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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKFY1 Gene

protein-coding   GIFtS: 51
GCID: GC17M004013

Ankyrin Repeat And FYVE Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat And FYVE Domain Containing 11 2     ZFYVE142
Ankyrin Repeats Hooked To A Zinc Finger Motif2 3     Ankyrin Repeat And FYVE Domain-Containing Protein 12
ANKHZN2 3     Ankyrin Repeat Hooked To Zinc Finger Motif2
BTBD232     KIAA12553
Rabankyrin-52     

External Ids:    HGNC: 207631   Entrez Gene: 514792   Ensembl: ENSG000001857227   OMIM: 6079275   UniProtKB: Q9P2R33   

Export aliases for ANKFY1 gene to outside databases

Previous GC identifers: GC17M004410 GC17M004019 GC17M004273


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANKFY1 Gene:
This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its
N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein
belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport.
Alternate splicing results in multiple transcript variants of this gene. (provided by RefSeq, Apr 2012)

GeneCards Summary for ANKFY1 Gene: 
ANKFY1 (ankyrin repeat and FYVE domain containing 1) is a protein-coding gene. Diseases associated with ANKFY1 include spasticity, and ataxia. GO annotations related to this gene include protein binding and metal ion binding. An important paralog of this gene is TNKS2.

Gene Wiki entry for ANKFY1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANKFY1 gene promoter:
         AhR   HOXA3   AP-1   p53   Arnt   Evi-1   E2F   E2F-1   HFH-1   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKFY1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ANKFY1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKFY1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

ANKFY1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKFY1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M004013:  view genomic region     (about GC identifiers)

Start:
4,066,665 bp from pter      End:
4,167,274 bp from pter
Size:
100,610 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANFY1_HUMAN, Q9P2R3 (See protein sequence)
Recommended Name: Ankyrin repeat and FYVE domain-containing protein 1  
Size: 1169 amino acids; 128399 Da
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein. Note=Also associated with
endosomal membranes
Sequence caution: Sequence=AAH52308.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAA86569.2;
Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8KA65 Q5RKV4 Q9ULG5
Alternative splicing: 3 isoforms:  Q9P2R3-1   Q9P2R3-2   Q9P2R3-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANKFY1: NX_Q9P2R3

Explore proteomics data for ANKFY1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P2R3

  • ANKFY1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANKFY1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001244928.1  NP_057460.3  

    ENSEMBL proteins: 
     ENSP00000343362   ENSP00000459943   ENSP00000459775   ENSP00000460619   ENSP00000467522  
     ENSP00000459247   ENSP00000416005  

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    Cloud-Clone Corp. Proteins for ANKFY1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IDA17897319
    GO:0010008endosome membrane ISS--
    GO:0043231intracellular membrane-bounded organelle IDA--

    ANKFY1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZFYVE: Zinc fingers, FYVE domain containing
    BTBD: BTB/POZ domain containing
    ANKRD: Ankyrin repeat domain containing

    5/9 InterPro protein domains (see all 9):
     IPR011333 BTB/POZ_fold
     IPR000306 Znf_FYVE
     IPR013069 BTB_POZ
     IPR017455 Znf_FYVE-rel
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q9P2R3

    ProtoNet protein and cluster: Q9P2R3

    3 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB000306 Zn-finger
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ANFY1_HUMAN, Q9P2R3
    Similarity: Contains 21 ANK repeats
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 1 FYVE-type zinc finger


    ANKFY1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0046872metal ion binding IEA--
         
    ANKFY1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ANKFY1:
     Increased cell death HMECs cel  Increased gamma-H2AX phosphory 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKFY1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/22 Interacting proteins for ANKFY1 (Q9P2R31, 3 ENSP000003433624) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GABARAPL2P605201, 3EBI-2513908,EBI-720116 I2D: score=1 
    GBASO753233, ENSP000003130504I2D: score=3 STRING: ENSP00000313050
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    MAP1LC3CQ9BXW43, ENSP000003497854I2D: score=1 STRING: ENSP00000349785
    USPL1Q5W0Q73, ENSP000002553044I2D: score=2 STRING: ENSP00000255304
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANKFY1 (ANFY1)

    Search CenterWatch for drugs/clinical trials and news about ANKFY1 / ANFY1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANKFY1 gene (3 alternative transcripts): 
    NM_001257999.1  NM_016376.3  NM_020740.2  

    Unigene Cluster for ANKFY1:

    Ankyrin repeat and FYVE domain containing 1
    Hs.696087  [show with all ESTs]
    Unigene Representative Sequence: CR933717
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000341657(uc002fxn.3 uc002fxo.3 uc002fxp.3 uc010ckp.3 uc002fxq.1)
    ENST00000570535 ENST00000574367 ENST00000572412 ENST00000575298 ENST00000572564
    ENST00000571547 ENST00000574736 ENST00000573722 ENST00000575509 ENST00000570934
    ENST00000573250 ENST00000575955(uc010vrz.2) ENST00000433651(uc002fxr.3)

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    8/117 QIAGEN miScript miRNA Assays for microRNAs that regulate ANKFY1 (see all 117):
    hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-106a hsa-miR-200a hsa-miR-3921 hsa-miR-759 hsa-miR-519a hsa-miR-3916
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    Additional mRNA sequence: 

    AB033081.2 AB073897.1 AK025483.1 AK025717.1 AK025960.1 AK057047.1 AK074324.1 AK094320.1 
    AK225170.1 AK292930.1 AK302712.1 BC052308.1 BC060812.1 CR933717.1 NR_047571.1 

    19 DOTS entries:

    DT.91763362  DT.444923  DT.91998076  DT.95178028  DT.100793517  DT.99969865  DT.100793508  DT.95211362 
    DT.99927551  DT.100014176  DT.120970252  DT.75127037  DT.97763345  DT.120970259  DT.201586  DT.92049922 
    DT.95162439  DT.75100663  DT.97765949 

    24/226 AceView cDNA sequences (see all 226):

    CA774507 BF380878 CB851615 BP371277 CN479607 AK025483 BQ638945 BQ438808 
    CB054536 BE550945 AA399607 AW295994 AI783513 AI630341 BI789249 AW450283 
    BU623663 BE674137 AI420179 CD172458 CB128158 AI277236 BM477612 BM974184 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ANKFY1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19 ^
    SP1:                                            -                                         -           -                                               -         
    SP2:                    -     -                 -                                         -           -                                               -         
    SP3:                                            -                                                                                                               
    SP4:        -                                   -                                                                                                               
    SP5:                          -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -   

    ExUns: 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:  -                                                         


    ECgene alternative splicing isoforms for ANKFY1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKFY1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAGACACTT
    ANKFY1 Expression
    About this image


    See ANKFY1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANKFY1

    SOURCE GeneReport for Unigene cluster: Hs.696087

    UniProtKB/Swiss-Prot: ANFY1_HUMAN, Q9P2R3
    Tissue specificity: High expression in whole adult brain and intermediate expression in all other tissues and
    specific brain regions examined, including fetal brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ANKFY1 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankfy11 , 5 ankyrin repeat and FYVE domain containing 11, 5 87.8(n)1
    95.04(a)1
      11 (44.47 cM)5
    117361  NM_009671.51  NP_033801.41 
     726900065 
    chicken
    (Gallus gallus)
    Aves ANKFY11 ankyrin repeat and FYVE domain containing 1 79.2(n)
    91.01(a)
      417494  XM_415742.3  XP_415742.3 
    lizard
    (Anolis carolinensis)
    Reptilia ANKFY16
    ankyrin repeat and FYVE domain containing 1
    85(a)
    1 ↔ 1
    GL343393.1(281682-312941)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.96572 Xenopus laevis transcribed sequence with moderate similarity more 79.33(n)    BX853285.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.1042 Transcribed sequence with weak similarity to protein more 76.82(n)    57046048 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG410991 CG41099 49.97(n)
    44.84(a)
      3355072  NM_001110981.1  NP_001104451.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F22G12.41 Protein F22G12.4 44.79(n)
    35.14(a)
      173180  NM_060904.2  NP_493305.1 


