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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AMY1A Gene

protein-coding   GIFtS: 55
GCID: GC01P104197

amylase, alpha 1A (salivary)

(Previous names: amylase, alpha 1A; salivary )
(Previous symbol: AMY1)
 Explore 8 diseases affiliated with
AMY1A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for AMY1A    

Aliases
for AMY1A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Amylase, Alpha 1A (Salivary)1 2     Amylase, Alpha 1A; Salivary1
AMY11 2 3     Alpha-Amylase 12
Salivary Alpha-Amylase2 3     Amylase, Salivary, Alpha-1A2
1,4-Alpha-D-Glucan Glucanohydrolase 12 3     Glycogenase1
EC 3.2.1.13 8     Salivary Amylase Alpha 1A2

External Ids:    HGNC: 4741   Entrez Gene: 2762   Ensembl: ENSG000002377637   OMIM: 1047005   UniProtKB: P047453   

Export aliases for AMY1A gene to outside databases

Previous GC identifers: GC01P104923 GC01P105126 GC01P103252 GC01P103647 GC01P103553 GC01M103942 GC01P103999 GC01P102238


Summaries
for AMY1A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for AMY1A:
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and
thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several
amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase
isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the
same protein. (provided by RefSeq, Jul 2008)

Gene Wiki entry for AMY1A


Genomic Views
for AMY1A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
 Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AMY1A gene promoter:
         Sox5   Pbx1a   FOXJ2 (long isoform)   Sox9   FOXJ2   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: AMY1A promoter sequence
   Search SABiosciences Chromatin IP Primers for AMY1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMY1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p21   Ensembl cytogenetic band:  1p21.1   HGNC cytogenetic band: 1p21

AMY1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMY1A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P104197:  view genomic region     (about GC identifiers)

Start:
 104,197,912 bp from pter      End:
 104,207,173 bp from pter
Size:
 9,262 bases      Orientation:
 plus strand

Proteins
for AMY1A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: AMY1_HUMAN, P04745 (See protein sequence)
Recommended Name: Alpha-amylase 1 precursor  
Size: 511 amino acids; 57768 Da
Cofactor: Binds 1 calcium ion per subunit
Cofactor: Binds 1 chloride ion per subunit
Subunit: Monomer
Subcellular location: Secreted
6/13 PDB 3D structures from and Proteopedia for AMY1A (see all 13):
1C8Q (3D)        1JXJ (3D)        1JXK (3D)        1MFU (3D)        1MFV (3D)        1NM9 (3D)    
Secondary accessions: A6NJS5 A8K8H6 Q13763 Q5T083

Explore the universe of human proteins at neXtProt for AMY1A: NX_P04745

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P04745

    • 4/22 DME Specific Peptides for AMY1A (P04745) (see all 22)
     YMNHLID  GVRIYVD  YCDVISG  DNHDNQR 

    AMY1A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001008222.1  NP_004029.2  

    ENSEMBL proteins: 
     ENSP00000399836   ENSP00000359100   ENSP00000408386  
    Reactome Protein details: P04745
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    Uscn Proteins for AMY1A

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----


    AMY1A for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for AMY1A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    AMY1A for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR006046 Alpha_amylase
     IPR015902 Glyco_hydro_13
     IPR006048 A-amylase_b_C
     IPR017853 Glycoside_hydrolase_SF
     IPR006589 Glyco_hydro_13_sub_cat_dom

    Graphical View of Domain Structure for InterPro Entry P04745

    ProtoNet protein and cluster: P04745

    3 Blocks protein families:
    IPB006046 Alpha-amylase signature
    IPB006048 Alpha amylase
    IPB006589 Alpha amylase


    UniProtKB/Swiss-Prot: AMY1_HUMAN, P04745
    Similarity: Belongs to the glycosyl hydrolase 13 family


    Function
    for AMY1A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: AMY1_HUMAN, P04745
    Catalytic activity: Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more
    (1->4)-alpha-linked D-glucose units

         Genatlas biochemistry entry for AMY1A:
    amylase,alpha-1A,salivary,see AMY@

    Enzyme Number (IUBMB): EC 3.2.1.11 2

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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004556alpha-amylase activity ----
    GO:0005515protein binding ----
    GO:0043169cation binding ----
    GO:0046872metal ion binding ----


    AMY1A for ontologies           About GeneDecksing


    Animal Models:
         1 MGI phenotypic allele for Amy1 (no phenotypes)

    AMY1A for phenotypes           About GeneDecksing


    Pathways & Interactions
    for AMY1A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Metabolism
    		Metabolism1.00
    		Metabolic pathways0.38
    2Digestion of dietary carbohydrate
    		Digestion of dietary carbohydrate1.00
    3MPS IIIC - Sanfilippo syndrome C
    		Metabolism of carbohydrates0.47
    4Carbohydrate digestion and absorption
    		Carbohydrate digestion and absorption1.00
    5Glucuronidation
    		Starch and sucrose metabolism0.42

