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Aliases for AMMECR1L Gene

Aliases for AMMECR1L Gene

  • AMMECR1 Like 2 3 5
  • AMME Chromosomal Region Gene 1-Like 2
  • AMMECR1-Like 2

External Ids for AMMECR1L Gene

Previous GeneCards Identifiers for AMMECR1L Gene

  • GC02M128336
  • GC02M128619
  • GC02M120925

Summaries for AMMECR1L Gene

GeneCards Summary for AMMECR1L Gene

AMMECR1L (AMMECR1 Like) is a Protein Coding gene. An important paralog of this gene is AMMECR1.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMMECR1L Gene

Genomics for AMMECR1L Gene

Regulatory Elements for AMMECR1L Gene

Enhancers for AMMECR1L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G127012 0.9 ENCODE 42.3 +875.6 875591 0.8 HDGF ZFP64 BMI1 PLRG1 ZNF48 ZNF354C KLF7 ZNF202 ZNF654 ZBTB11 AMMECR1L ERCC3 WDR33 ENSG00000260634 ENSG00000231731 RNU7-182P TEX51
GH02G127770 1.1 Ensembl ENCODE 29.1 +116.9 116890 2.0 ATF1 ZFP64 ZNF138 GATA2 ZNF354C KLF7 FOS ZNF202 ZNF654 CEBPB AMMECR1L ERCC3 ENSG00000260634 POLR2D PIR38298 GC02M127799 RNY4P7
GH02G127099 1.6 Ensembl ENCODE dbSUPER 18.3 +784.3 784330 8.6 FOXA2 PKNOX1 CREB3L1 MLX AGO1 ZFP64 ARID4B SIN3A DMAP1 FEZF1 AMMECR1L WDR33 BIN1 ERCC3 ENSG00000260634
GH02G128321 1.5 Ensembl ENCODE dbSUPER 17 -433.7 -433720 2.2 ATF1 ARID4B SIN3A DMAP1 ZNF48 GTF3C2 ZNF143 ZNF207 KLF13 SP3 AMMECR1L WDR33 UGGT1 HS6ST1 GC02M128305
GH02G128090 1.1 ENCODE 21.9 -202.8 -202811 1.9 HDGF CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 AMMECR1L UGGT1 SAP130 WDR33 GC02P128122
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AMMECR1L on UCSC Golden Path with GeneCards custom track

Genomic Location for AMMECR1L Gene

Chromosome:
2
Start:
127,861,630 bp from pter
End:
127,888,570 bp from pter
Size:
26,941 bases
Orientation:
Minus strand

Genomic View for AMMECR1L Gene

Genes around AMMECR1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AMMECR1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AMMECR1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AMMECR1L Gene

Proteins for AMMECR1L Gene

  • Protein details for AMMECR1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6DCA0-AMERL_HUMAN
    Recommended name:
    AMMECR1-like protein
    Protein Accession:
    Q6DCA0
    Secondary Accessions:
    • B4E276

    Protein attributes for AMMECR1L Gene

    Size:
    310 amino acids
    Molecular mass:
    34499 Da
    Quaternary structure:
    No Data Available

neXtProt entry for AMMECR1L Gene

Post-translational modifications for AMMECR1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for AMMECR1L Gene

Domains & Families for AMMECR1L Gene

Protein Domains for AMMECR1L Gene

Suggested Antigen Peptide Sequences for AMMECR1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AMMECR1L: view

No data available for Gene Families and UniProtKB/Swiss-Prot for AMMECR1L Gene

Function for AMMECR1L Gene

genes like me logo Genes that share phenotypes with AMMECR1L: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AMMECR1L Gene

Localization for AMMECR1L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for AMMECR1L gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for AMMECR1L Gene

Pathways & Interactions for AMMECR1L Gene

SuperPathways for AMMECR1L Gene

No Data Available

Gene Ontology (GO) - Biological Process for AMMECR1L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AMMECR1L Gene

