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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANAPC15 Gene

protein-coding   GIFtS: 37
GCID: GC11M071817

Anaphase Promoting Complex Subunit 15

(Previous name: chromosome 11 open reading frame 51)
(Previous symbol: C11orf51)
  Search for ANAPC15
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Anaphase Promoting Complex Subunit 151 2
C11orf511 2 3
APC152 3
Chromosome 11 Open Reading Frame 511
Anaphase-Promoting Complex Subunit 152

External Ids:    HGNC: 245311   Entrez Gene: 259062   Ensembl: ENSG000001102007   OMIM: 6147175   UniProtKB: P600063   

Export aliases for ANAPC15 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ANAPC15 Gene: 
ANAPC15 (anaphase promoting complex subunit 15) is a protein-coding gene.

UniProtKB/Swiss-Prot: APC15_HUMAN, P60006
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin
ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role
in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself,
but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the
spindle assembly checkpoint. Also required for degradation of CDC20




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ANAPC15
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ANAPC15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANAPC15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.4   Ensembl cytogenetic band:  11q13.4   HGNC cytogenetic band: 11q13.4

ANAPC15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANAPC15 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M071817:  view genomic region     (about GC identifiers)

Start:
71,817,424 bp from pter      End:
71,823,826 bp from pter
Size:
6,403 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: APC15_HUMAN, P60006 (See protein sequence)
Recommended Name: Anaphase-promoting complex subunit 15  
Size: 121 amino acids; 14281 Da
Subunit: The APC/C is composed of at least 12 subunits
Sequence caution: Sequence=EAW74842.1; Type=Erroneous gene model prediction;
Secondary accessions: G3V1Q3 Q9CXK2 Q9Y269

Explore the universe of human proteins at neXtProt for ANAPC15: NX_P60006

Explore proteomics data for ANAPC15 at MOPED 

ANAPC15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

ANAPC15 Protein Expression

REFSEQ proteins (11 alternative transcripts): 
NP_001265414.1  NP_001265415.1  NP_001265416.1  NP_001265417.1  NP_001265418.1  NP_001265419.1  NP_001265420.1  NP_001265421.1  
NP_001265422.1  NP_001265423.1  NP_054761.1  

ENSEMBL proteins: 
 ENSP00000441774   ENSP00000437360   ENSP00000445212   ENSP00000439403   ENSP00000443645  
 ENSP00000227618   ENSP00000443911   ENSP00000446412   ENSP00000446383   ENSP00000440002  
 ENSP00000443383   ENSP00000440983   ENSP00000437683   ENSP00000389730   ENSP00000439362  
 ENSP00000440380  

Human Recombinant Protein Products for ANAPC15: 
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Novus Biologicals ANAPC15 Lysate
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Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular IDA--
GO:0005680anaphase-promoting complex IDA--

ANAPC15 for ontologies           About GeneDecksing



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Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
ANAPC: Anaphase promoting complex subunits

1 InterPro protein domain:
 IPR026182 ANAPC15

Graphical View of Domain Structure for InterPro Entry P60006

ProtoNet protein and cluster: P60006

UniProtKB/Swiss-Prot: APC15_HUMAN, P60006
Similarity: Belongs to the APC15 family


ANAPC15 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: APC15_HUMAN, P60006
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin
ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role
in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself,
but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the
spindle assembly checkpoint. Also required for degradation of CDC20

Phenotypes:
     3 GenomeRNAi human phenotypes for ANAPC15:

 Cell division defect  Increased G2M DNA content  Increased number of mitotic ce 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for ANAPC15 
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miRNA
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Inhib. RNA
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Gene Editing
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In Situ Assay
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section




Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANAPC15

STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

5/22 Interacting proteins for ANAPC15 (ENSP000002276184) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
InteractantInteraction Details
GeneCardExternal ID(s)
ANAPC16ENSP000002993814STRING: ENSP00000299381
CDC16ENSP000003485544STRING: ENSP00000348554
CDC23ENSP000003783504STRING: ENSP00000378350
ANAPC1ENSP000003391094STRING: ENSP00000339109
ANAPC10ENSP000003100714STRING: ENSP00000310071
About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007067mitosis IEA--
GO:0051301cell division IEA--
GO:0090266regulation of mitotic cell cycle spindle assembly checkpoint IMP--

ANAPC15 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ANAPC15 (APC15)

Search CenterWatch for drugs/clinical trials and news about ANAPC15 / APC15

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ANAPC15 gene (11 alternative transcripts): 
NM_001278485.1  NM_001278486.1  NM_001278487.1  NM_001278488.1  NM_001278489.1  NM_001278490.1  NM_001278491.1  NM_001278492.1  
NM_001278493.1  NM_001278494.1  NM_014042.2  

Unigene Cluster for ANAPC15:

Anaphase promoting complex subunit 15
Hs.38044  [show with all ESTs]
Unigene Representative Sequence: AK311146
17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000502597(uc009ytc.1) ENST00000543050 ENST00000538117 ENST00000543587(uc001orv.3)
ENST00000543015 ENST00000545680 ENST00000227618(uc001orw.3) ENST00000542531
ENST00000535234 ENST00000545944 ENST00000538393 ENST00000535503 ENST00000538919
ENST00000537644 ENST00000438939 ENST00000545333 ENST00000539395
miRNA
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SwitchGear 3'UTR luciferase reporter plasmidANAPC15 3' UTR sequence
Inhib. RNA
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                     Customized lentivirus expression plasmids for stable overexpression of ANAPC15 
Primer
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANAPC15

Additional mRNA sequence: 

AF077206.1 AK222622.1 AK311146.1 AL080071.1 BC005156.2 BC005393.1 

12 DOTS entries:

DT.91640431  DT.102824953  DT.120712088  DT.85105330  DT.120711959  DT.97843177  DT.120711949  DT.85105329 
DT.95233089  DT.120712098  DT.121281162  DT.92473190 

24/593 AceView cDNA sequences (see all 593):

CR619743 BM744923 BU952060 BU789993 AA918212 BU784910 AI676075 BM987519 
CD674529 CD364368 AI149055 AI151518 CB853459 AI220889 BM740885 CK823821 
Z24996 BU951805 AI375781 AW299903 BX361114 BQ689970 AA953741 BQ420503 

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ANAPC15 (see all 6)    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9
SP1:              -           -                       -                                       
SP2:              -                                                                           
SP3:              -                                   -                                       
SP4:              -                                   -                                       
SP5:                                                  -     -     -     -     -               


ECgene alternative splicing isoforms for ANAPC15

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ANAPC15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ANAPC15 Expression
About this image


See ANAPC15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANAPC15

SOURCE GeneReport for Unigene cluster: Hs.38044
    SABiosciences Custom PCR Arrays for ANAPC15
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC15

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ANAPC15 gene from 5/11 species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Anapc151 , 5 RIKEN cDNA 3200002M19 gene5
anaphase prompoting complex C subunit 151
94.21(n)1
100(a)1
  7 (54.68 cM)5
754301  NM_027532.31  NP_081808.21 
 1018813255 
chicken
(Gallus gallus)
Aves LOC1008574051 uncharacterized LOC100857405 83.75(n)
94.21(a)
  100857405  XM_003643434.1  XP_003643482.1 
lizard
(Anolis carolinensis)
Reptilia ANAPC156
anaphase promoting complex subunit 15
73(a)
1 ↔ 1
GL343792.1(7520-21283)
African clawed frog
(Xenopus laevis)
Amphibia Xl.64272 Xenopus laevis transcribed sequence with moderate similarity more 80.17(n)    48058459 
zebrafish
(Danio rerio)
Actinopterygii Dr.132922 Transcribed sequence with moderate similarity to protein more 83.5(n)    BI672822.1 


ENSEMBL Gene Tree for ANAPC15 (if available)
TreeFam Gene Tree for ANAPC15 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for ANAPC15 gene

ANAPC15 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for ANAPC15
PGOHUM00000241182


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/75 SNPs in ANAPC15 are shown (see all 75)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs37509081,2
C,F,H--71822401(-) ATCCCT/CAAATC 1 -- int121Minor allele frequency- C:0.17NS EA NA WA CSA 2347
rs1468652241,2
C--71822475(+) CCTGG-/CTCCAC 1 -- ut510--------
rs37509071,2
C,A--71822560(-) TTGTTA/GTTATC 1 -- int14Minor allele frequency- G:0.09CSA WA NA EA 361
rs50242411,2
H--71822682(+) TCCAGA/GATGCA 1 -- int14Minor allele frequency- G:0.00NS EA 408
rs1881513921,2
--71822809(+) CCCACA/CCAGTG 1 -- int10--------
rs562490891,2
C,F--71822845(+) TCTCAT/CGAATC 1 -- int13Minor allele frequency- C:0.07WA CSA 122
rs1178189251,2
C,F--71822952(+) GAAGAT/CTGAAT 1 -- int11Minor allele frequency- C:0.04NA 120
rs1808024451,2
--71822953(+) AAGATG/TGAATG 1 -- int10--------
rs1842730481,2
--71822960(+) AATGGA/GTGAAC 1 -- int10--------
rs1886575041,2
--71822989(+) ATCAGC/TTTTGA 1 -- int10--------

HapMap Linkage Disequilibrium report for ANAPC15 (71817424 - 71823826 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ANAPC15: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing ANAPC15
DNA2.0 Custom Variant and Variant Library Synthesis for ANAPC15

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ANAPC15 for disorders           About MalaCards
OMIM gene information: 614717    OMIM disorders: --


ANAPC15 for disorders           About GeneDecksing


Export disorders for ANAPC15 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ANAPC15 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with ANAPC15)
    Utopia: connect your pdf to the dynamic
world of online information

  1. APC15 drives the turnover of MCC-CDC20 to make the sp indle assembly checkpoint responsive to kinetochore attachment. (PubMed id 21926987)1, 2, 3 Mansfeld J....Pines J. (2011)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
  4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
  5. Transcriptional intermediary factor 1g binds to the an aphase-promoting complex/cyclosome and promotes mitosis. (PubMed id 23160376)1 Sedgwick G.G....Turnell A.S. (2013)
  6. APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. (PubMed id 23007861)1 Uzunova K....Peters J.M. (2012)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  8. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
  9. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 25906 HGNC: 24531 AceView: DKFZP564M082andFLJ20625 Ensembl:ENSG00000110200 euGenes: HUgn25906
ECgene: ANAPC15 H-InvDB: ANAPC15

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for ANAPC15 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ANAPC15 gene:
Search GeneIP for patents involving ANAPC15

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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