Aliases for ANKK1 Gene
Aliases for ANKK1 Gene
External Ids for ANKK1 Gene
- HGNC: 21027
- Entrez Gene: 255239
- Ensembl: ENSG00000170209
- OMIM: 608774
- UniProtKB: Q8NFD2
Previous GeneCards Identifiers for ANKK1 Gene
- GC11P113292
- GC11P112796
- GC11P112763
- GC11P109186
- GC11P113258
Summaries for ANKK1 Gene
-
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
GeneCards Summary for ANKK1 Gene
ANKK1 (Ankyrin Repeat And Kinase Domain Containing 1) is a Protein Coding gene. Diseases associated with ANKK1 include Impulse Control Disorder and Alexithymia. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is RIPK4.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKK1 Gene
Genomics for ANKK1 Gene
Regulatory Elements for ANKK1 Gene
Enhancers for ANKK1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH11G113312 | 1 | ENCODE | 10.5 | -71.6 | -71616 | 3.6 | HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 FOS SP3 | TTC12 DRD2 ENSG00000256757 ANKK1 LOC105369499 GC11M113268 |
| GH11G113265 | 0.6 | dbSUPER | 4.4 | -118.9 | -118938 | 7.3 | CTCF POLR2A SMARCA4 RAD21 EZH2 SPI1 | TTC12 LOC105369499 ANKK1 NCAM1-AS1 GC11P112980 |
| GH11G113263 | 0.5 | dbSUPER | 4.4 | -119.4 | -119425 | 6.6 | POLR2A SMARCA4 RAD21 EZH2 SPI1 | LOC105369499 TTC12 ANKK1 NCAM1-AS1 GC11P112980 |
| GH11G113278 | 0.4 | dbSUPER | 5.2 | -106.9 | -106872 | 1.3 | CTCF RAD21 | TTC12 ANKK1 NCAM1-AS1 GC11M113273 GC11M113271 GC11M113270 |
| GH11G113279 | 0.4 | dbSUPER | 5.2 | -106.6 | -106606 | 1.7 | CTCF RAD21 | TTC12 ANKK1 GC11M113270 GC11M113271 GC11M113273 NCAM1-AS1 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ANKK1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ANKK1 gene promoter:
Regulatory Element Products
Genomic Location for ANKK1 Gene
- Chromosome:
- 11
- Start:
- 113,386,038 bp from pter
- End:
- 113,400,418 bp from pter
- Size:
- 14,381 bases
- Orientation:
- Plus strand
Genomic View for ANKK1 Gene
Genes around ANKK1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.2 by Ensembl
- 11q23.2 by Entrez Gene
- 11q23.2 by HGNC
ANKK1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANKK1 Gene
Proteins for ANKK1 Gene
-
Protein details for ANKK1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NFD2-ANKK1_HUMAN
- Recommended name:
- Ankyrin repeat and protein kinase domain-containing protein 1
- Protein Accession:
- Q8NFD2
Protein attributes for ANKK1 Gene
- Size:
- 765 amino acids
- Molecular mass:
- 84632 Da
- Quaternary structure:
- No Data Available
Protein Expression for ANKK1 Gene
Selected DME Specific Peptides for ANKK1 Gene
- Q8NFD2:
-
- KPGNILL
- LHLDLKP
Post-translational modifications for ANKK1 Gene
Other Protein References for ANKK1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ANKK1
- Invitrogen Antibodies for ANKK1
- antibodies-online Antibodies for ANKK1: See all 36
- GeneTex ANKK1 antibody for ANKK1
Protein Products
-
OriGene Purified Proteins for ANKK1
- Search Origene for MassSpec and Protein Over-expression Lysates for ANKK1
- Origene Custom Protein Services for ANKK1
- Search GeneTex for Proteins for ANKK1
Assay Products
Domains & Families for ANKK1 Gene
Gene Families for ANKK1 Gene
Protein Domains for ANKK1 Gene
Suggested Antigen Peptide Sequences for ANKK1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NFD2UniProtKB/Swiss-Prot:
ANKK1_HUMAN :- Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
- Family:
-
- Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Function for ANKK1 Gene
Molecular function for ANKK1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + a protein = ADP + a phosphoprotein.
