ANKHD1 Gene
protein-coding GIFtS: 47
GCID: GC05P139763
|
|
ankyrin repeat and KH domain containing 1
| |
Aliases
for ANKHD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat And KH Domain Containing 11 2 | | FLJ141271 | | MASK1 2 3 5 | | FLJ202881 | | KIAA10851 3 5 | | Ankyrin Repeat And KH Domain-Containing Protein 12 | | VBARP2 3 5 | | Multiple Ankyrin Repeats, Single KH-Domain Homolog2 | | HIV-1 Vpr-Binding Ankyrin Repeat Protein2 3 | | HMASK1 | | FLJ100421 | | Multiple Ankyrin Repeats Single KH Domain3 | | FLJ119791 | | |
Export aliases for ANKHD1 gene to outside databasesPrevious GC identifer: GC05P139811 |
Summaries
for ANKHD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ANKHD1:
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought tofunction as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play anantiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of whichgenerates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in aprotein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to analternate reading frame for the EIF4EBP3 segments. (provided by RefSeq, Sep 2010)
UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3Function: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemiacells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through itsregulation of caspases
Gene Wiki entry for ANKHD1
|
Genomic Views
for ANKHD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_029289.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKHD1 gene promoter:
PPAR-gamma1 PPAR-gamma2 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKHD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKHD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.3 Ensembl cytogenetic band: 5q31.3 HGNC cytogenetic band: 5q31.3ANKHD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P139763: view genomic region
(about GC identifiers)
Start:
|
139,781,399 bp from pter |
End:
|
139,929,163 bp from pter |
Size:
|
147,765 bases |
Orientation:
|
plus strand |
|
Proteins
for ANKHD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3 (See
protein sequence)Recommended Name: Ankyrin repeat and KH domain-containing protein 1 Size: 2542 amino acids; 269458 Da
Subunit: Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAA91417.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB13958.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NH85 Q149P2 Q8IWZ2 Q8WY90 Q96G77 Q96GK0 Q9H2U0 Q9HA95 Q9NWG4 Q9UPR7Alternative splicing: 6 isoforms: Q8IWZ3-1 Q8IWZ3-2 Q8IWZ3-3 Q8IWZ3-4 Q8IWZ3-5 Q8IWZ3-6 Explore the universe of human proteins at neXtProt for ANKHD1: NX_Q8IWZ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IWZ3
ANKHD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001183959.1 NP_060217.1 NP_060448.1 NP_078944.2
ENSEMBL proteins: ENSP00000354085 ENSP00000394489 ENSP00000378212 ENSP00000421069 ENSP00000378211 ENSP00000246149 ENSP00000405602 ENSP00000393204 ENSP00000390034 ENSP00000410959 ENSP00000415887 ENSP00000405345 ENSP00000297183 ENSP00000437687
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ANKHD1 for ontologies About GeneDecksing
ANKHD1 Antibody Products:
Assay Products for ANKHD1: |
Protein
Domains /
Families
for ANKHD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKHD1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IWZ3ProtoNet protein and cluster: Q8IWZ3 UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3Similarity: Belongs to the mask familySimilarity: Contains 25 ANK repeatsSimilarity: Contains 1 KH domain |
Function
for ANKHD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3Function: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemiacells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through itsregulation of caspases
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): ANKHD1 (NM_017747) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKHD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKHD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKHD1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ANKHD1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ANKHD1:
|
Pathways & Interactions
for ANKHD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKHD1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/22 Interacting proteins for ANKHD1 (Q8IWZ31, 3 ENSP000002971834) via UniProtKB, MINT, STRING, and/or I2D (see all 22)About this table
|
Drugs & Compounds
for ANKHD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKHD1
Search CenterWatch for drugs/clinical trials and news about ANKHD1 / ANKH1
|
Transcripts
for ANKHD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKHD1 gene (4 alternative transcripts): NM_001197030.1 NM_017747.2 NM_017978.2 NM_024668.3 Unigene Cluster for ANKHD1: Ankyrin repeat and KH domain containing 1 Hs.594084 [show with all ESTs]Unigene Representative Sequence: NM_02069018/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000360839(uc003lfr.3 uc003lfu.1 uc003lfw.3 uc010jfl.3)
ENST00000421134(uc003lfq.2 uc003lft.1 uc003lfv.1) ENST00000394723(uc003lfo.3 uc003lfp.3 uc010jfk.3)
ENST00000511151 ENST00000394722 ENST00000490185 ENST00000246149 ENST00000412116
ENST00000465435 ENST00000506755 ENST00000462121 ENST00000506930 ENST00000431508
ENST00000433049 ENST00000435794 ENST00000432301 ENST00000475148 ENST00000495578
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ANKHD1 (NM_017747) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKHD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKHD1 |
Additional cDNA sequence: AF038869.1 AF217646.1 AF258557.1 AF521882.1 AK000295.1 AK000904.1 AK022041.1 AK024056.1 AK024189.1 AK074173.1 AK098574.1 AK310086.1 AL136943.1 AY070436.1 BC004457.1 BC009420.1 BC009909.2 BC010881.1 BC040231.1 BC069293.1 BC073751.1 BC117677.2 BC117678.2 BC127127.1 BC150486.2 24/53 DOTS entries (see all 53): DT.315554 DT.120809132 DT.92072044 DT.100041911 DT.92072041 DT.100694071 DT.100041909 DT.120809221 DT.442769 DT.100041915 DT.100041910 DT.100861359 DT.120809069 DT.120809262 DT.95166972 DT.100881049 DT.120809096 DT.423362 DT.95142762 DT.101984849 DT.451668 DT.75100112 DT.92072067 DT.95166709 24/365 AceView cDNA sequences (see all 365): AA478608 CB158942 AA968829 BQ189300 AI827947 AF217646 CK299454 AA731151 AA468583 AI658864 CB163696 AA243347 BQ015180 AF258557 BM828329 AU143608 BU955988 AI224516 CA438127 AI418259 BC073751 CD677537 AL045501 AI433670
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ANKHD1 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | · | 18c | · | 18d | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ANKHD1
|
Expression
for ANKHD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKHD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCACTGCTGC
About this image
See ANKHD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKHD1
SOURCE GeneReport for Unigene cluster: Hs.594084
UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3Tissue specificity: Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells withincreased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscleand brain
SABiosciences Custom PCR Arrays for ANKHD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKHD1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ANKHD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKHD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKHD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKHD1 |
Orthologs
for ANKHD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ANKHD1 gene from 8/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ANKHD11 |
ankyrin repeat and KH domain containing 1 |
82.09(n)
88.03(a) |
|
416143 NM_001204097.1 NP_001191026.1 |
lizard
(Anolis carolinensis) |
Reptilia |
---- |
-- |
86(a)20(a) |
1 ↔ manypossible ortholog |
4(77930894-78042767) 4(101979115-101980806) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.126102 |
Xenopus laevis transcribed sequence with weak similarity more |
80.89(n) |
|
48059061 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.76472 |
Danio rerio cDNA clone IMAGE2600225, partial cds |
76.99(n) |
|
BC059206.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
mask1 |
multiple ankyrin repeats single KH domain |
49.26(n)
48.83(a) |
|
50070 NM_176556.2 NP_788733.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
tag-1446R11A8.76 |
Temporarily Assigned Gene name family member (tag-...Ankyrin repeat and KH domain-containing protein R1... |
5(a)14(a) |
possible ortholog1 ↔ many |
IV(11038634-11047401) IV(10374884-10387275) |
rice
(Oryza sativa) |
Liliopsida |
-- |
ankyrin repeat domain-containing protein 50, putat... |
23(a) |
possible ortholog |
3(25568429-25570099) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
yahD6 |
ankyrin repeat protein |
21(a) |
possible ortholog |
Chromosome(334504-335109) |
ENSEMBL Gene Tree for ANKHD1 (if available)
TreeFam Gene Tree for ANKHD1 (if available) |
Paralogs
for ANKHD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANKHD1 gene
- TANC22 TNKS22 ANKRD172 ANK32 ANK12 ANKRD522 ANKHD1-EIF4EBP32 TNKS2
- ANKRD502 TANC12 INVS2 ANKRD282 ANK22 ANKRD442
18 SIMAP similar genes for ANKHD1 using alignment to 12 protein entries: ANKH1_HUMAN (see all proteins):DKFZp586G1024 ANKHD1-EIF4EBP3 FLJ00246 ANKRD17 NOVA1 ANK2
RAI14 IkBa ANKDD1A FANK1 GABPB1 PSMD10
DKFZp434B2328 ANKRD29 ANKRD7 DKFZp761E1322 MTPN ANKRD54
ANKHD1 for paralogs About GeneDecksing
|
Genomic Variants
for ANKHD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANKHD1 (139781399 - 139929163 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ANKHD1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKHD1 |
|
Disorders
/ Diseases
for ANKHD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANKHD1 for disorders About GeneDecksing
OMIM gene information: 610500
OMIM disorders: --
6  diseases for ANKHD1: About MalaCardstracheal stenosis hemosiderosis respiratory failure acute leukemia
ataxia leukemia
Export disorders for ANKHD1 gene to outside databases
|
Publications
for ANKHD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKHD1 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with ANKHD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis. (PubMed id 16098192)1, 2, 3 Miles M.C....Ayyavoo V. (2005)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2, 3 Kikuno R....Ohara O. (1999)
- Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. (PubMed id 14557257)1, 2, 9 Poulin F.... Sonenberg N. (2003)
- ANKHD1, ankyrin repeat and KH domain containing 1, is overexpressed in acute leukemias and is associated with SHP2 in K562 cells. (PubMed id 16956752)1, 2 Traina F.... Saad S.T.O. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 3 Wiemann S.... Poustka A. (2001)
- ANKHD1 regulates cell cycle progression and proliferat ion in multiple myeloma cells. (PubMed id 23142581)1 Dhyani A....Olalla Saad S.T. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
|
External Searches for ANKHD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ANKHD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKHD1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ANKHD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKHD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANKHD1 gene:
Search GeneIP for patents involving ANKHD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ANKHD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ANKHD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANKHD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKHD1 | | | OriGene Protein Over-expression Lysate for ANKHD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANKHD1 | | OriGene 3'-UTR Clone for ANKHD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKHD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANKHD1 | | OriGene Custom Protein Services for ANKHD1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKHD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKHD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKHD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKHD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKHD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKHD1 |
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| | | | Search Tocris compounds for ANKHD1 |
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 | | | ANKHD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKHD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for ANKHD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKHD1 |
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