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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AMDHD2 Gene

protein-coding   GIFtS: 53
GCID: GC16P002570

Amidohydrolase Domain Containing 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Amidohydrolase Domain Containing 21 2
Amidohydrolase Domain-Containing Protein 22 3
GlcNAc 6-P Deacetylase2 3
EC 3.5.1.253 8
Putative N-Acetylglucosamine-6-Phosphate Deacetylase2

External Ids:    HGNC: 242621   Entrez Gene: 510052   Ensembl: ENSG000001620667   UniProtKB: Q9Y3033   

Export aliases for AMDHD2 gene to outside databases

Previous GC identifer: GC16P002511


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AMDHD2 Gene: 
AMDHD2 (amidohydrolase domain containing 2) is a protein-coding gene. Diseases associated with AMDHD2 include endocarditis, and infective endocarditis, and among its related super-pathways are N-acetylglucosamine degradation II. GO annotations related to this gene include N-acetylglucosamine-6-phosphate deacetylase activity and metal ion binding. An important paralog of this gene is ENSG00000259784.

UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
Function: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the
N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of
Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AMDHD2 gene promoter:
         CREB   Elk-1   p53   SREBP-1a   SREBP-1c   FOXO3   CUTL1   SREBP-1b   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAMDHD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for AMDHD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMDHD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

AMDHD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMDHD2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P002570:  view genomic region     (about GC identifiers)

Start:
2,570,358 bp from pter      End:
2,581,423 bp from pter
Size:
11,066 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303 (See protein sequence)
Recommended Name: Putative N-acetylglucosamine-6-phosphate deacetylase  
Size: 409 amino acids; 43748 Da
Cofactor: Binds 1 divalent metal cation per subunit (By similarity)
Sequence caution: Sequence=AAD27723.1; Type=Frameshift; Positions=5, 7, 11, 103, 113, 117, 192, 194, 195, 202,
205;
Secondary accessions: B4DL77 Q8WV54
Alternative splicing: 3 isoforms:  Q9Y303-1   Q9Y303-2   Q9Y303-3   

Explore the universe of human proteins at neXtProt for AMDHD2: NX_Q9Y303

Explore proteomics data for AMDHD2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y303

  • 4/8 DME Specific Peptides for AMDHD2 (Q9Y303) (see all 8)
     THLFNAM  PAALRIA  GRHTLGQQ  ATYISGELVWQ 

    AMDHD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AMDHD2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001139287.1  NP_057028.2  

    ENSEMBL proteins: 
     ENSP00000457136   ENSP00000293971   ENSP00000307481   ENSP00000391596   ENSP00000457021  
     ENSP00000456898   ENSP00000457398   ENSP00000456656  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR006680 Amidohydro_1
     IPR003764 GlcNAc_6-P_deAcase
     IPR011059 Metal-dep_hydrolase_composite

    Graphical View of Domain Structure for InterPro Entry Q9Y303

    ProtoNet protein and cluster: Q9Y303

    2 Blocks protein domains:
    IPB011550 Amidohydrolase-like
    IPB013108 Amidohydrolase 3


    UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
    Similarity: Belongs to the NagA family


    AMDHD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAGA_HUMAN, Q9Y303
    Function: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the
    N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of
    Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded
    Catalytic activity: N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate

         Enzyme Number (IUBMB): EC 3.5.1.251 2

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008448N-acetylglucosamine-6-phosphate deacetylase activity IDA--
    GO:0016787hydrolase activity ----
    GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ----
    GO:0046872metal ion binding IEA--
         
    AMDHD2 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidAMDHD2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AMDHD2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1N-acetylglucosamine degradation I
    N-acetylglucosamine degradation I0.75
    N-acetylglucosamine degradation II0.75
    2Amino sugar and nucleotide sugar metabolism
    Amino sugar and nucleotide sugar metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for AMDHD2
        N-acetylglucosamine degradation I
    N-acetylglucosamine degradation II


