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Aliases for AMN1 Gene

Aliases for AMN1 Gene

  • Antagonist Of Mitotic Exit Network 1 Homolog (S. Cerevisiae) 2 3

External Ids for AMN1 Gene

Previous GeneCards Identifiers for AMN1 Gene

  • GC12M031716
  • GC12M031824
  • GC12M031576

Summaries for AMN1 Gene

GeneCards Summary for AMN1 Gene

AMN1 (Antagonist Of Mitotic Exit Network 1 Homolog (S. Cerevisiae)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMN1 Gene

Genomics for AMN1 Gene

Regulatory Elements for AMN1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for AMN1 Gene

Start:
31,671,137 bp from pter
End:
31,729,174 bp from pter
Size:
58,038 bases
Orientation:
Minus strand

Genomic View for AMN1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AMN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AMN1 Gene

Proteins for AMN1 Gene

  • Protein details for AMN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IY45-AMN1_HUMAN
    Recommended name:
    Protein AMN1 homolog
    Protein Accession:
    Q8IY45
    Secondary Accessions:
    • B7Z7J3
    • Q6NVU4
    • Q86X98

    Protein attributes for AMN1 Gene

    Size:
    258 amino acids
    Molecular mass:
    28408 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH37897.3; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH45831.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH67906.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for AMN1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AMN1 Gene

Proteomics data for AMN1 Gene at MOPED

Post-translational modifications for AMN1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for AMN1 Gene

Domains for AMN1 Gene

Protein Domains for AMN1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for AMN1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IY45

UniProtKB/Swiss-Prot:

AMN1_HUMAN :
  • Q8IY45
Family:
  • Belongs to the AMN1 family.
genes like me logo Genes that share domains with AMN1: view

No data available for Gene Families for AMN1 Gene

Function for AMN1 Gene

Phenotypes for AMN1 Gene

GenomeRNAi human phenotypes for AMN1:
genes like me logo Genes that share phenotypes with AMN1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AMN1 Gene

Localization for AMN1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for AMN1 Gene COMPARTMENTS Subcellular localization image for AMN1 gene
Compartment Confidence
extracellular 2
cytosol 1
lysosome 1
mitochondrion 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for AMN1 Gene

Pathways for AMN1 Gene

SuperPathways for AMN1 Gene

No Data Available

Interacting Proteins for AMN1 Gene

Gene Ontology (GO) - Biological Process for AMN1 Gene

None

No data available for Pathways by source for AMN1 Gene

Transcripts for AMN1 Gene

Unigene Clusters for AMN1 Gene

Antagonist of mitotic exit network 1 homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for AMN1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for AMN1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for AMN1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c · 10d ^ 11
SP1: -
SP2: - - - -
SP3: - - - - -
SP4: - - - - -
SP5: - -
SP6:
SP7: - - -

Relevant External Links for AMN1 Gene

GeneLoc Exon Structure for
AMN1
ECgene alternative splicing isoforms for
AMN1

Expression for AMN1 Gene

mRNA expression in normal human tissues for AMN1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for AMN1 Gene

SOURCE GeneReport for Unigene cluster for AMN1 Gene Hs.585084

genes like me logo Genes that share expressions with AMN1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for AMN1 Gene

Orthologs for AMN1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for AMN1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AMN1 35
  • 99.61 (n)
  • 99.61 (a)
AMN1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia AMN1 35
  • 90.96 (n)
  • 91.47 (a)
AMN1 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AMN1 35
  • 91.09 (n)
  • 91.47 (a)
AMN1 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Amn1 35
  • 82.17 (n)
  • 76.36 (a)
Amn1 16
Amn1 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia AMN1 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia AMN1 36
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Amn1 35
  • 83.2 (n)
  • 79.84 (a)
chicken
(Gallus gallus)
Aves AMN1 35
  • 70.37 (n)
  • 68.25 (a)
AMN1 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia AMN1 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485350 35
  • 59.67 (n)
  • 60 (a)
zebrafish
(Danio rerio)
Actinopterygii amn1 35
  • 55.56 (n)
  • 47.56 (a)
amn1 36
  • 47 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes AMN1 38
Species with no ortholog for AMN1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for AMN1 Gene

ENSEMBL:
Gene Tree for AMN1 (if available)
TreeFam:
Gene Tree for AMN1 (if available)

Paralogs for AMN1 Gene

genes like me logo Genes that share paralogs with AMN1: view

No data available for Paralogs for AMN1 Gene

Variants for AMN1 Gene

Sequence variations from dbSNP and Humsavar for AMN1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs3534 -- 31,671,319(+) ATGGA(A/G)TTGAA utr-variant-3-prime, nc-transcript-variant, downstream-variant-500B
rs12698 -- 31,671,510(+) AGTTT(C/T)CACTT utr-variant-3-prime, nc-transcript-variant, downstream-variant-500B
rs874038 -- 31,721,831(+) aatgg(C/T)tcatt intron-variant
rs1021165 -- 31,725,430(-) AACTA(A/T)TATTG intron-variant
rs1021166 -- 31,725,341(-) GTCTT(A/G)AGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AMN1 Gene

Variant ID Type Subtype PubMed ID
nsv662 CNV Insertion 18451855
nsv898966 CNV Gain 21882294
esv2667845 CNV Deletion 23128226
nsv898967 CNV Loss 21882294
esv2422415 CNV Duplication 17116639

Relevant External Links for AMN1 Gene

HapMap Linkage Disequilibrium report
AMN1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMN1 Gene

Disorders for AMN1 Gene

No disorders were found for AMN1 Gene.

No data available for UniProtKB/Swiss-Prot for AMN1 Gene

Publications for AMN1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. (PMID: 23761726) Yazar S. … Hewitt A.W. (Mol. Vis. 2013) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for AMN1 Gene

Sources for AMN1 Gene

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