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AMDHD2 Gene

protein-coding   GIFtS: 50
GCID: GC16P002570

Amidohydrolase Domain Containing 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Amidohydrolase Domain Containing 21 2
Amidohydrolase Domain-Containing Protein 22 3
GlcNAc 6-P Deacetylase2 3
EC 3.5.1.253 8
Putative N-Acetylglucosamine-6-Phosphate Deacetylase2

External Ids:    HGNC: 242621   Entrez Gene: 510052   Ensembl: ENSG000001620667   UniProtKB: Q9Y3033   

Export aliases for AMDHD2 gene to outside databases

Previous GC identifer: GC16P002511


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for AMDHD2 Gene:
AMDHD2 (amidohydrolase domain containing 2) is a protein-coding gene. GO annotations related to this gene include N-acetylglucosamine-6-phosphate deacetylase activity. An important paralog of this gene is ENSG00000259784.

UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
Function: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the
N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of
Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the AMDHD2 gene promoter:
         CREB   Elk-1   p53   SREBP-1a   SREBP-1c   FOXO3   CUTL1   SREBP-1b   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAMDHD2 promoter sequence
   Search Chromatin IP Primers for AMDHD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AMDHD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

AMDHD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMDHD2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P002570:  view genomic region     (about GC identifiers)

Start:
2,570,358 bp from pter      End:
2,581,423 bp from pter
Size:
11,066 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303 (See protein sequence)
Recommended Name: Putative N-acetylglucosamine-6-phosphate deacetylase  
Size: 409 amino acids; 43748 Da
Cofactor: Binds 1 divalent metal cation per subunit (By similarity)
Sequence caution: Sequence=AAD27723.1; Type=Frameshift; Positions=5, 7, 11, 103, 113, 117, 192, 194, 195, 202,
205;
Secondary accessions: B4DL77 Q8WV54
Alternative splicing: 3 isoforms:  Q9Y303-1   Q9Y303-2   Q9Y303-3   

Explore the universe of human proteins at neXtProt for AMDHD2: NX_Q9Y303

Explore proteomics data for AMDHD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for AMDHD2 (Q9Y303) (see all 8)
     THLFNAM  PAALRIA  GRHTLGQQ  ATYISGELVWQ 


    See AMDHD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139287.1  NP_057028.2  

    ENSEMBL proteins: 
     ENSP00000457136   ENSP00000293971   ENSP00000307481   ENSP00000391596   ENSP00000457021  
     ENSP00000456898   ENSP00000457398   ENSP00000456656  

    AMDHD2 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for AMDHD2
    OriGene Custom MassSpec
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    Novus Biologicals AMDHD2 Protein
    Novus Biologicals AMDHD2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AMDHD2

     
    Search eBioscience for Proteins for AMDHD2 

     
    antibodies-online proteins for AMDHD2 (6 products) 

     
    antibodies-online peptides for AMDHD2

    AMDHD2 Antibody Products:

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    antibodies-online antibodies for AMDHD2 (14 products) 

    AMDHD2 Assay Products:

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    antibodies-online kits for AMDHD2 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR011059 Metal-dep_hydrolase_composite
     IPR003764 GlcNAc_6-P_deAcase

    Graphical View of Domain Structure for InterPro Entry Q9Y303

    ProtoNet protein and cluster: Q9Y303

    2 Blocks protein domains:
    IPB011550 Amidohydrolase-like
    IPB013108 Amidohydrolase 3


    UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
    Similarity: Belongs to the NagA family


    Find genes that share domains with AMDHD2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAGA_HUMAN, Q9Y303
    Function: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the
    N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of
    Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded
    Catalytic activity: N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate

         Enzyme Number (IUBMB): EC 3.5.1.251 2

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008448N-acetylglucosamine-6-phosphate deacetylase activity IDA--
    GO:0016787hydrolase activity ----
    GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ----
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with AMDHD2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for AMDHD2

    miRNA
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    miRTarBase miRNAs that target AMDHD2:
    hsa-mir-26b-5p (MIRT030119)

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    3 qRT-PCR Assays for microRNAs that regulate AMDHD2:
    hsa-miR-4254 hsa-miR-4308 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidAMDHD2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat AMDHD2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): AMDHD2 (NM_015944)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AMDHD2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMDHD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    cytosol1
    endoplasmic reticulum1
    extracellular1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for AMDHD2 About    
    See pathways by source

    SuperPathContained pathways About
    1Amino sugar and nucleotide sugar metabolism
    Amino sugar and nucleotide sugar metabolism
    N-acetylglucosamine degradation I0.00
    N-acetylglucosamine degradation II0.00


    Find genes that share SuperPaths with AMDHD2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for AMDHD2
        N-acetylglucosamine degradation I
    N-acetylglucosamine degradation II


    1 Kegg Pathway  (Kegg details for AMDHD2):
        Amino sugar and nucleotide sugar metabolism

    UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
    Pathway: Amino-sugar metabolism; N-acetylneuraminate degradation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for AMDHD2
    Interactions:

        Search GeneGlobe Interaction Network for AMDHD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for AMDHD2 (Q9Y3033 ENSP000003074814) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PKMP146183, ENSP000003201714I2D: score=1 STRING: ENSP00000320171
    GNPDA1P469263, ENSP000003118764I2D: score=5 STRING: ENSP00000311876
    GFPT1ENSP000003543474STRING: ENSP00000354347
    GFPT2ENSP000002537784STRING: ENSP00000253778
    HK2ENSP000002905734STRING: ENSP00000290573
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--
    GO:0006044N-acetylglucosamine metabolic process IEA--
    GO:0019262N-acetylneuraminate catabolic process TAS--

    Find genes that share ontologies with AMDHD2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for AMDHD2 (NAGA)

    4 HMDB Compounds for AMDHD2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetic acidAcetate (see all 12)64-19-7--
    Glucosamine 6-phosphate2-Amino-2-deoxy-D-glucose 6-phosphate (see all 14)3616-42-0--
    N-Acetyl-D-Glucosamine 6-PhosphateN-Acetyl-D-Glucosamine 6-Phosphate (see all 7)102029-88-9--
    WaterDihydrogen oxide (see all 2)7732-18-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for AMDHD2 gene (2 alternative transcripts): 
    NM_001145815.1  NM_015944.3  

    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568263 ENST00000293971 ENST00000302956(uc002cqp.3 uc002cqq.3 uc010uwc.2 uc010uwd.2)
    ENST00000565963 ENST00000413459 ENST00000563633 ENST00000567475 ENST00000569219
    ENST00000566706 ENST00000569879 ENST00000563556 ENST00000565570 ENST00000570028
    ENST00000566947 ENST00000561487 ENST00000563444 ENST00000563145 ENST00000563453

    miRNA
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    Block miRNA regulation of human, mouse, rat AMDHD2 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate AMDHD2:
    hsa-miR-4254 hsa-miR-4308 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidAMDHD2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for AMDHD2
    Predesigned siRNA for gene silencing in human, mouse, rat AMDHD2
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    Primer
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    OriGene qPCR primer pairs and template standards for AMDHD2
    OriGene qSTAR qPCR primer pairs in human, mouse for AMDHD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat AMDHD2
      QuantiTect SYBR Green Assays in human, mouse, rat AMDHD2
      QuantiFast Probe-based Assays in human, mouse, rat AMDHD2

    Selected AceView cDNA sequences (see all 585):

    BQ681490 BU859032 BQ878221 BU194635 BM820227 BQ058594 AI342392 BG741416 
    CR616464 CR599331 CB529900 BF436248 AW025951 AW300535 BU620642 AI651276 
    BM554691 AW246536 AI865257 CF126196 BE467119 CR624902 BQ678034 Z40632 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for AMDHD2 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c
    SP1:                                                  -                                                                 -                                 
    SP2:                                                                                                                    -                                 
    SP3:                                                  -     -                                                           -                                 
    SP4:                                                  -     -                                                                                             
    SP5:                                -     -           -                                                                                                   


    ECgene alternative splicing isoforms for AMDHD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    AMDHD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTCGGCCC
    AMDHD2 Expression
    About this image


    AMDHD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Intervertebral Disc Nucleus Pulposus Cells Nucleus Pulposus
             Nucleus Pulposus
     
