AMOTL2 Gene
protein-coding GIFtS: 52
GCID: GC03M134074
|
|
angiomotin like 2
| |
Aliases
for AMOTL2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Angiomotin Like 21 2 | | LCCP1 2 3 | | Leman Coiled-Coil Protein2 3 | | Angiomotin-Like Protein 22 | | KIAA09893 |
Export aliases for AMOTL2 gene to outside databasesPrevious GC identifers: GC03M131013 GC03M134860 GC03M135356 GC03M135395 GC03M135556 GC03M131452 |
Summaries
for AMOTL2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AMOTL2:
Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels(angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro.The protein encoded by this gene is related to angiomotin and is a member of the motins protein family. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: AMOL2_HUMAN, Q9Y2J4Function: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required forproper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play arole in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPKactivation through SRC
Gene Wiki entry for AMOTL2
|
Genomic Views
for AMOTL2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AMOTL2 gene promoter:
Max1 RFX1 SREBP-1c IRF-1 SREBP-1b FAC1 SREBP-1a FOXO4 c-Myb c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for AMOTL2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMOTL2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q21-q22 Ensembl cytogenetic band: 3q22.2 HGNC cytogenetic band: 3q21-q22AMOTL2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M134074: view genomic region
(about GC identifiers)
Start:
|
134,074,190 bp from pter |
End:
|
134,094,321 bp from pter |
Size:
|
20,132 bases |
Orientation:
|
minus strand |
|
Proteins
for AMOTL2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AMOL2_HUMAN, Q9Y2J4 (See
protein sequence)Recommended Name: Angiomotin-like protein 2 Size: 779 amino acids; 85764 Da
Subunit: Interacts with SRC
Subcellular location: Recycling endosome (By similarity)
Sequence caution: Sequence=AAH11454.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA76833.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAD97318.1;Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K6F1 B7Z5Q1 E9PHW3 Q53EP1 Q96F99 Q9UKB4Alternative splicing: 4 isoforms: Q9Y2J4-1 Q9Y2J4-2 Q9Y2J4-3 Q9Y2J4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for AMOTL2: NX_Q9Y2J4
Post-translational modifications:
Phosphorylation at Tyr-107 is necessary for efficient binding to SRC and synergistically functioning with SRC toactivate the downstream MAPK pathway (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2J4
AMOTL2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057285.3
ENSEMBL proteins: ENSP00000249883 ENSP00000409999 ENSP00000424765 ENSP00000425475 ENSP00000427184 ENSP00000424910 ENSP00000427292 ENSP00000422658 ENSP00000427482 ENSP00000421521 Reactome Protein details: Q9Y2J4
Human Recombinant Protein Products for AMOTL2:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
AMOTL2 for ontologies About GeneDecksing
AMOTL2 Antibody Products:
Assay Products for AMOTL2: |
Protein
Domains /
Families
for AMOTL2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AMOTL2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y2J4ProtoNet protein and cluster: Q9Y2J4 UniProtKB/Swiss-Prot: AMOL2_HUMAN, Q9Y2J4Similarity: Belongs to the angiomotin family |
Function
for AMOTL2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: AMOL2_HUMAN, Q9Y2J4Function: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required forproper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play arole in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPKactivation through SRC Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0042802 | identical protein binding |
IEA | -- |
AMOTL2 for ontologies About GeneDecksing
Animal Models:
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AMOTL2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: AMOTL2 (NM_016201) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AMOTL2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AMOTL2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMOTL2 |
|
Pathways & Interactions
for AMOTL2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by Hippo | | | 2 | Signaling by GPCR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for AMOTL2
AMOTL2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AMOTL2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
5/28 Interacting proteins for AMOTL2 (Q9Y2J42, 3 ENSP000002498834) via UniProtKB, MINT, STRING, and/or I2D (see all 28)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016055 | Wnt receptor signaling pathway |
IEA | -- | | GO:0035329 | hippo signaling cascade |
TAS | -- |
AMOTL2 for ontologies About GeneDecksing
|
Drugs & Compounds
for AMOTL2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AMOTL2
Search CenterWatch for drugs/clinical trials and news about AMOTL2 / AMOL2
|
Transcripts
for AMOTL2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AMOTL2 gene: NM_016201.2 Unigene Cluster for AMOTL2: Angiomotin like 2 Hs.426312 [show with all ESTs]Unigene Representative Sequence: NM_01620113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000249883(uc003eqg.1 uc003eqh.1) ENST00000422605 ENST00000514516(uc003eqf.2)
ENST00000506326(uc003eqe.1) ENST00000513145 ENST00000512955 ENST00000511759
ENST00000510560 ENST00000504234 ENST00000505596 ENST00000506107 ENST00000515172
