Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ANK1 Gene

protein-coding GIFtS: 64
GCID: GC08M041510

ankyrin 1, erythrocytic

(Previous symbol: ANK)

Explore 24 diseases affiliated with
ANK1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ankyrin 1, Erythrocytic¹ ²		SPH2² ⁵
ANK¹ ² ³		Ankyrin-1¹
SPH1¹ ²		Ankyrin-R³
Erythrocyte Ankyrin² ³		Ankyrin-R³
ANK-1² ³

External Ids:	HGNC: 492¹	Entrez Gene: 286²	Ensembl: ENSG00000029534⁷	OMIM: 612641⁵	UniProtKB: P16157³

Export aliases for ANK1 gene to outside databases

Previous GC identifers: GC08M042256 GC08M041539 GC08M041251 GC08M041528 GC08M041629 GC08M040038

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANK1:

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin

cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the

maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target

proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of

three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly

conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject

to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also

been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all

patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise

to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from

usage of an alternate promoter have also been identified. (provided by RefSeq, Dec 2008)

UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157

Function: Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band

4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin,

vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the

erythrocytes anion exchange protein; they retain most or all of these binding functions

Function: Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic

reticulum and myofibrils

Gene Wiki entry for ANK1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_167187.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ANK1 gene promoter:
TBP
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ANK1 promoter sequence

Search SABiosciences Chromatin IP Primers for ANK1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANK1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p11.1 Ensembl cytogenetic band: 8p11.21 HGNC cytogenetic band: 8p11.21

ANK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANK1 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M041510: view genomic region (about GC identifiers)

Start:	41,510,739 bp from pter	End:	41,754,280 bp from pter
Size:	243,542 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157 (See protein sequence)

Recommended Name: Ankyrin-1

Size: 1881 amino acids; 206265 Da

Subunit: Interacts with a number of integral membrane proteins and cytoskeletal proteins. Interacts (via N-terminus)

with SPTB/spectrin (beta chain). Interacts (via N-terminus ANK repeats) with SLC4A1/erythrocyte membrane protein band

3 (via cytoplasmic N-terminus). Also interacts with TTN/titin. Isoform Mu17 interacts with OBSCN isoform 3/obscurin.

Interacts with HIF1AN

Subcellular location: Isoform Er1: Cytoplasm, cytoskeleton. Note=Probably the other erythrocyte (Er) isoforms, are

located near the surface of erythrocytic plasma membrane

Subcellular location: Isoform Mu17: Membrane. Cytoplasm, myofibril, sarcomere, M line. Note=Colocalizes with OBSCN

isoform 3/obscurin at the M line in differentiated skeletal muscle cells

Subcellular location: Isoform Mu18: Sarcoplasmic reticulum (Probable)

Subcellular location: Isoform Mu19: Sarcoplasmic reticulum (Probable)

Subcellular location: Isoform Mu20: Sarcoplasmic reticulum (Probable)

Sequence caution: Sequence=AAB47805.1; Type=Erroneous gene model prediction;

6/8 PDB 3D structures from and Proteopedia for ANK1 (see all 8):

1N11 (3D)

2YQF (3D)

2YVI (3D)

3F59 (3D)

3KBT (3D)

3KBU (3D)

Secondary accessions: A0PJN8 A6NJ23 O43400 Q13768 Q53ER1 Q59FP2 Q8N604 Q99407

Alternative promoter usage, Alternative splicing: 22 isoforms: P16157-1 P16157-4 P16157-5 P16157-6 P16157-3 P16157-7 P16157-8 P16157-9

P16157-10 P16157-11 P16157-12 P16157-13 P16157-14 P16157-15 P16157-16 P16157-2

P16157-17 P16157-18 P16157-19 P16157-20 P16157-21 P16157-22 (Produced by alternative splicing)

Explore the universe of human proteins at neXtProt for ANK1: NX_P16157

Post-translational modifications:

Regulated by phosphorylation¹

Palmitoylated¹

Hydroxylated by HIF1AN at several asparagine and 1 aspartate residue within ANK repeat region. Hydroxylation seems to

increase the conformational stability of this region and may also modulate protein-protein interactions mediated by

the ANK repeat region¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P16157

ANK1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (8 alternative transcripts):

NP_000028.3 NP_001135917.1 NP_001135918.1 NP_065208.2 NP_065209.2 NP_065210.2 NP_065211.2 NP_065213.2

ENSEMBL proteins:

ENSP00000339620 ENSP00000289734 ENSP00000428750 ENSP00000430368 ENSP00000319123

ENSP00000430174 ENSP00000265709 ENSP00000297744 ENSP00000335031 ENSP00000428315

ENSP00000369082 ENSP00000380149 ENSP00000403589 ENSP00000380147 ENSP00000309131

Reactome Protein details: P16157
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: ANK1 OriGene Protein Over-expression Lysate: ANK1 OriGene Custom Protein Services for ANK1
	GenScript Custom Purified and Recombinant Proteins Services for ANK1
	Novus Biologicals ANK1 Protein Novus Biologicals ANK1 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ANK1

Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--
GO:0005856	cytoskeleton	NAS	1833445
GO:0005886	plasma membrane	NAS	9430667
GO:0014731	spectrin-associated cytoskeleton	IDA	379653
GO:0016020	membrane	--	--

ANK1 for ontologies About GeneDecksing

ANK1 Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of ANK1
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for ANK1
	GenScript Custom Superior Antibodies Services for ANK1
	Novus Biologicals ANK1 Antibodies
	Search for Antibodies for ANK1 at Abcam
	Uscn Antibodies for ANK1
	ThermoFisher Antibodies for ANK1

Assay Products for ANK1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ANK1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ANK1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ANK1 for domains About GeneDecksing

5 InterPro domains/families:

IPR011029 DEATH-like_dom

IPR000488 Death_domain

IPR000906 ZU5

IPR020683 Ankyrin_rpt-contain_dom

IPR002110 Ankyrin_rpt

Graphical View of Domain Structure for InterPro Entry P16157

ProtoNet protein and cluster: P16157

3 Blocks protein families:

IPB000488 Death domain

IPB000906 ZU5 domain

IPB002110 Ankyrin repeat signature

UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157

Domain: The 55 kDa regulatory domain is involved in regulating binding of SPTB/spectrin (beta chain) and

SLC4A1/erythrocyte membrane protein band 3

Domain: The ANK repeat region forms a spiral around a large central cavity and is involved in binding of ion

transporters

Domain: The tandem configuration of the two ZU5 and the UPA domains forms a structural supramodule termed ZZU. ZU5-1

mediates interaction with beta-spectrin, and the ZU5-1/UPA interface is required for ankyrin's function other than

binding to spectrin (By similarity)

Similarity: Contains 23 ANK repeats

Similarity: Contains 1 death domain

Similarity: Contains 2 ZU5 domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157

Function: Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band

4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin,

vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the

erythrocytes anion exchange protein; they retain most or all of these binding functions

Function: Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic

reticulum and myofibrils

Genatlas biochemistry entry for ANK1:

ankyrin 1,206kDa,erythrocyte membrane protein,intermediate filament associated protein (IFAP,type III),also expressed

in neural tissue and skeletal muscle

miRNA Products:		OriGene 3'-UTR Clone (see all 5): ANK1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANK1
		8/84 QIAGEN miScript miRNA Assays for microRNAs that regulate ANK1 (see all 84):
		hsa-miR-607 hsa-miR-128 hsa-miR-759 hsa-miR-4267 hsa-miR-10b* hsa-miR-877* hsa-miR-890 hsa-miR-149

		SwitchGear 3'UTR luciferase reporter plasmid: ANK1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANK1 (see all 7) OriGene shRNA RFP: ANK1 OriGene siRNA: ANK1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANK1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ANK1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1 (see all 11) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1 (see all 8) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 8): ANK1 (NM_020475)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANK1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANK1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ANK1
		Search LifeMap BioReagents cell lines for ANK1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANK1

Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005198	structural molecule activity	NAS	9430667
GO:0005200	structural constituent of cytoskeleton	TAS	8640229
GO:0005515	protein binding	IPI	379653
GO:0008093	cytoskeletal adaptor activity	TAS	11427698
GO:0019899	enzyme binding	TAS	11427698

ANK1 for ontologies About GeneDecksing

Animal Models:
14 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Ank1):

behavior/neurological	cardiovascular system	growth/size	hematopoietic system	homeostasis/metabolism
immune system	integument	liver/biliary system	mortality/aging	nervous system
pigmentation	renal/urinary system	reproductive system	skeleton

ANK1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Axon guidance

	Axon guidance	1.00			L1CAM interactions	0.39
	Developmental Biology	0.69

NrCAM interactions

NrCAM interactions

1.00

Neurofascin interactions

Neurofascin interactions

1.00

CHL1 interactions

CHL1 interactions

1.00

Interaction between L1 and Ankyrins

Interaction between L1 and Ankyrins

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ANK1

Rac1 Pathway

5/7 Reactome Pathways for ANK1 (see all 7)

