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Aliases for ANKMY1 Gene

Aliases for ANKMY1 Gene

  • Ankyrin Repeat And MYND Domain Containing 1 2 3 5
  • Zinc Finger MYND Domain-Containing Protein 13 3 4
  • Testis-Specific Ankyrin-Like Protein 1 3 4
  • ZMYND13 3 4
  • TSAL1 4

External Ids for ANKMY1 Gene

Previous GeneCards Identifiers for ANKMY1 Gene

  • GC02M241438
  • GC02M241739
  • GC02M241138
  • GC02M233174

Summaries for ANKMY1 Gene

GeneCards Summary for ANKMY1 Gene

ANKMY1 (Ankyrin Repeat And MYND Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKMY1 Gene

Genomics for ANKMY1 Gene

Regulatory Elements for ANKMY1 Gene

Enhancers for ANKMY1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ANKMY1 on UCSC Golden Path with GeneCards custom track

Promoters for ANKMY1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKMY1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKMY1 Gene

Chromosome:
2
Start:
240,479,422 bp from pter
End:
240,569,209 bp from pter
Size:
89,788 bases
Orientation:
Minus strand

Genomic View for ANKMY1 Gene

Genes around ANKMY1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKMY1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKMY1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKMY1 Gene

Proteins for ANKMY1 Gene

  • Protein details for ANKMY1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2S6-ANKY1_HUMAN
    Recommended name:
    Ankyrin repeat and MYND domain-containing protein 1
    Protein Accession:
    Q9P2S6
    Secondary Accessions:
    • B2RB78
    • Q4ZFV3
    • Q8IYX5
    • Q8NDK5
    • Q9H0V8
    • Q9NX10

    Protein attributes for ANKMY1 Gene

    Size:
    941 amino acids
    Molecular mass:
    105516 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKMY1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKMY1 Gene

Proteomics data for ANKMY1 Gene at MOPED

Post-translational modifications for ANKMY1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKMY1 Gene

Domains & Families for ANKMY1 Gene

Protein Domains for ANKMY1 Gene

Suggested Antigen Peptide Sequences for ANKMY1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9P2S6

UniProtKB/Swiss-Prot:

ANKY1_HUMAN :
  • Contains 7 ANK repeats.
Similarity:
  • Contains 7 ANK repeats.
  • Contains 3 MORN repeats.
  • Contains 1 MYND-type zinc finger.
genes like me logo Genes that share domains with ANKMY1: view

Function for ANKMY1 Gene

genes like me logo Genes that share phenotypes with ANKMY1: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKMY1 Gene

Localization for ANKMY1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKMY1 Gene COMPARTMENTS Subcellular localization image for ANKMY1 gene
Compartment Confidence
cytosol 3
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKMY1 Gene

Pathways & Interactions for ANKMY1 Gene

SuperPathways for ANKMY1 Gene

No Data Available

Interacting Proteins for ANKMY1 Gene

Gene Ontology (GO) - Biological Process for ANKMY1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKMY1 Gene

Drugs & Compounds for ANKMY1 Gene

No Compound Related Data Available

Transcripts for ANKMY1 Gene

mRNA/cDNA for ANKMY1 Gene

(30) REFSEQ mRNAs :
(15) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(24) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKMY1 Gene

Ankyrin repeat and MYND domain containing 1:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKMY1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
SP1: - - - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: - -
SP6:

Relevant External Links for ANKMY1 Gene

GeneLoc Exon Structure for
ANKMY1
ECgene alternative splicing isoforms for
ANKMY1

Expression for ANKMY1 Gene

mRNA expression in normal human tissues for ANKMY1 Gene

mRNA differential expression in normal tissues according to GTEx for ANKMY1 Gene

This gene is overexpressed in Testis (x6.2).

