Aliases for AMPD1 Gene
Aliases for AMPD1 Gene
External Ids for AMPD1 Gene
- HGNC: 468
- Entrez Gene: 270
- Ensembl: ENSG00000116748
- OMIM: 102770
- UniProtKB: P23109
Previous GeneCards Identifiers for AMPD1 Gene
- GC01M115629
- GC01M114097
- GC01M114315
- GC01M114514
- GC01M114927
- GC01M115215
- GC01M113074
Summaries for AMPD1 Gene
-
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
GeneCards Summary for AMPD1 Gene
AMPD1 (Adenosine Monophosphate Deaminase 1) is a Protein Coding gene. Diseases associated with AMPD1 include Myopathy Due To Myoadenylate Deaminase Deficiency and Adenosine Monophosphate Deaminase 1 Deficiency. Among its related pathways are Purine metabolism (REACTOME) and Purine metabolism (KEGG). GO annotations related to this gene include deaminase activity and AMP deaminase activity. An important paralog of this gene is AMPD3.
UniProtKB/Swiss-Prot for AMPD1 Gene
-
AMP deaminase plays a critical role in energy metabolism.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMPD1 Gene
Genomics for AMPD1 Gene
Regulatory Elements for AMPD1 Gene
Enhancers for AMPD1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G114667 | 1.3 | ENCODE dbSUPER | 14.3 | +25.8 | 25795 | 3.7 | PKNOX1 ATF1 FOXA2 ARID4B BRCA1 ZNF2 ZNF48 YY1 ZNF121 GLIS2 | AMPD1 DENND2C TRIM33 TSPAN2 ENSG00000228035 LOC105378914 |
| GH01G114580 | 1.1 | ENCODE | 14 | +114.1 | 114073 | 2.4 | PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 | TRIM33 AMPD1 DENND2C RSBN1 BCAS2 LOC105378913 |
| GH01G115061 | 1.7 | FANTOM5 Ensembl ENCODE dbSUPER | 8.1 | -367.3 | -367297 | 2.3 | ZNF146 MXI1 TAF1 JUN MAX SIN3A EBF1 RFX5 ZNF507 ZKSCAN1 | TSPAN2 TSHB AMPD1 BCAS2 SIKE1 |
| GH01G114688 | 0.4 | dbSUPER | 29.9 | +6.6 | 6552 | 1.5 | ATF3 CEBPG | AMPD1 DENND2C |
| GH01G115067 | 1.2 | Ensembl ENCODE dbSUPER | 8.2 | -373.1 | -373106 | 3.4 | CTCF MAX USF2 CEBPB RAD21 EP300 FOXA1 CTBP1 JUND GATA3 | TSPAN2 TSHB AMPD1 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AMPD1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for AMPD1 Gene
- Chromosome:
- 1
- Start:
- 114,673,090 bp from pter
- End:
- 114,695,618 bp from pter
- Size:
- 22,529 bases
- Orientation:
- Minus strand
Genomic View for AMPD1 Gene
Genes around AMPD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.2 by Ensembl
- 1p13.2 by Entrez Gene
- 1p13.2 by HGNC
AMPD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AMPD1 Gene
Proteins for AMPD1 Gene
-
Protein details for AMPD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P23109-AMPD1_HUMAN
- Recommended name:
- AMP deaminase 1
- Protein Accession:
- P23109
- A8K5N4
- B2RAM1
- F2Z3B3
- Q5TF00
- Q5TF02
Protein attributes for AMPD1 Gene
- Size:
- 780 amino acids
- Molecular mass:
- 90219 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
-
- Homotetramer.
- SequenceCaution:
-
- Sequence=AAA57281.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAG24258.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAF84038.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG36918.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI18828.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for AMPD1 Gene
Selected DME Specific Peptides for AMPD1 Gene
- P23109:
-
- RPHCGEAG
- DADRVVY
- PHRDFYN
- DNYINGEY
Post-translational modifications for AMPD1 Gene
Other Protein References for AMPD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for AMPD1
- Novus Biologicals Antibodies for AMPD1
- Invitrogen Antibodies for AMPD1
- antibodies-online Antibodies for AMPD1: See all 68
- GeneTex AMPD1 antibody for AMPD1
-
Santa Cruz Biotechnology (SCBT) Antibodies for AMPD1
Protein Products
-
OriGene Purified Proteins for AMPD1
- Search Origene for MassSpec and Protein Over-expression Lysates for AMPD1
- Origene Custom Protein Services for AMPD1
- antibodies-online Proteins for AMPD1: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for AMPD1
Assay Products
- antibodies-online Kits for AMPD1: See all 4
Domains & Families for AMPD1 Gene
Gene Families for AMPD1 Gene
Protein Domains for AMPD1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for AMPD1 Gene
Graphical View of Domain Structure for InterPro Entry
P23109- Family:
-
- Belongs to the adenosine and AMP deaminases family.
Function for AMPD1 Gene
Molecular function for AMPD1 Gene
- GENATLAS Biochemistry:
- adenosine monophosphate deaminase 1 (isoform M,skeletal muscle),adenine nucleotide catabolic pathway,purine nucleotide cycle
- UniProtKB/Swiss-Prot CatalyticActivity:
- AMP + H(2)O = IMP + NH(3).
- UniProtKB/Swiss-Prot Function:
- AMP deaminase plays a critical role in energy metabolism.
Enzyme Numbers (IUBMB) for AMPD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003876 | AMP deaminase activity | EXP | 1429593 |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0019239 | deaminase activity | IEA | -- |
| GO:0032036 | myosin heavy chain binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for AMPD1 Gene
- MGI mutant phenotypes for AMPD1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for AMPD1:
Animal Models for AMPD1 Gene
- MGI Knock Outs for AMPD1:
-
- Ampd1 tm1b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMPD1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AMPD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD1 gene
- Search ViGene Biosciences for AMPD1
CRISPR Products
-
OriGene CRISPR knockouts for AMPD1
-
Applied Biological Materials CRISPR for AMPD1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPD1
- GenScript: Design CRISPR guide RNA sequences for AMPD1
miRNA for AMPD1 Gene
- miRTarBase miRNAs that target AMPD1
miRNA Products
- Search ViGene Biosciences for AMPD1
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD1 gene
Clone Products
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for AMPD1
-
ViGene Biosciences adenoviral particle packaged cDNA for AMPD1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AMPD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD1 gene
No data available for Transcription Factor Targets and HOMER Transcription for AMPD1 Gene
Localization for AMPD1 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| mitochondrion | 2 |
| nucleus | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for AMPD1 Gene
Pathways & Interactions for AMPD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Purine metabolism (REACTOME) |
.01
|
|
| 2 | Metabolism |
.37
|
|
| 3 | Purine metabolism (KEGG) | ||
| 4 | Immune response Function of MEF2 in T lymphocytes | ||
Pathways by source for AMPD1 Gene
4 Reactome pathways for AMPD1 Gene
2 KEGG pathways for AMPD1 Gene
2 GeneGo (Thomson Reuters) pathways for AMPD1 Gene
UniProtKB/Swiss-Prot P23109-AMPD1_HUMAN
- Pathway: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.
Interacting Proteins for AMPD1 Gene
Selected Interacting proteins:
ENSP00000430075
P23109-AMPD1_HUMAN
for AMPD1 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0009117 | nucleotide metabolic process | IEA | -- |
| GO:0009168 | purine ribonucleoside monophosphate biosynthetic process | IEA | -- |
| GO:0010033 | response to organic substance | IEA | -- |
| GO:0032264 | IMP salvage | IEA | -- |
| GO:0043101 | purine-containing compound salvage | TAS | -- |
No data available for SIGNOR curated interactions for AMPD1 Gene
Drugs & Compounds for AMPD1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Adenosine monophosphate | Approved | Nutra | Enzyme, substrate | 0 | ||
| Methotrexate | Approved | Pharma | Folate antagonist,inhibits DFHR | 1551 | ||
| Regadenoson | Approved | Pharma | Agonist | Highly selective and low affinity A2A adenosine agonist | 70 | |
| Cladribine | Approved, Investigational | Pharma | Apoptosis inducer in CLL cells | 73 | ||
| Propranolol | Approved, Investigational | Pharma | Antagonist | Beta blocker | 228 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Ammonia |
|
7664-41-7 |
|
(1) ApexBio Compounds for AMPD1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Cladribine | Apoptosis inducer in CLL cells | 4291-63-8 |
Transcripts for AMPD1 Gene
mRNA/cDNA for AMPD1 Gene
- (2) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (358) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for AMPD1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for AMPD1
-
Applied Biological Materials CRISPR for AMPD1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPD1
- GenScript: Design CRISPR guide RNA sequences for AMPD1
miRNA Products
- Search ViGene Biosciences for AMPD1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for AMPD1
- Browse OriGene Inhibitory RNA Products For AMPD1
-
ViGene Biosciences ready-to-package AAV shRNAs for AMPD1 gene
Clone Products
- Sino Biological Human cDNA Clone for AMPD1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AMPD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for AMPD1 Gene
mRNA differential expression in normal tissues according to GTEx for AMPD1 Gene
This gene is overexpressed in Muscle - Skeletal (x49.7).
