ANKH Gene
protein-coding GIFtS: 56
GCID: GC05M014706
|
|
ankylosis, progressive homolog (mouse)(Previous names: ankylosis, progressive (mouse) homolog, craniometaphyseal...)
(Previous symbols: CCAL2, CMDJ)
| |
Aliases
for ANKH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankylosis, Progressive Homolog (Mouse)1 2 | | Ankylosis, Progressive (Mouse) Homolog1 | | ANK1 2 3 5 | | Craniometaphyseal Dysplasia, Jackson Type (Dominant)1 | | CCAL21 2 5 | | MANK2 | | CMDJ1 2 5 | | Progressive Ankylosis Protein Homolog2 | | CPPDD1 2 5 | | KIAA15813 | | HANK1 2 5 | | |
Export aliases for ANKH gene to outside databasesPrevious GC identifers: GC05M014695 GC05M014982 GC05M014757 GC05M014761 GC05M014762 GC05M014705 |
Summaries
for ANKH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ANKH:
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controlspyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has beensuggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. (provided by RefSeq,Jul 2008)
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1Function: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPitransporter
Gene Wiki entry for ANKH
|
Genomic Views
for ANKH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKH gene promoter:
GR NF-1 NF-1/L AML1a CUTL1 E47 Egr-2 FOXO4 GR-alpha ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKH
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKH |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p15.1 Ensembl cytogenetic band: 5p15.2 HGNC cytogenetic band: 5p15.2ANKH Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M014706: view genomic region
(about GC identifiers)
Start:
|
14,704,909 bp from pter |
End:
|
14,871,887 bp from pter |
Size:
|
166,979 bases |
Orientation:
|
minus strand |
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Proteins
for ANKH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1 (See
protein sequence)Recommended Name: Progressive ankylosis protein homolog Size: 492 amino acids; 54241 Da
Subcellular location: Membrane; Multi-pass membrane protein (Probable)
Sequence caution: Sequence=BAB13407.1; Type=Erroneous initiation;
Secondary accessions: B2RCA7 D3DTD4 Q9NQW2Explore the universe of human proteins at neXtProt for ANKH: NX_Q9HCJ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HCJ1
ANKH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_473368.1
ENSEMBL proteins: ENSP00000284268 ENSP00000426332 ENSP00000442524
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ANKH for ontologies About GeneDecksing
ANKH Antibody Products:
Assay Products for ANKH: |
Protein
Domains /
Families
for ANKH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKH for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9HCJ1ProtoNet protein and cluster: Q9HCJ1 1 Blocks protein family: IPB009887 Progressive ankylosis
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1Similarity: Belongs to the ANKH family |
Function
for ANKH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1Function: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPitransporter
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ANKH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKH |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKH |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005315 | inorganic phosphate transmembrane transporter activity |
IDA | 11326272 | | GO:0015114 | phosphate ion transmembrane transporter activity |
IEA | -- | | GO:0030504 | inorganic diphosphate transmembrane transporter activity |
IDA | 11326272 |
ANKH for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for ANKH:
Animal Models:
Mouse knock-out Anktm1.1Kng for ANKH
15 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Ank):
ANKH for phenotypes About GeneDecksing
|
Pathways & Interactions
for ANKH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ANKH
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ANKH (ENSP000002842684) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ANKH for ontologies About GeneDecksing
|
Drugs & Compounds
for ANKH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ANKH for compounds About GeneDecksing
 Browse Tocris compounds for ANKH
1 HMDB Compound for ANKH About this table
3 Novoseek chemical compound relationships for ANKH gene About this table
Search CenterWatch for drugs/clinical trials and news about ANKH
|
Transcripts
for ANKH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKH gene: NM_054027.4 Unigene Cluster for ANKH: Ankylosis, progressive homolog (mouse) Hs.156727 [show with all ESTs]Unigene Representative Sequence: NM_0540278 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000284268(uc003jfm.4) ENST00000502585 ENST00000503939 ENST00000515517
ENST00000513115 ENST00000503389 ENST00000505140 ENST00000535119
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ANKH (NM_017747) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKH | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKH |
Additional cDNA sequence: AB046801.1 AF274753.1 AK001799.1 AK054966.1 AK130112.1 AK130676.1 AK222631.1 AK315012.1 AL833238.1 AY358503.1 BC009835.2 BC014526.2 22 DOTS entries: DT.95302669 DT.105516 DT.448099 DT.91779733 DT.95302721 DT.97803887 DT.101970914 DT.40210918 DT.95302545 DT.40232332 DT.95104406 DT.100645433 DT.100786585 DT.100786586 DT.120815309 DT.95250382 DT.100637592 DT.100736158 DT.209965 DT.75188447 DT.91748403 DT.95189296 24/378 AceView cDNA sequences (see all 378): NM_054027 AA007428 BQ899362 BQ955342 AK130676 N90069 AI346315 AA593544 BM547717 CR613693 CK819937 BM710831 BU618635 F11358 AA324612 BF810455 AI978563 CB158823 AA252608 BF056362 BE876197 AI309218 BE673046 BU151082
GeneLoc Exon Structure
|
Expression
for ANKH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ANKH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKH
SOURCE GeneReport for Unigene cluster: Hs.156727
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1Tissue specificity: Found in osteoblasts from mandibular bone and from iliac bone; not detected in osteoclastic cells
SABiosciences Custom PCR Arrays for ANKH
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKH
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANKH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKH | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKH |
Orthologs
for ANKH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANKH gene from 5/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ank1 , 5 |
progressive ankylosis1, 5 |
89.57(n)1