    1         Kegg Pathway  (Kegg details for AMDHD2):
        Amino sugar and nucleotide sugar metabolism

    UniProtKB/Swiss-Prot: NAGA_HUMAN, Q9Y303
    Pathway: Amino-sugar metabolism; N-acetylneuraminate degradation


    AMDHD2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AMDHD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/14 Interacting proteins for AMDHD2 (Q9Y3033 ENSP000003074814) via UniProtKB, MINT, STRING, and/or I2D (see all 14)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PKMP146183, ENSP000003201714I2D: score=1 STRING: ENSP00000320171
    GNPDA1P469263, ENSP000003118764I2D: score=5 STRING: ENSP00000311876
    GFPT1ENSP000003543474STRING: ENSP00000354347
    GFPT2ENSP000002537784STRING: ENSP00000253778
    NAGKENSP000002442044STRING: ENSP00000244204
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--
    GO:0006044N-acetylglucosamine metabolic process IEA--
    GO:0019262N-acetylneuraminate catabolic process TAS--

    AMDHD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AMDHD2 (NAGA)

    4 HMDB Compounds for AMDHD2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetic acidAcetate (see all 12)64-19-7--
    Glucosamine 6-phosphate2-Amino-2-deoxy-D-glucose 6-phosphate (see all 14)3616-42-0--
    N-Acetyl-D-Glucosamine 6-PhosphateN-Acetyl-D-Glucosamine 6-Phosphate (see all 7)102029-88-9--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    Search CenterWatch for drugs/clinical trials and news about AMDHD2 / NAGA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AMDHD2 gene (2 alternative transcripts): 
    NM_001145815.1  NM_015944.3  

    Unigene Cluster for AMDHD2:

    Amidohydrolase domain containing 2
    Hs.740430  [show with all ESTs]
    Unigene Representative Sequence: AB209351
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568263 ENST00000293971 ENST00000302956(uc002cqp.3 uc002cqq.3 uc010uwc.2 uc010uwd.2)
    ENST00000565963 ENST00000413459 ENST00000563633 ENST00000567475 ENST00000569219
    ENST00000566706 ENST00000569879 ENST00000563556 ENST00000565570 ENST00000570028
    ENST00000566947 ENST00000561487 ENST00000563444 ENST00000563145 ENST00000563453

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate AMDHD2:
    hsa-miR-4254 hsa-miR-4308 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidAMDHD2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB209351.1 AF132948.1 AK296877.1 AK300747.1 BC018734.1 

    19 DOTS entries:

    DT.65285095  DT.455139  DT.120680217  DT.100028439  DT.40107633  DT.120680309  DT.86854696  DT.100780591 
    DT.100780592  DT.414015  DT.100672691  DT.95089959  DT.100046940  DT.120680221  DT.91836506  DT.100741656 
    DT.91804655  DT.95192639  DT.95335453 

    24/585 AceView cDNA sequences (see all 585):

    BE467119 BQ279185 CD368869 BE645657 BQ422810 CA488146 BM784555 AI244842 
    CR592409 BM766673 BU846257 BM841916 BM826778 AI865257 CF127865 AW300535 
    AI620452 BF724419 AI393278 BI917005 AI375672 BQ681490 AA369054 BF057835 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for AMDHD2 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c
    SP1:                                                  -                                                                 -                                 
    SP2:                                                                                                                    -                                 
    SP3:                                                  -     -                                                           -                                 
    SP4:                                                  -     -                                                                                             
    SP5:                                -     -           -                                                                                                   


    ECgene alternative splicing isoforms for AMDHD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AMDHD2 expression in normal human tissues (normalized intensities)      AMDHD2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTCGGCCC
    AMDHD2 Expression
    About this image


    AMDHD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/16 selected tissues (see all 16) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             kidney ; cells in tubules   
     
     Smooth Muscle (Muscoskeletal System)
             smooth muscle ; smooth muscle cells   
     
     Colon (Gastrointestinal Tract)
             colon ; endothelial cells   
     
     Primitive Streak (Early Embryonic Tissues)
             Notochord
     
     Mesoderm (Gastrulation Derivatives)
             skeleton/axial skeleton   

    See AMDHD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AMDHD2

    SOURCE GeneReport for Unigene cluster: Hs.740430
        SABiosciences Custom PCR Arrays for AMDHD2
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AMDHD2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Amdhd21 , 5 amidohydrolase domain containing 21, 5 86.24(n)1
    91.15(a)1
      17 (12.28 cM)5
    2458471  NM_172935.41  NP_766523.21 
     241558335 
    chicken
    (Gallus gallus)
    Aves AMDHD21 amidohydrolase domain containing 2 71.15(n)
    72.88(a)
      770465  XM_001232245.2  XP_001232246.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    N-acetylglucosamine-6-phosphate deacetylase
    69(a)
    1 → many
    GL343621.1(342975-354944)
    zebrafish
    (Danio rerio)
    Actinopterygii amdhd21 amidohydrolase domain containing 2 66.25(n)
    68.49(a)
      402981  NM_205681.1  NP_991244.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG170651 CG17065 63.78(n)
    59.8(a)
      33026  NM_001169334.1  NP_001162805.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F59B2.31 Protein F59B2.3 51.82(n)
    52.16(a)
      176272  NM_066589.4  NP_498990.1 


    ENSEMBL Gene Tree for AMDHD2 (if available)
    TreeFam Gene Tree for AMDHD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AMDHD2 gene
    ENSG000002597842  

    AMDHD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/284 SNPs in AMDHD2 are shown (see all 284)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0383014
    A colorectal cancer sample4--see VAR_0383012 D N mis40--------
    rs2020035051,2
    C--2570944(+) GAGGAA/GCTCTG 2 -- int10--------
    rs2011105691,2
    --2571046(+) CTCGTA/GGCCCG 4 V syn10--------
    rs1170200611,2
    C--2571073(+) GGCGTC/TACCTC 4 V syn11Minor allele frequency- T:0.01NA 120
    rs2006645121,2
    C--2571092(+) CCACCC/TTGGTC 4 L syn11Minor allele frequency- T:0.00EU 1193
    rs1471294731,2
    F--2571108(+) CCCACC/GGGAGG 4 P R mis11Minor allele frequency- G:0.00NA 4546
    rs1387267171,2
    C,F--2571122(+) ATCACA/GAGGTG 4 K E mis12Minor allele frequency- G:0.00NA EU 5643
    rs782727771,2
    C,F--2571234(+) GTCCTG/CAGTCT 2 -- int11Minor allele frequency- C:0.04NA 120
    rs80611021,2
    C,F,A,H--2571331(+) TCTGTC/TCTCCG 2 -- int18Minor allele frequency- T:0.02NS EA WA CSA 541
    rs1392647541,2
    --2571533(+) TGGAAC/TACGCC 2 -- int10--------

    HapMap Linkage Disequilibrium report for AMDHD2 (2570358 - 2581423 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for AMDHD2 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    nsv833122CNV Loss17160897
    nsv905153CNV Loss21882294
    dgv2571n71CNV Loss21882294
    dgv2545n71CNV Loss21882294
    nsv905152CNV Loss21882294
    dgv2569n71CNV Loss21882294
    nsv905149CNV Loss21882294
    nsv905139CNV Loss21882294
    dgv2570n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for AMDHD2:    About MalaCards
    endocarditis    infective endocarditis    pneumonia    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for AMDHD2:
    Infective endocarditis

    AMDHD2 for disorders           About GeneDecksing


    Export disorders for AMDHD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AMDHD2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with AMDHD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N- glycolylneuraminic acid. (PubMed id 22692205)2 Bergfeld A.K.... Varki A. (2012)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51005 HGNC: 24262 AceView: ATP6V0CandCGI-14andKIAA1171 Ensembl:ENSG00000162066 euGenes: HUgn51005
    ECgene: AMDHD2 Kegg: 51005 H-InvDB: AMDHD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AMDHD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AMDHD2 gene:
    Search GeneIP for patents involving AMDHD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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