ANKLE2 Gene
protein-coding GIFtS: 46
GCID: GC12M133302
|
|
ankyrin repeat and LEM domain containing 2(Previous name: KIAA0692 )
(Previous symbol: KIAA0692)
| |
Aliases
for ANKLE2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat And LEM Domain Containing 21 2 | | LEM Domain-Containing Protein 42 3 | | KIAA06921 2 3 | | Ankyrin Repeat And LEM Domain-Containing Protein 22 | | LEMD71 2 | | LEM Domain Containing 72 | | Lem41 2 | | LEM43 |
Export aliases for ANKLE2 gene to outside databasesPrevious GC identifers: GC12M131812 GC12M130081 |
Summaries
for ANKLE2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ANKL2_HUMAN, Q86XL3Function: Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitoticexit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylationof BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whetherit acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex
|
Genomic Views
for ANKLE2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_024477.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKLE2 gene promoter:
HFH-3 NRSF form 1 MIF-1 Ik-3 NRSF form 2 NF-AT FOXL1 FOXI1 HFH-1 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKLE2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKLE2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.33 Ensembl cytogenetic band: 12q24.33 HGNC cytogenetic band: 12q24.33ANKLE2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M133302: view genomic region
(about GC identifiers)
Start:
|
133,302,254 bp from pter |
End:
|
133,338,474 bp from pter |
Size:
|
36,221 bases |
Orientation:
|
minus strand |
|
Proteins
for ANKLE2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANKL2_HUMAN, Q86XL3 (See
protein sequence)Recommended Name: Ankyrin repeat and LEM domain-containing protein 2 Size: 938 amino acids; 104114 Da
Subunit: Interacts with BAF/BANF1. Interacts with protein phosphatase 2A (PP2A) components PPP2C (PPP2CA or PPP2CB) andPPP2R1A
Subcellular location: Endoplasmic reticulum membrane; Single-pass type III membrane protein
Sequence caution: Sequence=BAG51259.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8KAG3 B3KN97 B3KSF8 O75176 Q6P6A5 Q8TAZ9 Q96DH4Alternative splicing: 3 isoforms: Q86XL3-1 Q86XL3-2 Q86XL3-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ANKLE2: NX_Q86XL3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86XL3
ANKLE2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055929.1
ENSEMBL proteins: ENSP00000446268 ENSP00000350686 ENSP00000437807 ENSP00000438551 ENSP00000445760 ENSP00000437585 ENSP00000438515 ENSP00000445718 ENSP00000337651 Reactome Protein details: Q86XL3
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ANKLE2 for ontologies About GeneDecksing
ANKLE2 Antibody Products:
Assay Products for ANKLE2: |
Protein
Domains /
Families
for ANKLE2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKLE2 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86XL3ProtoNet protein and cluster: Q86XL3 2 Blocks protein families: IPB002110 Ankyrin repeat signature IPB011015 LEM-like fold
UniProtKB/Swiss-Prot: ANKL2_HUMAN, Q86XL3Similarity: Belongs to the ANKLE2 familySimilarity: Contains 1 ANK repeatSimilarity: Contains 1 LEM domain |
Function
for ANKLE2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ANKL2_HUMAN, Q86XL3Function: Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitoticexit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylationof BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whetherit acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ANKLE2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKLE2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKLE2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0008601 | protein phosphatase type 2A regulator activity |
TAS | -- | | GO:0051721 | protein phosphatase 2A binding |
IDA | -- |
ANKLE2 for ontologies About GeneDecksing
|
Pathways & Interactions
for ANKLE2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | M Phase | | | 2 | Cell Cycle | | | 3 | Clearance of Nuclear Envelope Membranes from Chromatin | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/8 
Reactome Pathways for ANKLE2 (see all 8)
ANKLE2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKLE2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/9 Interacting proteins for ANKLE2 (Q86XL31, 3 ENSP000003506864) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007067 | mitosis |
IEA | -- | | GO:0007084 | mitotic nuclear envelope reassembly |
IMP | -- | | GO:0035307 | positive regulation of protein dephosphorylation |
IDA | -- | | GO:0042326 | negative regulation of phosphorylation |
IDA | -- | | GO:0050790 | regulation of catalytic activity |
TAS | -- |
ANKLE2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ANKLE2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKLE2
Search CenterWatch for drugs/clinical trials and news about ANKLE2 / ANKL2
|
Transcripts