98.37(a)1 |
|
15 (10.23 cM)5
117321 NM_020332.41 NP_065065.31
274666775 |
chicken
(Gallus gallus) |
Aves |
ANKH1 |
ankylosis, progressive homolog (mouse) |
83.4(n)
95.73(a) |
|
420917 NM_001012562.1 NP_001012580.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ANKH6 |
-- |
94(a) |
1 ↔ 1 |
4(60703795-60767671) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.119732 |
Xenopus laevis mRNA for progressive ankylosis-like protein (ank gene) less |
77.15(n) |
|
AJ302033.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
ankh2 |
ankylosis, progressive homolog |
77.63(n) |
|
323738 AJ302035.1 |
ENSEMBL Gene Tree for ANKH (if available)
TreeFam Gene Tree for ANKH (if available) |
Paralogs
for ANKH gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ANKH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANKH (14704909 - 14871887 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ANKH
1 CNV: 69017
Human Gene Mutation Database (HGMD): ANKH
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKH |
|
Disorders
/ Diseases
for ANKH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANKH for disorders About GeneDecksing
OMIM gene information: 605145
OMIM disorders: 123000 118600
UniProtKB/Swiss-Prot: ANKH_HUMAN, Q9HCJ1
Defects in ANKH are the cause of chondrocalcinosis 2 (CCAL2) [MIM:118600]. Chondrocalcinosis is a common causeof joint pain and arthritis caused by calcium deposition in articular cartilage and the presence of calciumhypophosphate crystals in synovial fluid, cartilage and periarticular soft tissue. CCAL2 inheritance is autosomaldominant Defects in ANKH are the cause of craniometaphyseal dysplasia Jackson type (CMDJ) [MIM:123000]. CMDJ is a rareautosomal dominant skeletal disorder characterized by abnormal bone formation and mineralization in membranous as wellas endochondral bones. Progressive thickening of the bones can cause narrowing of cranial foramina and can lead tosevere visual and neurological impairment, such as facial palsy and deafness
20/27  diseases for ANKH (see all 27): About MalaCardscraniometaphyseal dysplasia ankylosis craniometaphyseal dysplasia, autosomal dominant arthritis
pseudogout chondrocalcinosis 2 facial paralysis metaphyseal dysplasia
craniosynostosis calcinosis ankylosing spondylitis spondylitis
hypophosphatasia arthropathy hearing loss dilated cardiomyopathy
paralysis craniosynostosis, syndromic hypophosphatemia obesity, association with
4 diseases from the University of Copenhagen DISEASES database for ANKH:Craniometaphyseal dysplasia Pseudogout Ankylosis Hypophosphatasia 10/13 Novoseek disease relationships for ANKH gene (see all 13) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| calcium pyrophosphate dihydrate deposition disease |
94.7 |
10 |
13130483 (2), 12297987 (2), 12707589 (2), 15474385 (2) (see all 5) |
| chondrocalcinosis |
92.5 |
21 |
15818664 (8), 12297987 (1), 12744818 (1), 11981328 (1) (see all 8) |
| calcium pyrophosphate dihydrate deposition |
91.1 |
2 |
18034874 (1) |
| calcium pyrophosphate dihydrate crystal deposition disease |
83.5 |
4 |
13130483 (2), 19088867 (1), 12483726 (1) |
| arthrodesis |
79 |
21 |
15601852 (2), 18728347 (2), 10813297 (1), 19419319 (1) (see all 14) |
| pseudogout |
73.8 |
1 |
15818664 (1) |
| calcinosis |
69.4 |
1 |
11326272 (1) |
| arthropathy |
61.8 |
4 |
17563703 (2), 12297987 (1), 9635372 (1) |
| calcification |
52 |
10 |
15023384 (3), 16462526 (3), 15569637 (2) |
| osteoarthritis |
48.4 |
7 |
15023384 (3), 16462526 (1) |
GeneTests: ANKH
Craniometaphyseal Dysplasia
Genetic Association Database (GAD): ANKH
Human Genome Epidemiology (HuGE) Navigator: ANKH (12 documents)
Export disorders for ANKH gene to outside databases
|
Publications
for ANKH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKH gene, integrated from 9 sources (see all 83):
(articles sorted by number of sources associating them with ANKH) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH. (PubMed id 12297989)1, 2, 3, 9 Williams C.J.... Brown M.A. (2002)
- Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK. (PubMed id 11326338)1, 2, 3, 9 Reichenberger E....Olsen B.R. (2001)
- Role of the mouse ank gene in control of tissue calcification and arthritis. (PubMed id 10894769)1, 2, 3 Ho A.M.... Kingsley D.M. (2000)
- Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. (PubMed id 15818664)1, 4, 9 Zhang Y....Brown M.A. (2005)
- Mutations in ANKH cause chondrocalcinosis. (PubMed id 12297987)1, 2, 9 Pendleton A.... Kingsley D.M. (2002)
- Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease. (PubMed id 13130483)1, 2, 9 Williams C.J.... Ryan L.M. (2003)
- Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia. (PubMed id 11326272)1, 2, 9 Nuernberg P.... Tinschert S. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Investigation of the role of ANKH in ankylosing spondylitis. (PubMed id 14558096)1, 4 Timms A.E....Brown M.A. (2003)
|
External Searches for ANKH gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ANKH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKH gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ANKH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKH | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for ANKH | Genetics and Cytogenetics in Oncology and Haematology | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ANKH |
|
| | |
About This Section
| Patent Information for ANKH gene:
Search GeneIP for patents involving ANKH
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ANKH | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANKH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKH | | | OriGene Protein Over-expression Lysate for ANKH | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANKH | | OriGene 3'-UTR Clone for ANKH | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKH | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANKH | | OriGene Custom Protein Services for ANKH | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKH | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKH | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKH | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKH |
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| | | | Search Tocris compounds for ANKH |
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 | | | ANKH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKH |
|  |  |  | | | | ThermoFisher Antibody for ANKH |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKH |
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