ANAPC11 Gene
protein-coding GIFtS: 59
GCID: GC17P079849
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|
anaphase promoting complex subunit 11(Previous name: anaphase promoting complex subunit 11 (yeast APC11 homolog)...)
| |
Aliases for ANAPC11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Anaphase Promoting Complex Subunit 111 2 | | Hepatocellular Carcinoma-Associated RING Finger Protein2 3 | | APC111 2 3 | | HSPC2141 | | Apc11p1 2 | | MGC8821 | | Anaphase Promoting Complex Subunit 11 (Yeast APC11 Homolog)1 2 | | Anaphase-Promoting Complex Subunit 112 | | Cyclosome Subunit 112 3 | | APC11 Anaphase Promoting Complex Subunit 11 Homolog2 |
Export aliases for ANAPC11 gene to outside databasesPrevious GC identifers: GC17P079341 GC17P9I0152 GC17P080384 GC17P077442 GC17P075220 |
Summaries for ANAPC11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Mayrecruit the E2 ubiquitin-conjugating enzymes to the complex Gene Wiki entry for ANAPC11
|
Genomic Views for ANAPC11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010663.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ANAPC11 gene promoter: CUTL1 Other transcription factors
Search SABiosciences Chromatin IP Primers for ANAPC11
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANAPC11 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.3 Ensembl cytogenetic band: 17q25.3 HGNC cytogenetic band: 17q25.3ANAPC11 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P079849: view genomic region
(about GC identifiers)
Start:
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79,848,666 bp from pter |
End:
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79,858,867 bp from pter |
Size:
|
10,202 bases |
Orientation:
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plus strand |
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Proteins for ANAPC11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5 (See
protein sequence)Recommended Name: Anaphase-promoting complex subunit 11 Size: 84 amino acids; 9841 Da
Subunit: The APC/C is composed of at least 12 subunits. Interacts with the cullin domain of ANAPC2. Interacts withUBE2D2
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=AAF36134.1; Type=Frameshift; Positions=67;
Secondary accessions: A8MTT2 B7ZW64 Q502X9 Q9BW64 Q9P0R2Alternative splicing: 2 isoforms: Q9NYG5-1 Q9NYG5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ANAPC11: NX_Q9NYG5
Post-translational modifications:
Auto-ubiquitinated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NYG5 ANAPC11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001002244.1 NP_001002245.1 NP_001002246.1 NP_001002247.1 NP_001002248.1 NP_001002249.1 NP_057560.8 ENSEMBL proteins: ENSP00000458143 ENSP00000460678 ENSP00000463640 ENSP00000339695 ENSP00000464403 ENSP00000462691 ENSP00000461648 ENSP00000460064 ENSP00000458265 ENSP00000349957 ENSP00000462250 ENSP00000459200 ENSP00000464615 ENSP00000463567 ENSP00000463889 ENSP00000376181 ENSP00000464519 ENSP00000463598 ENSP00000463357 ENSP00000458515 ENSP00000462527 Reactome Protein details: Q9NYG5 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ANAPC11 for ontologies About GeneDecksing
ANAPC11 Antibody Products: Assay Products for ANAPC11: |
Protein
Domains / Families for ANAPC11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANAPC11 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NYG5ProtoNet protein and cluster: Q9NYG5 1 Blocks protein family: IPB001841 Zn-finger
UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5Domain: The RING-type zinc finger domain coordinates an additional third zinc ionSimilarity: Belongs to the RING-box familySimilarity: Contains 1 RING-type zinc finger |
Function for ANAPC11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Mayrecruit the E2 ubiquitin-conjugating enzymes to the complex
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 (see all 9) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): ANAPC11 (NM_001002244) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANAPC11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC11  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC11 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | contributes to ubiquitin-protein ligase activity |
IDA | 11739784 | | GO:0008270 | zinc ion binding |
IEA | -- |
ANAPC11 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for ANAPC11:
|
Pathways & Interactions for ANAPC11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/21 super-pathways (see all 21) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitinated Orc1 is degraded by the proteasome | | | 2 | APC-Cdc20 mediated degradation of Nek2A | | | 3 | M Phase | | | 4 | Antigen processing: Ubiquitination & Proteasome degradation | | | 5 | Cell cycle_Spindle assembly and chromosome separation | |
Pathway sources See GeneCards unified pathways Show all pathways
5/9 EMD Millipore Pathways for ANAPC11 (see all 9) 5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ANAPC11 (see all 6) 5/7 GeneGo (Thomson Reuters) Pathways for ANAPC11 (see all 7) 5/36
Reactome Pathways for ANAPC11 (see all 36)
4
Kegg Pathways (Kegg details for ANAPC11): UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5Pathway: Protein modification; protein ubiquitination
ANAPC11 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ANAPC11
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/107 Interacting proteins for ANAPC11 (Q9NYG53 ENSP000003499574) via UniProtKB, MINT, STRING, and/or I2D (see all 107) About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
ANAPC11 for ontologies About GeneDecksing
|
Drugs & Compounds for ANAPC11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ANAPC11 Search CenterWatch for drugs/clinical trials and news about ANAPC11 / APC11 
|
Transcripts for ANAPC11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ANAPC11 gene (7 alternative transcripts): NM_001002244.1 NM_001002245.1 NM_001002246.1 NM_001002247.1 NM_001002248.1 NM_001002249.1 NM_016476.10 Unigene Cluster for ANAPC11: Anaphase promoting complex subunit 11 Hs.534456 [show with all ESTs]Unigene Representative Sequence: BQ96127218/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000571570 ENST00000572639 ENST00000579978 ENST00000344877(uc002kbv.1 uc002kbw.1 uc002kbx.1 uc002kbz.1 uc002kca.1 uc002kcb.1 uc002kcc.1) ENST00000582222 ENST00000577425 ENST00000571024 ENST00000574924 ENST00000572851 ENST00000357385(uc002kby.1) ENST00000584314 ENST00000571874 ENST00000578550 ENST00000577747 ENST00000579133 ENST00000392376 ENST00000584197 ENST00000583839