Enzyme Numbers (IUBMB) for ANKK1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0004674 | protein serine/threonine kinase activity | IEA | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016301 | kinase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for ANKK1 Gene
- GenomeRNAi human phenotypes for ANKK1:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased ionizing radiation sensitivity
- Decreased viability ratio
- Decreased viability
- Decreased vesicular stomatitis virus (VSV) infection
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased influenza A/WSN/33 replication
- Weakly decreased NFAT1-GFP nuclear translocation
- Increased cell viability after pRB stimulation
- Decreased substrate adherent cell growth
- Decreased cell proliferation
Animal Model Products
-
Taconic Biosciences Mouse Models for ANKK1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANKK1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKK1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKK1 gene
- Search ViGene Biosciences for ANKK1
CRISPR Products
-
OriGene CRISPR knockouts for ANKK1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKK1
- GenScript: Design CRISPR guide RNA sequences for ANKK1
miRNA Products
- Search ViGene Biosciences for ANKK1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ANKK1
- Browse OriGene Inhibitory RNA Products For ANKK1
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKK1 gene
Clone Products
-
OriGene ORF clones in human for ANKK1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ANKK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKK1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ANKK1
-
ViGene Biosciences adenoviral particle packaged cDNA for ANKK1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKK1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKK1 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKK1 Gene
Localization for ANKK1 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| nucleus | 2 |
| cytoskeleton | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKK1 Gene
Pathways & Interactions for ANKK1 Gene
No Data Available
Interacting Proteins for ANKK1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IEA | -- |
| GO:0016310 | phosphorylation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ANKK1 Gene
Drugs & Compounds for ANKK1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Aripiprazole | Approved, Investigational | Pharma | Antagonist | Antipsychotic, High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist | 358 | |
| Bupropion | Approved | Pharma | 329 | |||
| Clozapine | Approved | Pharma | Antagonist | Antipsychotic medication | 117 | |
| Disulfiram | Approved | Pharma | Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities | 37 | ||
| Ethanol | Approved | Pharma | 2137 |
Transcripts for ANKK1 Gene
mRNA/cDNA for ANKK1 Gene
- (5) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (3) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ANKK1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ANKK1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKK1
- GenScript: Design CRISPR guide RNA sequences for ANKK1
miRNA Products
- Search ViGene Biosciences for ANKK1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ANKK1
- Browse OriGene Inhibitory RNA Products For ANKK1
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKK1 gene
Clone Products
-
OriGene ORF clones in human for ANKK1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ANKK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKK1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||
| SP2: |
Expression for ANKK1 Gene
mRNA differential expression in normal tissues according to GTEx for ANKK1 Gene
This gene is overexpressed in Pituitary (x5.5) and Skin - Sun Exposed (Lower leg) (x4.0).
This gene is overexpressed in Lung (56.5) and Heart (12.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKK1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ANKK1 Gene:
ANKK1SOURCE GeneReport for Unigene cluster for ANKK1 Gene:
Hs.448473mRNA Expression by UniProt/SwissProt for ANKK1 Gene:
Q8NFD2-ANKK1_HUMAN
Tissue specificity:
Highly expressed in brain and weakly expressed in placenta and spinal cord.
Evidence on tissue expression from TISSUES for ANKK1 Gene
- Nervous system(2.2)
Primer Products
-
OriGene qPCR primer pairs for ANKK1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKK1 Gene
Orthologs for ANKK1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ANKK1 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ANKK1 35 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ankk1 16 35 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ankk1 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ANKK1 35 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ANKK1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ANKK1 35 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ankk1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ankk1 35 34 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AVO2 37 |
|
|
|
| thale cress (Arabidopsis thaliana) |
eudicotyledons | KEG 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany |
- Species where no ortholog for ANKK1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ANKK1 Gene
(13) SIMAP similar genes for ANKK1 Gene using alignment to 3 proteins:
Variants for ANKK1 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_040362 | A breast infiltrating ductal carcinoma sample | ||||
| VAR_040372 | A lung large cell carcinoma sample | ||||
| VAR_040373 | A lung squamous cell carcinoma sample | ||||
| VAR_040374 | A lung neuroendocrine carcinoma sample | ||||
| rs1800497 | Pathogenic | 113,400,106(-) | TGCCT(C/T)GACCA | reference, missense |
Residual Variation Intolerance Score:
99.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.49;
88.76% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ANKK1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKK1 Gene
Disorders for ANKK1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| impulse control disorder |
|
|
| alexithymia |
|
|
| antisocial personality disorder |
|
|
| heroin dependence |
|
|
| keratinizing squamous cell carcinoma |
|
|
Search ANKK1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ANKK1
No data available for UniProtKB/Swiss-Prot and Genatlas for ANKK1 Gene
Publications for ANKK1 Gene
- Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. (PMID: 15146457) Neville M.J. … Walton R.T. (Hum. Mutat. 2004) 2 3 4 22 64
- Genetic diagnostics of functional variants of the human dopamine D2 receptor gene. (PMID: 19512960) Doehring A. … LAPtsch J. (Psychiatr. Genet. 2009) 3 22 46 64
- Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study. (PMID: 18698520) McAllister T.W. … Tsongalis G.J. (Brain Inj 2008) 3 22 46 64
- Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. (PMID: 17850642) Dick D.M. … Goate A. (Alcohol. Clin. Exp. Res. 2007) 3 22 46 64
- The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia. (PMID: 14741327) Dubertret C. … Gorwood P. (Schizophr. Res. 2004) 3 4 22 64
Products for ANKK1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ANKK1
- Search Origene for MassSpec and Protein Over-expression Lysates for ANKK1
- Origene Custom Protein Services for ANKK1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ANKK1
- Browse OriGene Inhibitory RNA Products For ANKK1
- OriGene qPCR primer pairs for ANKK1
- OriGene CRISPR knockouts for ANKK1
- OriGene ORF clones in human for ANKK1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ANKK1
- GenScript: Next-day shipping cDNA ORF clone for ANKK1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ANKK1
- GenScript Custom Assay Services for ANKK1
- GenScript Custom overexpressing Cell Line Services for ANKK1
- GenScript: Design CRISPR guide RNA sequences for ANKK1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ANKK1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ANKK1
- Novus Biologicals proteins and lysates for ANKK1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for ANKK1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- ViGene Biosciences adenoviral particle packaged cDNA for ANKK1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ANKK1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ANKK1 gene
- Search ViGene Biosciences for ANKK1
- Horizon Cell Lines for ANKK1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANKK1
- VectorBuilder custom plasmid, inducible vectors for ANKK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKK1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ANKK1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer