Aliases for ANAPC2 Gene
Aliases for ANAPC2 Gene
External Ids for ANAPC2 Gene
- HGNC: 19989
- Entrez Gene: 29882
- Ensembl: ENSG00000176248
- OMIM: 606946
- UniProtKB: Q9UJX6
Previous GeneCards Identifiers for ANAPC2 Gene
- GC09M131759
- GC09M133510
- GC09M135426
- GC09M137345
- GC09M139189
- GC09M140069
- GC09M109530
Summaries for ANAPC2 Gene
-
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANAPC2 Gene
ANAPC2 (Anaphase Promoting Complex Subunit 2) is a Protein Coding gene. Among its related pathways are G-protein signaling G-Protein alpha-i signaling cascades and APC-Cdc20 mediated degradation of Nek2A. GO annotations related to this gene include ubiquitin protein ligase binding.
UniProtKB/Swiss-Prot for ANAPC2 Gene
-
Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANAPC2 Gene
Genomics for ANAPC2 Gene
Regulatory Elements for ANAPC2 Gene
Enhancers for ANAPC2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ANAPC2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ANAPC2 gene promoter:
Regulatory Element Products
Genomic Location for ANAPC2 Gene
- Chromosome:
- 9
- Start:
- 137,174,784 bp from pter
- End:
- 137,188,605 bp from pter
- Size:
- 13,822 bases
- Orientation:
- Minus strand
Genomic View for ANAPC2 Gene
Genes around ANAPC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.3 by Ensembl
- 9q34.3 by Entrez Gene
- 9q34.3 by HGNC
ANAPC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANAPC2 Gene
Proteins for ANAPC2 Gene
-
Protein details for ANAPC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJX6-ANC2_HUMAN
- Recommended name:
- Anaphase-promoting complex subunit 2
- Protein Accession:
- Q9UJX6
- Q5VSG1
- Q96DG5
- Q96GG4
- Q9P2E1
Protein attributes for ANAPC2 Gene
- Size:
- 822 amino acids
- Molecular mass:
- 93828 Da
- Quaternary structure:
-
- Interacts with NEUROD2 (By similarity). The mammalian APC/C is composed of 14 distinct subunits that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa. Interacts through the cullin domain with ANAPC11 and with UBCH10.
- SequenceCaution:
-
- Sequence=AAH09487.2; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for ANAPC2 Gene
Protein Expression for ANAPC2 Gene
Post-translational modifications for ANAPC2 Gene
Other Protein References for ANAPC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for ANAPC2 (APC2)
- Novus Biologicals Antibodies for ANAPC2
-
Abcam antibodies for ANAPC2
- Invitrogen Antibodies for ANAPC2
- antibodies-online Antibodies for ANAPC2: See all 55
- GeneTex ANAPC2 antibody for ANAPC2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ANAPC2
Protein Products
-
OriGene Purified Proteins for ANAPC2
- Search Origene for MassSpec and Protein Over-expression Lysates for ANAPC2
- Origene Custom Protein Services for ANAPC2
- antibodies-online Proteins for ANAPC2: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ANAPC2
-
Abcam proteins for ANAPC2
Assay Products
- antibodies-online Kits for ANAPC2: See all 10
No data available for DME Specific Peptides for ANAPC2 Gene
Domains & Families for ANAPC2 Gene
Gene Families for ANAPC2 Gene
Protein Domains for ANAPC2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ANAPC2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UJX6- Family:
-
- Belongs to the cullin family.