Protein differential expression in normal tissues from HIPED for ANKMY1 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKMY1 Gene



SOURCE GeneReport for Unigene cluster for ANKMY1 Gene Hs.656615

genes like me logo Genes that share expression patterns with ANKMY1: view

Protein tissue co-expression partners for ANKMY1 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKMY1 Gene

Orthologs for ANKMY1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKMY1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ANKMY1 35
  • 77.62 (n)
  • 71.36 (a)
ANKMY1 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankmy1 35
  • 73.58 (n)
  • 68.13 (a)
Ankmy1 16
Ankmy1 36
  • 62 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ANKMY1 35
  • 97.88 (n)
  • 97.8 (a)
ANKMY1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankmy1 35
  • 71.96 (n)
  • 66.27 (a)
cow
(Bos Taurus)
Mammalia ANKMY1 36
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKMY1 36
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 48 (a)
OneToMany
-- 36
  • 65 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 26 (a)
OneToMany
chicken
(Gallus gallus)
Aves ANKMY1 35
  • 58.56 (n)
  • 53.32 (a)
ANKMY1 36
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKMY1 36
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankmy1 35
  • 56.46 (n)
  • 51.25 (a)
zebrafish
(Danio rerio)
Actinopterygii ankmy1 35
  • 49.5 (n)
  • 41.42 (a)
ankmy1 36
  • 35 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
OneToOne
Species with no ortholog for ANKMY1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKMY1 Gene

ENSEMBL:
Gene Tree for ANKMY1 (if available)
TreeFam:
Gene Tree for ANKMY1 (if available)

Paralogs for ANKMY1 Gene

genes like me logo Genes that share paralogs with ANKMY1: view

No data available for Paralogs for ANKMY1 Gene

Variants for ANKMY1 Gene

Sequence variations from dbSNP and Humsavar for ANKMY1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs35278753 - 240,529,458(+) GCCAT(C/G/T)GGGGT intron-variant, nc-transcript-variant, reference, missense
rs35996697 - 240,524,178(+) TGGTC(C/T)ATGGA intron-variant, nc-transcript-variant, reference, missense
rs3796118 - 240,524,098(+) ACACG(A/C/T)CCTCA intron-variant, nc-transcript-variant, reference, missense
rs3821348 - 240,524,036(+) ACACA(A/C/T)GTTGG intron-variant, nc-transcript-variant, reference, missense
rs35044862 - 240,511,934(+) TGTCC(A/G)TGCTG intron-variant, nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ANKMY1 Gene

Variant ID Type Subtype PubMed ID
nsv876116 CNV Loss 21882294
nsv876125 CNV Loss 21882294
nsv508899 CNV Insertion 20534489
nsv876127 CNV Loss 21882294
dgv1295e1 CNV Complex 17122850
nsv876132 CNV Loss 21882294
nsv876133 CNV Loss 21882294
essv1993 CNV CNV 17122850
nsv876136 CNV Loss 21882294
nsv834586 CNV Loss 17160897
nsv3239 CNV Insertion 18451855
nsv10226 CNV Gain 18304495
nsv515975 CNV Gain 19592680
esv2721934 CNV Deletion 23290073
dgv4471n71 CNV Loss 21882294
nsv876138 CNV Gain 21882294
nsv438384 CNV Loss 16468122
esv5720 OTHER Inversion 19470904
dgv4472n71 CNV Loss 21882294
nsv819352 CNV Loss 19587683
nsv876144 CNV Loss 21882294
esv1184193 CNV Insertion 17803354
dgv4473n71 CNV Loss 21882294
nsv876148 CNV Loss 21882294
dgv4474n71 CNV Loss 21882294
dgv4475n71 CNV Loss 21882294
nsv876157 CNV Loss 21882294
nsv821937 CNV Gain 20364138
nsv876160 CNV Loss 21882294

Variation tolerance for ANKMY1 Gene

Residual Variation Intolerance Score: 93.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.55; 72.11% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ANKMY1 Gene

Disorders for ANKMY1 Gene

Relevant External Links for ANKMY1

Genetic Association Database (GAD)
ANKMY1
Human Genome Epidemiology (HuGE) Navigator
ANKMY1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKMY1

No disorders were found for ANKMY1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKMY1 Gene

Publications for ANKMY1 Gene

  1. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 3 48 67
  2. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X. … Vidal M. (Cell 2016) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ANKMY1 Gene

Sources for ANKMY1 Gene

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