Drugs & Compounds for AMMECR1L Gene

No Compound Related Data Available

Transcripts for AMMECR1L Gene

Unigene Clusters for AMMECR1L Gene

AMMECR1-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for AMMECR1L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
SP1: - -
SP2: -
SP3:
SP4: -

Relevant External Links for AMMECR1L Gene

GeneLoc Exon Structure for
AMMECR1L
ECgene alternative splicing isoforms for
AMMECR1L

Expression for AMMECR1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AMMECR1L Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for AMMECR1L Gene



NURSA nuclear receptor signaling pathways regulating expression of AMMECR1L Gene:

AMMECR1L

SOURCE GeneReport for Unigene cluster for AMMECR1L Gene:

Hs.546449
genes like me logo Genes that share expression patterns with AMMECR1L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AMMECR1L Gene

Orthologs for AMMECR1L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for AMMECR1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AMMECR1L 34 35
  • 100 (n)
oppossum
(Monodelphis domestica)
Mammalia AMMECR1L 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AMMECR1L 34 35
  • 97.53 (n)
cow
(Bos Taurus)
Mammalia AMMECR1L 34 35
  • 95.59 (n)
rat
(Rattus norvegicus)
Mammalia Ammecr1l 34
  • 94.95 (n)
mouse
(Mus musculus)
Mammalia Ammecr1l 34 16 35
  • 94.3 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia AMMECR1L 35
  • 91 (a)
OneToOne
chicken
(Gallus gallus)
Aves AMMECR1L 34 35
  • 88.39 (n)
lizard
(Anolis carolinensis)
Reptilia AMMECR1L 35
  • 95 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ammecr1l 34
  • 74.34 (n)
zebrafish
(Danio rerio)
Actinopterygii Dr.13202 34
fruit fly
(Drosophila melanogaster)
Insecta CG5902 35
  • 55 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea R166.3 35
  • 43 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 35
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9118 35
  • 45 (a)
OneToMany
Species where no ortholog for AMMECR1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for AMMECR1L Gene

ENSEMBL:
Gene Tree for AMMECR1L (if available)
TreeFam:
Gene Tree for AMMECR1L (if available)

Paralogs for AMMECR1L Gene

Paralogs for AMMECR1L Gene

(1) SIMAP similar genes for AMMECR1L Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for AMMECR1L Gene

genes like me logo Genes that share paralogs with AMMECR1L: view

Variants for AMMECR1L Gene

Sequence variations from dbSNP and Humsavar for AMMECR1L Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000280971 -- 127,861,841(+) CTCAA(C/T)AGAAA intron-variant, utr-variant-3-prime
rs1000442092 -- 127,862,101(+) GATCA(A/C)AGACA intron-variant, utr-variant-3-prime
rs1000691840 -- 127,867,714(+) GCACT(A/C)CAGCC intron-variant
rs1000697803 -- 127,879,140(+) CAAAA(A/T)GCAAA intron-variant
rs1000769841 -- 127,879,351(+) AAAAG(G/T)GTGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AMMECR1L Gene

Variant ID Type Subtype PubMed ID
esv3303901 CNV mobile element insertion 20981092
esv3308379 CNV mobile element insertion 20981092
esv3373656 CNV insertion 20981092
esv3393135 CNV duplication 20981092
esv3448130 CNV insertion 20981092
nsv1133485 CNV deletion 24896259
nsv834367 CNV loss 17160897

Variation tolerance for AMMECR1L Gene

Residual Variation Intolerance Score: 63.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.04; 21.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AMMECR1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AMMECR1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMMECR1L Gene

Disorders for AMMECR1L Gene

Relevant External Links for AMMECR1L

Genetic Association Database (GAD)
AMMECR1L
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AMMECR1L

No disorders were found for AMMECR1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AMMECR1L Gene

Publications for AMMECR1L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3 64
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64

Products for AMMECR1L Gene

Sources for AMMECR1L Gene

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