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 (see all 9) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): ANAPC11 (NM_001002244) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANAPC11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC11  |
Additional cDNA sequence: AF151048.1 AF247565.1 AF247789.1 AK307214.1 AK308091.1 BC000607.1 BC066308.1 BC095454.1 BC104641.1 BC171892.1 BC171898.1 BC171899.1 BC171900.1 24 DOTS entries: DT.100826159 DT.100826158 DT.100800423 DT.100826161 DT.86847246 DT.97815021 DT.92437366 DT.95198886 DT.92437369 DT.95345705 DT.100826160 DT.95345698 DT.100038051 DT.120912355 DT.95196802 DT.113574 DT.120912329 DT.99942502 DT.99971063 DT.120912279 DT.92437359 DT.92437365 DT.95345732 DT.97859422 24/123 AceView cDNA sequences (see all 123): BF446070 BU957767 BM785773 AI523869 AI452979 AI085289 AI285920 AI809223 AW082296 AI343405 AI934760 BM782350 AI423863 BM854462 AI243940 AI299722 AI088790 BM784649 BU538782 BM766572 BM782652 AF086513 AI824093 BF512771 GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for ANAPC11 (see all 17) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ANAPC11
|
Expression for ANAPC11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANAPC11 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CTGGCGCCGA
About this image See ANAPC11 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ANAPC11
SOURCE GeneReport for Unigene cluster: Hs.534456 UniProtKB/Swiss-Prot: APC11_HUMAN, Q9NYG5Tissue specificity: Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, andliver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte SABiosciences Expression via Pathway-Focused PCR Arrays including ANAPC11:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANAPC11 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANAPC11 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANAPC11 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANAPC11 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC11 |
Orthologs for ANAPC11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ANAPC11 gene from 6/16 species (see all 16) About this table
ENSEMBL Gene Tree for ANAPC11 (if available) TreeFam Gene Tree for ANAPC11 (if available)  |
Paralogs for ANAPC11 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for ANAPC11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ANAPC11 (79848666 - 79858867 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for ANAPC11 5 CNVs: 23319 30036 7175 73078 5041  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANAPC11 |
|
Disorders
/ Diseases for ANAPC11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANAPC11 for disorders About GeneDecksing
OMIM gene information: 614534
OMIM disorders: --
5 diseases for ANAPC11: About MalaCardshepatocellular carcinoma molluscum contagiosum carcinoma intrahepatic cholangiocarcinoma cholangiocarcinoma Export disorders for ANAPC11 gene to outside databases
|
Publications for ANAPC11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANAPC11 gene, integrated from 9 sources (see all 49): (articles sorted by number of sources associating them with ANAPC11) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex. (PubMed id 10922056)1, 2, 3 Gmachl M....Peters J.M. (2000)
- Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p. (PubMed id 11573242)1, 2, 9 Chan A.H.... Tsui S.K.W. (2001)
- Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. (PubMed id 18485873)1, 2 Jin L....Rape M. (2008)
- Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PubMed id 16364912)1, 2 Dube P.... Stark H. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- APC2 cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. (PubMed id 11739784)1, 2 Tang Z.... Yu H. (2001)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- The RING-H2-finger protein APC11 as a target of hydrogen peroxide. (PubMed id 15256223)1, 9 Chang T.S....Rhee S.G. (2004)
- ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. (PubMed id 10230407)1, 9 Ohta T.... Xiong Y. (1999)
- Recombinant expression, reconstitution and structure o f human anaphase-promoting complex (APC/C). (PubMed id 23078409)1 Zhang Z....Barford D. (2013)
|
External Searches for ANAPC11 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ANAPC11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANAPC11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANAPC11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ANAPC11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANAPC11 gene: Search GeneIP for patents involving ANAPC11
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ANAPC11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ANAPC11 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANAPC11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANAPC11 | | OriGene Protein Over-expression Lysate for ANAPC11 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ANAPC11 | | OriGene 3'-UTR Clone for ANAPC11 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANAPC11 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for ANAPC11 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ANAPC11 | | OriGene Custom Protein Services for ANAPC11 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANAPC11 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANAPC11 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANAPC11 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANAPC11 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANAPC11 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANAPC11 |
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| | | Search Tocris compounds for ANAPC11 |
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 | | ANAPC11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANAPC11 |
|  |  |  | | | ThermoFisher Antibodies for ANAPC11 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANAPC11 |
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