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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

AMMECR1 Gene

protein-coding GIFtS: 54
GCID: GC0XM109437

Alport syndrome, mental retardation, midface hypoplasia...

Explore 5 diseases affiliated with
AMMECR1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Alport Syndrome, Mental Retardation, Midface Hypoplasia And Elliptocytosis Chromosomal Region Gene 1¹ ²
AMMERC1²
AMME Syndrome Candidate Gene 1 Protein²

External Ids:	HGNC: 467¹	Entrez Gene: 9949²	Ensembl: ENSG00000101935⁷	OMIM: 300195⁵	UniProtKB: Q9Y4X0³

Export aliases for AMMECR1 gene to outside databases

Previous GC identifers: GC0XM104744 GC0XM106586 GC0XM107464 GC0XM108205 GC0XM108203 GC0XM109247 GC0XM099058

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AMMECR1:

The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene,

COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental

retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different

isoforms have been found for this gene. (provided by RefSeq, Jan 2010)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000023.10 NC_018934.1 NT_011651.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the AMMECR1 gene promoter:
STAT5B Pbx1a GATA-3 GCNF AP-4 RelA Egr-4 FAC1 GCNF-1 GCNF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: AMMECR1 promoter sequence

Search SABiosciences Chromatin IP Primers for AMMECR1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMMECR1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.3 Ensembl cytogenetic band: Xq23 HGNC cytogenetic band: Xq22.3

AMMECR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMMECR1 gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XM109437: view genomic region (about GC identifiers)

Start:	109,437,414 bp from pter	End:	109,683,461 bp from pter
Size:	246,048 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AMMR1_HUMAN, Q9Y4X0 (See protein sequence)

Recommended Name: AMME syndrome candidate gene 1 protein

Size: 333 amino acids; 35463 Da

Secondary accessions: Q5JYV9 Q6P9D8 Q8WX22 Q9UIQ8

Alternative splicing: 4 isoforms: Q9Y4X0-1 Q9Y4X0-2 Q9Y4X0-3 Q9Y4X0-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AMMECR1: NX_Q9Y4X0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y4X0

AMMECR1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001020751.1 NP_001165160.1 NP_056180.1

ENSEMBL proteins:

ENSP00000262844 ENSP00000361129 ENSP00000361127

Human Recombinant Protein Products:

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	Uscn Proteins for AMMECR1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--

AMMECR1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for AMMECR1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

AMMECR1 for domains About GeneDecksing

2 InterPro domains/families:

IPR023473 AMMECR1

IPR002733 AMMECR1_domain

Graphical View of Domain Structure for InterPro Entry Q9Y4X0

ProtoNet protein and cluster: Q9Y4X0

UniProtKB/Swiss-Prot: AMMR1_HUMAN, Q9Y4X0

Similarity: Contains 1 AMMECR1 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

Genatlas biochemistry entry for AMMECR1:

highly conserved nuclear protein deleted in the AMME contiguous gene syndrome

miRNA Products:		miRTarBase miRNAs that target AMMECR1: hsa-let-7a (MIRT004965), hsa-mir-98 (MIRT004949)

		OriGene 3'-UTR Clone (see all 2): AMMECR1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AMMECR1
		8/101 QIAGEN miScript miRNA Assays for microRNAs that regulate AMMECR1 (see all 101):
		hsa-miR-3678-3p hsa-miR-300 hsa-miR-631 hsa-miR-15a hsa-miR-134 hsa-miR-508-5p hsa-miR-3613-3p hsa-miR-556-3p

		SwitchGear 3'UTR luciferase reporter plasmid: AMMECR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AMMECR1 (see all 4) OriGene shRNA RFP: AMMECR1 OriGene siRNA: AMMECR1
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for AMMECR1

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		Search LifeMap BioReagents cell lines for AMMECR1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMMECR1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

AMMECR1 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Ammecr1):

endocrine/exocrine gland

AMMECR1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for AMMECR1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

5/9 Interacting proteins for AMMECR1 (Q9Y4X0² ENSP00000262844⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LRP6	O75581²	MINT-8183661 MINT-8183545 MINT-8183643 MINT-8183454 MINT-8183525 MINT-8183678
AXIN2	Q9Y2T1²	MINT-8183587 MINT-8183606
GSK3B	P49841²	MINT-8183566 MINT-8183507
AXIN1	O15169²	MINT-8183476
CSNK1G1	Q9HCP0²	MINT-8183463

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

AMMECR1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AMMECR1
Search CenterWatch for drugs/clinical trials and news about AMMECR1 / AMMR1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for AMMECR1 gene (3 alternative transcripts):

NM_001025580.1 NM_001171689.1 NM_015365.2

Unigene Cluster for AMMECR1:

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

Hs.656243 [show with all ESTs]

Unigene Representative Sequence: NM_001171689

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000262844(uc004eoo.3 uc004eop.3 uc004eoq.3) ENST00000372059

ENST00000372057 ENST00000473662 ENST00000496695

miRNA Products:		OriGene 3'-UTR Clone (see all 2): AMMECR1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AMMECR1
		8/101 QIAGEN miScript miRNA Assays for microRNAs that regulate AMMECR1 (see all 101):
		hsa-miR-3678-3p hsa-miR-300 hsa-miR-631 hsa-miR-15a hsa-miR-134 hsa-miR-508-5p hsa-miR-3613-3p hsa-miR-556-3p

		SwitchGear 3'UTR luciferase reporter plasmid: AMMECR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AMMECR1

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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AMMECR1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AMMECR1

Additional cDNA sequence:

AJ007014.1 AJ009817.1 AK001703.1 AK023637.1 AK055321.1 AK091430.1 AK314596.1 AY007113.1

BC024762.1 BC037983.1 BC051895.1 BC060813.1 BC065214.1 BX648797.1

7 DOTS entries:

DT.414160 DT.100775746 DT.409779 DT.97779436 DT.95337543 DT.40197073 DT.40299115

24/141 AceView cDNA sequences (see all 141):

CF122286 AA587009 AW071564 AK055321 BU620429 BU754062 AI457994 BC065214

AI367410 BC024762 AA633657 BC060813 BU618668 BC051895 BM670607 AU118458

AA252395 NM_015365 AI458082 AW592504 AI813512 CB270434 AI032981 AI434792

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for AMMECR1 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b
SP1:							-
SP2:							-		-
SP3:

ECgene alternative splicing isoforms for AMMECR1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

AMMECR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGGCTTTA

About this image

AMMECR1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Nkx2-1 GFP+ cells (Efficient derivation...)

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See AMMECR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AMMECR1

SOURCE GeneReport for Unigene cluster: Hs.656243

SABiosciences Custom PCR Arrays for AMMECR1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AMMECR1 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMMECR1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for AMMECR1 gene from 9/33 species (see all 33) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ammecr1^{1 , 5}	Alport syndrome, mental retardation, midface hypoplasia more^{1, 5}	93.82(n)¹ 97.87(a)¹		X (63.74 cM)⁵ 56068¹ NM_019496.3¹ NP_062369.1¹ 142851146⁵
chicken (Gallus gallus)	Aves	AMMECR1¹	Alport syndrome, mental retardation, midface hypoplasia more	89.67(n) 92.58(a)		422343 XM_001234034.2 XP_001234035.2
lizard (Anolis carolinensis)	Reptilia	AMMECR1⁶	--	83(a)	1 ↔ 1	GL343376.1(18693-89333)
African clawed frog (Xenopus laevis)	Amphibia	Xl.25825²	Xenopus laevis transcribed sequence with moderate similarity more	81.71(n)		BQ730780.1
zebrafish (Danio rerio)	Actinopterygii	zgc66100²	similar to AMMECR1 protein	83.36(n)		393553 BC056704.1
fruit fly (Drosophila melanogaster)	Insecta	CG5902^{1 , 3}	CG5902¹	67(a)³ 63.19(n)¹ 67.19(a)¹		42839¹ NM_170106.3¹ NP_732929.1¹
worm (Caenorhabditis elegans)	Secernentea	R166.3^{1 , 3}	Protein R166.3¹	46(a)³ 53.65(n)¹ 47.92(a)¹		II(10537834-10539240)³ 174621¹ NM_063869.3¹ NP_496270.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G38710¹	AMMECR1 protein	55.56(n) 54.64(a)		818453 NM_001036432.1 NP_001031509.1
rice (Oryza sativa)	Liliopsida	Os10g0573100¹	hypothetical protein	58.51(n) 52.13(a)		4349471 NM_001072001.1 NP_001065469.1

ENSEMBL Gene Tree for AMMECR1 (if available)
TreeFam Gene Tree for AMMECR1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for AMMECR1 gene

AMMECR1L²

1 SIMAP similar gene for AMMECR1 using alignment to 1 protein entry: AMMR1_HUMAN:

AMMECR1L

AMMECR1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs111757306^1,2	C,	--	109436964(+)	`CAGATA/GATTTA`	3	--	ds500¹		1		CSA	1
rs190944245^1,2		--	109437068(+)	`GCTCCC/TGCCAG`	3	--	ds500¹		0	--	--	--	--
rs147340922^1,2		--	109437165(+)	`AATAAA/TGGCTA`	3	--	ds500¹		0	--	--	--	--
rs183313414^1,2		--	109437352(+)	`GTACCA/GACGAG`	3	--	ds500¹		0	--	--	--	--
rs139052898^1,2		--	109437354(+)	`ACCGAC/TGAGAC`	3	--	ds500¹		0	--	--	--	--
rs12843653^1,2	C,H	--	109437683(+)	`GTCTTA/CCGGTA`	3	--	ut3¹		5		NS EA NA	420
rs12843664^1,2	C	--	109437697(+)	`AAAAAA/CCAGGT`	3	--	ut3¹ ese³		0	--	--	--	--
rs188580033^1,2		--	109437865(+)	`ATATTC/TCAAAA`	3	--	ut3¹		0	--	--	--	--
rs112847985^1,2	C,	--	109438020(+)	`CATATC/ATTTGT`	3	--	ut3¹		1		CSA	1
rs192974968^1,2		--	109438713(+)	`GTACTA/GTTTCC`	3	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for AMMECR1 (109437414 - 109683461 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for AMMECR1
2 CNVs: 1863 4164
Locus Specific Mutation Databases (LSDB): AMMECR1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AMMECR1

DNA2.0 Custom Variant and Variant Library Synthesis for AMMECR1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

AMMECR1 for disorders About GeneDecksing

OMIM gene information: 300195 OMIM disorders: --

UniProtKB/Swiss-Prot: AMMR1_HUMAN, Q9Y4X0

Defects in AMMECR1 are involved in Alport syndrome with mental retardation midface hypoplasia and

elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by

glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis

5 diseases for AMMECR1: About MalaCards

alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis alport syndrome elliptocytosis intellectual disability

malaria

1 disease from the University of Copenhagen DISEASES database for AMMECR1:

Alport syndrome

Export disorders for AMMECR1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for AMMECR1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with AMMECR1)

Utopia: connect your pdf to the dynamic
world of online information

Identification and characterization of a highly conserved protein absent in the Alport syndrome (A), mental retardation (M), midface hypoplasia (M), and elliptocytosis (E) contiguous gene deletion syndrome (AMME). (PubMed id 10049589)^{1, 2, 3} Vitelli F.... Renieri A. (1999)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation. (PubMed id 9480748)^{1, 3} Piccini M....Renieri A. (1998)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Crystal structure of PH0010 from Pyrococcus horikoshii, which is highly homologous to human AMMECR 1C-terminal region. (PubMed id 15558565)¹ Tajika Y....Tanaka I. (2005)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9949	HGNC: 467	AceView: AMMECR1	Ensembl:ENSG00000101935	euGenes: HUgn9949
ECgene: AMMECR1	H-InvDB: AMMECR1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for AMMECR1	Pharmacogenomics, SNPs, Pathways

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Patent Information for AMMECR1 gene:
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