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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKHD1 Gene

protein-coding   GIFtS: 50
GCID: GC05P139763

Ankyrin Repeat And KH Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat And KH Domain Containing 11 2     Ankyrin Repeat And KH Domain-Containing Protein 12
MASK2 3 5     Multiple Ankyrin Repeats, Single KH-Domain Homolog2
VBARP2 3 5     hMASK3
HIV-1 Vpr-Binding Ankyrin Repeat Protein2 3     Multiple Ankyrin Repeats Single KH Domain3
KIAA10853 5     

External Ids:    HGNC: 247141   Entrez Gene: 548822   Ensembl: ENSG000001315037   OMIM: 6105005   UniProtKB: Q8IWZ33   

Export aliases for ANKHD1 gene to outside databases

Previous GC identifer: GC05P139811


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANKHD1 Gene:
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to
function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an
antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which
generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting
in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to
an alternate reading frame for the EIF4EBP3 segments. (provided by RefSeq, Sep 2010)

GeneCards Summary for ANKHD1 Gene: 
ANKHD1 (ankyrin repeat and KH domain containing 1) is a protein-coding gene. Diseases associated with ANKHD1 include hemosiderosis, and tracheal stenosis. GO annotations related to this gene include protein binding and RNA binding. An important paralog of this gene is TANC2.

UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3
Function: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia
cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its
regulation of caspases

Gene Wiki entry for ANKHD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_029289.11  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANKHD1 gene promoter:
         PPAR-gamma1   PPAR-gamma2   C/EBPalpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ANKHD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKHD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

ANKHD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKHD1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P139763:  view genomic region     (about GC identifiers)

Start:
139,781,399 bp from pter      End:
139,929,163 bp from pter
Size:
147,765 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3 (See protein sequence)
Recommended Name: Ankyrin repeat and KH domain-containing protein 1  
Size: 2542 amino acids; 269458 Da
Subunit: Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAA91417.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB13958.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NH85 Q149P2 Q8IWZ2 Q8WY90 Q96G77 Q96GK0 Q9H2U0 Q9HA95 Q9NWG4 Q9UPR7
Alternative splicing: 6 isoforms:  Q8IWZ3-1   Q8IWZ3-2   Q8IWZ3-3   Q8IWZ3-4   Q8IWZ3-5   Q8IWZ3-6   

Explore the universe of human proteins at neXtProt for ANKHD1: NX_Q8IWZ3

Explore proteomics data for ANKHD1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IWZ3

  • ANKHD1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANKHD1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001183959.1  NP_060217.1  NP_060448.1  NP_078944.2  

    ENSEMBL proteins: 
     ENSP00000354085   ENSP00000394489   ENSP00000378212   ENSP00000421069   ENSP00000378211  
     ENSP00000246149   ENSP00000405602   ENSP00000393204   ENSP00000390034   ENSP00000410959  
     ENSP00000415887   ENSP00000405345   ENSP00000297183   ENSP00000437687  

    Human Recombinant Protein Products for ANKHD1: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ANKHD1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    ANKHD1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    4 InterPro protein domains:
     IPR004087 KH_dom
     IPR004088 KH_dom_type_1
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q8IWZ3

    ProtoNet protein and cluster: Q8IWZ3

    UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3
    Similarity: Belongs to the mask family
    Similarity: Contains 25 ANK repeats
    Similarity: Contains 1 KH domain


    ANKHD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANKH1_HUMAN, Q8IWZ3
    Function: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia
    cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its
    regulation of caspases

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI12812986
         
    ANKHD1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ANKHD1:
     Cell cycle / mitosis defect  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKHD1 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKHD1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKHD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/21 Interacting proteins for ANKHD1 (Q8IWZ31, 3 ENSP000002971834) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542533, ENSP000002447694I2D: score=2 STRING: ENSP00000244769
    UNC93B1Q9H1C43, ENSP000002274714I2D: score=1 STRING: ENSP00000227471
    YWHAEP622583, ENSP000002643354I2D: score=1 STRING: ENSP00000264335
    YWHAGP619813, ENSP000003063304I2D: score=1 STRING: ENSP00000306330
    LMLNQ96KR43I2D: score=5 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANKHD1 (ANKH1)

    Search CenterWatch for drugs/clinical trials and news about ANKHD1 / ANKH1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANKHD1 gene (4 alternative transcripts): 
    NM_001197030.1  NM_017747.2  NM_017978.2  NM_024668.3  

    Unigene Cluster for ANKHD1:

    Ankyrin repeat and KH domain containing 1
    Hs.594084  [show with all ESTs]
    Unigene Representative Sequence: NM_020690
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000360839(uc003lfr.3 uc003lfu.1 uc003lfw.3 uc010jfl.3)
    ENST00000421134(uc003lfq.2 uc003lft.1 uc003lfv.1) ENST00000394723(uc003lfo.3 uc003lfp.3 uc010jfk.3)
    ENST00000511151 ENST00000394722 ENST00000490185 ENST00000246149 ENST00000412116
    ENST00000465435 ENST00000506755 ENST00000462121 ENST00000506930 ENST00000431508
    ENST00000433049 ENST00000435794 ENST00000432301 ENST00000475148 ENST00000495578

    miRNA
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    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate ANKHD1 (see all 26):
    hsa-miR-411* hsa-miR-30c hsa-miR-379* hsa-miR-605 hsa-miR-30d hsa-miR-221 hsa-miR-374c hsa-miR-30a
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    Additional mRNA sequence: 

    AF038869.1 AF217646.1 AF258557.1 AF521882.1 AK000295.1 AK000904.1 AK022041.1 AK024056.1 
    AK024189.1 AK074173.1 AK098574.1 AK310086.1 AL136943.1 AY070436.1 BC004457.1 BC009420.1 
    BC009909.2 BC010881.1 BC040231.1 BC069293.1 BC073751.1 BC117677.2 BC117678.2 BC127127.1 
    BC150486.2 