for ANKLE2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKLE2 gene: NM_015114.1 Unigene Cluster for ANKLE2: Ankyrin repeat and LEM domain containing 2 Hs.654628 [show with all ESTs]Unigene Representative Sequence: NM_01511414 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000539605 ENST00000357997(uc009zyw.1 uc001ukx.2) ENST00000542282
ENST00000542657 ENST00000542374 ENST00000538766 ENST00000505031 ENST00000439231
ENST00000538591 ENST00000535036 ENST00000545623 ENST00000538637 ENST00000546061
ENST00000337516(uc001uky.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ANKLE2 (NM_015114) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKLE2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKLE2 |
Additional cDNA sequence: AB014592.1 AK024061.1 AK025933.1 AK293028.1 BC001530.2 BC025347.1 BC043157.1 BC062373.1 BC082962.1 18 DOTS entries: DT.316056 DT.95224250 DT.95224259 DT.100731280 DT.121185683 DT.121185757 DT.100788149 DT.100788153 DT.91756153 DT.95114491 DT.102833243 DT.121185719 DT.40273805 DT.100788154 DT.121185640 DT.121185751 DT.92414992 DT.95224278
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for ANKLE2 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | - | | - | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | |
| ExUns: | 15b | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | · | 20c |
|---|
|
| SP1: | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | |
| SP5: | - | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ANKLE2
|
Expression
for ANKLE2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKLE2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTATTCTAAA
About this image
See ANKLE2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKLE2
SOURCE GeneReport for Unigene cluster: Hs.654628
SABiosciences Custom PCR Arrays for ANKLE2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKLE2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ANKLE2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKLE2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKLE2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKLE2 |
Orthologs
for ANKLE2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ANKLE2 gene from 6/18 species (see all 18) About this table
ENSEMBL Gene Tree for ANKLE2 (if available)
TreeFam Gene Tree for ANKLE2 (if available) |
Paralogs
for ANKLE2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ANKLE2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANKLE2 (133302254 - 133338474 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for ANKLE2
3 CNVs: 86687 76235 66382
1 Indel: 101662 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKLE2 |
|
Disorders
/ Diseases
for ANKLE2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANKLE2 for disorders About GeneDecksing
9  diseases for ANKLE2: About MalaCardspigmented villonodular synovitis complex regional pain syndrome villonodular synovitis scurvy
paine syndrome septic arthritis smallpox synovitis
arthritis
2 diseases from the University of Copenhagen DISEASES database for ANKLE2:Scurvy Pigmented villonodular synovitis Export disorders for ANKLE2 gene to outside databases
|
Publications
for ANKLE2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKLE2 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with ANKLE2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
- Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis. (PubMed id 22770216)1, 2 Asencio C.... Gorjanacz M. (2012)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome-wide association study of antibody response to smallpox vaccine. (PubMed id 22542470)1 Ovsyannikova I.G....Poland G.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
|
External Searches for ANKLE2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ANKLE2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKLE2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ANKLE2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKLE2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANKLE2 gene:
Search GeneIP for patents involving ANKLE2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKLE2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANKLE2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKLE2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANKLE2 | | OriGene 3'-UTR Clone for ANKLE2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKLE2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANKLE2 | | OriGene Custom Protein Services for ANKLE2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKLE2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKLE2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKLE2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKLE2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKLE2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKLE2 |
| |
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 |
 |
 | | | ANKLE2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKLE2 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKLE2 |
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