Aliases for ANAPC11 Gene
- Anaphase Promoting Complex Subunit 11 2 3
- APC11 3 4 6
- Anaphase Promoting Complex Subunit 11 (Yeast APC11 Homolog) 2 3
- Hepatocellular Carcinoma-Associated RING Finger Protein 3 4
- Cyclosome Subunit 11 3 4
- APC11 Anaphase Promoting Complex Subunit 11 Homolog 3
- Anaphase-Promoting Complex Subunit 11 3
- HSPC214 3
- Apc11p 3
External Ids for ANAPC11 Gene
Previous GeneCards Identifiers for ANAPC11 Gene
GeneCards Summary for ANAPC11 Gene
ANAPC11 (Anaphase Promoting Complex Subunit 11) is a Protein Coding gene. Diseases associated with ANAPC11 include hepatocellular carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and PAK Pathway. GO annotations related to this gene include ubiquitin-protein transferase activity.
UniProtKB/Swiss-Prot for ANAPC11 Gene
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.