Aliases for AMMECR1L Gene
External Ids for AMMECR1L Gene
- HGNC: 28658
- Entrez Gene: 83607
- Ensembl: ENSG00000144233
- UniProtKB: Q6DCA0
Previous GeneCards Identifiers for AMMECR1L Gene
- GC02M128336
- GC02M128619
- GC02M120925
Summaries for AMMECR1L Gene
GeneCards Summary for AMMECR1L Gene
AMMECR1L (AMMECR1 Like) is a Protein Coding gene. An important paralog of this gene is AMMECR1.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMMECR1L Gene
Genomics for AMMECR1L Gene
Regulatory Elements for AMMECR1L Gene
Enhancers for AMMECR1L Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AMMECR1L on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the AMMECR1L gene promoter:
Regulatory Element Products
Genomic Location for AMMECR1L Gene
- Chromosome:
- 2
- Start:
- 127,861,630 bp from pter
- End:
- 127,888,570 bp from pter
- Size:
- 26,941 bases
- Orientation:
- Minus strand
Genomic View for AMMECR1L Gene
Genes around AMMECR1L on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q14.3 by Ensembl
- 2q14.3 by Entrez Gene
- 2q14.3 by HGNC
AMMECR1L Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AMMECR1L Gene
Proteins for AMMECR1L Gene
-
Protein details for AMMECR1L Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6DCA0-AMERL_HUMAN
- Recommended name:
- AMMECR1-like protein
- Protein Accession:
- Q6DCA0
- B4E276
Protein attributes for AMMECR1L Gene
- Size:
- 310 amino acids
- Molecular mass:
- 34499 Da
- Quaternary structure:
- No Data Available
Protein Expression for AMMECR1L Gene
Post-translational modifications for AMMECR1L Gene
Other Protein References for AMMECR1L Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for AMMECR1L
- Novus Biologicals Antibodies for AMMECR1L
- Invitrogen Antibodies for AMMECR1L
- Search GeneTex for Antibodies for AMMECR1L
Protein Products
-
OriGene Purified Proteins for AMMECR1L
- Search Origene for MassSpec and Protein Over-expression Lysates for AMMECR1L
- Origene Custom Protein Services for AMMECR1L
- Novus Biologicals proteins for AMMECR1L
- ProSpec Recombinant Proteins for AMMECR1L
- Search GeneTex for Proteins for AMMECR1L
Assay Products
No data available for DME Specific Peptides for AMMECR1L Gene
Domains & Families for AMMECR1L Gene
Protein Domains for AMMECR1L Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for AMMECR1L Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for AMMECR1L Gene
Function for AMMECR1L Gene
Phenotypes for AMMECR1L Gene
- GenomeRNAi human phenotypes for AMMECR1L:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Increased G1 DNA content
- G0/1 arrest
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after direct virus infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMMECR1L
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AMMECR1L gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMMECR1L gene
- Search ViGene Biosciences for AMMECR1L
CRISPR Products
-
OriGene CRISPR knockouts for AMMECR1L
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMMECR1L
- GenScript: Design CRISPR guide RNA sequences for AMMECR1L
miRNA for AMMECR1L Gene
- miRTarBase miRNAs that target AMMECR1L
-
- hsa-mir-101-3p (MIRT027316)
- hsa-mir-877-3p (MIRT036891)
- hsa-mir-484 (MIRT041681)
- hsa-mir-423-3p (MIRT042613)
- hsa-mir-15b-5p (MIRT046528)
- hsa-mir-221-3p (MIRT046855)
- hsa-mir-10a-5p (MIRT047569)
- hsa-mir-19a-3p (MIRT203045)
- hsa-mir-19b-3p (MIRT203046)
- hsa-mir-548aw (MIRT203062)
- hsa-mir-4446-5p (MIRT649216)
- hsa-mir-3679-3p (MIRT649217)
- hsa-mir-2355-5p (MIRT649218)
- hsa-mir-29a-5p (MIRT649219)
- hsa-mir-1468-3p (MIRT705720)
- hsa-mir-548x-5p (MIRT705721)
- hsa-mir-548g-5p (MIRT705722)
- hsa-mir-548f-5p (MIRT705723)
- hsa-mir-548aj-5p (MIRT705724)
- hsa-mir-6505-3p (MIRT705725)
- hsa-mir-581 (MIRT705726)
- hsa-mir-6840-3p (MIRT705727)
- hsa-mir-500b-3p (MIRT705728)
- hsa-mir-8083 (MIRT705729)
- hsa-mir-7161-3p (MIRT705730)
- hsa-mir-3591-3p (MIRT705731)
- hsa-mir-21-3p (MIRT705732)
miRNA Products
- Search ViGene Biosciences for AMMECR1L
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AMMECR1L
- Browse OriGene Inhibitory RNA Products For AMMECR1L
-
ViGene Biosciences ready-to-package AAV shRNAs for AMMECR1L gene
Clone Products
-
OriGene ORF clones in human for AMMECR1L
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AMMECR1L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMMECR1L
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for AMMECR1L
-
ViGene Biosciences adenoviral particle packaged cDNA for AMMECR1L gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AMMECR1L gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AMMECR1L gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AMMECR1L Gene
Localization for AMMECR1L Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| extracellular | 1 |
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for AMMECR1L Gene
Pathways & Interactions for AMMECR1L Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for AMMECR1L Gene
Transcripts for AMMECR1L Gene
mRNA/cDNA for AMMECR1L Gene
- (10) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (142) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for AMMECR1L
