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Aliases for ANHX Gene

Aliases for ANHX Gene

  • Anomalous Homeobox 2 3 5
  • Anomalous Homeobox Protein 3
  • HCG2007354 3

External Ids for ANHX Gene

Previous GeneCards Identifiers for ANHX Gene

  • GC12M133796

Summaries for ANHX Gene

GeneCards Summary for ANHX Gene

ANHX (Anomalous Homeobox) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding.

Additional gene information for ANHX Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANHX Gene

Genomics for ANHX Gene

Genomic Locations for ANHX Gene

Genomic Locations for ANHX Gene
17,909 bases
Minus strand

Genomic View for ANHX Gene

Genes around ANHX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANHX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANHX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANHX Gene

No data available for Regulatory Elements for ANHX Gene

Proteins for ANHX Gene

  • Protein details for ANHX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Anomalous homeobox protein
    Protein Accession:
    Secondary Accessions:
    • Q96MC1

    Protein attributes for ANHX Gene

    379 amino acids
    Molecular mass:
    41695 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANHX Gene

Post-translational modifications for ANHX Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANHX Gene

Domains & Families for ANHX Gene

Gene Families for ANHX Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANHX Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANHX: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ANHX Gene

Function for ANHX Gene

Gene Ontology (GO) - Molecular Function for ANHX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with ANHX: view

Phenotypes for ANHX Gene

GenomeRNAi human phenotypes for ANHX:
genes like me logo Genes that share phenotypes with ANHX: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANHX Gene

Localization for ANHX Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANHX Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANHX gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ANHX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ANHX: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ANHX Gene

Pathways & Interactions for ANHX Gene

No Data Available

Interacting Proteins for ANHX Gene

Gene Ontology (GO) - Biological Process for ANHX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ANHX: view

No data available for Pathways by source and SIGNOR curated interactions for ANHX Gene

Drugs & Compounds for ANHX Gene

No Compound Related Data Available

Transcripts for ANHX Gene

mRNA/cDNA for ANHX Gene

(8) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANHX Gene

Anomalous homeobox:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANHX Gene

No ASD Table

Relevant External Links for ANHX Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANHX Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANHX Gene

mRNA differential expression in normal tissues according to GTEx for ANHX Gene

This gene is overexpressed in Testis (x50.9).

Protein differential expression in normal tissues from HIPED for ANHX Gene

This gene is overexpressed in Fetal ovary (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANHX Gene

Protein tissue co-expression partners for ANHX Gene

NURSA nuclear receptor signaling pathways regulating expression of ANHX Gene:


SOURCE GeneReport for Unigene cluster for ANHX Gene:


Evidence on tissue expression from TISSUES for ANHX Gene

  • Nervous system(2.1)
genes like me logo Genes that share expression patterns with ANHX: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANHX Gene

Orthologs for ANHX Gene

This gene was present in the common ancestor of mammals.

Orthologs for ANHX Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANHX 33 34
  • 99.21 (n)
(Canis familiaris)
Mammalia ANHX 33 34
  • 77.81 (n)
(Bos Taurus)
Mammalia LOC531406 33
  • 77.1 (n)
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia ANHX 34
  • 52 (a)
Species where no ortholog for ANHX was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANHX Gene

Gene Tree for ANHX (if available)
Gene Tree for ANHX (if available)

Paralogs for ANHX Gene

No data available for Paralogs for ANHX Gene

Variants for ANHX Gene

Sequence variations from dbSNP and Humsavar for ANHX Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000065447 -- 133,221,497(+) TCCCT(C/G)GGCCT intron-variant
rs1000118965 -- 133,234,316(+) CACAG(A/G)TGTCC nc-transcript-variant, reference, missense
rs1000137567 -- 133,231,618(+) AACTC(C/T)TGGCT nc-transcript-variant, reference, synonymous-codon
rs1000154001 -- 133,236,441(+) GTGGC(C/T)CCCTC upstream-variant-2KB
rs1000276879 -- 133,236,649(+) GGTTT(A/G)TGGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ANHX Gene

Variant ID Type Subtype PubMed ID
nsv952515 CNV deletion 24416366
nsv1129543 CNV tandem duplication 24896259
esv3631335 CNV gain 21293372
esv3631333 CNV gain 21293372
esv3550105 CNV deletion 23714750

Variation tolerance for ANHX Gene

Gene Damage Index Score: 11.48; 92.89% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANHX Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANHX Gene

Disorders for ANHX Gene

Relevant External Links for ANHX

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANHX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANHX Gene

Publications for ANHX Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  3. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4 60
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60

Products for ANHX Gene

Sources for ANHX Gene

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