    24/53 DOTS entries (see all 53):

    DT.315554  DT.120809132  DT.92072044  DT.100041911  DT.92072041  DT.100694071  DT.100041909  DT.120809221 
    DT.442769  DT.100041915  DT.100041910  DT.100861359  DT.120809069  DT.120809262  DT.95166972  DT.100881049 
    DT.120809096  DT.423362  DT.95142762  DT.101984849  DT.451668  DT.75100112  DT.92072067  DT.95166709 

    24/365 AceView cDNA sequences (see all 365):

    AW440943 BC040231 BP345777 AI439257 BQ433415 BE172980 BX459123 BE218912 
    CB163900 AU117271 NM_003732 AI433670 BU170010 CF272490 AI613096 AK125734 
    AA045565 BC004457 AW026034 BM709417 AA653147 BU944670 CB162217 NM_017747 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ANKHD1 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d ^ 16 ^ 17a · 17b · 17c ^
    SP1:                                                                                                                                      -     -     -         
    SP2:                                                                                                                                            -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                            -     -         
    SP5:                                                                                                                                                            

    ExUns: 18a · 18b · 18c · 18d ^ 19 ^ 20 ^ 21 ^ 22 ^ 23
    SP1:                                                      
    SP2:                    -           -                     
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for ANKHD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKHD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCACTGCTGC
    ANKHD1 Expression
    About this image


    See ANKHD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANKHD1

    SOURCE GeneReport for Unigene cluster: Hs.594084

    UniProtKB/Swiss-Prot: ANKH1_HUMAN, Q8IWZ3
    Tissue specificity: Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells
    with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in
    muscle and brain

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKHD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ANKHD1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankhd15 ankyrin repeat and KH domain containing 1   --   18 (19.46 cM) 36559987 
    chicken
    (Gallus gallus)
    Aves ANKHD11 ankyrin repeat and KH domain containing 1 82.09(n)
    88.03(a)
      416143  NM_001204097.1  NP_001191026.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    82(a)
    28(a)
    1 ↔ many
    possible ortholog
    4(77930894-78028396)
    4(101979220-101980806)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.126102 Xenopus laevis transcribed sequence with weak similarity more 80.89(n)    48059061 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.76472 Danio rerio cDNA clone IMAGE2600225, partial cds 76.99(n)    BC059206.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mask1 multiple ankyrin repeats single KH domain 49.26(n)
    48.83(a)
      50070  NM_176556.2  NP_788733.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R11A8.76
    nphp-26
    Protein NPHP-2
    25(a)
    15(a)
    1 ↔ many
    possible ortholog
    IV(10374905-10387296)
    V(1895797-1906560)


    ENSEMBL Gene Tree for ANKHD1 (if available)
    TreeFam Gene Tree for ANKHD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKHD1 gene
    TANC22  ANKS32  ANKRD172  ANKRD292  FEM1A2  FANK12  KIDINS2202  RNASEL2  
    ANKHD1-EIF4EBP32  FEM1B2  TANC12  ANKS62  FEM1C2  
    18 SIMAP similar genes for ANKHD1 using alignment to 12 protein entries:     ANKH1_HUMAN (see all proteins):
    DKFZp586G1024    ANKHD1-EIF4EBP3    FLJ00246    ANKRD17    NOVA1    ANK2
    RAI14    IkBa    ANKDD1A    FANK1    GABPB1    PSMD10
    DKFZp434B2328    ANKRD29    ANKRD7    DKFZp761E1322    MTPN    ANKRD54

    ANKHD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    4 SNPs in ANKHD1 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0352934
    ----see VAR_0352932 N S mis40--------
    VAR_0352914
    ----see VAR_0352912 L M mis40--------
    VAR_0482814
    ----see VAR_0482812 G S mis40--------
    VAR_0352924
    ----see VAR_0352922 G C mis40--------

    HapMap Linkage Disequilibrium report for ANKHD1 (139781399 - 139929163 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ANKHD1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2418311CNV Deletion18987734
    nsv509090CNV Insertion20534489
    nsv330052CNV Loss16902084

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610500    OMIM disorders: --

    8 diseases for ANKHD1:    About MalaCards
    hemosiderosis    tracheal stenosis    respiratory failure    acute leukemia
    multiple myeloma    myeloma    schizophrenia    leukemia


    ANKHD1 for disorders           About GeneDecksing


    Export disorders for ANKHD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKHD1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with ANKHD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis. (PubMed id 16098192)1, 2, 3 Miles M.C....Ayyavoo V. (2005)
    2. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2, 3 Kikuno R....Ohara O. (1999)
    3. Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. (PubMed id 14557257)1, 2, 9 Poulin F.... Sonenberg N. (2003)
    4. ANKHD1, ankyrin repeat and KH domain containing 1, is overexpressed in acute leukemias and is associated with SHP2 in K562 cells. (PubMed id 16956752)1, 2 Traina F.... Saad S.T.O. (2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 3 Wiemann S.... Poustka A. (2001)
    7. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    8. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    9. ANKHD1 regulates cell cycle progression and proliferat ion in multiple myeloma cells. (PubMed id 23142581)1 Dhyani A....Olalla Saad S.T. (2012)
    10. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54882 HGNC: 24714 AceView: EIF4EBP3 Ensembl:ENSG00000131503 euGenes: HUgn54882
    ECgene: ANKHD1 H-InvDB: ANKHD1

    (According to HUGE)
    About This Section
    HUGE: KIAA1085

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKHD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKHD1 gene:
    Search GeneIP for patents involving ANKHD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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