Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANGEL2 Gene

protein-coding   GIFtS: 45
GCID: GC01M213165

Angel Homolog 2 (Drosophila)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Angel Homolog 2 (Drosophila)1 2
KIAA0759L2 3
Protein Angel Homolog 22

External Ids:    HGNC: 305341   Entrez Gene: 908062   Ensembl: ENSG000001746067   UniProtKB: Q5VTE63   

Export aliases for ANGEL2 gene to outside databases

Previous GC identifers: GC01M209555 GC01M211232 GC01M183840


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ANGEL2 Gene: 
ANGEL2 (angel homolog 2 (Drosophila)) is a protein-coding gene. Diseases associated with ANGEL2 include leukemia. An important paralog of this gene is ANGEL1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANGEL2 gene promoter:
         Nkx3-1   Nkx3-1 v4   AML1a   NCX/Ncx   POU6F1 (c2)   Nkx3-1 v1   AREB6   Nkx3-1 v2   Nkx3-1 v3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANGEL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ANGEL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANGEL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q32.3

ANGEL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANGEL2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M213165:  view genomic region     (about GC identifiers)

Start:
213,165,524 bp from pter      End:
213,189,168 bp from pter
Size:
23,645 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANGE2_HUMAN, Q5VTE6 (See protein sequence)
Recommended Name: Protein angel homolog 2  
Size: 544 amino acids; 62339 Da
Sequence caution: Sequence=AAH47469.1; Type=Erroneous termination; Positions=456; Note=Translated as Ser;
Secondary accessions: B7Z2U4 D3DTA3 Q86X13 Q8NHH3
Alternative splicing: 2 isoforms:  Q5VTE6-1   Q5VTE6-2   

Explore the universe of human proteins at neXtProt for ANGEL2: NX_Q5VTE6

Explore proteomics data for ANGEL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VTE6

  • ANGEL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANGEL2 Protein Expression
    REFSEQ proteins: NP_653168.2  
    ENSEMBL proteins: 
     ENSP00000355929   ENSP00000353696   ENSP00000446124   ENSP00000443193   ENSP00000438141  

    Human Recombinant Protein Products for ANGEL2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ANGEL2
    OriGene Protein Over-expression Lysate for ANGEL2
    OriGene MassSpec for ANGEL2 
    OriGene Custom Protein Services for ANGEL2
    GenScript Custom Purified and Recombinant Proteins Services for ANGEL2
    Novus Biologicals ANGEL2 Protein
    Novus Biologicals ANGEL2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ANGEL2 


    ANGEL2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ANGEL2
    GenScript Custom Superior Antibodies Services for ANGEL2
    Novus Biologicals ANGEL2 Antibodies
    Abcam antibodies for ANGEL2
    Cloud-Clone Corp. Antibodies for ANGEL2 
    ThermoFisher Antibodies for ANGEL2
    LSBio Antibodies in human, mouse, rat for ANGEL2 

    Assay Products for ANGEL2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ANGEL2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ANGEL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ANGEL2 
    Cloud-Clone Corp. CLIAs for ANGEL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR005135 Endo/exonuclease/phosphatase

    Graphical View of Domain Structure for InterPro Entry Q5VTE6

    ProtoNet protein and cluster: Q5VTE6

    UniProtKB/Swiss-Prot: ANGE2_HUMAN, Q5VTE6
    Similarity: Belongs to the CCR4/nocturin family


    ANGEL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANGEL2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANGEL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANGEL2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ANGEL2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANGEL2
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate ANGEL2 (see all 25):
    hsa-miR-548j hsa-miR-607 hsa-miR-520d-5p hsa-miR-548i hsa-miR-429 hsa-miR-3613-3p hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidANGEL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANGEL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANGEL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ANGEL2
    Sirion Biotech Customized adenovirus for overexpression of ANGEL2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ANGEL2 (see all 7)
    OriGene ORF clones in mouse, rat for ANGEL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANGEL2 (NM_144567)
    Sino Biological Human cDNA Clone for ANGEL2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANGEL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANGEL2
    Sirion Biotech Customized lentivirus for stable overexpression of ANGEL2 
                         Customized lentivirus expression plasmids for stable overexpression of ANGEL2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ANGEL2
    Search LifeMap BioReagents cell lines for ANGEL2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANGEL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANGEL2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ANGEL2 (ENSP000003559294) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANGEL2 (ANGE2)

    Search CenterWatch for drugs/clinical trials and news about ANGEL2 / ANGE2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANGEL2 gene: 
    NM_144567.3  

    Unigene Cluster for ANGEL2:

    Angel homolog 2 (Drosophila)
    Hs.157078  [show with all ESTs]
    Unigene Representative Sequence: NM_144567
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366962(uc001hjz.3) ENST00000360506(uc010pto.2 uc010ptp.2 uc001hka.3 uc010ptq.2)
    ENST00000473303 ENST00000498650 ENST00000476904 ENST00000460337(uc001hkb.3)
    ENST00000481918 ENST00000540642 ENST00000544555 ENST00000535388
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANGEL2
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate ANGEL2 (see all 25):
    hsa-miR-548j hsa-miR-607 hsa-miR-520d-5p hsa-miR-548i hsa-miR-429 hsa-miR-3613-3p hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidANGEL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANGEL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANGEL2
    Clone
    Products:
         
    OriGene clones in human, mouse for ANGEL2 (see all 7)
    OriGene ORF clones in mouse, rat for ANGEL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANGEL2 (NM_144567)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANGEL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANGEL2
    Sirion Biotech Customized lentivirus for stable overexpression of ANGEL2 
                         Customized lentivirus expression plasmids for stable overexpression of ANGEL2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ANGEL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANGEL2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANGEL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANGEL2

    Additional mRNA sequence: 

    AF510741.1 AK022855.1 AK093947.1 AK294479.1 AK295116.1 AK299208.1 AK299365.1 AK310946.1 
    AK311276.1 AL079275.1 AY468376.1 BC016966.1 BC047469.1 

    12 DOTS entries:

    DT.305564  DT.213633  DT.453530  DT.86846208  DT.100023507  DT.99979564  DT.100673955  DT.75194345 
    DT.121412678  DT.40131661  DT.435467  DT.91958228 

    24/130 AceView cDNA sequences (see all 130):

    AY468376 AA872268 AA347971 CA437094 BF223265 AF510741 AA347972 AA948664 
    N73953 AA586312 BX476308 AI918547 BQ683375 AI658922 AI828833 BI769553 
    BG501123 BI089873 AK093947 AA483812 NM_144567 BU155475 H10366 AA337396 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ANGEL2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b
    SP1:                    -     -                             -                                   -           -                                 
    SP2:                                                                                                        -                                 
    SP3:                    -     -     -     -     -     -     -                                                                                 
    SP4:                          -                             -                                                                                 
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for ANGEL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANGEL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANGEL2 Expression
    About this image


    See ANGEL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANGEL2

    SOURCE GeneReport for Unigene cluster: Hs.157078
        SABiosciences Custom PCR Arrays for ANGEL2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ANGEL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANGEL2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANGEL2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANGEL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANGEL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ANGEL2 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Angel21 , 5 angel homolog 2 (Drosophila)1, 5 84.5(n)1
    85.48(a)1
      1 (96.28 cM)5
    524771  NM_021421.41  NP_067396.31 
     1909251125 
    chicken
    (Gallus gallus)
    Aves ANGEL21 angel homolog 2 (Drosophila) 70.48(n)
    69.19(a)
      421363  NM_001031047.1  NP_001026218.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANGEL26
    angel homolog 2 (Drosophila)
    56(a)
    1 ↔ 1
    1(238810538-238827433)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ640654.12   -- 73.22(n)    BJ640654.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufl78e022 wufl78e02 73.63(n)   334566  AL922534.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta angel6
    angel
    30(a)
    1 → many
    2R(19581521-19582755)
    worm
    (Caenorhabditis elegans)
    Secernentea W02G9.51 Protein W02G9.5 48.07(n)
    39.2(a)
      189127  NM_071324.4  NP_503725.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CCR46
    Component of the CCR4-NOT transcriptional complex,...
    12(a)
    1 → many
    I(110846-113359)


    ENSEMBL Gene Tree for ANGEL2 (if available)
    TreeFam Gene Tree for ANGEL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANGEL2 gene
    ANGEL12  CCRN4L2  PDE122  CNOT6L2  CNOT62  
    1 SIMAP similar gene for ANGEL2 using alignment to 4 protein entries:     ANGE2_HUMAN (see all proteins):
    ANGEL1