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMMECR1L
- GenScript: Design CRISPR guide RNA sequences for AMMECR1L
miRNA Products
- Search ViGene Biosciences for AMMECR1L
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AMMECR1L
- Browse OriGene Inhibitory RNA Products For AMMECR1L
-
ViGene Biosciences ready-to-package AAV shRNAs for AMMECR1L gene
Clone Products
-
OriGene ORF clones in human for AMMECR1L
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AMMECR1L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMMECR1L
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||
| SP4: | - |
Expression for AMMECR1L Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for AMMECR1L Gene
NURSA nuclear receptor signaling pathways regulating expression of AMMECR1L Gene:
AMMECR1LSOURCE GeneReport for Unigene cluster for AMMECR1L Gene:
Hs.546449Primer Products
-
OriGene qPCR primer pairs for AMMECR1L
-
OriGene qPCR primer pairs and template standards for AMMECR1L
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AMMECR1L Gene
Orthologs for AMMECR1L Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AMMECR1L 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AMMECR1L 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | AMMECR1L 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | AMMECR1L 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ammecr1l 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ammecr1l 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | AMMECR1L 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | AMMECR1L 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | AMMECR1L 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ammecr1l 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | Dr.13202 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5902 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | R166.3 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | -- 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.9118 35 |
|
OneToMany |
- Species where no ortholog for AMMECR1L was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for AMMECR1L Gene
(1) SIMAP similar genes for AMMECR1L Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for AMMECR1L Gene
Variants for AMMECR1L Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000280971 | -- | 127,861,841(+) | CTCAA(C/T)AGAAA | intron-variant, utr-variant-3-prime | |
| rs1000442092 | -- | 127,862,101(+) | GATCA(A/C)AGACA | intron-variant, utr-variant-3-prime | |
| rs1000691840 | -- | 127,867,714(+) | GCACT(A/C)CAGCC | intron-variant | |
| rs1000697803 | -- | 127,879,140(+) | CAAAA(A/T)GCAAA | intron-variant | |
| rs1000769841 | -- | 127,879,351(+) | AAAAG(G/T)GTGTG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3303901 | CNV | mobile element insertion | 20981092 |
| esv3308379 | CNV | mobile element insertion | 20981092 |
| esv3373656 | CNV | insertion | 20981092 |
| esv3393135 | CNV | duplication | 20981092 |
| esv3448130 | CNV | insertion | 20981092 |
| nsv1133485 | CNV | deletion | 24896259 |
| nsv834367 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
63.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.04;
21.31% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AMMECR1L Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AMMECR1L
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMMECR1L Gene
Disorders for AMMECR1L Gene
Relevant External Links for AMMECR1L
No disorders were found for AMMECR1L Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AMMECR1L Gene
Publications for AMMECR1L Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3 64
- Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
Products for AMMECR1L Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Custom Antibody ServicesOriGene Antibodies for AMMECR1L
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- Browse OriGene Inhibitory RNA Products For AMMECR1L
- OriGene qPCR primer pairs and template standards for AMMECR1L
- OriGene qPCR primer pairs for AMMECR1L
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- GenScript: Next-day shipping cDNA ORF clone for AMMECR1L in any vector
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- Novus Biologicals Antibodies for AMMECR1L
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- ProSpec Recombinant Proteins for AMMECR1L
- ViGene Biosciences adenoviral particle packaged cDNA for AMMECR1L gene
- ViGene Biosciences lentiviral particle packaged cDNA for AMMECR1L gene
- ViGene Biosciences ready-to-package AAV shRNAs for AMMECR1L gene
- Search ViGene Biosciences for AMMECR1L
- Horizon Cell Lines for AMMECR1L
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMMECR1L
- VectorBuilder custom plasmid, inducible vectors for AMMECR1L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMMECR1L
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AMMECR1L Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
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- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer