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AMHR2 Gene

protein-coding GIFtS: 63

GC12P052103

anti-Mullerian hormone receptor, type II
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AMHR ^², ³, ⁵
EC 2.7.11.30 ^³
MISR2 ^¹, ²
MISRII ^¹, ², ³
MRII ^³

Descriptions
AMH type II receptor ^³
Anti-Muellerian hormone type II receptor ^³
MIS type II receptor ^³
Mullerian inhibiting substance type II receptor ^²
anti-Mullerian hormone receptor, type II ^²

External Ids
HGNC: 465¹
Entrez Gene: 269²
UniProtKB: Q16671³
Ensembl: ENSG00000135409⁷

Search outside databases for aliases for AMHR2 gene

Previous GC identifers: GC12P053823 GC12P053925 GC12P053534

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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UniProtKB/Swiss-Prot: AMHR2_HUMAN, Q16671

Function: On ligand binding, forms a receptor complex consisting of two type II and two type I

transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I

receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.

Receptor for anti-Muellerian hormone

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the AMHR2 gene

Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.13 HGNC cytogenetic band: 12q13

AMHR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P052103: (about GC identifiers)

Start:	52,103,908 bp from pter
End:	52,111,579 bp from pter
Size:	7,672 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_029419.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: AMHR2_HUMAN, Q16671 (See protein sequence)

Recommended Name: Anti-Muellerian hormone type-2 receptor precursor

Size: 573 amino acids; 62750 Da

Cofactor: Magnesium or manganese (By similarity)

Subcellular location: Membrane; Single-pass type I membrane protein

Secondary accessions: A0AVE1 Q13762

REFSEQ proteins: NP_065434.1

ENSEMBL proteins:

ENSP00000369117 ENSP00000257863

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich CompoZr ZFN for AMHR2
	R&D Systems Recombinant & Natural Proteins for AMHR2 (MIS RII)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (AMHR2)
	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Protein: AMHR2

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	IEA	--
GO:0016020	membrane	IEA	--

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Antibodies for AMHR2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for AMHR2
	R&D Systems Antibodies for AMHR2 (MIS RII)
	Cell Signaling Technology (CST) Antibodies for AMHR2 (MIS-R2)
	Antibodies from Abcam (AMHR2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (AMHR2)
	Search Novus for antibodies for AMHR2

Assays for AMHR2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q16671

ProtoNet protein and cluster: Q16671

1 Blocks protein family: IPB000472 Domain in TGF-beta receptor/activin receptor

UniProtKB/Swiss-Prot: AMHR2_HUMAN, Q16671

Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB

receptor subfamily

Similarity: Contains 1 protein kinase domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AMHR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AMHR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020547

Applied Biosystems Silencer® siRNAs for AMHR2

Sigma-Aldrich siRNA and siRNA Panels for AMHR2

Sigma-Aldrich shRNA Panels and shRNA for AMHR2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_020547
Myc/DDK tagged cDNA clone in CMV expression vector: NM_020547
untagged cDNA clone in CMV expression vector: NM_020547

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_020547

UniProtKB/Swiss-Prot: AMHR2_HUMAN, Q16671

Function: On ligand binding, forms a receptor complex consisting of two type II and two type I

transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I

receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.

Receptor for anti-Muellerian hormone

Catalytic activity: ATP + [receptor-protein] = ADP + [receptor-protein] phosphate

Enzyme Number (IUBMB): EC 2.7.11.30

Genatlas biochemistry entry for AMHR2:

anti-Mullerian hormone receptor TGF,beta superfamily

6 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Amhr2):

	endocrine/exocrine gland	homeostasis/metabolism	no phenotypic analysis	reproductive system
tumorigenesis

5/11 Gene Ontology (GO) molecular function terms (links to tree view) (see all 11 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0000287	magnesium ion binding	IEA	--
GO:0004674	protein serine/threonine kinase activity	IEA	--
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEA	--
GO:0004872	receptor activity	IMP	7493017

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for AMHR2 (Your Favorite Gene powered by Ingenuity)

TGF-&beta

GeneDecks AMHR2 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for AMHR2

5/26 Interacting proteins for AMHR2 (ENSP00000257863³) via UniProtKB, MINT, and/or STRING (see all 26 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AMH	ENSP00000221496³	STRING (score=.996)
NR5A1	ENSP00000362690³	STRING (score=.951)
BMPR1B	ENSP00000264568³	STRING (score=.936)
CTNNB1	ENSP00000344456³	STRING (score=.915)
BMP2	ENSP00000368104³	STRING (score=.903)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001880	Mullerian duct regression	NAS	14750901
GO:0006468	protein amino acid phosphorylation	IEA	--
GO:0007165	signal transduction	IMP	7493017
GO:0007179	transforming growth factor beta receptor signaling pathway	IEA	--
GO:0007530	sex determination	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for AMHR2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (AMHR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (AMHR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020547

Sigma-Aldrich siRNA and siRNA Panels for AMHR2

Sigma-Aldrich shRNA Panels and shRNA for AMHR2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_020547

REFSEQ mRNAs for AMHR2 gene:

NM_020547.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_020547

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020547
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_020547
                                 untagged cDNA clone in CMV expression vector: NM_020547

Additional cDNA sequence:

AF172932.1 AK313593.1 AY714878.1 BC126316.1 BC136356.1 CR627318.1

4 DOTS entries:

DT.107029 DT.95226426 DT.87046621 DT.121155771

19 AceView cDNA sequences:

BX279985 NM_020547 AW293907 AW082199 AY714878 BE503494 CR627318 BE410788

AF172932 BF970811 BQ712311 BE409048 AJ572328 AI339400 BM008020 AA459833

BF434713 N87881 AA460023

highest scoring ESTs for AMHR2:

U29700 AF172932 AI339400 AW082199 BE503494 BX279985 AA459833 AJ572328 AW293907 AY714878

Unigene Cluster for AMHR2:

Anti-Mullerian hormone receptor, type II

Hs.659889 [show with all ESTs]

Unigene Representative Sequence: CR627318

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for AMHR2

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12
SP1:									-		-
SP2:													-				-
SP3:			-
SP4:													-

About this scheme

ECgene alternative splicing isoforms for AMHR2

2 Ensembl transcripts including schematic representations:

ENST00000379791 ENST00000257863

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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AMHR2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for AMHR2

¹ / ² / ³

3 probe-sets matching AMHR2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35502_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U29700	0.20	1.00	0.72	1
206892_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_020547	0.40	0.67	0.55	1
206892_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks AMHR2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCAACATAAA

SOURCE GeneReport for Unigene cluster: Hs.659889
Expression variation in blood from EXPOLDB for AMHR2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for AMHR2 gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	AMHR2¹	--	anti-Mullerian hormone receptor, type II	89.2(n) 86.41(a)	486506 XM_543632.2 XP_543632.2
chimpanzee (Pan troglodytes)	AMHR2¹	--	anti-Mullerian hormone receptor, type II	99.65(n) 99.65(a)	467005 XM_522405.2 XP_522405.2
rat (Rattus norvegicus)	Amhr2¹	--	anti-Mullerian hormone receptor, type II	82.35(n) 79.53(a)	29530 NM_030998.1 NP_112260.1
mouse (Mus musculus)	Amhr2^{1, 5}	15 (57.40 cM)⁵	anti-Mullerian hormone type 2 receptor^{1, 5}	83.18(n)¹ 80.43(a)¹	110542¹ NM_144547.1¹ NP_653130.1¹ AA647718⁵ AF503863⁵ (see all 7)

About this table Species with no ortholog for AMHR2

ENSEMBL Gene Tree for AMHR2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for AMHR2 gene

BMPR2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/64 NCBI SNPs in AMHR2 are shown (see all 64 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 32)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10876455^1,2	A,C,F,H	52111592(+)	`TTGTCT/CGCCTC`	1	--	ng3¹		8		NA EU EA	622
	rs2002555^1,2	C,F,H	52103504(-)	`GCAACT/CGCTTG`	1	--	ng5¹		15		EU EA WA NA	1340
--	rs2683523^1,2	A,C	52102089(-)	`gccacC/Tgcgcc`	1	--	ng5¹		0	--	--	--	--
--	rs7970368^1,2	C	52102241(+)	`tgtagG/Tcccag`	1	--	ng5¹		0	--	--	--	--
	rs12228117^1,2	H	52103462(+)	`ACAAGG/TTAACC`	1	--	ng5¹		4		EU EA WA	420
	rs784890^1,2	C,F,H,O	52109574(-)	`GCACAC/TGATCC`	1	S/S	syn¹ ese³		8		EU EA WA NA	624
	rs2071558^1,2	A,C,F,H,O	52105734(+)	`GTCCCC/TAGCAG`	1	--	int¹		12		EA NA EU WA	2414
	rs2272002^1,2	A,C,F,H,O	52104183(-)	`ACCTGA/TGCCCT`	1	--	int¹		8		EA NA EU WA	2040
	rs784893^1,2	A,C,F,H	52104554(-)	`CACCCT/CAGCCA`	1	--	int¹		4		EU EA WA	412
	rs784888^1,2	A,C,F,H	52110775(-)	`TAGAAC/GTGCCT`	1	--	int¹		8		EU EA WA	838

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HapMap Linkage Disequilibrium images for AMHR2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 600956 disorders: 261550

UniProtKB/Swiss-Prot: AMHR2_HUMAN, Q16671

Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2)

[MIM:261550]. PMDS-2 is a form of male pseudohermaphroditism characterized by a failure of

Muellerian duct regression in otherwise normal males

6 Novoseek disease relationships for AMHR2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
congenital absence	55.38	1	11223848 (1)
ovarian cancer	41.65	1	17088539 (1)
cervical cancer	18.16	2	14671316 (2)
prostate cancer	13.20	1	11773638 (1)
breast cancer	0.00	1	10874041 (1)
tumors	0.00	3	8889695 (1), 14656474 (1), 15728372 (1)