     Primitive Streak (Early Embryonic Tissues)
             Notochord
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
    AMDHD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    AMDHD2 Protein Expression
        Custom PCR Arrays for AMDHD2
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    QuantiFast Probe-based Assays in human, mouse, rat AMDHD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMDHD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for AMDHD2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Amdhd21 , 5 amidohydrolase domain containing 21, 5 86.24(n)1
    91.15(a)1
      17 (12.28 cM)5
    2458471  NM_172935.41  NP_766523.21 
     241558335 
    chicken
    (Gallus gallus)
    Aves AMDHD21 amidohydrolase domain containing 2 71.07(n)
    72.88(a)
      770465  XM_001232245.3  XP_001232246.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    N-acetylglucosamine-6-phosphate deacetylase
    69(a)
    1 → many
    GL343621.1(342975-354944)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia amdhd21 amidohydrolase domain containing 2 66.91(n)
    70.94(a)
      100145339  NM_001126811.1  NP_001120283.1 
    zebrafish
    (Danio rerio)
    Actinopterygii amdhd21 amidohydrolase domain containing 2 66.25(n)
    68.49(a)
      402981  NM_205681.1  NP_991244.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG170651 CG17065 63.78(n)
    59.8(a)
      33026  NM_001169334.1  NP_001162805.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F59B2.31 CELE_F59B2.3 51.69(n)
    52.03(a)
      176272  NM_066589.5  NP_498990.1 


    ENSEMBL Gene Tree for AMDHD2 (if available)
    TreeFam Gene Tree for AMDHD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for AMDHD2 gene
    ENSG000002597842  

    Find genes that share paralogs with AMDHD2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for AMDHD2 (see all 284)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0383014
    A colorectal cancer sample4--see VAR_0383012 D N mis40--------
    rs2020035051,2
    C--2570944(+) GAGGAA/GCTCTG 2 -- int10--------
    rs2011105691,2
    --2571046(+) CTCGTA/GGCCCG 4 V syn10--------
    rs1170200611,2
    C--2571073(+) GGCGTC/TACCTC 4 V syn11Minor allele frequency- T:0.01NA 120
    rs2006645121,2
    C--2571092(+) CCACCC/TTGGTC 4 L syn11Minor allele frequency- T:0.00EU 1193
    rs1471294731,2
    F--2571108(+) CCCACC/GGGAGG 4 P R mis11Minor allele frequency- G:0.00NA 4546
    rs1387267171,2
    C,F--2571122(+) ATCACA/GAGGTG 4 K E mis12Minor allele frequency- G:0.00NA EU 5643
    rs782727771,2
    C,F--2571234(+) GTCCTG/CAGTCT 2 -- int11Minor allele frequency- C:0.04NA 120
    rs80611021,2
    C,F,A,H--2571331(+) TCTGTC/TCTCCG 2 -- int18Minor allele frequency- T:0.02NS EA WA CSA 541
    rs1392647541,2
    --2571533(+) TGGAAC/TACGCC 2 -- int10--------

    HapMap Linkage Disequilibrium report for AMDHD2 (2570358 - 2581423 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for AMDHD2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    nsv833122CNV Loss17160897
    nsv905153CNV Loss21882294
    dgv2571n71CNV Loss21882294
    dgv2545n71CNV Loss21882294
    nsv905152CNV Loss21882294
    dgv2569n71CNV Loss21882294
    nsv905149CNV Loss21882294
    nsv905139CNV Loss21882294
    dgv2570n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    1 disease from the University of Copenhagen DISEASES database for AMDHD2:
    Infective endocarditis

    Find genes that share disorders with AMDHD2           About GenesLikeMe


    Export disorders for AMDHD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for AMDHD2 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with AMDHD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N- glycolylneuraminic acid. (PubMed id 22692205)2 Bergfeld A.K.... Varki A. (J. Biol. Chem. 2012)
    3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51005 HGNC: 24262 AceView: ATP6V0CandCGI-14andKIAA1171 Ensembl:ENSG00000162066 euGenes: HUgn51005
    ECgene: AMDHD2 Kegg: 51005 H-InvDB: AMDHD2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for AMDHD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for AMDHD2 gene:
    Search GeneIP for patents involving AMDHD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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