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Aliases for ANKEF1 Gene

Aliases for ANKEF1 Gene

  • Ankyrin Repeat And EF-Hand Domain Containing 1 2 3
  • Ankyrin Repeat Domain-Containing Protein 5 3 4
  • ANKRD5 3 4
  • Ankyrin Repeat And EF-Hand Domain-Containing Protein 1 3
  • Ankyrin Repeat Domain 5 2

External Ids for ANKEF1 Gene

Previous Symbols for ANKEF1 Gene

  • ANKRD5

Summaries for ANKEF1 Gene

GeneCards Summary for ANKEF1 Gene

ANKEF1 (Ankyrin Repeat And EF-Hand Domain Containing 1) is a Protein Coding gene. Diseases associated with ANKEF1 include colorectal cancer. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is RFXANK.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKEF1 Gene

Genomics for ANKEF1 Gene

Genomic Location for ANKEF1 Gene

Start:
9,986,126 bp from pter
End:
10,058,303 bp from pter
Size:
72,178 bases
Orientation:
Plus strand

Genomic View for ANKEF1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKEF1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKEF1 Gene

No data available for Regulatory Elements for ANKEF1 Gene

Proteins for ANKEF1 Gene

  • Protein details for ANKEF1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NU02-ANKE1_HUMAN
    Recommended name:
    Ankyrin repeat and EF-hand domain-containing protein 1
    Protein Accession:
    Q9NU02
    Secondary Accessions:
    • B3KUQ0
    • Q9H6Y9

    Protein attributes for ANKEF1 Gene

    Size:
    776 amino acids
    Molecular mass:
    86664 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15111.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ANKEF1 Gene

Proteomics data for ANKEF1 Gene at MOPED

Post-translational modifications for ANKEF1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKEF1 Gene

No data available for DME Specific Peptides for ANKEF1 Gene

Domains for ANKEF1 Gene

Gene Families for ANKEF1 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing
  • EFHAND :EF-hand domain containing

Protein Domains for ANKEF1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9NU02

UniProtKB/Swiss-Prot:

ANKE1_HUMAN
Domain:
  • Contains 1 EF-hand domain.:
    • Q9NU02
Similarity:
  • Contains 8 ANK repeats.:
    • Q9NU02
genes like me logo Genes that share domains with ANKEF1: view

No data available for Suggested Antigen Peptide Sequences for ANKEF1 Gene

Function for ANKEF1 Gene

Gene Ontology (GO) - Molecular Function for ANKEF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKEF1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKEF1 Gene

Localization for ANKEF1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKEF1 Gene

Pathways for ANKEF1 Gene

SuperPathways for ANKEF1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKEF1 Gene

None

No data available for Pathways by source for ANKEF1 Gene

Transcripts for ANKEF1 Gene

Unigene Clusters for ANKEF1 Gene

Ankyrin repeat and EF-hand domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKEF1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^
SP1:
SP2: -
SP3: - - -
SP4: - - - - - - -
SP5:
SP6: - - - -
SP7: - - -
SP8: - - -
SP9:
SP10: -

ExUns: 14
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for ANKEF1 Gene

GeneLoc Exon Structure for
ANKEF1
ECgene alternative splicing isoforms for
ANKEF1

Expression for ANKEF1 Gene

mRNA expression in normal human tissues for ANKEF1 Gene

mRNA differential expression in normal tissues according to GTEx for ANKEF1 Gene

This gene is overexpressed in Testis (11.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKEF1 Gene

SOURCE GeneReport for Unigene cluster for ANKEF1 Gene Hs.70903

genes like me logo Genes that share expressions with ANKEF1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKEF1 Gene

Orthologs for ANKEF1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKEF1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKEF1 36
  • 100 (a)
OneToOne
ANKRD5 35
  • 99.66 (n)
  • 99.61 (a)
cow
(Bos Taurus)
Mammalia ANKEF1 35
  • 86.41 (n)
  • 87.35 (a)
ANKEF1 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKEF1 35
  • 86.08 (n)
  • 87.37 (a)
ANKEF1 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankef1 35
  • 82.77 (n)
  • 85.53 (a)
Ankef1 16
Ankef1 36
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKEF1 36
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKEF1 36
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankef1 35
  • 82.64 (n)
  • 84.88 (a)
chicken
(Gallus gallus)
Aves ANKEF1 36
  • 59 (a)
OneToOne
LOC416735 35
  • 64.34 (n)
  • 58.71 (a)
lizard
(Anolis carolinensis)
Reptilia ANKEF1 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankef1 35
  • 63.9 (n)
  • 58.84 (a)
Str.17841 35
zebrafish
(Danio rerio)
Actinopterygii ankef1a 35
  • 56.57 (n)
  • 50.85 (a)
ankef1a 36
  • 49 (a)
OneToMany
ankef1b 36
  • 47 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG5846 36
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
OneToOne
Species with no ortholog for ANKEF1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKEF1 Gene

ENSEMBL:
Gene Tree for ANKEF1 (if available)
TreeFam:
Gene Tree for ANKEF1 (if available)

Paralogs for ANKEF1 Gene

Paralogs for ANKEF1 Gene

Selected SIMAP similar genes for ANKEF1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKEF1: view

Variants for ANKEF1 Gene

Sequence variations from dbSNP and Humsavar for ANKEF1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
VAR_024172 -
VAR_033500 -
VAR_033501 -
VAR_033502 -
VAR_035609 A breast cancer sample

Relevant External Links for ANKEF1 Gene

HapMap Linkage Disequilibrium report
ANKEF1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKEF1 Gene

Disorders for ANKEF1 Gene

(1) MalaCards Diseases for ANKEF1 Gene

Search for ANKEF1 Gene in MalaCards »
genes like me logo Genes that share disorders with ANKEF1: view

No data available for UniProtKB/Swiss-Prot for ANKEF1 Gene

Publications for ANKEF1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica. (PMID: 17142250) Raby B.A. … CeledA^n J.C. (Hum. Mol. Genet. 2007) 2 3
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3

Products for ANKEF1 Gene

Sources for ANKEF1 Gene

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