This gene is overexpressed in Cervix (37.1) and Tonsil (31.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for AMPD1 Gene
NURSA nuclear receptor signaling pathways regulating expression of AMPD1 Gene:
AMPD1SOURCE GeneReport for Unigene cluster for AMPD1 Gene:
Hs.89570Evidence on tissue expression from TISSUES for AMPD1 Gene
- Muscle(3.8)
- Heart(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for AMPD1 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- nervous
- skeletal muscle
Organs:
Head and neck:
- brain
General:
- peripheral nerve
- peripheral nervous system
- spinal cord
Primer Products
-
OriGene qPCR primer pairs for AMPD1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for AMPD1 Gene
Orthologs for AMPD1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AMPD1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | AMPD1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | AMPD1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ampd1 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | AMPD1 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Ampd1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AMPD1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | AMPD1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | AMPD1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ampd1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ampd1 34 35 |
|
||
| -- 34 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | C34F11.3b 36 |
|
|
|
| C34F11.3a 36 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AMD1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for AMPD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for AMPD1 Gene
(2) SIMAP similar genes for AMPD1 Gene using alignment to 11 proteins:
Variants for AMPD1 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121912682 | Pathogenic, Myopathy due to myoadenylate deaminase deficiency (MMDD) [MIM:615511] | 114,677,465(-) | GCCCC(A/G)CCTGT | reference, missense | |
| rs35859650 | Pathogenic, Myopathy due to myoadenylate deaminase deficiency (MMDD) [MIM:615511] | 114,677,972(+) | GTCCC(A/G)TAGCT | reference, missense | |
| VAR_035801 | A colorectal cancer sample | ||||
| rs17602729 | Pathogenic | 114,693,436(-) | AGAAA(A/C/T)GTGAG | intron-variant, reference, missense, stop-gained | |
| rs34526199 | Pathogenic | 114,679,616(+) | TGTTT(A/T)TCAGC | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv28734 | CNV | loss | 19812545 |
| esv3587269 | CNV | loss | 21293372 |
| esv3587274 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
52.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.23;
76.17% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AMPD1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMPD1 Gene
Disorders for AMPD1 Gene
(8) MalaCards diseases for AMPD1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myopathy due to myoadenylate deaminase deficiency |
|
|
| adenosine monophosphate deaminase 1 deficiency |
|
|
| mcardle disease |
|
|
| myopathy |
|
|
| myoglobinuria |
|
|
Search AMPD1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
AMPD1_HUMAN- Myopathy due to myoadenylate deaminase deficiency (MMDD) [MIM:615511]: A metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue. {ECO:0000269 PubMed:11102975}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Genatlas disease for AMPD1 Gene
myopathy,exercise-related
Relevant External Links for AMPD1
Publications for AMPD1 Gene
- Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing. (PMID: 19422651) Santiago C. … Lucia A. (Scand J Med Sci Sports 2010) 3 22 46 64
- Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners. (PMID: 20044476) Tsianos G.I. … Ioannidis J.P. (J. Appl. Physiol. 2010) 3 22 46 64
- Association of C34T AMPD1 gene polymorphism with features of metabolic syndrome in patients with coronary artery disease or heart failure. (PMID: 18855224) Safranow K. … Chlubek D. (Scand. J. Clin. Lab. Invest. 2009) 3 22 46 64
- Myoadenylate deaminase deficiency: clinico-pathological and molecular study of a series of 27 Spanish cases. (PMID: 19353846) Teijeira S. … Navarro C. (Clin. Neuropathol. 2009) 3 22 46 64
- Effect of adenosine monophosphate deaminase-1 C34T allele on the requirement for donor inotropic support and on the incidence of early graft dysfunction after cardiac transplantation. (PMID: 19427446) Taegtmeyer A.B. … Barton P.J. (Am. J. Cardiol. 2009) 3 22 46 64
Products for AMPD1 Gene
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for AMPD1
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- antibodies-online Antibodies for AMPD1: See all 68
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- antibodies-online Proteins for AMPD1: See all 6
- Search antibodies-online for peptides
- GeneTex AMPD1 antibody for AMPD1
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- ViGene Biosciences adenoviral particle packaged cDNA for AMPD1 gene
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- Search ViGene Biosciences for AMPD1
- Santa Cruz Biotechnology (SCBT) Antibodies for AMPD1
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- Santa Cruz Biotechnology (SCBT) CRISPR for AMPD1
- Horizon Cell Lines for AMPD1
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMPD1
- VectorBuilder custom plasmid, inducible vectors for AMPD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPD1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AMPD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
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