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AMPH Gene

protein-coding   GIFtS: 62

GC07M038389
amphiphysin
(Previous names: amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen), amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for AMPH

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
AMPH1 2, 3
amphiphysin 2
Descriptions
Stiff-Man syndrome with breast cancer 128kDa autoantigen 2
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa
autoantigen) 1
amphiphysin (Stiff-Mann syndrome with breast cancer 128kD
autoantigen) 1, 2
External Ids
HGNC: 4711
Entrez Gene: 2732
UniProtKB: P494183
Ensembl: ENSG000000780537
Search outside databases for aliases for AMPH gene

Previous GC identifers: GC07M038069 GC07M038130 GC07M038164 GC07M038196

Summaries
for AMPH

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for AMPH:
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset
of patients with stiff-man syndrome who were also affected by breast cancer are positive for
autoantibodies against this protein. Alternate splicing of this gene results in two transcript
variants encoding different isoforms. Additional splice variants have been described, but their
full length sequences have not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418
Function: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine
cell types. May control the properties of the membrane associated cytoskeleton

Gene Wiki entry for AMPH (Amphiphysin)

Genomic Location
for AMPH

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the AMPH gene  

Entrez Gene cytogenetic band: 7p14-p13   Ensembl cytogenetic band:  7p14.1   HGNC cytogenetic band: 7p14-p13

AMPH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M038389:     (about GC identifiers)

Start:
 38,389,830 bp from pter
End:
 38,637,545 bp from pter
Size:
 247,716 bases
Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 38,460,977-38,708,687     
RefSeq DNA sequence:
NC_000007.12  NT_007819.16  NT_079592.2  

Proteins
for AMPH

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418 (See protein sequence)
Recommended Name: Amphiphysin  
Size: 695 amino acids; 76257 Da
Subunit: Heterodimer with BIN1. Binds SH3GLB1 and AP2A2 (By similarity)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral
membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton
PDB structure from and Proteopedia :
1KY7 (3D)    1UTC (3D)    
Secondary accessions: O43538 Q75MJ8 Q75MK5 Q75MM3 Q8N4G0
Alternative splicing: 2 isoforms:  P49418-1   P49418-2   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001626.1  NP_647477.1  


    ENSEMBL proteins: 
    ENSP00000342268 ENSP00000317441 ENSP00000348602 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Amphiphysin)
    Human Recombinant Proteins from Abnova (AMPH)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IEA--
    GO:0008021 synaptic vesicle TAS1628617
    GO:0015629 actin cytoskeleton TAS9182667
    GO:0016020 membrane IEA--
    GO:0030054 cell junction IEA--
    About this table

    Antibodies for AMPH: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for AMPH
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Amphiphysin), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (AMPH)
    Novus Biologicals Antibodies for AMPH

    Assays for AMPH: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for AMPH

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro domains/families:
     IPR003017 Amphiphysin_1
     IPR001452 SH3_domain
     IPR004148 BAR
     IPR003005 Amphiphysin


       GeneDecks  AMPH for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P49418

    ProtoNet protein and cluster: P49418

    3 Blocks protein families:
    IPB001452 SH3 domain signature
    IPB003005 Amphiphysin signature
    IPB003017 Amphiphysin isoform 1 signature


    UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418
    Similarity: Contains 1 BAR domain
    Similarity: Contains 1 SH3 domain

    Gene Function
    for AMPH

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (AMPH)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (AMPH)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_139316

                  Applied Biosystems Silencer® siRNAs for AMPH

                  Sigma-Aldrich siRNA for AMPH  
                         Sigma-Aldrich shRNA Panels and shRNA for AMPH  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for AMPH
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001635
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001635
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_001635 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001635

    UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418
    Function: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine
    cell types. May control the properties of the membrane associated cytoskeleton

    Genatlas biochemistry entry for AMPH:
    amphiphysin,nerve terminal,synaptic vesicle associated antigen,involved in synaptic vesicle
    endocytosis in the nerve terminals,by binding to the coat protein adaptor

    4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Amph):

    behavior/neurologicalhomeostasis/metabolismlife span-post-weaning/agingnervous system

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515 protein binding IEA--
    About this table

    Pathways & Interactions
    for AMPH

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  AMPH  (Your Favorite Gene powered by Ingenuity) 
     Clathrin-mediated Endocytosis

