Aliases for ANHX Gene
External Ids for ANHX Gene
- HGNC: 40024
- Entrez Gene: 647589
- Ensembl: ENSG00000227059
- UniProtKB: E9PGG2
Previous GeneCards Identifiers for ANHX Gene
- GC12M133796
Summaries for ANHX Gene
GeneCards Summary for ANHX Gene
ANHX (Anomalous Homeobox) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANHX Gene
Genomics for ANHX Gene
Regulatory Element Products
Genomic Location for ANHX Gene
- Chromosome:
- 12
- Start:
- 133,218,312 bp from pter
- End:
- 133,236,220 bp from pter
- Size:
- 17,909 bases
- Orientation:
- Minus strand
Genomic View for ANHX Gene
Genes around ANHX on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.33 by Ensembl
- 12q24.33 by Entrez Gene
- 12q24.33 by HGNC
ANHX Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANHX Gene
No data available for Regulatory Elements for ANHX Gene
Proteins for ANHX Gene
-
Protein details for ANHX Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- E9PGG2-ANHX_HUMAN
- Recommended name:
- Anomalous homeobox protein
- Protein Accession:
- E9PGG2
- Q96MC1
Protein attributes for ANHX Gene
- Size:
- 379 amino acids
- Molecular mass:
- 41695 Da
- Quaternary structure:
- No Data Available
Protein Expression for ANHX Gene
Post-translational modifications for ANHX Gene
Other Protein References for ANHX Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ANHX
- Novus Biologicals Antibodies for ANHX
-
Abcam antibodies for ANHX
- Search GeneTex for Antibodies for ANHX
Protein Products
-
OriGene Purified Proteins for ANHX
- Search Origene for MassSpec and Protein Over-expression Lysates for ANHX
- Origene Custom Protein Services for ANHX
- Search GeneTex for Proteins for ANHX
Assay Products
No data available for DME Specific Peptides for ANHX Gene
Domains & Families for ANHX Gene
Protein Domains for ANHX Gene
- InterPro:
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ANHX Gene
Function for ANHX Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0043565 | sequence-specific DNA binding | IEA | -- |
Phenotypes for ANHX Gene
- GenomeRNAi human phenotypes for ANHX:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANHX
-
- Search ViGene Biosciences for ANHX
CRISPR Products
-
OriGene CRISPR knockouts for ANHX
- GenScript: Design CRISPR guide RNA sequences for ANHX
miRNA Products
- Search ViGene Biosciences for ANHX
Inhibitory RNA Products
- Search ViGene Biosciences for ANHX
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ANHX
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANHX
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANHX Gene
Localization for ANHX Gene
Subcellular locations from UniProtKB/Swiss-Prot for ANHX Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for ANHX Gene
No Data Available
Interacting Proteins for ANHX Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ANHX Gene
Transcripts for ANHX Gene
mRNA/cDNA for ANHX Gene
- (8) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ANHX Gene
- Anomalous homeobox:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ANHX
- GenScript: Design CRISPR guide RNA sequences for ANHX
miRNA Products
- Search ViGene Biosciences for ANHX
Inhibitory RNA Products
- Search ViGene Biosciences for ANHX
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ANHX
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANHX
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for ANHX Gene
mRNA differential expression in normal tissues according to GTEx for ANHX Gene
This gene is overexpressed in Testis (x50.9).
This gene is overexpressed in Fetal ovary (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANHX Gene
NURSA nuclear receptor signaling pathways regulating expression of ANHX Gene:
ANHXSOURCE GeneReport for Unigene cluster for ANHX Gene:
Hs.703008Evidence on tissue expression from TISSUES for ANHX Gene
- Nervous system(2.1)
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANHX Gene
Orthologs for ANHX Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ANHX 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ANHX 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | LOC531406 34 |
|
||
| ANHX 35 |
|
OneToOne | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ANHX 35 |
|
OneToOne |
- Species where no ortholog for ANHX was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for ANHX Gene
No data available for Paralogs for ANHX Gene
Variants for ANHX Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000065447 | -- | 133,221,497(+) | TCCCT(C/G)GGCCT | intron-variant | |
| rs1000118965 | -- | 133,234,316(+) | CACAG(A/G)TGTCC | nc-transcript-variant, reference, missense | |
| rs1000137567 | -- | 133,231,618(+) | AACTC(C/T)TGGCT | nc-transcript-variant, reference, synonymous-codon | |
| rs1000154001 | -- | 133,236,441(+) | GTGGC(C/T)CCCTC | upstream-variant-2KB | |
| rs1000276879 | -- | 133,236,649(+) | GGTTT(A/G)TGGCT | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3550105 | CNV | deletion | 23714750 |
| esv3631333 | CNV | gain | 21293372 |
| esv3631335 | CNV | gain | 21293372 |
| nsv1129543 | CNV | tandem duplication | 24896259 |
| nsv952515 | CNV | deletion | 24416366 |
Gene Damage Index Score:
11.48;
92.89% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ANHX Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ANHX
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANHX Gene
Disorders for ANHX Gene
Relevant External Links for ANHX
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ANHX
No disorders were found for ANHX Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANHX Gene
Publications for ANHX Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
- The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4 64
- The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64
Products for ANHX Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for ANHX
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ANHX
- Search Origene for MassSpec and Protein Over-expression Lysates for ANHX
- Origene Custom Protein Services for ANHX
- Browse OriGene Inhibitory RNA Products For ANHX
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for ANHX
- OriGene ORF clones in human for ANHX
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for ANHX in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ANHX
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- GenScript Custom overexpressing Cell Line Services for ANHX
- GenScript: Design CRISPR guide RNA sequences for ANHX
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ANHX
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANHX
- VectorBuilder custom plasmid, inducible vectors for ANHX
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANHX
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ANHX Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer