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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AMBN Gene

protein-coding   GIFtS: 50
GCID: GC04P071457

Ameloblastin (Enamel Matrix Protein)

(Previous names: ameloblastin, enamel matrix protein)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ameloblastin (Enamel Matrix Protein)1 2
Ameloblastin, Enamel Matrix Protein1
ameloblastin2

External Ids:    HGNC: 4521   Entrez Gene: 2582   Ensembl: ENSG000001785227   OMIM: 6012595   UniProtKB: Q9NP703   

Export aliases for AMBN gene to outside databases

Previous GC identifers: GC04U990004 GC04P071506 GC04M9L0081 GC04P071774 GC04P071638 GC04P067260


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AMBN Gene:
This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in
enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene
cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal
dominant amylogenesis imperfect. (provided by RefSeq, Aug 2011)

GeneCards Summary for AMBN Gene: 
AMBN (ameloblastin (enamel matrix protein)) is a protein-coding gene. Diseases associated with AMBN include dental pulp necrosis, and dentin dysplasia. GO annotations related to this gene include growth factor activity and structural constituent of tooth enamel.

UniProtKB/Swiss-Prot: AMBN_HUMAN, Q9NP70
Function: Involved in the mineralization and structural organization of enamel




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_022778.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AMBN gene promoter:
         HFH-3   AP-1   AML1a   POU3F2   GATA-2   GATA-1   Evi-1   Gfi-1   FOXI1   Chx10   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAMBN promoter sequence
   Search SABiosciences Chromatin IP Primers for AMBN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AMBN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21

AMBN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AMBN gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P071457:  view genomic region     (about GC identifiers)

Start:
71,457,973 bp from pter      End:
71,473,005 bp from pter
Size:
15,033 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AMBN_HUMAN, Q9NP70 (See protein sequence)
Recommended Name: Ameloblastin precursor  
Size: 447 amino acids; 48283 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: Q3B862 Q9H2X1 Q9H4L1
Alternative splicing: 2 isoforms:  Q9NP70-1   Q9NP70-2   

Explore the universe of human proteins at neXtProt for AMBN: NX_Q9NP70

Explore proteomics data for AMBN at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NP70

  • AMBN Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AMBN Protein Expression
    REFSEQ proteins: NP_057603.1  
    ENSEMBL proteins: 
     ENSP00000313809   ENSP00000391234  

    Human Recombinant Protein Products for AMBN: 
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    Novus Biologicals AMBN Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for AMBN 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix NAS--

    AMBN for ontologies           About GeneDecksing



    AMBN Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007798 Amelin

    Graphical View of Domain Structure for InterPro Entry Q9NP70

    ProtoNet protein and cluster: Q9NP70

    1 Blocks protein domain: IPB007798 Ameloblastin precursor

    UniProtKB/Swiss-Prot: AMBN_HUMAN, Q9NP70
    Similarity: Belongs to the ameloblastin family


    AMBN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AMBN_HUMAN, Q9NP70
    Function: Involved in the mineralization and structural organization of enamel

         Genatlas biochemistry entry for AMBN:
    ameloblastin,enamel sheath protein

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity ISS--
    GO:0030345structural constituent of tooth enamel NAS--
         
    AMBN for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ambn):
     craniofacial  skeleton  tumorigenesis 

    AMBN for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ambntm1Nid for AMBN

       inGenious Targeting Laboratory - Custom generated mouse model solutions for AMBN 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AMBN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AMBN 
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate AMBN:
    hsa-miR-3163 hsa-miR-4276
    SwitchGear 3'UTR luciferase reporter plasmidAMBN 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMBN


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AMBN

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion ISS--
    GO:0008283cell proliferation ISS--
    GO:0030282bone mineralization NAS--
    GO:0042475odontogenesis of dentin-containing tooth IEA--

    AMBN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AMBN

    Search CenterWatch for drugs/clinical trials and news about AMBN

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AMBN gene: 
    NM_016519.5  

    Unigene Cluster for AMBN:

    Ameloblastin (enamel matrix protein)
    Hs.272396  [show with all ESTs]
    Unigene Representative Sequence: NM_016519
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322937(uc003hfl.3) ENST00000449493
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AMBN
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate AMBN:
    hsa-miR-3163 hsa-miR-4276
    SwitchGear 3'UTR luciferase reporter plasmidAMBN 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AMBN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AMBN
    Clone
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    GenScript: all cDNA clones in your preferred vector: AMBN (NM_016519)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AMBN
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                         Customized lentivirus expression plasmids for stable overexpression of AMBN 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for AMBN
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AMBN

    Additional mRNA sequence: 

    AF209780.1 AF219994.2 AF263464.1 AJ537437.1 AK314918.1 BC106931.1 BC106932.1 

    1 DOTS entry:

    DT.91666448 

    15 AceView cDNA sequences:

    NM_016519 AF263464 AJ537437 AF219994 BG208788 AF209780 BG213392 BG208157 
    BG195227 BG218715 BG200369 BG190153 BG186598 BG194708 BG214473 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for AMBN    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                          
    SP2:                                -                                                         


    ECgene alternative splicing isoforms for AMBN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AMBN expression in normal human tissues (normalized intensities)      AMBN embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCATTTCCAA
    AMBN Expression
    About this image


    AMBN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Tooth (Integumentary System)    fully expand to see all 2 entries
             Early Ameloblasts Dental Enamel
     
     Heart (Cardiovascular System)
             DKK1-induced cells ( Derivation of cardiomyocytes from pluripotent stem cells and...
     
     Endothelium (Cardiovascular System)
             blood vessel   
     
     Bone (Muscoskeletal System)
             Zeugopod Periosteum

    See AMBN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AMBN

    SOURCE GeneReport for Unigene cluster: Hs.272396

    UniProtKB/Swiss-Prot: AMBN_HUMAN, Q9NP70
    Tissue specificity: Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath
    space between rod-interrod enamel

        SABiosciences Custom PCR Arrays for AMBN
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMBN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for AMBN gene from 1/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ambn1 , 5 ameloblastin1, 5 77.72(n)1
    65.84(a)1
      5 (43.63 cM)5
    116981  NM_009664.11  NP_033794.11 
     884560115 


    ENSEMBL Gene Tree for AMBN (if available)
    TreeFam Gene Tree for AMBN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/464 SNPs in AMBN are shown (see all 464)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1808192351,2
    Cuntested171467214(+) GAAACA/C/TTTTTC 2 P L mis10--------
    VAR_0140694
    ----see VAR_0140692 H R mis40--------
    VAR_0140664
    ----see VAR_0140662 M T mis40--------
    rs1133447921,2
    F--71456022(+) AAAACG/ATCATT 1 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs285710941,2
    C,F--71456088(+) TTTGCC/TAGTTT 1 -- us2k18Minor allele frequency- T:0.27WA NA CSA EA 368
    rs355753971,2
    C--71456114(+) AGCTCG/ATTCCT 1 -- us2k14Minor allele frequency- A:0.11NA WA EA 360
    rs1460445171,2
    --71456129(+) ATTCAA/GCATCA 1 -- us2k10--------
    rs1176874871,2
    C,F--71456203(+) AGCTGC/TCAGCA 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs106341551,2
    C--71456224(+) TCCAG-/CA/CA 
    CACACACA
    cacac
    1 -- us2k10--------
    rs1437160091,2
    C--71456224(+) TCCAG-/CACACACACA
    CACACACACACA
    CACAC
    1 -- us2k10--------

    HapMap Linkage Disequilibrium report for AMBN (71457973 - 71473005 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for AMBN:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4379CNV Insertion18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing AMBN
    DNA2.0 Custom Variant and Variant Library Synthesis for AMBN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601259    OMIM disorders: --

    3 diseases for AMBN:    About MalaCards
    dental pulp necrosis    dentin dysplasia    amelogenesis imperfecta

    2 diseases from the University of Copenhagen DISEASES database for AMBN:
    Amelogenesis imperfecta     Dentin dysplasia

    AMBN for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for AMBN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    amelogenesis imperfecta 95.7 7 11330937 (2), 12657627 (2), 9126491 (1), 9189626 (1) (see all 5)
    ameloblastoma 63.2 12 17331365 (3), 19648121 (2), 15288841 (1), 11054529 (1)
    tumors 3.79 2 17331365 (2)

    Genetic Association Database (GAD): AMBN
    Human Genome Epidemiology (HuGE) Navigator: AMBN (1 document)

    Export disorders for AMBN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AMBN gene, integrated from 9 sources (see all 66):
    (articles sorted by number of sources associating them with AMBN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, characterization and immunolocalization of human ameloblastin. (PubMed id 10946765)1, 2, 9 MacDougall M.... Berdal A. (2000)
    2. Ameloblastin gene (AMBN) maps within the critical region for autosomal dominant amelogenesis imperfecta at chromosome 4q21. (PubMed id 9126491)1, 3, 9 MacDougall M....Forsman K. (1997)
    3. Human ameloblastin gene: genomic organization and mutation analysis in amelogenesis imperfecta patients. (PubMed id 11330937)1, 2, 9 Mardh C.K.... Forsman-Semb K. (2001)
    4. Cloning and characterization of the human ameloblastin gene. (PubMed id 11054529)1, 2, 9 Toyosawa S.... Ijuhin N. (2000)
    5. Enamel formation genes are associated with high caries experience in Turkish children. (PubMed id 18781068)1, 4, 9 Patir A....Vieira A.R. (2008)
    6. Bioinformatic analysis and molecular modelling of human ameloblastin suggest a two-domain intrinsically unstructured calcium-binding protein. (PubMed id 18353005)1, 9 Vymetal J....Lyngstadaas S.P. (2008)
    7. Ameloblastin expression in rat incisors and human tooth germs. (PubMed id 9032019)1, 9 Lee S.K....Yamada Y. (1996)
    8. [Mutation and polymorphism of the ameloblastin gene in ameloblastomas] (PubMed id 17331365)1, 9 Niu C.H. and Li T.J. (2006)
    9. Mutation of ameloblastin gene in calcifying epithelia l odontogenic tumor. (PubMed id 19661317)1, 9 PerdigALo P.F....Gomez R.S. (2009)
    10. Identification of a fibronectin interaction site in t he extracellular matrix protein ameloblastin. (PubMed id 20043904)1, 9 Beyeler M....Trueb B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 258 HGNC: 452 AceView: AMBN Ensembl:ENSG00000178522 euGenes: HUgn258
    ECgene: AMBN H-InvDB: AMBN

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AMBN Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for AMBN Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AMBN gene:
    Search GeneIP for patents involving AMBN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AMBN
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     Regulatory tfbs in AMBN promoter
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     Browse Sino Biological Proteins and Antibodies
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     Proteins for AMBN
     Antibodies for AMBN
     ELISAs for AMBN
     CLIAs for AMBN
     Search LifeMap BioReagents cell lines for AMBN
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AMBN
     SwitchGear 3'UTR luciferase reporter plasmids for AMBN
     SwitchGear Promoter luciferase reporter plasmids for AMBN
     Search ThermoFisher Antibodies for AMBN
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AMBN
     inGenious Targeting Laboratory - Custom generated mouse model solutions for AMBN
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AMBN
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     LSBio Antibodies in human, mouse, rat for AMBN
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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