Aliases for AMPD3 Gene
Aliases for AMPD3 Gene
External Ids for AMPD3 Gene
- HGNC: 470
- Entrez Gene: 272
- Ensembl: ENSG00000133805
- OMIM: 102772
- UniProtKB: Q01432
Previous GeneCards Identifiers for AMPD3 Gene
- GC11P011483
- GC11P011042
- GC11P010511
- GC11P010436
- GC11P010428
- GC11P010144
Summaries for AMPD3 Gene
-
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for AMPD3 Gene
AMPD3 (Adenosine Monophosphate Deaminase 3) is a Protein Coding gene. Diseases associated with AMPD3 include Adenosine Monophosphate Deaminase Deficiency Erythrocyte Type and Adenosine Monophosphate Deaminase 1 Deficiency. Among its related pathways are Purine metabolism (REACTOME) and Innate Immune System. GO annotations related to this gene include deaminase activity and AMP deaminase activity. An important paralog of this gene is AMPD1.
UniProtKB/Swiss-Prot for AMPD3 Gene
-
AMP deaminase plays a critical role in energy metabolism.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMPD3 Gene
Genomics for AMPD3 Gene
Regulatory Elements for AMPD3 Gene
Enhancers for AMPD3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AMPD3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the AMPD3 gene promoter:
Regulatory Element Products
Genomic Location for AMPD3 Gene
- Chromosome:
- 11
- Start:
- 10,308,313 bp from pter
- End:
- 10,507,579 bp from pter
- Size:
- 199,267 bases
- Orientation:
- Plus strand
Genomic View for AMPD3 Gene
Genes around AMPD3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by Ensembl
- 11p15.4 by Entrez Gene
- 11p15.4 by HGNC
AMPD3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AMPD3 Gene
Proteins for AMPD3 Gene
-
Protein details for AMPD3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q01432-AMPD3_HUMAN
- Recommended name:
- AMP deaminase 3
- Protein Accession:
- Q01432
- A0AUX0
- B7Z2S2
- B7Z763
- B7Z877
Protein attributes for AMPD3 Gene
- Size:
- 767 amino acids
- Molecular mass:
- 88812 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
-
- Homotetramer.
Protein Expression for AMPD3 Gene
Selected DME Specific Peptides for AMPD3 Gene
- Q01432:
-
- RPHCGEAG
- QNPPYSYYLYY
- QFHYTKE
- PHRDFYN
- TFHRFDKFN
Post-translational modifications for AMPD3 Gene
Other Protein References for AMPD3 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for AMPD3
- Novus Biologicals Antibodies for AMPD3
-
Abcam antibodies for AMPD3
- Invitrogen Antibodies for AMPD3
- antibodies-online Antibodies for AMPD3: See all 28
- GeneTex AMPD3 antibody for AMPD3
Protein Products
-
OriGene Purified Proteins for AMPD3
- Search Origene for MassSpec and Protein Over-expression Lysates for AMPD3
- Origene Custom Protein Services for AMPD3
- antibodies-online Proteins for AMPD3: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for AMPD3
-
Abcam proteins for AMPD3
Assay Products
- antibodies-online Kits for AMPD3: See all 4
Domains & Families for AMPD3 Gene
Gene Families for AMPD3 Gene
Protein Domains for AMPD3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for AMPD3 Gene
Graphical View of Domain Structure for InterPro Entry
Q01432- Family:
-
- Belongs to the adenosine and AMP deaminases family.
Function for AMPD3 Gene
Molecular function for AMPD3 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- AMP + H(2)O = IMP + NH(3).
- UniProtKB/Swiss-Prot Function:
- AMP deaminase plays a critical role in energy metabolism.
Enzyme Numbers (IUBMB) for AMPD3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003876 | AMP deaminase activity | EXP | 1429593 |
| GO:0005515 | protein binding | IPI | 25910212 |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0019239 | deaminase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for AMPD3 Gene
- MGI mutant phenotypes for AMPD3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for AMPD3:
-
- Increased vaccinia virus (VACV) infection
- Dynamic nuclei (hole, folded or small irregular)
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased viability with neratinib
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMPD3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AMPD3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD3 gene
- Search ViGene Biosciences for AMPD3
CRISPR Products
-
OriGene CRISPR knockouts for AMPD3
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPD3
- GenScript: Design CRISPR guide RNA sequences for AMPD3
miRNA for AMPD3 Gene
- miRTarBase miRNAs that target AMPD3
-
- hsa-mir-335-5p (MIRT018876)
- hsa-mir-7975 (MIRT497133)
- hsa-mir-3143 (MIRT609670)
- hsa-mir-8485 (MIRT609671)
- hsa-mir-543 (MIRT609672)
- hsa-mir-548x-3p (MIRT613544)
- hsa-mir-548j-3p (MIRT613545)
- hsa-mir-548aq-3p (MIRT613546)
- hsa-mir-548am-3p (MIRT613547)
- hsa-mir-548aj-3p (MIRT613548)
- hsa-mir-548ah-3p (MIRT613549)
- hsa-mir-548ae-3p (MIRT613550)
- hsa-mir-548z (MIRT613551)
- hsa-mir-548h-3p (MIRT613552)
- hsa-mir-548d-3p (MIRT613553)
- hsa-mir-548bb-3p (MIRT613554)
- hsa-mir-548ac (MIRT613555)
miRNA Products
- Search ViGene Biosciences for AMPD3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for AMPD3
- Browse OriGene Inhibitory RNA Products For AMPD3
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD3 gene
Clone Products
-
OriGene ORF clones in human for AMPD3
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- VectorBuilder custom plasmid, inducible vectors for AMPD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for AMPD3
-
ViGene Biosciences adenoviral particle packaged cDNA for AMPD3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AMPD3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD3 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for AMPD3 Gene
Localization for AMPD3 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| extracellular | 4 |
| nucleus | 4 |
| mitochondrion | 2 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0034774 | secretory granule lumen | TAS | -- |
| GO:1904813 | ficolin-1-rich granule lumen | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for AMPD3 Gene
Pathways & Interactions for AMPD3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Purine metabolism (REACTOME) |
.01
|
|
| 3 | Metabolism |
.37
|
|
| 4 | Purine metabolism (KEGG) | ||
Pathways by source for AMPD3 Gene
7 Reactome pathways for AMPD3 Gene
2 KEGG pathways for AMPD3 Gene
1 GeneGo (Thomson Reuters) pathway for AMPD3 Gene
UniProtKB/Swiss-Prot Q01432-AMPD3_HUMAN
- Pathway: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.
Interacting Proteins for AMPD3 Gene
Selected Interacting proteins:
ENSP00000379802
Q01432-AMPD3_HUMAN
for AMPD3 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006188 | IMP biosynthetic process | IEA | -- |
| GO:0006196 | AMP catabolic process | TAS | 9291127 |
| GO:0009117 | nucleotide metabolic process | IEA | -- |
| GO:0009168 | purine ribonucleoside monophosphate biosynthetic process | IEA | -- |
| GO:0032264 | IMP salvage | IEA | -- |
No data available for SIGNOR curated interactions for AMPD3 Gene
Drugs & Compounds for AMPD3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Cladribine | Approved, Investigational | Pharma | Apoptosis inducer in CLL cells | 73 | ||
| Propranolol | Approved, Investigational | Pharma | Antagonist | Beta blocker | 228 | |
| Water | Approved | Pharma | 0 | |||
| Adenosine monophosphate | Approved | Nutra | 0 | |||
| Inosinic acid | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Ammonia |
|
7664-41-7 |
|
(1) ApexBio Compounds for AMPD3 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Cladribine | Apoptosis inducer in CLL cells | 4291-63-8 |
Drug Products
- ApexBio compounds for AMPD3
Transcripts for AMPD3 Gene
mRNA/cDNA for AMPD3 Gene
- (5) REFSEQ mRNAs :
- (17) Additional mRNA sequences :
- (186) Selected AceView cDNA sequences:
- (18) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for AMPD3 Gene
- Adenosine monophosphate deaminase 3:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for AMPD3
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPD3
- GenScript: Design CRISPR guide RNA sequences for AMPD3
miRNA Products
- Search ViGene Biosciences for AMPD3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for AMPD3
- Browse OriGene Inhibitory RNA Products For AMPD3
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD3 gene
Clone Products
-
OriGene ORF clones in human for AMPD3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AMPD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for AMPD3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
-
Peripheral Nervous System (Nervous System)
mRNA differential expression in normal tissues according to GTEx for AMPD3 Gene
This gene is overexpressed in Muscle - Skeletal (x8.8) and Whole Blood (x4.3).
This gene is overexpressed in Lymph node (49.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for AMPD3 Gene
NURSA nuclear receptor signaling pathways regulating expression of AMPD3 Gene:
AMPD3SOURCE GeneReport for Unigene cluster for AMPD3 Gene:
Hs.501890Evidence on tissue expression from TISSUES for AMPD3 Gene
- Nervous system(4.6)
- Skin(4.2)
- Muscle(2.7)
- Blood(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for AMPD3 Gene
Germ Layers:
- mesoderm
Systems:
- skeletal muscle
Primer Products
-
OriGene qPCR primer pairs for AMPD3
No data available for mRNA Expression by UniProt/SwissProt for AMPD3 Gene
Orthologs for AMPD3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AMPD3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | AMPD3 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AMPD3 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | AMPD3 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | AMPD3 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ampd3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ampd3 34 |
|
||
| chicken (Gallus gallus) |
Aves | AMPD3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | AMPD3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ampd3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ampd3a 35 |
|
OneToMany | |
| ampd3b 35 |
|
OneToMany | |||
| LOC556578 34 |
|
||||
| wufi25h10 34 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | C34F11.3a 36 |
|
|
|
| C34F11.3b 36 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AMD1 35 |
|
OneToMany | |
| barley (Hordeum vulgare) |
Liliopsida | Hv.6749 34 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.6820 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4939 34 |
|
- Species where no ortholog for AMPD3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for AMPD3 Gene
(2) SIMAP similar genes for AMPD3 Gene using alignment to 7 proteins:
Variants for AMPD3 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs117706710 | Benign, Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874] | 10,487,356(+) | ATAAC(C/G/T)TGAGA | reference, missense | |
| rs147542803 | Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874] | 10,493,368(+) | CCATG(C/T)GGCCG | reference, missense | |
| rs3741040 | other, Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874] | 10,500,245(+) | ACCTC(C/T)GCAGG | reference, missense | |
| rs748852415 | Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874] | 10,501,502(+) | CCGGC(C/G/T)GCACT | reference, missense | |
| rs750004231 | Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874] | 10,493,380(+) | CTGCA(C/T)GAACC | reference, missense |
Residual Variation Intolerance Score:
36.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.69;
66.03% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AMPD3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMPD3 Gene
Disorders for AMPD3 Gene
(5) MalaCards diseases for AMPD3 Gene - From: GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| adenosine monophosphate deaminase deficiency erythrocyte type |
|
|
| adenosine monophosphate deaminase 1 deficiency |
|
|
| erythrocyte amp deaminase deficiency |
|
|
| glycogen storage disease vii |
|
|
| mcardle disease |
|
Search AMPD3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
AMPD3_HUMAN- Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) [MIM:612874]: A metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders. {ECO:0000269 PubMed:11139257, ECO:0000269 PubMed:7881427, ECO:0000269 PubMed:8004104, ECO:0000269 PubMed:9598089}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for AMPD3
No data available for Genatlas for AMPD3 Gene
Publications for AMPD3 Gene
- Cloning of human AMP deaminase isoform E cDNAs. Evidence for a third AMPD gene exhibiting alternatively spliced 5'-exons. (PMID: 1400401) Mahnke-Zizelman D.K. … Sabina R.L. (J. Biol. Chem. 1992) 2 3 4 22 64
- A rare case of complete human erythrocyte AMP deaminase deficiency due to two novel missense mutations in AMPD3. (PMID: 11139257) Yamada Y. … Ogasawara N. (Hum. Mutat. 2001) 3 4 22 64
- Characterization of the human AMPD3 gene reveals that 5' exon useage is subject to transcriptional control by three tandem promoters and alternative splicing. (PMID: 8611627) Mahnke-Zizelman D.K. … Sabina R.L. (Biochim. Biophys. Acta 1996) 3 4 22 64
- A point mutation responsible for human erythrocyte AMP deaminase deficiency. (PMID: 8004104) Yamada Y. … Ogasawara N. (Hum. Mol. Genet. 1994) 3 4 22 64
- Cloning and nucleotide sequence of the cDNA encoding human erythrocyte-specific AMP deaminase. (PMID: 1420359) Yamada Y. … Ogasawara N. (Biochim. Biophys. Acta 1992) 3 4 22 64
Products for AMPD3 Gene
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- Novus Biologicals Antibodies for AMPD3
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- Novus Biologicals
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- Abcam proteins for AMPD3
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- Invitrogen Antibodies for AMPD3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for AMPD3
- antibodies-online Antibodies for AMPD3: See all 28
- antibodies-online Kits for AMPD3: See all 4
- antibodies-online Proteins for AMPD3: See all 6
- Search antibodies-online for peptides
- GeneTex AMPD3 antibody for AMPD3
- Search GeneTex for Proteins for AMPD3
- ViGene Biosciences adenoviral particle packaged cDNA for AMPD3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for AMPD3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for AMPD3 gene
- Search ViGene Biosciences for AMPD3
- Horizon Cell Lines for AMPD3
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMPD3
- VectorBuilder custom plasmid, inducible vectors for AMPD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AMPD3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
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