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for AMY1A
        Metabolism of carbohydrates
    Digestion of dietary carbohydrate
    Metabolism


    4         Kegg Pathways  (Kegg details for AMY1A):
        Starch and sucrose metabolism
    Metabolic pathways
    Salivary secretion
    Carbohydrate digestion and absorption


    AMY1A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AMY1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/21 Interacting proteins for AMY1A (P047451, 3 ENSP000003591004) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MUC7Q8TAX71, 3, ENSP000003020214EBI-738586,EBI-738582 I2D: score=2 STRING: ENSP00000302021
    AKAP1Q926673, ENSP000003377364I2D: score=2 STRING: ENSP00000337736
    AKAP8O438233, ENSP000002697014I2D: score=2 STRING: ENSP00000269701
    SOD2P041793, ENSP000003371274I2D: score=1 STRING: ENSP00000337127
    MUC5BQ9HC843, ENSP000004157934I2D: score=1 STRING: ENSP00000415793
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process ----
    GO:0007586digestion ----


    AMY1A for ontologies           About GeneDecksing



    Drugs & Compounds
    for AMY1A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AMY1A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for AMY1A

    10 HMDB Compounds for AMY1A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Alpha-D-GlucoseHexopyranose (see all 11)492-62-6--
    CalciumCa (see all 2)7440-70-2--
    ChlorineCl2 (see all 13)16887-00-6--
    D-Maltosealpha-Malt sugar (see all 40)69-79-4--
    DextrinCaloreen (see all 10)9004-53-9--
    GlycogenAnimal starch (see all 5)9005-79-2--
    MaltodecaoseB-cyclodextrin (see all 19)37331-89-8--
    Maltoheptaosemaltoheptose;alpha-D-Glc-(1->4)-alpha-D-Glc-(1->4)-alpha-D-Glc-(1->4)-alpha-D-Glc-(1->4)-alpha-D-Glc-(1->4)-alpha-D-Glc-(1->4)-D-Glc;Glc(alpha1-4)Glc(alpha1-4)Glc(alpha1-4)Glc(alpha1-4)Glc(alpha1-4)Glc(alpha1-4)Glc 34620-77-4--
    Maltononaosemaltonanoose 6471-60-9--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    5 DrugBank Compounds for AMY1A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    4,6-Dideoxy-4-Amino-Alpha-D-Glucose-- --target--17139284 17016423
    5-Hydroxymethyl-Chonduritol-- --target--17139284 17016423
    Beta-D-Glucose-- 50-99-7target--17139284 17016423
    Pyroglutamic Acid-- 98-79-3target--17139284 17016423
    Tris(Hydroxyethyl)Aminomethane-- --target--17139284 17016423

    4 Novoseek chemical compound relationships for AMY1A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    maltoheptaose 86.2 1 14511369 (1)
    amylose 80.6 3 11737209 (1), 16030022 (1), 14511369 (1)
    starch 74.5 7 11737209 (1), 17828263 (1), 12906828 (1), 14660599 (1) (see all 6)
    acarbose 73.1 3 14511369 (2)

    Search CenterWatch for drugs/clinical trials and news about AMY1A / AMY1 

    Transcripts
    for AMY1A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for AMY1A gene (2 alternative transcripts): 
    NM_001008221.1  NM_004038.3  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000430659 ENST00000370083(uc001duu.3 uc001duv.3) ENST00000422549
    ENST00000461518 ENST00000494409

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    Clone
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    24/283 AceView cDNA sequences (see all 283):

    CB956855 CB985770 CB985352 BI520380 BC069347 CB957282 AA367524 AA367514 
    CB957283 CB985304 BC070302 AI275811 BC069463 AA455195 CB958710 BV203900 
    BV192131 CB986084 CB986796 CB957519 CB958322 AI564596 CB957292 CB958306 

    GeneLoc Exon Structure


    Expression
    for AMY1A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AMY1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    AMY1A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    AdiposeBody Subcutaneous White AdiposeAdipose
    AdiposeVisceral White AdiposeAdipose
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See AMY1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AMY1A
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    In Situ
    Assay Products:     
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    Orthologs
    for AMY1A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for AMY1A gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves F1NF53_CHICK6
    F1NW02_CHICK6
    		 amylase, alpha 1A salivary
    		 83(a)
    79(a)
    		 many ↔ many
    many ↔ many
    		 8(38904-43343)
    8(11738273-11744621)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 79(a)
    		 1 → many
    		 4(85539622-85554936)
    zebrafish
    (Danio rerio)    		 Actinopterygii amy2a6
    zgc:921376
    (see all 3)    		 zgc:92137
    (see all 3)    		 74(a)
    69(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 2(15433338-15447555)
    17(42998722-43003011)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Amy-p1 , 3 alpha-amylase3
    Amylase proximal1    		 52(a)
    (best of 3)3
    56.28(n)1
    57.05(a)1    		   2 53F123
    477641  NM_080421.31  NP_536346.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea C50B6.73
    CELE_C50B6.71    		 amylase3
    Protein C50B6.71    		 44(a)3
    54.99(n)1
    49.59(a)1    		   V(13325025-13327571)3
    1798131  NM_073902.21  NP_506303.11 


