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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AMBRA1 Gene

protein-coding   GIFtS: 49
GCID: GC11M046417

Autophagy/Beclin-1 Regulator 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Autophagy/Beclin-1 Regulator 11 2     DCAF32
DDB1 And CUL4 Associated Factor 31 2     WDR942
WD Repeat Domain 941 2     Activating Molecule In Beclin-1-Regulated Autophagy2
KIAA17363 5     Activating Molecule In BECN1-Regulated Autophagy Protein 12

External Ids:    HGNC: 259901   Entrez Gene: 556262   Ensembl: ENSG000001104977   OMIM: 6113595   UniProtKB: Q9C0C73   

Export aliases for AMBRA1 gene to outside databases

Previous GC identifers: GC11M046375 GC11M046124


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AMBRA1 Gene: 
AMBRA1 (autophagy/beclin-1 regulator 1) is a protein-coding gene. Diseases associated with AMBRA1 include choroiditis, and neuronitis. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: AMRA1_HUMAN, Q9C0C7
Function: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein
turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AMBRA1 gene promoter:
         Pax-5   POU6F1 (c2)   C/EBPalpha   PPAR-gamma1   SRY   S8   HFH-1   PPAR-gamma2   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAMBRA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AMBRA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMBRA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p11.2   Ensembl cytogenetic band:  11p11.2   HGNC cytogenetic band: 11p11.2

AMBRA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMBRA1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M046417:  view genomic region     (about GC identifiers)

Start:
46,417,964 bp from pter      End:
46,615,675 bp from pter
Size:
197,712 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AMRA1_HUMAN, Q9C0C7 (See protein sequence)
Recommended Name: Activating molecule in BECN1-regulated autophagy protein 1  
Size: 1298 amino acids; 142507 Da
Subunit: Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3 (By similarity)
Subcellular location: Cytoplasmic vesicle, autophagosome (By similarity)
Sequence caution: Sequence=BAA91067.1; Type=Frameshift; Positions=682; Sequence=BAB14457.1; Type=Erroneous
initiation; Sequence=BAB21827.1; Type=Erroneous initiation;
Secondary accessions: A6XN33 D3DQP8 G3V193 Q86XD6 Q9H8Z0 Q9NXE7
Alternative splicing: 6 isoforms:  Q9C0C7-1   Q9C0C7-2   Q9C0C7-3   Q9C0C7-4   Q9C0C7-5   Q9C0C7-6   (No experimental confirmation available. Ref.4 (AL834190) sequence differs from that shown due to a frameshift in position 745)

Explore the universe of human proteins at neXtProt for AMBRA1: NX_Q9C0C7

Explore proteomics data for AMBRA1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9C0C7

  • AMBRA1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AMBRA1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001254711.1  NP_001254712.1  NP_060219.2  

    ENSEMBL proteins: 
     ENSP00000318313   ENSP00000433372   ENSP00000431926   ENSP00000415327   ENSP00000434895  
     ENSP00000433945   ENSP00000431486   ENSP00000410899   ENSP00000298834  

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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AMBRA1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA17589504
    GO:0005776autophagic vacuole IEA--
    GO:0031410cytoplasmic vesicle IEA--

    AMBRA1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DCAF: DDB1 and CUL4 associated factors
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9C0C7

    ProtoNet protein and cluster: Q9C0C7

    UniProtKB/Swiss-Prot: AMRA1_HUMAN, Q9C0C7
    Similarity: Contains 3 WD repeats


    AMBRA1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AMRA1_HUMAN, Q9C0C7
    Function: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein
    turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    AMBRA1 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ambra1):
     cellular  embryogenesis  mortality/aging  nervous system 

    AMBRA1 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidAMBRA1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AMBRA1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Senescence and Autophagy
    Senescence and Autophagy
    2Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for AMBRA1
        Neuroscience

    1 BioSystems Pathway for AMBRA1
        Senescence and Autophagy



    AMBRA1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AMBRA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/223 Interacting proteins for AMBRA1 (Q9C0C71, 2, 3 ENSP000003183134) via UniProtKB, MINT, STRING, and/or I2D (see all 223)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCL2P104152, 3, ENSP000003296234MINT-8182706 MINT-8182670 MINT-8182688 MINT-8182559 MINT-8182625 MINT-8174974 MINT-8182589 MINT-8182650 MINT-8182607 MINT-8182574 I2D: score=1 STRING: ENSP00000329623
    ENSG00000212866P081073I2D: score=1 
    ENSG00000215328P081073I2D: score=1 
    ENSG00000224501P081073I2D: score=1 
    ENSG00000231555P081073I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006914autophagy IEA--
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0009790embryo development ----
    GO:0021915neural tube development IEA--
    GO:0030154cell differentiation IEA--

    AMBRA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AMBRA1 (AMRA1)

    Search CenterWatch for drugs/clinical trials and news about AMBRA1 / AMRA1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AMBRA1 gene (3 alternative transcripts): 
    NM_001267782.1  NM_001267783.1  NM_017749.3  

    Unigene Cluster for AMBRA1:

    Autophagy/beclin-1 regulator 1
    Hs.654644  [show with all ESTs]
    Unigene Representative Sequence: AK302808
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314845(uc010rgt.1 uc001ncu.1) ENST00000533727(uc001ncv.2 uc001ncw.2)
    ENST00000534300(uc001ncx.2) ENST00000458649(uc010rgu.1) ENST00000526545
    ENST00000528950 ENST00000529553 ENST00000529963 ENST00000529558 ENST00000531542
    ENST00000524783 ENST00000526606 ENST00000426438(uc009ylc.1) ENST00000298834