ENST00000502491
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AMOTL2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AMOTL2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: AMOTL2 (NM_016201) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AMOTL2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AMOTL2 |
Additional cDNA sequence: AB023206.1 AF175966.1 AK001343.1 AK074731.1 AK223598.1 AK291616.1 AK299270.1 BC011454.1 BC025981.2 12 DOTS entries: DT.447894 DT.100819952 DT.120914998 DT.120915014 DT.75165614 DT.120915029 DT.120915027 DT.99938361 DT.100819949 DT.102824642 DT.120914994 DT.40235770 24/214 AceView cDNA sequences (see all 214): T59967 BC011454 BQ183597 CB961574 CD514256 AA341416 AI214560 AK001343 CA412700 CR614830 AI299504 AW104853 AU124500 AA897220 AA341373 NM_016201 BQ448483 BU682537 AI561222 BF222982 CB960406 BQ008752 BF059703 CB988092
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for AMOTL2 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP5: | | | | | | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | |
| ExUns: | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c |
|---|
|
| SP1: | | | - | | | | | | | | |
| SP2: | | | - | | | | | | | | |
| SP3: | | | - | | | | | | | | |
| SP4: | | | - | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for AMOTL2
|
Expression
for AMOTL2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AMOTL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGTTTTGT
About this image
See AMOTL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AMOTL2
SOURCE GeneReport for Unigene cluster: Hs.426312
SABiosciences Custom PCR Arrays for AMOTL2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AMOTL2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AMOTL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AMOTL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AMOTL2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMOTL2 |
Orthologs
for AMOTL2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for AMOTL2 gene from 6/14 species (see all 14) About this table
ENSEMBL Gene Tree for AMOTL2 (if available)
TreeFam Gene Tree for AMOTL2 (if available) |
Paralogs
for AMOTL2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AMOTL2 gene
- AMOTL12 AMOT2
2 SIMAP similar genes for AMOTL2 using alignment to 7 protein entries: AMOL2_HUMAN (see all proteins):AMOT AMOTL1
AMOTL2 for paralogs About GeneDecksing
|
Genomic Variants
for AMOTL2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AMOTL2 (134074190 - 134094321 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AMOTL2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AMOTL2 |
|
Disorders
/ Diseases
for AMOTL2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 AMOTL2 for disorders About MalaCards
AMOTL2 for disorders About GeneDecksing
OMIM gene information: 614658
OMIM disorders: --
Export disorders for AMOTL2 gene to outside databases
|
Publications
for AMOTL2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AMOTL2 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with AMOTL2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Angiomotin belongs to a novel protein family with conserved coiled- coil and PDZ binding domains. (PubMed id 12406577)1, 2, 9 Bratt A.... Holmgren L. (2002)
- Angiomotin-like2 gene (amotl2) is required for migrat ion and proliferation of endothelial cells during angiogenesis. (PubMed id 21937427)1, 2 Wang Y....Meng A. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
- A yeast two-hybrid screen reveals that osteopontin ass ociates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (2012)
- The Amotl2 gene inhibits Wnt/beta-catenin signaling and regulates embryonic development in zebrafish. (PubMed id 22362771)2 Li Z.... Meng A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Angiomotin family proteins are novel activators of th e LATS2 kinase tumor suppressor. (PubMed id 21832154)1 Paramasivam M....McCollum D. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
|
External Searches for AMOTL2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AMOTL2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AMOTL2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing AMOTL2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AMOTL2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AMOTL2 gene:
Search GeneIP for patents involving AMOTL2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AMOTL2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for AMOTL2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AMOTL2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AMOTL2 | | | OriGene Protein Over-expression Lysate for AMOTL2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AMOTL2 | | OriGene 3'-UTR Clone for AMOTL2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AMOTL2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AMOTL2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AMOTL2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AMOTL2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMOTL2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AMOTL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AMOTL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AMOTL2 |
| |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMOTL2 |
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