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ANAPC13 Gene

protein-coding   GIFtS: 54
GCID: GC03M134196

Anaphase Promoting Complex Subunit 13

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Anaphase Promoting Complex Subunit 131 2
APC132 3 5
Cyclosome Subunit 132 3
SWM12 5
Anaphase-Promoting Complex Subunit 132

External Ids:    HGNC: 245401   Entrez Gene: 258472   Ensembl: ENSG000001290557   OMIM: 6144845   UniProtKB: Q9BS183   

Export aliases for ANAPC13 gene to outside databases

Previous GC identifers: GC03M135518 GC03M135679 GC03M131574


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANAPC13 Gene:
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls
cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded
protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the
anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the
biological validity of some of the splice variants has not been determined. (provided by RefSeq, Nov 2008)

GeneCards Summary for ANAPC13 Gene:
ANAPC13 (anaphase promoting complex subunit 13) is a protein-coding gene. Diseases associated with ANAPC13 include crohn's disease, and hepatocellular carcinoma.

UniProtKB/Swiss-Prot: APC13_HUMAN, Q9BS18
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin
ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by
mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of
'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked
polyubiquitin chains




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANAPC13 gene promoter:
         NF-1   SREBP-1a   SREBP-1c   SREBP-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANAPC13 promoter sequence
   Search Chromatin IP Primers for ANAPC13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANAPC13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.2   Ensembl cytogenetic band:  3q22.2   HGNC cytogenetic band: 3q22.1

ANAPC13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANAPC13 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M134196:  view genomic region     (about GC identifiers)

Start:
134,196,546 bp from pter      End:
134,205,558 bp from pter
Size:
9,013 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: APC13_HUMAN, Q9BS18 (See protein sequence)
Recommended Name: Anaphase-promoting complex subunit 13  
Size: 74 amino acids; 8521 Da
Subunit: The APC/C is composed of at least 12 subunits
Sequence caution: Sequence=CAB43251.1; Type=Erroneous translation; Note=Wrong choice of frame;
Secondary accessions: Q9Y3V0

Explore the universe of human proteins at neXtProt for ANAPC13: NX_Q9BS18

Explore proteomics data for ANAPC13 at MOPED


See ANAPC13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001229303.1  NP_001229304.1  NP_056206.1  

ENSEMBL proteins: 
 ENSP00000421842   ENSP00000346987   ENSP00000427327   ENSP00000421760  
Reactome Protein details: Q9BS18

ANAPC13 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ANAPC: Anaphase promoting complex subunits

1 InterPro protein domain:
 IPR008401 Apc13p

Graphical View of Domain Structure for InterPro Entry Q9BS18

ProtoNet protein and cluster: Q9BS18

UniProtKB/Swiss-Prot: APC13_HUMAN, Q9BS18
Similarity: Belongs to the APC13 family


ANAPC13 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: APC13_HUMAN, Q9BS18
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin
ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by
mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of
'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked
polyubiquitin chains

Animal Models:

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miRNA
Products:
    
miRTarBase miRNAs that target ANAPC13:
hsa-mir-26b-5p (MIRT029001), hsa-mir-324-5p (MIRT043053), hsa-mir-16-5p (MIRT031495)

Block miRNA regulation of human, mouse, rat ANAPC13 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate ANAPC13:
hsa-miR-33a*
SwitchGear 3'UTR luciferase reporter plasmidANAPC13 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for ANAPC13
Predesigned siRNA for gene silencing in human, mouse, rat ANAPC13

Gene Editing
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GenScript: all cDNA clones in your preferred vector: ANAPC13 (NM_015391)
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC13


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
APC13_HUMAN, Q9BS18: Nucleus (Probable)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
extracellular2
cytosol1
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005680anaphase-promoting complex IDA16364912

ANAPC13 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ANAPC13 About   (see all 11)                                                                                              See pathways by source

SuperPathContained pathways About
1Class I MHC mediated antigen processing and presentation
Class I MHC mediated antigen processing and presentation0.84
Adaptive Immune System0.41
Antigen processing- Ubiquitination and Proteasome degradation0.84
Ubiquitin mediated proteolysis0.35
2Cell cycle Regulation of G1 S transition part 1
Cell cycle Regulation of G1 S transition part 1 0.39
Cell cycle Role of SCF complex in cell cycle regulation0.39
3Oocyte meiosis
Oocyte meiosis0.35
Progesterone-mediated oocyte maturation0.35
4Cell cycle
Cell cycle0.59
5G protein signaling G Protein alpha i signaling cascades
G protein signaling G Protein alpha s signaling cascades0.44

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


Selected GeneGo (Thomson Reuters) Pathways for ANAPC13 (see all 7)
    Cell cycle Role of APC in cell cycle regulation
G-protein signaling G-Protein alpha-s signaling cascades
Signal transduction PKA signaling
Cell cycle Regulation of G1/S transition (part 1)
Cell cycle Spindle assembly and chromosome separation

1 Reactome Pathway for ANAPC13
    Antigen processing: Ubiquitination & Proteasome degradation


4 Kegg Pathways  (Kegg details for ANAPC13):
    Cell cycle
Oocyte meiosis
Ubiquitin mediated proteolysis
Progesterone-mediated oocyte maturation

UniProtKB/Swiss-Prot: APC13_HUMAN, Q9BS18
Pathway: Protein modification; protein ubiquitination


ANAPC13 for pathways           About GeneDecksing

    Pathway & Disease-focused RT2 Profiler PCR Array including ANAPC13: 

          Ubiquitin Ligases in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for ANAPC13

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for ANAPC13 (Q9BS183 ENSP000003469874) via UniProtKB, MINT, STRING, and/or I2D (see all 45)
InteractantInteraction Details
GeneCardExternal ID(s)
ANAPC1Q9H1A43, ENSP000003391094I2D: score=1 STRING: ENSP00000339109
ANAPC16Q96DE53, ENSP000002993814I2D: score=1 STRING: ENSP00000299381
ANAPC5Q9UJX43, ENSP000002618194I2D: score=1 STRING: ENSP00000261819
CDC26Q8NHZ83, ENSP000003633224I2D: score=1 STRING: ENSP00000363322
CCNB1P146353, ENSP000002564424I2D: score=1 STRING: ENSP00000256442
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007067mitosis IEA--
GO:0070979protein K11-linked ubiquitination IDA18485873

ANAPC13 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ANAPC13 (APC13)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for ANAPC13 gene (3 alternative transcripts): 
NM_001242374.1  NM_001242375.1  NM_015391.3  

Unigene Cluster for ANAPC13:

Anaphase promoting complex subunit 13
Hs.106909  [show with all ESTs]
Unigene Representative Sequence: NM_001242374
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000510994(uc003eqj.3 uc003eqi.3 uc003eqk.4) ENST00000354910
ENST00000514612 ENST00000511751 ENST00000508755 ENST00000503439
miRNA
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Block miRNA regulation of human, mouse, rat ANAPC13 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate ANAPC13:
hsa-miR-33a*
SwitchGear 3'UTR luciferase reporter plasmidANAPC13 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ANAPC13
Predesigned siRNA for gene silencing in human, mouse, rat ANAPC13
Clone
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OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ANAPC13 (NM_015391)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANAPC13
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC13
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ANAPC13
OriGene qSTAR qPCR primer pairs in human, mouse for ANAPC13
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ANAPC13
  QuantiTect SYBR Green Assays in human, mouse, rat ANAPC13
  QuantiFast Probe-based Assays in human, mouse, rat ANAPC13

Additional mRNA sequence: 

AF086169.1 AK001285.1 AK026550.1 AK290761.1 AL050051.1 BC005398.1 BX537696.1 

22 DOTS entries:

DT.100825349  DT.97821810  DT.446464  DT.95112446  DT.100825351  DT.120876684  DT.100737585  DT.92457942 
DT.95242637  DT.97859064  DT.95242638  DT.312261  DT.100825350  DT.120876632  DT.92006895  DT.92410708 
DT.95242633  DT.100825346  DT.120876589  DT.92457943  DT.92457949  DT.97810404 

Selected AceView cDNA sequences (see all 494):

BE380147 AA134530 AI563951 AA953886 BE906784 BM722658 BM702334 AI298573 
AI922969 AA846432 BF001200 AI074404 AA377137 AA772419 BM672055 BM807200 
CD677553 AA278481 BM842760 AI582806 CB217751 CB158901 BX281744 AW170260 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for ANAPC13 (see all 6)    About this scheme

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e
SP1:        -     -     -     -     -     -           -                                 
SP2:                          -     -     -           -                                 
SP3:                                -     -           -                                 
SP4:                                      -           -                                 
SP5:                                -     -                                             


ECgene alternative splicing isoforms for ANAPC13

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ANAPC13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTCTCTCCCC
ANAPC13 Expression
About this image

ANAPC13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ANAPC13 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.106909
    Pathway & Disease-focused RT2 Profiler PCR Array including ANAPC13: 
          Ubiquitin Ligases in human mouse rat