    ENSEMBL Gene Tree for AMY1A (if available)
    TreeFam Gene Tree for AMY1A (if available) 

    Paralogs
    for AMY1A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AMY1A gene
    AMY1C1 2  AMY1B1 2  AMY2A2  AMY2B2  
    4 SIMAP similar genes for AMY1A using alignment to 4 protein entries:     AMY1_HUMAN (see all proteins):
    AMY1B    AMY1C    AMY2B    AMY2A

    AMY1A for paralogs           About GeneDecksing



    Genomic Variants
    for AMY1A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    9 NCBI SNPs in AMY1A are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1504051911,2
    		C,F--104203041(+) GGATAA/TCCATG 4 N I mis12Minor allele frequency- T:0.00NA EU 4455
    rs1387049231,2
    		C,F--104203066(+) CATGGC/TGCTGG 4 G syn12Minor allele frequency- T:0.00NA EU 4865
    rs1445314841,2
    		F--104203106(+) CTAGGT/CAAAAA 2 -- spd11Minor allele frequency- C:0.00NA 3932
    rs1381723551,2
    		----104203053(+) CAATCA/GACGAG 4 Q R mis11Minor allele frequency- G:0.00NA 3470
    rs2002556671,2
    		----104202939(+) ACTATT/AGTGAA 2 -- int11Minor allele frequency- A:0.00EU 809
    rs2008011901,2
    		----104204568(+) TATTCC/TCATTT 2 -- int10--------
    rs1996182411,2
    		----104203534(+) TAGCCC/TGCAGG 2 -- int10--------
    rs2012881841,2
    		----104203023(+) CAGAGC/TGCTTG 4 A V mis11Minor allele frequency- T:0.00EU 1217
    rs2014399931,2
    		----104203246(+) TGGATT/ATACAC 4 /Y /F mis11Minor allele frequency- A:0.00EU 877

    HapMap Linkage Disequilibrium report for AMY1A (104197912 - 104207173 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 17 variations for AMY1A
         15/16 CNVs (see all 16): 69238 69229 0012 3302 0681 30393 2048 84396 48067 48068 74585 84395 69236 31636 4238
         1 Inversion: 37075

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    Disorders / Diseases
    for AMY1A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    AMY1A for disorders           About GeneDecksing

    OMIM gene information: 104700    OMIM disorders: --

    8 diseases for AMY1A:    About MalaCards
    ovarian serous cystadenocarcinoma    serous cystadenocarcinoma    dental caries    sialadenitis
    mucoepidermoid carcinoma    cystadenocarcinoma    pancreatitis    carcinoma

    Genetic Association Database (GAD): AMY1A
    Human Genome Epidemiology (HuGE) Navigator: AMY1A (1 document)

    Export disorders for AMY1A gene to outside databases

    Publications
    for AMY1A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AMY1A gene, integrated from 9 sources (see all 60):
    (articles sorted by number of sources associating them with AMY1A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (2006)
    2. On the genetic polymorphism of the serum alpha-amylase in the population of the south western Bulgaria (second communication). (PubMed id 16152770)1, 4 Baltova S.D. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase. (PubMed id 12527308)1, 2 Ramasubbu N.... Mishra P.J. (2003)
    5. Structure of human salivary alpha-amylase at 1.6-A resolution: implications for its role in the oral cavity. (PubMed id 15299664)1, 2 Ramasubbu N.... Levine M.J. (1996)
    6. Electrophoretic characterization of posttranslational modifications of human parotid salivary alpha-amylase. (PubMed id 1710976)1, 2 Bank R.A.... Pronk J.C. (1991)
    7. Concerted evolution of human amylase genes. (PubMed id 2452973)1, 2 Gumucio D.L....Meisler M.H. (1988)
    8. Identification of a human salivary amylase gene. Partial sequence of genomic DNA suggests a mode of regulation different from that of mouse, Amy1. (PubMed id 2442579)1, 2 Handy D.E.... Hodes M.E. (1987)
    9. Primary structure of human salivary alpha-amylase gene. (PubMed id 2423416)1, 2 Nishide T....Matsubara K. (1986)
    10. Corrected sequences of cDNAs for human salivary and pancreatic alpha- amylases. (PubMed id 6610603)1, 2 Nakamura Y....Matsubara K. (1984)

    External Searches for AMY1A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing AMY1A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 276 HGNC: 474 AceView: AMY1A Ensembl:ENSG00000237763 euGenes: HUgn276
    ECgene: AMY1A Kegg: 276 H-InvDB: AMY1A

    Other Databases showing AMY1A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing AMY1A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AMY1A Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Amylase

    Intellectual Property
    for AMY1A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for AMY1A gene:
    Search GeneIP for patents involving AMY1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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