       GeneDecks  AMPH for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  AMPH 


    5/40 Interacting proteins for AMPH (P494182 ENSP000003174413) via UniProtKB, MINT, and/or STRING (see all 40 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNM1Q051932, ENSP000003620143MINT-18828 MINT-18829 MINT-65945 STRING (score=.999)
    DNM2P505702, ENSP000003131643MINT-2516534 MINT-65956 STRING (score=.996)
    SYNJ1O434262, ENSP000003719313MINT-16056 STRING (score=.996)
    CLTCENSP000002691223STRING (score=.995)
    SH3GL2ENSP000003699813STRING (score=.994)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007268 synaptic transmission TAS9182667
    GO:0007612 learning IEA--
    GO:0048488 synaptic vesicle endocytosis IEA--
    About this table

    Drugs & Compounds
    for AMPH

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for AMPH
    4 Novoseek chemical compound relationships for AMPH gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    lipid 7.86 3 10559861 (1), 11604418 (1)
    proline 3.29 4 10542231 (2), 14529717 (1)
    calcium 0.00 6 18824588 (2), 9651678 (1), 9925188 (1), 11157570 (1)
    phosphatidylinositol 0.00 1 10542231 (1)
    About this table


    Transcripts
    for AMPH

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (AMPH)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (AMPH)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_139316

                  Sigma-Aldrich siRNA for AMPH  
                         Sigma-Aldrich shRNA Panels and shRNA for AMPH  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001635  NM_139316  

    REFSEQ mRNAs for AMPH gene (2 alternative transcripts): 

    NM_001635.2   NM_139316.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001635  NM_139316  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001635
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001635
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_001635 

    Additional cDNA sequence: 

    AF034996.1 AF498092.1 AF498093.1 AF498094.1 AF498095.1 AF498096.1 AF498097.1 AK291447.1 
    BC034376.1 U07616.1 X81438.1 

    8 DOTS entries:

    DT.95265452  DT.216480  DT.100778700  DT.95265450  DT.100024283  DT.100024285  DT.100024288  DT.121071504 

    24/82 AceView cDNA sequences (see all 82 ):

    AA757605 F06517 AA349856 BI822061 AF034996 AF498096 F03887 AF498092 
    F03327 F10677 AA933764 Z39467 AL119578 BM929628 NM_001635 BC034376 
    F03194 BM673566 BM978301 AA620426 NM_139316 AF498097 AF498094 BI552938 

    highest scoring ESTs for AMPH:

    U07616 AF034996 AF498097 AW160829 BC034376 BI822061 BM543458 X81438 AA349856 AA620426 

    Unigene Cluster for AMPH:

    Amphiphysin
    Hs.592182  [show with all ESTs]
    Unigene Representative Sequence: NM_001635


    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for AMPH

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                          -                           
    SP2:                                                      
    SP3:                                                      

    About this scheme

    ECgene alternative splicing isoforms for AMPH

    3 Ensembl transcripts including schematic representations:
    ENST00000353242  ENST00000325590  ENST00000356264  

    Expression
    for AMPH

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    AMPH expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for AMPH

    1 / 2 / 3

    3 probe-sets matching AMPH gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32728_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 U07616 1.00 0.90 0.95 1

    		205257_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001635 0.60 1.00 0.82 1

    		205257_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  AMPH for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: CATTGCTCTT

    SOURCE GeneReport for Unigene cluster: Hs.592182

    Expression variation in blood from EXPOLDB for AMPH

    UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418
    Tissue specificity: Neurons, certain endocrine cell types and spermatocytes

    Orthologs
    for AMPH

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for AMPH gene from 5/9 species (see all 9 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    cow
    (Bos taurus)    		 AMPH1   -- amphiphysin 92.33(n)
    98.2(a)    		 788695  XM_001255675.1  XP_001255676.1 
    rat
    (Rattus norvegicus)    		 Amph1   -- amphiphysin 85.53(n)
    88.12(a)    		 60668  NM_022217.1  NP_071553.1 
    mouse
    (Mus musculus)    		 Amph1, 5 13 (10.00 cM)5
    		 amphiphysin1, 5 84.8(n)1
    86.7(a)1    		 2180381  NM_175007.11  NP_778172.11 
     AK0471445  AK1321685  (see all 10)
    chicken
    (Gallus gallus)    		 AMPH1   -- amphiphysin 73.01(n)
    75.19(a)    		 420761  NM_001004398.1  NP_001004398.1 
    zebrafish
    (Danio rerio)    		 zgc731932   -- hypothetical protein MGC73193 79.18(n) 393804  BC060916.1 
    About this table        Species with no ortholog for AMPH

