External Ids for AMELY Gene
Previous HGNC Symbols for AMELY Gene
Previous GeneCards Identifiers for AMELY Gene
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008]
GeneCards Summary for AMELY Gene
AMELY (Amelogenin, Y-Linked) is a Protein Coding gene. Diseases associated with AMELY include ameloblastoma. GO annotations related to this gene include structural constituent of tooth enamel. An important paralog of this gene is AMELX.
UniProtKB/Swiss-Prot for AMELY Gene
Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.