	L1CAM interactions
	Developmental Biology
	Interaction between L1 and Ankyrins
	NrCAM interactions
	CHL1 interactions

ANK1 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ANK1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/27 Interacting proteins for ANK1 (P16157^{1, 2, 3} ENSP00000265709⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 27)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
OBSCN	Q5VST9-3¹, ENSP00000409493⁴	EBI-941819,EBI-941921 MINT-50079 MINT-50077 MINT-50078 MINT-50080 MINT-50083 I2D: score=3 STRING: ENSP00000409493
RHAG	Q02094³, ENSP00000360217⁴	I2D: score=2 STRING: ENSP00000360217
EPB42	P16452³, ENSP00000300215⁴	I2D: score=1 STRING: ENSP00000300215
NFASC	O94856³, ENSP00000353154⁴	I2D: score=1 STRING: ENSP00000353154
SPTA1	P02549³, ENSP00000357130⁴	I2D: score=1 STRING: ENSP00000357130

About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006779	porphyrin-containing compound biosynthetic process	IEA	--
GO:0006887	exocytosis	NAS	1833445
GO:0006888	ER to Golgi vesicle-mediated transport	IDA	18768923
GO:0007010	cytoskeleton organization	NAS	9430667
GO:0007165	signal transduction	IEA	--

ANK1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

ANK1 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ANK1
6 Novoseek chemical compound relationships for ANK1 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
phosphatidylethanolamine	29.2	2	15171729 (1), 9931302 (1)
phosphatidylserine	23.7	1	15746942 (1)
phosphatidylcholine	23.5	5	12175923 (1), 2170369 (1)
lipid	3.03	1	15171729 (1)
zinc	0	3	9819391 (2), 12913000 (1)
tyrosine	0	2	17428854 (1)

Search CenterWatch for drugs/clinical trials and news about ANK1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ANK1 gene (10 alternative transcripts):

NM_000037.3 NM_001142445.1 NM_001142446.1 NM_020475.2 NM_020476.2 NM_020477.2 NM_020478.4 NM_020480.4

NM_020479.2 NM_020481.2

Unigene Cluster for ANK1:

Ankyrin 1, erythrocytic

Hs.654438 [show with all ESTs]

Unigene Representative Sequence: NM_001142446

18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):

ENST00000347528(uc003xoj.3 uc003xok.3 uc003xol.3 uc003xom.3)

ENST00000289734(uc003xoh.3 uc003xoi.3) ENST00000522231 ENST00000522543

ENST00000314214 ENST00000520299 ENST00000265709 ENST00000348036 ENST00000524227

ENST00000335651 ENST00000518715 ENST00000518061 ENST00000524069 ENST00000521407

ENST00000379758 ENST00000396945 ENST00000457297(uc011lcl.2 uc003xod.3 uc003xoc.3 uc003xof.3)

ENST00000396942

miRNA Products:		OriGene 3'-UTR Clone (see all 5): ANK1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANK1
		8/84 QIAGEN miScript miRNA Assays for microRNAs that regulate ANK1 (see all 84):
		hsa-miR-607 hsa-miR-128 hsa-miR-759 hsa-miR-4267 hsa-miR-10b* hsa-miR-877* hsa-miR-890 hsa-miR-149

		SwitchGear 3'UTR luciferase reporter plasmid: ANK1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANK1 (see all 7) OriGene shRNA RFP: ANK1 OriGene siRNA: ANK1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANK1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1 (see all 11) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1 (see all 8) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 8): ANK1 (NM_020475)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANK1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANK1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANK1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ANK1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANK1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANK1

Additional cDNA sequence:

AB209418.1 AK126647.1 AK223578.1 BC007930.2 BC014467.1 BC030957.1 BC117121.1 BX647936.1

M28880.1 X16609.1

15 DOTS entries:

DT.100751174 DT.102844156 DT.91775389 DT.91775385 DT.91775421 DT.100671224 DT.102844157 DT.95141964

DT.100751175 DT.100745555 DT.446414 DT.91775424 DT.91849266 DT.75102807 DT.40113153

24/127 AceView cDNA sequences (see all 127):

BC030957 BQ718623 AA422077 AI420193 T58012 AA464755 CA433323 AA477644

AI801936 CA396213 AI092367 AA326571 AI659683 BM909053 BU192234 T28060

BC014467 AK126647 NM_000037 AI693242 X16609 AI630380 BU656434 AK129864

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ANK1 (see all 12) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19	^	20	^	21	^	22	^	23	^	24	^	25	^
SP1:																																															-
SP2:																																															-
SP3:
SP4:
SP5:

ExUns:	26a	·	26b	^	27a	·	27b	^	28	^	29a	·	29b	^	30	^	31	^	32	^	33	^	34	^	35	^	36	^	37	^	38	^	39	^	40	^	41	^	42	^	43	^	44a	·	44b	·	44c	·	44d	·	44e	^
SP1:	-		-																																						-		-		-		-		-		-
SP2:	-		-																																						-		-		-		-		-		-
SP3:	-		-																																						-		-		-		-		-		-
SP4:	-		-																																-						-		-		-		-		-		-
SP5:																																									-		-		-		-		-		-

ExUns:	45	^	46a	·	46b	·	46c	^	47a	·	47b	^	48a	·	48b	·	48c	·	48d	·	48e
SP1:					-		-
SP2:							-		-		-
SP3:					-		-		-		-
SP4:					-		-
SP5:

ECgene alternative splicing isoforms for ANK1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ANK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGCTTCCT

About this image

ANK1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Ovary

Skeletal Muscle

Mandibular Arch Muscles

Mononuclear Myocytes

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor T36 (Embryonic Progenitor Cell)

PureStem™ progenitor U31 (Embryonic Progenitor Cell)

See ANK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANK1

SOURCE GeneReport for Unigene cluster: Hs.654438

UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157

Tissue specificity: Isoform Mu17, isoform Mu18, isoform Mu19 and isoform Mu20 are expressed in skeletal muscle. Isoform

Br21 is expressed in brain

SABiosciences Custom PCR Arrays for ANK1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANK1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ANK1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANK1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANK1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANK1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ANK1 gene from 8/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ANK1¹	ankyrin 1, erythrocytic	77.58(n) 82.92(a)		396311 XM_424401.3 XP_424401.3
lizard (Anolis carolinensis)	Reptilia	ANK1⁶	--	79(a)	1 ↔ 1	GL343545.1(971-121593)
African clawed frog (Xenopus laevis)	Amphibia	BJ064997.1²	--	77.41(n)		BJ064997.1
zebrafish (Danio rerio)	Actinopterygii	LOC797662¹	ankyrin-1-like	67.84(n) 71.59(a)		797662 XM_003200863.1 XP_003200911.1
fruit fly (Drosophila melanogaster)	Insecta	Ank2³	cytoskeletal anchoring cytoskeletal protein binding	53(a) (best of 3)		66A10 --
worm (Caenorhabditis elegans)	Secernentea	Y71A12B.4³	--	30(a) (best of 2)		I(13910265-13921903) --
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G14230¹	hypothetical protein	41.68(n) 30.44(a)		831273 NM_121427.7 NP_196927.4
rice (Oryza sativa)	Liliopsida	Os02g0457500¹	hypothetical protein	42.13(n) 29.89(a)		4329284 NM_001053313.1 NP_001046778.1

ENSEMBL Gene Tree for ANK1 (if available)
TreeFam Gene Tree for ANK1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ANK1 gene

TANC2² TNKS2² ANKRD17² ANK3² ANKHD1² ANKRD52² ANKHD1-EIF4EBP3² TNKS²

ANKRD50² TANC1² INVS² ANKRD28² ANK2² ANKRD44²

18/25 SIMAP similar genes for ANK1 using alignment to 6 protein entries: ANK1_HUMAN (see all proteins) (see all similar genes):

hANK1 ANK3 GABPB1 DKFZp566P0524 ANK2 ANKRD44

IkBa ACAP3 CDKN2D PPP1R12A DKFZp686M09125 ANKRD54

PSMD10 DKFZp434B2328 DKFZp761E1322 MTPN ANKRD29 CDKN2C

ANK1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs112447985^1,2		--	40039014(+)	`GGCCTC/TTGGCG`	8	--	ut3¹		2		CSA WA	119
rs72638943^1,2	C,	--	40039137(+)	`GCAGCC/TCCACC`	8	--	ut3¹		2		CSA WA	120
rs3802314^1,2	C,F,H,	--	40039369(+)	`GCTCCA/TGGGGC`	8	--	ut3¹ ese³		4		NS EA	416
rs78203311^1,2	F,	--	40039427(+)	`CGCGAG/CGGCGG`	8	--	ut3¹		1		WA	118
rs692941^1,2	F	--	40039466(-)	`CTCCGC/GGCCAG`	8	--	ut3¹		3		NA	28
rs112189561^1,2		--	40039767(+)	`CACCAC/AGTTCA`	8	--	ut3¹		1		CSA	2
rs201295961^1,2	C	--	40040564(-)	`GGAAAA/GAAAAA`	8	--	ut3¹		0	--	--	--	--
rs112209933^1,2	C,	--	40040649(+)	`AAAAAC/-CCCAA`	8	--	ut3¹		1		CSA	2
rs72638944^1,2	C,	--	40040796(+)	`TTGCAA/GGAGGC`	8	--	ut3¹		3		CSA WA NA	240
rs74828008^1,2		--	40041162(+)	`CAGCCC/TGACTT`	8	--	int¹		1		NA	120

HapMap Linkage Disequilibrium report for ANK1 (41510739 - 41754280 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for ANK1
3 CNVs: 10251 95395 82583
1 Indel: 82584
Human Gene Mutation Database (HGMD): ANK1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANK1

DNA2.0 Custom Variant and Variant Library Synthesis for ANK1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ANK1 for disorders           About GeneDecksing

OMIM gene information: 612641
OMIM disorders: 182900
UniProtKB/Swiss-Prot: ANK1_HUMAN, P16157

Defects in ANK1 are a cause of spherocytosis type 1 (SPH1) [MIM:182900]; also called hereditary spherocytosis

type 1 (HS1). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by

numerous abnormally shaped erythrocytes which are generally spheroidal. Inheritance can be autosomal dominant or

recessive

20/24 diseases for ANK1 (see all 24): About MalaCards

spherocytosis hereditary spherocytosis contagious pustular dermatitis spherocytosis, type 1

hereditary elliptocytosis elliptocytosis ehrlichiosis hemolytic anemia

kallmann syndrome sickle cell disease cowpox smallpox

werner syndrome anemia vaccinia dermatitis

myopathy breast carcinoma colorectal cancer ischemia

3 diseases from the University of Copenhagen DISEASES database for ANK1:

Hereditary elliptocytosis Anemia Cowpox

6 Novoseek disease relationships for ANK1 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
spherocytosis hereditary	92.4	19	16518602 (2), 9470011 (2), 16617750 (1), 17128827 (1) (see all 14)
spherocytosis	82	4	9054656 (2), 8703812 (1), 12719424 (1)
human granulocytic ehrlichiosis	62.2	1	10921951 (1)
anemia hemolytic	57.9	2	9235914 (1)
erythroleukemia	28	1	12489996 (1)
tumors	4	2	11717987 (1), 7970728 (1)

Human Genome Epidemiology (HuGE) Navigator: ANK1 (5 documents)

Export disorders for ANK1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ANK1 gene, integrated from 9 sources (see all 159):
(articles sorted by number of sources associating them with ANK1)

Utopia: connect your pdf to the dynamic
world of online information

cDNA sequence for human erythrocyte ankyrin. (PubMed id 1689849)^{1, 2, 3, 9} Lambert S.... Palek J. (1990)
Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis. (PubMed id 8640229)^{1, 2, 9} Eber S.W.... Lux S.E. (1996)
Structure and organization of the human ankyrin-1 gene. Basis for complexity of pre-mRNA processing. (PubMed id 9235914)^{1, 2, 9} Gallagher P.G.... Forget B.G. (1997)
An alternate promoter directs expression of a truncated, muscle- specific isoform of the human ankyrin 1 gene. (PubMed id 9430667)^{1, 2, 9} Gallagher P.G. and Forget B.G. (1998)
Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin. (PubMed id 2141335)^{1, 2, 9} Davis L.H. and Bennett V. (1990)
Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. (PubMed id 2137557)^{1, 2, 9} Lux S.E.... Bennett V. (1990)
Asparagine and aspartate hydroxylation of the cytoske letal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor . (PubMed id 21177872)^{1, 2} Yang M....Schofield C.J. (2011)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles. (PubMed id 12527750)^{1, 2} Bagnato P.... Sorrentino V. (2003)
The hydrophilic domain of small ankyrin-1 interacts with the two N- terminal immunoglobulin domains of titin. (PubMed id 12444090)^{1, 2} Kontrogianni-Konstantopoulos A. and Bloch R.J. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 286	HGNC: 492	AceView: ANK1	Ensembl:ENSG00000029534	euGenes: HUgn286
ECgene: ANK1	H-InvDB: ANK1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ANK1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ANK1	Genetics and Cytogenetics in Oncology and Haematology
Wikipedia	http://en.wikipedia.org/wiki/Ankyrin