Function for ANAPC2 Gene
Molecular function for ANAPC2 Gene
- UniProtKB/Swiss-Prot Function:
- Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0031625 | ubiquitin protein ligase binding | IBA | -- |
| GO:0061630 | contributes_to ubiquitin protein ligase activity | IBA | -- |
Phenotypes for ANAPC2 Gene
- MGI mutant phenotypes for ANAPC2:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ANAPC2:
-
- Decreased viability
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Dynamic nuclei (hole, folded or small irregular)
- Effect on mitosis
- Decreased shRNA abundance (Z-score < -2)
- Decreased HIV-LTR-beta-galactosidase protein expression
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance
- Increased cell number in S
- Increased cell death HMECs cells
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Decreased viability of wild-type and TP53 knockout cells
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
- Decreased HIV-1 infection
Animal Models for ANAPC2 Gene
- MGI Knock Outs for ANAPC2:
-
- Anapc2 tm2Kna
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANAPC2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ANAPC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANAPC2 gene
- Search ViGene Biosciences for ANAPC2
CRISPR Products
-
OriGene CRISPR knockouts for ANAPC2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANAPC2
- GenScript: Design CRISPR guide RNA sequences for ANAPC2
miRNA for ANAPC2 Gene
- miRTarBase miRNAs that target ANAPC2
-
- hsa-mir-505-5p (MIRT491478)
- hsa-mir-3194-5p (MIRT491479)
- hsa-mir-4679 (MIRT491480)
- hsa-mir-4722-5p (MIRT491481)
- hsa-mir-4677-3p (MIRT491482)
- hsa-mir-6874-3p (MIRT491483)
- hsa-mir-6858-3p (MIRT491484)
- hsa-mir-148b-5p (MIRT491485)
- hsa-mir-148a-5p (MIRT491486)
- hsa-mir-6785-3p (MIRT711928)
- hsa-mir-3648 (MIRT711929)
- hsa-mir-4632-3p (MIRT711930)
- hsa-mir-4290 (MIRT711931)
- hsa-mir-4758-3p (MIRT711932)
- hsa-mir-361-3p (MIRT711933)
- hsa-mir-6849-3p (MIRT711934)
miRNA Products
- Search ViGene Biosciences for ANAPC2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ANAPC2
- Browse OriGene Inhibitory RNA Products For ANAPC2
-
ViGene Biosciences ready-to-package AAV shRNAs for ANAPC2 gene
Clone Products
-
OriGene ORF clones in human for ANAPC2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ANAPC2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ANAPC2
- VectorBuilder custom plasmid, inducible vectors for ANAPC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANAPC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ANAPC2
-
ViGene Biosciences adenoviral particle packaged cDNA for ANAPC2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ANAPC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANAPC2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ANAPC2 Gene
Localization for ANAPC2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005680 | anaphase-promoting complex | IDA | 16364912 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANAPC2 Gene
Pathways & Interactions for ANAPC2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 2 | APC-Cdc20 mediated degradation of Nek2A | ||
| 3 | Class I MHC mediated antigen processing and presentation | ||
| 4 | Cell Cycle, Mitotic |
.83
|
.60
|
| 5 | Cellular Senescence | ||
Pathways by source for ANAPC2 Gene
1 Sino Biological pathway for ANAPC2 Gene
1 Cell Signaling Technology pathway for ANAPC2 Gene
5 KEGG pathways for ANAPC2 Gene
7 GeneGo (Thomson Reuters) pathways for ANAPC2 Gene
6 Qiagen pathways for ANAPC2 Gene
UniProtKB/Swiss-Prot Q9UJX6-ANC2_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for ANAPC2 Gene
Selected Interacting proteins:
ENSP00000314004
Q9UJX6-ANC2_HUMAN
for ANAPC2 Gene via
STRING
MINT
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007067 | mitotic nuclear division | IEA | -- |
| GO:0007399 | nervous system development | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
Transcripts for ANAPC2 Gene
mRNA/cDNA for ANAPC2 Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (212) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ANAPC2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ANAPC2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANAPC2
- GenScript: Design CRISPR guide RNA sequences for ANAPC2
miRNA Products
- Search ViGene Biosciences for ANAPC2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ANAPC2
- Browse OriGene Inhibitory RNA Products For ANAPC2
-
ViGene Biosciences ready-to-package AAV shRNAs for ANAPC2 gene
Clone Products
-
OriGene ORF clones in human for ANAPC2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ANAPC2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ANAPC2
- VectorBuilder custom plasmid, inducible vectors for ANAPC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANAPC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | ^ | 14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for ANAPC2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Bone (50.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ANAPC2 Gene
NURSA nuclear receptor signaling pathways regulating expression of ANAPC2 Gene:
ANAPC2SOURCE GeneReport for Unigene cluster for ANAPC2 Gene:
Hs.533262Evidence on tissue expression from TISSUES for ANAPC2 Gene
- Nervous system(4.4)
- Liver(4.3)
- Stomach(2.1)
Primer Products
-
OriGene qPCR primer pairs for ANAPC2
-
OriGene qPCR primer pairs and template standards for ANAPC2
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANAPC2 Gene
Orthologs for ANAPC2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ANAPC2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | ANAPC2 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Anapc2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Anapc2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ANAPC2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ANAPC2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ANAPC2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ANAPC2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | anapc2 34 |
|
||
| Str.15442 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | anapc2 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | mr 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005048 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | apc-2 35 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | APC2 35 37 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | APC2 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0484800 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for ANAPC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ANAPC2 Gene
No data available for Paralogs for ANAPC2 Gene
Variants for ANAPC2 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000143800 | -- | 137,182,079(+) | AAGGC(C/T)GGCCT | intron-variant | |
| rs1000219495 | -- | 137,185,489(+) | CGCCG(C/T)GGGGC | intron-variant | |
| rs1000250402 | -- | 137,185,697(+) | CAGGA(C/T)GGGGG | intron-variant | |
| rs1000254588 | -- | 137,175,320(+) | GTTGT(C/T)CCGGT | nc-transcript-variant, reference, missense | |
| rs1000352600 | -- | 137,183,401(+) | GTTCA(C/T)AGGTC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv13009n54 | CNV | loss | 21841781 |
| esv2422220 | CNV | deletion | 17116639 |
| esv2761561 | CNV | gain | 21179565 |
| nsv1161918 | CNV | duplication | 26073780 |
| nsv524322 | CNV | loss | 19592680 |
| nsv616007 | CNV | loss | 21841781 |
| nsv951207 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
6.48% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.78;
33.56% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ANAPC2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ANAPC2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANAPC2 Gene
Disorders for ANAPC2 Gene
Relevant External Links for ANAPC2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ANAPC2
No disorders were found for ANAPC2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANAPC2 Gene
Publications for ANAPC2 Gene
- APC2 cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. (PMID: 11739784) Tang Z. … Yu H. (Mol. Biol. Cell 2001) 2 3 4 64
- Identification of a cullin homology region in a subunit of the anaphase-promoting complex. (PMID: 9469815) Yu H. … Kirschner M.W. (Science 1998) 3 4 22 64
- Molecular architecture and mechanism of the anaphase-promoting complex. (PMID: 25043029) Chang L. … Barford D. (Nature 2014) 3 4 64
- Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex. (PMID: 18485873) Jin L. … Rape M. (Cell 2008) 3 4 64
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3 4 64
Products for ANAPC2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ANAPC2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ANAPC2
- Search Origene for MassSpec and Protein Over-expression Lysates for ANAPC2
- Origene Custom Protein Services for ANAPC2
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ANAPC2
- Browse OriGene Inhibitory RNA Products For ANAPC2
- OriGene qPCR primer pairs and template standards for ANAPC2
- OriGene qPCR primer pairs for ANAPC2
- OriGene CRISPR knockouts for ANAPC2
- OriGene ORF clones in human for ANAPC2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ANAPC2
- GenScript: Next-day shipping cDNA ORF clone for ANAPC2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ANAPC2
- GenScript Custom Assay Services for ANAPC2
- GenScript Custom overexpressing Cell Line Services for ANAPC2
- GenScript: Design CRISPR guide RNA sequences for ANAPC2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ANAPC2
- Cell Signaling Technology (CST) Antibodies for ANAPC2 (APC2)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for ANAPC2
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ANAPC2
- Novus Biologicals proteins and lysates for ANAPC2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for ANAPC2
- Abcam proteins for ANAPC2
- Search for Assays for ANAPC2 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Addgene plasmids for ANAPC2
- antibodies-online Antibodies for ANAPC2: See all 55
- antibodies-online Kits for ANAPC2: See all 10
- antibodies-online Proteins for ANAPC2: See all 5
- Search antibodies-online for peptides
- GeneTex ANAPC2 antibody for ANAPC2
- Search GeneTex for Proteins for ANAPC2
- ViGene Biosciences adenoviral particle packaged cDNA for ANAPC2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ANAPC2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ANAPC2 gene
- Search ViGene Biosciences for ANAPC2
- Santa Cruz Biotechnology (SCBT) Antibodies for ANAPC2
- Search Santa Cruz Biotechnology (SCBT) for ANAPC2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ANAPC2
- Horizon Cell Lines for ANAPC2
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANAPC2
- VectorBuilder custom plasmid, inducible vectors for ANAPC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANAPC2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ANAPC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer