ANAPC4 Gene
protein-coding GIFtS: 54
GCID: GC04P025462
|
|
anaphase promoting complex subunit 4
| |
Aliases for ANAPC4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Anaphase Promoting Complex Subunit 41 2 | | APC41 2 3 5 | | Cyclosome Subunit 42 3 | | Anaphase-Promoting Complex Subunit 42 |
Export aliases for ANAPC4 gene to outside databasesPrevious GC identifers: GC04P025067 GC04P025129 GC04P025055 GC04P024719 |
Summaries for ANAPC4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ANAPC4: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphasetransition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which aresubsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eightsubunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of thisgene product is not known. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: APC4_HUMAN, Q9UJX5Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains Gene Wiki entry for ANAPC4
|
Genomic Views for ANAPC4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006316.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ANAPC4 gene promoter: USF1 AML1a POU3F1 Ik-3 MEF-2A POU2F1 USF-1 POU2F1a aMEF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for ANAPC4
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANAPC4 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p15.2 Ensembl cytogenetic band: 4p15.2 HGNC cytogenetic band: 4p15.31ANAPC4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P025462: view genomic region
(about GC identifiers)
Start:
|
25,378,835 bp from pter |
End:
|
25,420,120 bp from pter |
Size:
|
41,286 bases |
Orientation:
|
plus strand |
|
Proteins for ANAPC4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: APC4_HUMAN, Q9UJX5 (See
protein sequence)Recommended Name: Anaphase-promoting complex subunit 4 Size: 808 amino acids; 92116 Da
Subunit: The APC/C is composed of at least 12 subunits
Secondary accessions: A8K8H1 Q6PCC6 Q9NSH6Alternative splicing: 2 isoforms: Q9UJX5-1 Q9UJX5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ANAPC4: NX_Q9UJX5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UJX5 ANAPC4 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_037499.2 ENSEMBL proteins: ENSP00000318775 ENSP00000426654 ENSP00000426512 ENSP00000421840 Reactome Protein details: Q9UJX5 Human Recombinant Protein Products for ANAPC4:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ANAPC4 for ontologies About GeneDecksing
ANAPC4 Antibody Products: Assay Products for ANAPC4: |
Protein
Domains / Families for ANAPC4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANAPC4 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9UJX5ProtoNet protein and cluster: Q9UJX5 UniProtKB/Swiss-Prot: APC4_HUMAN, Q9UJX5Similarity: Belongs to the APC4 family |
Function for ANAPC4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: APC4_HUMAN, Q9UJX5Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | ubiquitin-protein ligase activity |
TAS | 6180011 | | GO:0019903 | protein phosphatase binding |
IPI | -- |
ANAPC4 for ontologies About GeneDecksing
Phenotypes: 4 GenomeRNAi human phenotypes for ANAPC4: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ANAPC4 (NM_013367) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANAPC4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC4  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC4 |
|
Pathways & Interactions for ANAPC4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/22 super-pathways (see all 22) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitinated Orc1 is degraded by the proteasome | | | 2 | APC-Cdc20 mediated degradation of Nek2A | | | 3 | M Phase | | | 4 | Antigen processing: Ubiquitination & Proteasome degradation | | | 5 | Cell cycle_Spindle assembly and chromosome separation | |
Pathway sources See GeneCards unified pathways Show all pathways
5/9 EMD Millipore Pathways for ANAPC4 (see all 9) 5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ANAPC4 (see all 6) 5/7 GeneGo (Thomson Reuters) Pathways for ANAPC4 (see all 7) 1 BioSystems Pathway for ANAPC4 
5/36
Reactome Pathways for ANAPC4 (see all 36)
4
Kegg Pathways (Kegg details for ANAPC4): UniProtKB/Swiss-Prot: APC4_HUMAN, Q9UJX5Pathway: Protein modification; protein ubiquitination
ANAPC4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANAPC4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/105 Interacting proteins for ANAPC4 (Q9UJX52, 3 ENSP000003187754) via UniProtKB, MINT, STRING, and/or I2D (see all 105) About this table
Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table
ANAPC4 for ontologies About GeneDecksing
|
Drugs & Compounds for ANAPC4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ANAPC4 Search CenterWatch for drugs/clinical trials and news about ANAPC4 / APC4 
|
Transcripts for ANAPC4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ANAPC4 gene: NM_013367.2 Unigene Cluster for ANAPC4: Anaphase promoting complex subunit 4 Hs.152173 [show with all ESTs]Unigene Representative Sequence: AL35393211 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000315368(uc003gro.3 uc003grp.3) ENST00000510092(uc010iet.1 uc010ieu.1) ENST00000505080 ENST00000505991 ENST00000507809 ENST00000507925 ENST00000503805 ENST00000505842 ENST00000504256 ENST00000515848(uc003grq.3) ENST00000506973
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ANAPC4 (NM_013367) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANAPC4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC4  |
Additional cDNA sequence: AF191338.1 AK001881.1 AK023562.1 AK023597.1 AK292336.1 AL353932.1 AY429517.1 AY429518.1 BC059383.1 11 DOTS entries: DT.420654 DT.95368421 DT.40191933 DT.87077450 DT.97841353 DT.86851252 DT.102836230 DT.121234270 DT.91705239 DT.99972970 DT.121234264 24/140 AceView cDNA sequences (see all 140): Z38516 AW583671 AA384939 BC059383 BQ632338 AI200120 N63100 BP337824 BM683668 W73648 AI955406 CA975921 NM_013367 CA312572 AW513226 AW470099 AA428784 AW583446 BM479644 BQ011691 AI189513 AI979163 BX956361 Z42287 GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ANAPC4 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29a | · | 29b | · | 29c | |
| SP1: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ANAPC4
|
Expression for ANAPC4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANAPC4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGAGAGTATT
 About this image See ANAPC4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ANAPC4
SOURCE GeneReport for Unigene cluster: Hs.152173 SABiosciences Expression via Pathway-Focused PCR Array including ANAPC4:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANAPC4 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANAPC4 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANAPC4 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANAPC4 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC4 |
Orthologs for ANAPC4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ANAPC4 gene from 8/23 species (see all 23) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Anapc41 , 5 |
anaphase promoting complex subunit 41, 5 |
87.77(n)1 93.56(a)1 |
  |
5 (28.81 cM)5 522061 NM_024213.21 NP_077175.11 528340155 |
chicken (Gallus gallus) |
Aves |
ANAPC41 |
anaphase promoting complex subunit 4 |
76.61(n) 75.98(a) |
  |
422805 XM_001231776.2 XP_001231777.1 |
lizard (Anolis carolinensis) |
Reptilia |
ANAPC46 |
-- |
73(a) |
1 ↔ 1 |
GL343348.1(198374-227849) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
Str.37902 |
Transcribed sequence with weak similarity to protein more |
78.87(n) |
  |
BX714840.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufa95b032 |
Transcribed sequence with weak similarity to protein more |
74.13(n) |
  |
AL916167.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
APC41 |
Anaphase Promoting Complex 4 |
40.37(n) 26.34(a) |
  |
31835 NM_132294.3 NP_572522.2 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT4G215301 |
anaphase-promoting complex subunit 4 |
42.58(n) 26.01(a) |
  |
828238 NM_118273.7 NP_193884.6 |
rice (Oryza sativa) |
Liliopsida |
Os02g07859001 |
hypothetical protein |
41.72(n) 28.68(a) |
  |
4330947 NM_001054866.2 NP_001048331.2 |
ENSEMBL Gene Tree for ANAPC4 (if available) TreeFam Gene Tree for ANAPC4 (if available)  |
Paralogs for ANAPC4 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for ANAPC4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 4 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ANAPC4 (25378835 - 25420120 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ANAPC4: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANAPC4 |
|
Disorders
/ Diseases for ANAPC4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANAPC4 for disorders About GeneDecksing
OMIM gene information: 606947
OMIM disorders: --
2 diseases for ANAPC4: About MalaCardscytomegalovirus infection neuronitis Export disorders for ANAPC4 gene to outside databases
|
Publications for ANAPC4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANAPC4 gene, integrated from 9 sources (see all 52): (articles sorted by number of sources associating them with ANAPC4) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of a cullin homology region in a subunit of the anaphase-promoting complex. (PubMed id 9469815)1, 2, 9 Yu H.... Kirschner M.W. (1998)
- Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. (PubMed id 18485873)1, 2 Jin L....Rape M. (2008)
- Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PubMed id 16364912)1, 2 Dube P.... Stark H. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mitotic regulation of the human anaphase-promoting complex by phosphorylation. (PubMed id 14657031)1, 2 Kraft C....Peters J.-M. (2003)
- Two subgroups of HLA Bw44 defined by cell-mediated lympholysis that differ in Bw44 expression on platelets and in patterns of genetic linkage disequilibrium. (PubMed id 6180011)1, 3 Tekolf W.A....Shaw S. (1982)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for ANAPC4 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ANAPC4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANAPC4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANAPC4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ANAPC4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANAPC4 gene: Search GeneIP for patents involving ANAPC4
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for ANAPC4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANAPC4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANAPC4 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ANAPC4 | | OriGene 3'-UTR Clone for ANAPC4 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC4 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ANAPC4 | | OriGene Custom Protein Services for ANAPC4 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANAPC4 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANAPC4 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANAPC4 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANAPC4 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANAPC4 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANAPC4 |
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| | | Search Tocris compounds for ANAPC4 |
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 | | ANAPC4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC4 |
|  |  |  |  | | | ThermoFisher Antibodies for ANAPC4 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC4 |
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