Intellectual Property for ANK1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ANK1 gene:
Search GeneIP for patents involving ANK1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section

	EMD Millipore Mono- and Polyclonal Antibodies for the study of ANK1
	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
	Browse for Gene Knock-down Tools from EMD Millipore
	Browse Small Molecules at EMD Millipore
	Browse Kits and Assays available from EMD Millipore

	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for ANK1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANK1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANK1
	OriGene Protein Over-expression Lysate for ANK1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for ANK1		OriGene 3'-UTR Clone for ANK1
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANK1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for ANK1		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for ANK1		OriGene Custom Protein Services for ANK1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANK1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANK1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANK1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANK1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANK1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANK1

	GenScript Custom Purified and Recombinant Proteins Services for ANK1		GenScript cDNA clones with any tag delivered in your preferred vector for ANK1
	GenScript Custom Assay Services for ANK1		GenScript Custom Superior Antibodies Services for ANK1
	GenScript Custom overexpressing Cell Line Services for ANK1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in ANK1 promoter
	Search Chromatin IP Primers for ANK1
	RT² qPCR Primer Assay in human, mouse, rat ANK1
	GNC Network for ANK1
	SABiosciences PCR Arrays including human, mouse, rat ANK1

Search Tocris compounds for ANK1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	ANK1 antibodies
	ANK1 proteins
	ANK1 lysates

	Search for Antibodies for ANK1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for ANK1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

ANK1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for ANK1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANK1

	SwitchGear 3'UTR luciferase reporter plasmids for ANK1
	SwitchGear Promoter luciferase reporter plasmids for ANK1

ThermoFisher Antibodies for ANK1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANK1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ANK1 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

ANK1 Gene

ankyrin 1, erythrocytic

Aliases
for ANK1 gene

Summaries
for ANK1 gene

Genomic Views
for ANK1 gene

Proteins
for ANK1 gene

Protein Domains /
Families
for ANK1 gene

Function
for ANK1 gene

Pathways & Interactions
for ANK1 gene

Drugs & Compounds
for ANK1 gene

Transcripts
for ANK1 gene

Expression
for ANK1 gene

Orthologs
for ANK1 gene

Paralogs
for ANK1 gene

Genomic Variants
for ANK1 gene

Disorders / Diseases
for ANK1 gene

Publications
for ANK1 gene

External Searches for ANK1 gene

Genome Databases showing ANK1 gene

Other Databases showing ANK1 gene

Specialized Databases showing ANK1 gene

Intellectual Property
for ANK1 gene

Products
for ANK1 gene

View Random Gene

Advanced Search

Export list of displayed genes

ANK1 Gene

ankyrin 1, erythrocytic

Aliasesfor ANK1 gene

Summariesfor ANK1 gene

Genomic Viewsfor ANK1 gene

Proteinsfor ANK1 gene

Protein Domains /Familiesfor ANK1 gene

Functionfor ANK1 gene

Pathways & Interactionsfor ANK1 gene

Drugs & Compoundsfor ANK1 gene

Transcriptsfor ANK1 gene

Expression for ANK1 gene

Orthologsfor ANK1 gene

Paralogsfor ANK1 gene

Genomic Variantsfor ANK1 gene

Disorders / Diseasesfor ANK1 gene

Publicationsfor ANK1 gene

External Searches for ANK1 gene

Genome Databases showing ANK1 gene

Other Databases showing ANK1 gene

Specialized Databases showing ANK1 gene

Intellectual Propertyfor ANK1 gene

Productsfor ANK1 gene

View Random Gene

Aliases
for ANK1 gene

Summaries
for ANK1 gene

Genomic Views
for ANK1 gene

Proteins
for ANK1 gene

Protein Domains /
Families
for ANK1 gene

Function
for ANK1 gene

Pathways & Interactions
for ANK1 gene

Drugs & Compounds
for ANK1 gene

Transcripts
for ANK1 gene

Expression
for ANK1 gene

Orthologs
for ANK1 gene

Paralogs
for ANK1 gene

Genomic Variants
for ANK1 gene

Disorders / Diseases
for ANK1 gene

Publications
for ANK1 gene

Intellectual Property
for ANK1 gene

Products
for ANK1 gene