    ANGEL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/524 SNPs in ANGEL2 are shown (see all 524)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1470535031,2
    --213165465(+) GTAAAA/GGCAAC 1 -- int10--------
    rs1384107201,2
    --213165483(+) CTTATA/GCATCT 1 -- int10--------
    rs1159487661,2
    C--213165704(+) ATCTTC/GATAGC 1 -- ut310--------
    rs1824270051,2
    --213165777(+) ATAGTA/TTAACA 1 -- ut310--------
    rs1166413791,2
    C,F--213165794(+) ACTGAG/AAGATT 1 -- ut311Minor allele frequency- A:0.04WA 118
    rs1501958801,2
    --213165862(+) AGAGTG/TACCAA 1 -- ut310--------
    rs412771561,2
    C,F--213165907(+) AATTAT/CTTTTA 1 -- ut311Minor allele frequency- C:0.02NA 120
    rs1869918611,2
    --213166041(+) GCACAC/TGAAAA 1 -- ut310--------
    rs1142256631,2
    C,F--213166067(+) CAATAT/CATTAA 1 -- ut311Minor allele frequency- C:0.02WA 118
    rs412771581,2
    C,F--213166205(+) TTTTCA/GTTTTT 1 -- ut315Minor allele frequency- G:0.38WA CSA NA 244

    HapMap Linkage Disequilibrium report for ANGEL2 (213165524 - 213189168 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ANGEL2: --

    Human Gene Mutation Database (HGMD): ANGEL2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ANGEL2
    DNA2.0 Custom Variant and Variant Library Synthesis for ANGEL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ANGEL2:    About MalaCards
    leukemia    


    ANGEL2 for disorders           About GeneDecksing


    Export disorders for ANGEL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANGEL2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ANGEL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. (PubMed id 11943475)1, 3 Lipovich L.... Quigley J.G. (2002)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90806 HGNC: 30534 AceView: LOC90806 Ensembl:ENSG00000174606 euGenes: HUgn90806
    ECgene: ANGEL2 H-InvDB: ANGEL2

    (According to HUGE)
    About This Section
    HUGE: KIAA0759L

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANGEL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANGEL2 gene:
    Search GeneIP for patents involving ANGEL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ANGEL2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ANGEL2  
     OriGene MassSpec something-or-other for ANGEL2   OriGene clones in human, mouse for ANGEL2  
     OriGene qSTAR qPCR primer pairs in human, mouse for ANGEL2   OriGene Purified Protein for ANGEL2  
     OriGene ORF clones in mouse, rat for ANGEL2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ANGEL2   OriGene Custom Protein Services for ANGEL2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANGEL2
     QIAGEN SeqTarget long-range PCR primers for resequencing ANGEL2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANGEL2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANGEL2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANGEL2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANGEL2
     GenScript Custom Purified and Recombinant Proteins Services for ANGEL2 GenScript cDNA clones with any tag delivered in your preferred vector for ANGEL2
     GenScript Custom Assay Services for ANGEL2 GenScript Custom Superior Antibodies Services for ANGEL2
     GenScript Custom overexpressing Cell Line Services for ANGEL2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ANGEL2 promoter
     Search Chromatin IP Primers for ANGEL2
     RT2 qPCR Primer Assay in human, mouse, rat ANGEL2
     Search GNC Networks for ANGEL2
     SABiosciences Custom PCR Arrays for ANGEL2
     Search Tocris compounds for ANGEL2 (ANGE2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ANGEL2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ANGEL2 antibodies
     ANGEL2 proteins
     ANGEL2 lysates
     Antibodies for ANGEL2
     See all of Abcam's Antibodies, Kits and Proteins for ANGEL2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ANGEL2
     Antibodies for ANGEL2
     ELISAs for ANGEL2
     CLIAs for ANGEL2
     Search LifeMap BioReagents cell lines for ANGEL2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANGEL2
     SwitchGear 3'UTR luciferase reporter plasmids for ANGEL2
     SwitchGear Promoter luciferase reporter plasmids for ANGEL2
     ThermoFisher Antibodies for ANGEL2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANGEL2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ANGEL2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANGEL2
    Customized:
     lentivirus for stable overexpression of ANGEL2
     lentivirus expression plasmids for stable overexpression of ANGEL2
     adenovirus for overexpression of ANGEL2
     LSBio Antibodies in human, mouse, rat for ANGEL2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ANGEL2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4