    ENSEMBL Gene Tree for AMPH

    Paralogs
    for AMPH

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for AMPH gene
    BIN12  BIN22  

    SNPs/Variants
    for AMPH

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/1789 NCBI SNPs in AMPH are shown (see all 1789 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 619)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 7 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs28101,2
    		C,F,H,O38390853(-) TCTTAA/GTGATT 2 -- ut3119Minor allele frequency- G:0.10MN EU EA WA NA 1854
    rs22411141,2
    		A,C,F,H38390239(+) TTTTGG/CCAATG 2 -- ut31 ese315Minor allele frequency- C:0.35NA EU EA WA 1340
    rs171713451,2
    		C,F,H38442403(+) TGAGAC/GATGGG 2 M/I mis1 ese312Minor allele frequency- G:0.02NA EU EA WA 1054
    rs174975441,2
    		C,F,H38389395(+) CTCTTT/CTGGAA 2 -- ng5111Minor allele frequency- C:0.05NA EU EA WA 982
    rs20725051,2
    		C,F,H38390564(+) CTTGTA/GCTACA 2 -- ut31 ese311Minor allele frequency- G:0.20NA EU EA WA 972
    rs69605501,2
    		F,H38390590(+) TCTTCT/GGCAGG 2 -- ut31 ese34Minor allele frequency- G:0.13EU EA WA 420
    rs350246321,2
    		C,F38400251(+) TGGCCT/GTCTCC 2 T/K mis15Minor allele frequency- G:0.11NA EU EA WA 496
    --
    rs69691061,2
    		F,H38389407(+) TAATGG/ACCAAG 2 -- ng514Minor allele frequency- A:0.01EU EA WA 418
    rs351663541,2
    		C,F38472312(+) TTCCTT/CATGAA 2 E/K mis15Minor allele frequency- C:0.00NA EU EA WA 494
    rs10586551,2
    		C,F,H38398006(-) ACACCG/TGAGCT 2 P/P syn1 ese315Minor allele frequency- T:0.17MN EA NA EU WA 1312
    About this table

    HapMap Linkage Disequilibrium images for AMPH (up to first 250kb)

    Disorders & Mutations
    for AMPH

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 600418

    UniProtKB/Swiss-Prot: AMPH_HUMAN, P49418
  • Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease
    of the central nervous system characterized by progressive rigidity of the body musculature with
    superimposed painful spasms

    • 10/11 Novoseek disease relationships for AMPH gene (see all 11 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    stiff-man syndrome 90.28 14 7757077 (2), 15836889 (2), 8076697 (2), 18971449 (2) (see all 9)
    paraneoplastic syndromes 71.91 3 9443464 (1), 12846868 (1), 19398941 (1)
    autoimmunity 57.38 11 14755734 (2), 8245793 (1), 9443464 (1), 7757077 (1) (see all 10)
    rare disease 33.26 1 18971449 (1)
    autoimmune diseases 32.58 2 15836889 (1), 11748137 (1)
    breast carcinoma 27.31 2 8619552 (1), 12846868 (1)
    breast cancer 27.29 9 8076697 (2), 9443464 (1), 18971449 (1), 12846868 (1) (see all 8)
    lung carcinoma 26.73 1 8619552 (1)
    cancer 3.16 3 9513187 (1), 14755734 (1)
    neurological disorders 0.00 1 16567945 (1)
    About this table

    Medical News
    for AMPH

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for AMPH

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/131 PubMed articles for AMPH gene (see all 131 ):

    Search for AMPH

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing AMPH

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 273 HGNC: 471 AceView: AMPH Ensembl:ENSG00000078053 euGenes: HUgn273
    ECgene: AMPH H-InvDB: AMPH

    Other Databases showing AMPH

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing AMPH

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for AMPH Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for AMPH

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for AMPH

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for AMPH:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for AMPH-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for AMPH Antibodies for AMPH
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for AMPH Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
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     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (AMPH)
     Antibodies (AMPH)
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     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Amphiphysin)
     Antibodies (Amphiphysin)
     Search OriGene for AMPH
     Search Tocris compounds for AMPH




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for AMPH

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    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    AMPH Gene at Home site.
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