Aliases for AMZ2 Gene
External Ids for AMZ2 Gene
Previous GeneCards Identifiers for AMZ2 Gene
The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
GeneCards Summary for AMZ2 Gene
AMZ2 (Archaelysin Family Metallopeptidase 2) is a Protein Coding gene. Diseases associated with AMZ2 include Sertoli Cell-Only Syndrome. GO annotations related to this gene include metallopeptidase activity. An important paralog of this gene is AMZ1.
UniProtKB/Swiss-Prot for AMZ2 Gene
Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.