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    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate AMBRA1 (see all 37):
    hsa-miR-642a hsa-miR-4254 hsa-miR-3194-5p hsa-miR-631 hsa-miR-429 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-9
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    Inhib. RNA
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    Additional mRNA sequence: 

    AB051523.1 AK000301.1 AK023197.1 AK057896.1 AK302808.1 AK304530.1 AL137611.1 AL834190.1 
    BC045609.1 DQ870924.1 

    13 DOTS entries:

    DT.100779368  DT.95338415  DT.107951  DT.95165030  DT.100779367  DT.102841099  DT.75108941  DT.120731309 
    DT.120731310  DT.91890877  DT.100829056  DT.120731304  DT.40221669 

    24/110 AceView cDNA sequences (see all 110):

    NM_017749 BF589843 BU956025 AI699895 CA306509 BU171968 BC045609 BU527699 
    AK057896 AB051523 CB149054 BP353292 AU159538 BM472696 AI791940 CB216101 
    BP352652 BM904226 BX281628 AU131702 AK023197 AW732859 BM699885 BU159882 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for AMBRA1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^
    SP1:                                                                                            -                 -                                             
    SP2:                    -                                                           -           -                 -                                             
    SP3:                    -                                                                 -     -                 -                                             
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                  -         

    ExUns: 22a · 22b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for AMBRA1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AMBRA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCTCAAAA
    AMBRA1 Expression
    About this image


    See AMBRA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AMBRA1

    SOURCE GeneReport for Unigene cluster: Hs.654644
        SABiosciences Expression via Pathway-Focused PCR Array including AMBRA1: 
              Autophagy in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMBRA1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for AMBRA1 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ambra11 , 5 autophagy/beclin 1 regulator 11, 5 84.88(n)1
    87.33(a)1
      2 (50.63 cM)5
    2283611  NM_172669.31  NP_766257.31 
     917301345 
    chicken
    (Gallus gallus)
    Aves AMBRA11 autophagy/beclin-1 regulator 1 79.62(n)
    86.15(a)
      423194  XM_001233288.2  XP_001233289.2 
    lizard
    (Anolis carolinensis)
    Reptilia AMBRA16
    Uncharacterized protein
    76(a)
    1 ↔ 1
    1(42796646-42974971)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.145122 Xenopus laevis transcribed sequences 81.52(n)    BX853367.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ambra11 autophagy/beclin-1 regulator 1 64.8(n)
    67.74(a)
      100332642  XM_002667669.2  XP_002667715.2 


    ENSEMBL Gene Tree for AMBRA1 (if available)
    TreeFam Gene Tree for AMBRA1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3140 SNPs in AMBRA1 are shown (see all 3140)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1810279951,2
    C--46324255(+) GGTCTC/TGATCT 2 -- us2k10--------
    rs780109291,2
    C--46324260(+) CGATCC/TTCTGA 2 -- us2k10--------
    rs105464761,2
    C--46365593(+) ttatt-/TAtatat 3 -- int10--------
    rs1112986011,2
    F--46417463(+) CTTTCG/AGCCAC 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs801388291,2
    C,F--46417616(+) CTGGCC/TAGTTA 3 -- int11Minor allele frequency- T:0.02NA 120
    rs729100961,2
    C,F--46417651(+) GGTGGG/AAAGCT 3 -- int11Minor allele frequency- A:0.02NA 120
    rs1472449951,2
    C--46417679(+) TCTGTC/TGTTCC 3 -- int10--------
    rs1487550281,2
    --46417813(+) CTCTGA/GCGAAG 3 -- int10--------
    rs14666351,2
    C,F,H--46417815(-) CCCTTC/TGCCAG 3 -- int116Minor allele frequency- T:0.09EA NA NS 1568
    rs1423056071,2
    --46417841(+) TGCACA/CCCACT 3 -- int10--------

    HapMap Linkage Disequilibrium report for AMBRA1 (46417964 - 46615675 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for AMBRA1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2658413CNV Deletion23128226
    nsv309CNV Loss18451855
    nsv825867CNV Gain20364138
    nsv897321CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611359    OMIM disorders: --

    2 diseases for AMBRA1:    About MalaCards
    choroiditis    neuronitis


    AMBRA1 for disorders           About GeneDecksing


    Export disorders for AMBRA1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AMBRA1 gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with AMBRA1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ambra1 regulates autophagy and development of the nervous system. (PubMed id 17589504)1, 2, 3 Fimia G.M....Cecconi F. (2007)
    2. A novel role for autophagy in neurodevelopment. (PubMed id 17622796)1, 3 Cecconi F....Piacentini M. (2007)
    3. Autophagy: a new regulator of development. (PubMed id 17603510)1, 3 Le Bot N. (2007)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
    6. Ambra1 at the crossroad between autophagy and cell dea th. (PubMed id 23069654)1 Fimia G.M....Piacentini M. (2013)
    7. mTOR inhibits autophagy by controlling ULK1 ubiquityla tion, self-association and function through AMBRA1 and TRAF6. (PubMed id 23524951)1 Nazio F....Cecconi F. (2013)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    10. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55626 HGNC: 25990 AceView: FLJ20294 Ensembl:ENSG00000110497 euGenes: HUgn55626
    ECgene: AMBRA1 H-InvDB: AMBRA1

    (According to HUGE)
    About This Section
    HUGE: KIAA1736

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AMBRA1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AMBRA1 gene:
    Search GeneIP for patents involving AMBRA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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