell
    death in hepatoma cells
    Induction: By TNF, IL1A/interleukin-1 alpha and parthenolide

         Gene Ontology (GO): Selected molecular function terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001085RNA polymerase II transcription factor binding IPI--
    GO:0001105RNA polymerase II transcription coactivator activity IDA--
    GO:0002039p53 binding IPI--
    GO:0003677DNA binding IDA7730328
    GO:0003714transcription corepressor activity TAS--
         
    Find genes that share ontologies with ANKRD1           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for ANKRD1:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Ankrd1):
     muscle  no phenotypic analysis 

    Find genes that share phenotypes with ANKRD1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for ANKRD1: Ankrd1tm1(KOMP)Vlcg Ankrd1tm1Krc

       genOway: Develop your customized and physiologically relevant rodent model for ANKRD1

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    miRTarBase miRNAs that target ANKRD1:
    hsa-mir-181a-5p (MIRT025157), hsa-mir-375 (MIRT019931)

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    1 qRT-PCR Assays for microRNA that regulate ANKRD1:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidANKRD1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ANKR1_HUMAN, Q15327: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12054667
    GO:0005654nucleoplasm TAS--
    GO:0005667transcription factor complex IEA--
    GO:0005737cytoplasm IDA12054667
    GO:0005829cytosol IDA19608030

    Find genes that share ontologies with ANKRD1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ANKRD1 About    
    See pathways by source

    SuperPathContained pathways About
    1Fatty acid, triacylglycerol, and ketone body metabolism
    Fatty acid, triacylglycerol, and ketone body metabolism0.65
    PPARA Activates Gene Expression0.63
    Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)0.65
    2Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    3Hypertrophy Model
    Hypertrophy Model


    Find genes that share SuperPaths with ANKRD1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ANKRD1
        Hypertrophy Model


    1 Reactome Pathway for ANKRD1
        PPARA activates gene expression


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKRD1
    Interactions:

        GeneGlobe Interaction Network for ANKRD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for ANKRD1 (Q153273 ENSP000003607624) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYPNQ86TC93, ENSP000003517904I2D: score=2 STRING: ENSP00000351790
    CASQ2O149583, ENSP000002614484I2D: score=1 STRING: ENSP00000261448
    TTNQ8WZ423I2D: score=1 
    CARM1ENSP000003256904STRING: ENSP00000325690
    CHD9ENSP000003815224STRING: ENSP00000381522
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 22):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter ----
    GO:0010976positive regulation of neuron projection development IEA--
    GO:0035690cellular response to drug IEA--
    GO:0035914skeletal muscle cell differentiation IEA--

    Find genes that share ontologies with ANKRD1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKRD1 (ANKR1)

    1 Novoseek inferred chemical compound relationship for ANKRD1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    doxorubicin 17.1 2 16828759 (1), 9278441 (1)



    Find genes that share compounds with ANKRD1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ANKRD1 gene: 
    NM_014391.2  

    Unigene Cluster for ANKRD1:

    Ankyrin repeat domain 1 (cardiac muscle)
    Hs.448589  [show with all ESTs]
    Unigene Representative Sequence: NM_014391
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000371697(uc001khe.1)
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    Additional mRNA sequence: 

    AK290960.1 AY903446.1 BC005191.1 BC018667.1 X83703.1 

    9 DOTS entries:

    DT.411150  DT.95315889  DT.100655665  DT.102825281  DT.121245750  DT.121245861  DT.91844161  DT.91891123 
    DT.95156598 

    Selected AceView cDNA sequences (see all 39):

    CB145719 NM_014391 BM717593 AA488072 BE924898 BM674869 BF229066 X83703 
    BE924910 BX500748 BG943776 BE924924 Z36249 BE924977 AJ706787 AL600131 
    BE925011 BF229054 BM999077 BE924985 C04160 BE924899 BQ291910 AA486364 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANKRD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAATTGAA
    ANKRD1 Expression
    About this image


    ANKRD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 14 entries
             Multinuclear Myocytes Lumbar Back Muscles
     
     Heart (Cardiovascular System)    fully expand to see all 6 entries
             Cardiac Fibroblasts Myocardium
             Heart Tube
             Cardiomyocyte-like progenitor cells
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Multinuclear Myocytes Forelimb Dorsal Muscles
     
     NULL (Uncategorized)    fully expand to see all 3 entries
             Endoderm progenitor-like cells
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
    ANKRD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANKRD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.448589

    UniProtKB/Swiss-Prot: ANKR1_HUMAN, Q15327
    Tissue specificity: Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in
    hepatoma cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ANKRD1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd11 , 5 ankyrin repeat domain 1 (cardiac muscle)1, 5 87.25(n)1
    90.28(a)1
      19 (30.52 cM)5
    1077651  NM_013468.31  NP_038496.21 
     361119655 
    chicken
    (Gallus gallus)
    Aves ANKRD11 ankyrin repeat domain 1 (cardiac muscle) 71.89(n)
    70.53(a)
      378926  NM_204405.1  NP_989736.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD16
    ankyrin repeat domain 1 (cardiac muscle)
    75(a)
    1 ↔ 1
    GL343219.1(702946-723192)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ankrd11 ankyrin repeat domain 1 (cardiac muscle) 70.65(n)
    67.3(a)
      594995  NM_001030436.1  NP_001025607.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570806362   -- 90.49(n)    57080636 


    ENSEMBL Gene Tree for ANKRD1 (if available)
    TreeFam Gene Tree for ANKRD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANKRD1 gene
    ANKRD22  GABPB12  ANKRD232  GABPB22  ANKRD62  
    6 SIMAP similar genes for ANKRD1 using alignment to 2 protein entries:     ANKR1_HUMAN (see all proteins):
    ANKRD23    ANKRD2    CDKN2D    PSMD10    DKFZp761E1322    MTPN

    Find genes that share paralogs with ANKRD1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANKRD1 (see all 311)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1423541331,2,,4
    CTotal anomalous pulmonary venous return (TAPVR)4 --93046395(+) GTTCCG/ATCTAA 2 /T /M mis11Minor allele frequency- A:0.00NA 4230
    rs1120741751,2
    C--92676188(+) TTACA-/TGTGTGT 1 -- int12Minor allele frequency- TG:0.00CSA 4
    rs111863621,2
    H--93039176(+) GGGGTC/GTCTTT 1 -- ds50014Minor allele frequency- G:0.00NS EA 420
    rs1381429041,2
    --93039222(+) CCTTTC/GTGTCT 1 -- ds50010--------
    rs1492318171,2
    --93039266(+) GTGGCA/GTTTCG 1 -- ds50010--------
    rs111863631,2
    C,H--93039344(+) gaaatC/Ttgcat 1 -- ds50015Minor allele frequency- T:0.00NS EA NA 422
    rs108818511,2
    C,A,H--93039417(+) CATTTC/TTAATC 1 -- ds50015Minor allele frequency- T:0.00NS EA NA 422
    rs108818521,2
    C,A--93039422(+) CTAATC/TTGCAA 1 -- ds50011Minor allele frequency- T:0.50NA 2
    rs1433680651,2
    --93039454(+) AAAAAA/CCCCTC 1 -- ds50010--------
    rs669854121,2
    C,F--93039462(+) CTCCTG/ATATAG 1 -- ds50012Minor allele frequency- A:0.50NA 4

    HapMap Linkage Disequilibrium report for ANKRD1 (92671853 - 92681033 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ANKRD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831945CNV Gain17160897

    Human Gene Mutation Database (HGMD): ANKRD1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKRD1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609599    OMIM disorders: --

    UniProtKB/Swiss-Prot: ANKR1_HUMAN, Q15327
  • Total anomalous pulmonary venous return (TAPVR) [MIM:106700]: Rare congenital heart disease (CHD) in
    which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into
    either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a
    prevalence of approximately 1 out of 15'000 live births. Note=The disease may be caused by mutations affecting
    the gene represented in this entry

  • 4 diseases for ANKRD1:    
    About MalaCards
    congenital total pulmonary venous return anomaly    diastolic heart failure    ankrd1-related dilated cardiomyopathy    scimitar syndrome

    1 disease from the University of Copenhagen DISEASES database for ANKRD1:
    Scimitar syndrome

    Find genes that share disorders with ANKRD1           About GenesLikeMe

    4 Novoseek inferred disease relationships for ANKRD1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cardiac hypertrophy 40.3 3 14499857 (1), 12004005 (1)
    heart failure 40.2 13 19359327 (4), 14499857 (1), 16828759 (1), 19525294 (1) (see all 5)
    hypertrophy 38.3 6 15136035 (2), 14499857 (1), 12384280 (1)
    muscular dystrophies 37.5 4 12746480 (1), 17239933 (1)

    Genetic Association Database (GAD): ANKRD1
    Human Genome Epidemiology (HuGE) Navigator: ANKRD1 (6 documents)

    Export disorders for ANKRD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANKRD1 gene, integrated from 10 sources (see all 60):
    (articles sorted by number of sources associating them with ANKRD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells. (PubMed id 7730328)1, 2, 3, 9 Chu W.... Presky D.H. (J. Biol. Chem. 1995)
    2. Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy. (PubMed id 19608031)1, 4, 9 Arimura T....Kimura A. (J. Am. Coll. Cardiol. 2009)
    3. ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene. (PubMed id 19608030)1, 4, 9 Moulik M....Towbin J.A. (J. Am. Coll. Cardiol. 2009)
    4. Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy. (PubMed id 19525294)1, 4, 9 Duboscq-Bidot L....Villard E. (Eur. Heart J. 2009)
    5. Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. (PubMed id 15805281)1, 2, 9 Park J.-H.... Kim D.-G. (Cancer Res. 2005)
    6. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (Pharmacogenomics 2010)
    7. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    8. Transcriptional deregulation and a missense mutation define ANKRD1 as a candidate gene for total anomalous pulmonary venous return. (PubMed id 18273862)1, 2 Cinquetti R.... Acquati F. (Hum. Mutat. 2008)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27063 HGNC: 15819 AceView: ANKRD1 Ensembl:ENSG00000148677 euGenes: HUgn27063
    ECgene: ANKRD1 H-InvDB: ANKRD1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANKRD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANKRD1 gene:
    Search GeneIP for patents involving ANKRD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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