    ENSEMBL Gene Tree for ANKFY1 (if available)
    TreeFam Gene Tree for ANKFY1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKFY1 gene
    TNKS22  ANK32  TRPA12  ANK12  ANKRD522  TNKS2  ANKRD652  ANKRD502  
    INVS2  ANK22  ANKRD282  
    1 SIMAP similar gene for ANKFY1 using alignment to 4 protein entries:     ANFY1_HUMAN (see all proteins):
    DKFZp686M19106

    ANKFY1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2303 SNPs in ANKFY1 are shown (see all 2303)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1180153141,2
    F--4066175(+) CAGCTC/TATGAA 3 -- ds50011Minor allele frequency- T:0.02EA 120
    rs1124577451,2
    C,F--4066191(+) AAGCAG/CAACTA 3 -- ds50011Minor allele frequency- C:0.05WA 118
    rs72228601,2
    C,F,A,H--4066223(+) TGGGCA/GAACGT 3 -- ds500122Minor allele frequency- G:0.13NS EA NA WA 2646
    rs1880071781,2
    --4066238(+) AAGTTA/GATGTG 3 -- ds50010--------
    rs1815309151,2
    --4066287(+) ACAGCA/GTGGTT 3 -- ds50010--------
    rs1862602391,2
    --4066289(+) AGCGTA/GGTTAG 3 -- ds50010--------
    rs1920751631,2
    --4066329(+) ATTACG/TTGGGA 3 -- ds50010--------
    rs47905791,2
    C,F,A,H--4066404(+) ATGAGT/CTCTAT 3 -- ds500117Minor allele frequency- C:0.48NS EA NA WA 1126
    rs47905801,2
    C,F,A,H--4066519(+) GGTAGC/TGATTT 3 -- ds500124Minor allele frequency- T:0.12NA NS EA WA CSA 1602
    rs47905811,2
    C,F,A,H--4066657(+) TCCTCC/TTGAGA 3 -- ds500125Minor allele frequency- T:0.50NS EA NA WA CSA 2709

    HapMap Linkage Disequilibrium report for ANKFY1 (4066665 - 4167274 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for ANKFY1 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2715549CNV Deletion23290073
    esv1497662CNV Deletion17803354
    esv988491CNV Deletion20482838
    esv2471538CNV Deletion19546169
    esv2715550CNV Deletion23290073
    nsv1951CNV Insertion18451855
    esv25467CNV Loss19812545
    esv2751682CNV Gain17911159
    dgv173n21CNV Gain19592680
    nsv833344CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607927    OMIM disorders: --

    2 diseases for ANKFY1:    About MalaCards
    spasticity    ataxia


    ANKFY1 for disorders           About GeneDecksing


    Export disorders for ANKFY1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKFY1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with ANKFY1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization and chromosomal mapping of a novel human gene, ANKHZN. (PubMed id 10940552)1, 2, 3 Kuriyama H.... Kuwano R. (2000)
    2. A novel locus for autosomal recessive spastic ataxia on chromosome 17p. (PubMed id 17273843)1, 3 Bouslam N....Stevanin G. (2007)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    5. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (1999)
    6. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)
    7. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    8. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    9. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function. (PubMed id 22284051)1 Zhang J....Caplan S. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51479 HGNC: 20763 AceView: ANKFY1 Ensembl:ENSG00000185722 euGenes: HUgn51479
    ECgene: ANKFY1 H-InvDB: ANKFY1

    (According to HUGE)
    About This Section
    HUGE: KIAA1255

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKFY1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKFY1 gene:
    Search GeneIP for patents involving ANKFY1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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