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Genatlas disease: AMHR2

persistent Mullerian duct syndrome

Human Gene Mutation Database: AMHR2
Genetic Association Database: AMHR2
Human Genome Epidemiology Navigator: AMHR2 (5 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/51 PubMed articles for AMHR2 gene (see all 51 ):

Insensitivity to anti-Muellerian hormone due to a mutation in the human anti-Muellerian hormone receptor. (PubMed id 7493017)^{2, 3, 4} Imbeaud S.... Picard J.-Y. (1995)
Human ovarian cancer, cell lines, and primary ascites cells express the human Muellerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS. (PubMed id 10589763)^{1, 3, 4} Masiakos P.T.... Donahoe P.K. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Mutational analysis of the mullerian-inhibiting substance gene and its receptor gene in Japanese women with polycystic ovary syndrome and premature ovarian failure. (PubMed id 12477536)^{3, 6} Wang H.Q....Noda Y. (2002)
Autosomal recessive segregation of a truncating mutation of anti- Muellerian type II receptor in a family affected by the persistent Muellerian duct syndrome contrasts with its dominant negative activity in vitro. (PubMed id 11549681)^{3, 4} Messika-Zeitoun L.... di Clemente N. (2001)
A 27 base-pair deletion of the anti-Muellerian type II receptor gene is the most common cause of the persistent Muellerian duct syndrome. (PubMed id 8872466)^{3, 4} Imbeaud S.... Picard J.-Y. (1996)
Structure and chromosomal localization of the human anti-Muellerian hormone type II receptor gene. (PubMed id 7488027)^{3, 4} Visser J.A.... Themmen A.P.N. (1995)
A polymorphism in the AMH type II receptor gene is associated with age at menopause in interaction with parity. (PubMed id 17636279)^{1, 3} Kevenaar M.E....Visser J.A. (2007)
Anti-Mullerian hormone and anti-Mullerian hormone type II receptor polymorphisms are associated with follicular phase estradiol levels in normo-ovulatory women. (PubMed id 17337470)^{1, 3} Kevenaar M.E....Visser J.A. (2007)
Anti-Mullerian hormone, its receptor, FSH receptor, and androgen receptor genes are overexpressed by granulosa cells from stimulated follicles in women with polycystic ovary syndrome. (PubMed id 18697861)^{1, 3} Catteau-Jonard S....di Clemente N. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 269	HGNC: 465	AceView: AMHR2	Ensembl:ENSG00000135409	euGenes: HUgn269
ECgene: AMHR2	H-InvDB: AMHR2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for AMHR2	Genetics and Cytogenetics in Oncology and Haematology
Wikipedia	http://en.wikipedia.org/wiki/Anti-m%C3%BCllerian_hormone

Licensable Technologies for AMHR2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for AMHR2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for AMHR2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for AMHR2		Antibodies for AMHR2
	Explore super-pooled esiRNAs		Proteins for AMHR2
	Lentivirus-delivered shRNAs for AMHR2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for AMHR2 (MIS-R2)

	Recombinant Proteins (AMHR2)
	Antibodies (AMHR2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for AMHR2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for AMHR2

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AMHR2 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for AMHR2

Summaries
for AMHR2

Genomic Location
for AMHR2

Proteins
for AMHR2

Protein Domains/
Families
for AMHR2

Gene Function
for AMHR2

Pathways & Interactions
for AMHR2

Drugs & Compounds
for AMHR2

Transcripts
for AMHR2

Expression
for AMHR2

Orthologs
for AMHR2

Paralogs
for AMHR2

SNPs/Variants
for AMHR2

Disorders & Mutations
for AMHR2

Medical News
for AMHR2

Publications
for AMHR2

Search for AMHR2

Genome Databases showing AMHR2

Other Databases showing AMHR2

Specialized Databases showing AMHR2

Licensable Technologies
for AMHR2

Services
for AMHR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

AMHR2 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor AMHR2

Summariesfor AMHR2

Genomic Locationfor AMHR2

Proteinsfor AMHR2

Protein Domains/Familiesfor AMHR2

Gene Functionfor AMHR2

Pathways & Interactionsfor AMHR2

Drugs & Compoundsfor AMHR2

Transcriptsfor AMHR2

Expression for AMHR2

Orthologsfor AMHR2

Paralogsfor AMHR2

SNPs/Variantsfor AMHR2

Disorders & Mutationsfor AMHR2

Medical Newsfor AMHR2

Publicationsfor AMHR2

Search for AMHR2

Genome Databases showing AMHR2

Other Databases showing AMHR2

Specialized Databases showing AMHR2

Licensable Technologiesfor AMHR2

Servicesfor AMHR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for AMHR2

Summaries
for AMHR2

Genomic Location
for AMHR2

Proteins
for AMHR2

Protein Domains/
Families
for AMHR2

Gene Function
for AMHR2

Pathways & Interactions
for AMHR2

Drugs & Compounds
for AMHR2

Transcripts
for AMHR2

Expression
for AMHR2

Orthologs
for AMHR2

Paralogs
for AMHR2

SNPs/Variants
for AMHR2

Disorders & Mutations
for AMHR2

Medical News
for AMHR2

Publications
for AMHR2

Licensable Technologies
for AMHR2

Services
for AMHR2