Primer
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QuantiFast Probe-based Assays in human, mouse, rat ANAPC13
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC13

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for ANAPC13 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Anapc131 , 5 anaphase promoting complex subunit 131, 5 86.94(n)1
95.95(a)1
  9 (54.64 cM)5
690101  NM_181394.31  NP_852059.11 
 1026262965 
chicken
(Gallus gallus)
Aves ANAPC131 anaphase promoting complex subunit 13 78.83(n)
97.3(a)
  769605  NM_001277482.1  NP_001264411.1 
African clawed frog
(Xenopus laevis)
Amphibia 480315382   -- 77.1(n)    48031538 
zebrafish
(Danio rerio)
Actinopterygii Dr.144802 Transcribed sequence with weak similarity to protein more 78.61(n)    BI672555.1 
fruit fly
(Drosophila melanogaster)
Insecta CG339816
--
40(a)
1 ↔ 1
2R(13661469-13669417)


ENSEMBL Gene Tree for ANAPC13 (if available)
TreeFam Gene Tree for ANAPC13 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ANAPC13 gene

ANAPC13 for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for ANAPC13
PGOHUM00000244160 PGOHUM00000247593


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ANAPC13 (see all 134)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1387729501,2
C--134196060(+) TTCTGA/GTTCAG 3 -- ds50010--------
rs1418373251,2
--134196171(+) GTGTCA/TCAGAG 3 -- ds50010--------
rs761252701,2
C,F--134196186(+) CATACC/TACAAG 3 -- ds50011Minor allele frequency- T:0.02WA 118
rs1929338621,2
--134196198(+) AAGCTA/GTAAAA 3 -- ds50010--------
rs1841037061,2
--134196210(+) CCTCAC/TTTAAC 3 -- ds50010--------
rs785967451,2
F--134196238(+) GTGGCG/ATTCTA 3 -- ds50012Minor allele frequency- A:0.11CSA WA 120
rs1887832481,2
--134196290(+) TTTTTC/TAATAT 3 -- ds50010--------
rs1461958031,2
--134196362(+) GTCTTC/TATTCT 3 -- ds50010--------
rs1808636011,2
--134196461(+) CATGTC/TTGTGA 3 -- ds50010--------
rs50161721,2
C,H--134196747(+) CTAAAT/AACTGA 3 -- ut312Minor allele frequency- A:0.00NS 208

HapMap Linkage Disequilibrium report for ANAPC13 (134196546 - 134205558 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for ANAPC13:    About this table    
Variant IDTypeSubtypePubMed ID
nsv829730CNV Loss17160897
dgv5259n71CNV Loss21882294
esv33705CNV Loss17666407
nsv877510CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ANAPC13
DNA2.0 Custom Variant and Variant Library Synthesis for ANAPC13

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 614484    OMIM disorders: --

2 diseases for ANAPC13:    About MalaCards
crohn's disease    hepatocellular carcinoma


ANAPC13 for disorders           About GeneDecksing

Genetic Association Database (GAD): ANAPC13
Human Genome Epidemiology (HuGE) Navigator: ANAPC13 (2 documents)

Export disorders for ANAPC13 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ANAPC13 gene, integrated from 10 sources (see all 17):
(articles sorted by number of sources associating them with ANAPC13)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase- promoting complex stabilizing the association of Cdc16 and Cdc27. (PubMed id 15060174)1, 2, 3 Schwickart M.... Zachariae W. (Mol. Cell. Biol. 2004)
  2. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
  3. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. (PubMed id 20846217)1, 4 Lee J.J....Hirschhorn J. (Ann. Hum. Genet. 2010)
  4. Mechanism of ubiquitin-chain formation by the human anaphase- promoting complex. (PubMed id 18485873)1, 2 Jin L.... Rape M. (Cell 2008)
  5. Genome-wide association analysis identifies 20 loci that influence adult height. (PubMed id 18391952)1, 4 Weedon M.N....Frayling T.M. (Nat. Genet. 2008)
  6. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PubMed id 16364912)1, 2 Dube P.... Stark H. (Mol. Cell 2005)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
  10. Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads. (PubMed id 21043528)1 Holzmann J....Mechtler K. (J. Proteome Res. 2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 25847 HGNC: 24540 AceView: ANAPC13 Ensembl:ENSG00000129055 euGenes: HUgn25847
ECgene: ANAPC13 Kegg: 25847 H-InvDB: ANAPC13

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ANAPC13 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ANAPC13 gene:
Search GeneIP for patents involving ANAPC13

GeneCards and IP:
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